GENERAL ASPECTS RELATED TO THE TECHNOLOGY TRANSFER, THE MAIN SOURCE OF INNOVATION AND DEVELOPMENT AMONG ECONOMIC OPERATORS

Efficient actions carried out in technology transfer bring major benefits to all parties involved in the process.Increasing the technological endowment through the process of technological transfer from research to industrycontributes significantly to the improving of the economic growth rate at the national and regional levels.Universities and research institutions as providers of knowledge are able to supplement their incomes andachieve financial autonomy in order to conduct entrepreneurial activities and research. They can also obtainother collateral benefits such as attracting research contracts sponsored by some economic operators, the abilityto hire and retain top personnel and researchers. Romania, in terms of technology transfer and innovationactivities among economic operators, is still trying to catch the significant gap compared to other Europeancountries. In these conditions technology transfer processes must be well understood and put into practice bothat research institutions as well as at the economic agents

Aspects regarding the efficiency of technology transfer from the national research institutes towards the industry in order to accelerate the development of Romanian economy

Currently, Romania is faced with problems regarding closing the deep economic gap between it and the rest of the EU members. In addition, Romania is concerned with overcoming the difficulties generated by the current economic crisis. The technology transfer of the research results from the scientific field towards the industry is one of the main leverages for the economic development, the innovation development and the competitiveness of the companies. At this point, Romania marks a very low transfer rate of technology between the research institutions and the economy. This is why, increasing and accelerating this rate becomes a vital element for the Romanian economy. The national research institutes are one of the most representative institutions of the national research and development system. With a high capacity of generating scientific results specific to certain national areas of expertise, their potential of transfering technology should be exploited and made more efficient. This paper presents a synthesis of the written works regarding the technology transfer, its role in the economic growth and the factors influencing its efficiency. The paper performs an analysis the current state of the national research institutes and formulates hypotheses regarding the causes leading to the low technology transfer rate, making suggestions on further research studies on how to turn this important process into a more efficient on

Mental Health within the LGBTQ+ Population

Depression and anxiety are the leading mental health issues that impact the LGBTQ+ population as a direct correlation with the discrimination and marginalization they experience due to their sexuality and/or gender identity. Our goal is to raise awareness of the most common mental health issues that are prominent within this particular population. Along with suggested advocacy efforts to help alleviate the larger-scale issue of oppression and discrimination faced by LGBTQ+ individuals. Suggested advocacy efforts include but are not limited to: anti-discrimination legislation, best practices including cultural competency and affirmative practice in all health care professions. Mental health impacts all areas of society, therefore, all of us have an obligation and duty to have a culturally competent understanding of mental health with all populations. Furthermore, it is critical that LGBTQ+ individuals and allies have the knowledge of resources and tools available for mental health services. Diana Maier and Ashley Hill are first-year master's students at The Ohio State University College of Social Work. Diana has a Bachelor of Arts in youth ministries and recreation from Bluffton University and is a graduate of the Vineyard Leadership Institute. Diana currently serves as a program coordinator with OSU Extension 4-H Youth Development. She is passionate about confronting the stigma surrounding mental health issues and supporting individuals and families impacted specifically by depression. She is also interested in suicide prevention efforts. Ashley has a Bachelor of Arts in psychology from Notre Dame College. Ashley currently serves as the clinic coordinator, MIPS coordinator and wellness innovator at the Ohio State College of Optometry. She has a passion for clinical social work and the desire to help advocate for change specifically within the LGBTQ+ population by addressing the unique challenges that LGBTQ+ individuals face as an oppressed population.AUTHOR AFFILIATION: Ashley Hill, Clinical Coordinator, Ohio State College of Optometry, [email protected] (Corresponding Author); Diana Maier, The Ohio State University Extension Program Coordinator, 4-H Youth Development, State 4-H Office.Depression and anxiety are the leading mental health issues that impact the LGBTQ+ population, directly correlated with discrimination and marginalization they experience due to their sexuality and/or gender identity. Our goal is to raise awareness of the most common mental health issues within this population, as well as suggested advocacy efforts to help alleviate the larger-scale issue of oppression and discrimination faced by LGBTQ+ individuals. Suggested efforts include but are not limited to: anti-discrimination legislation and best practices that include cultural competency and affirmative practice in all health care professions. It is also critical that LGBTQ+ individuals and allies know what resources and tools are available for mental health services

Serum triiodothyronine levels and inflammatory cytokine production capacity

Increasing evidence suggests that pro-inflammatory cytokines are at play in lowering peripheral thyroid hormone levels during critical illness. Conversely, thyroid hormones have been suggested to enhance production of inflammatory cytokines. In view of these considerations, we hypothesized a mutual association between triiodothyronine and pro-inflammatory cytokines. Therefore we evaluated the relation between both circulating and induced inflammatory markers and serum thyroid function parameters in the Leiden 85-plus Study. We found that higher circulating levels of inflammatory markers were associated with lower levels of free serum triiodothyronine. In turn, higher serum free triiodothyronine levels were related to higher production capacity of pro-inflammatory cytokines after stimulation with lipopolysaccharide. By combining in vivo and ex vivo data, we were able to demonstrate for the first time the existence of a potential feedback mechanism between thyroid function and immune production capacity. We conclude that maintenance of normal thyroid function might be important for a preserved immune response in elderly human populations

Prevalence and Characteristics of Self-Reported Hypothyroidism and Its Association with Nonorgan-Specific Manifestations in US Sarcoidosis Patients: A Nationwide Registry Study

Little is known about the prevalence, clinical characteristics and impact of hypothyroidism in patients with sarcoidosis. We aimed to determine the prevalence and clinical features of hypothyroidism and its relation to organ involvement and other clinical manifestations in patients with sarcoidosis. We conducted a national registry-based study investigating 3835 respondents to the Sarcoidosis Advanced Registry for Cures Questionnaire between June 2014 and August 2019. This registry is based on a self-reported, web-based questionnaire that provides data related to demographics, diagnostics, sarcoidosis manifestations and treatment. We compared sarcoidosis patients with and without self-reported hypothyroidism. We used multivariable logistic regression and adjusted for potential confounders to determine the association of hypothyroidism with nonorgan-specific manifestations. 14% of the sarcoidosis patients self-reported hypothyroidism and were generally middle-aged white women. Hypothyroid patients had more comorbid conditions and were more likely to have multiorgan sarcoidosis involvement, especially with cutaneous, ocular, joints, liver and lacrimal gland involvement. Self-reported hypothyroidism was associated with depression (adjusted odds ratio (aOR) 1.3, 95% CI 1.01–1.6), antidepressant use (aOR 1.3, 95% CI 1.1–1.7), obesity (aOR 1.7, 95% CI 1.4–2.1), sleep apnoea (aOR 1.7, 95% CI 1.3–2.2), chronic fatigue syndrome (aOR 1.5, 95% CI 1.2–2) and was borderline associated with fibromyalgia (aOR 1.3, 95% CI 1–1.8). Physical impairment was more common in patients with hypothyroidism. Hypothyroidism is a frequent comorbidity in sarcoidosis patients that might be a potentially reversible contributor to fatigue, depression and physical impairment in this population. We recommend considering routine screening for hypothyroidism in sarcoidosis patients especially in those with multiorgan sarcoidosis, fatigue and depression

SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany

The project focuses on the efficiency of combined technologies to reduce the release of micropollutants and bacteria into surface waters via sewage treatment plants of different size and via stormwater overflow basins of different types. As a model river in a highly populated catchment area, the river Schussen and, as a control, the river Argen, two tributaries of Lake Constance, Southern Germany, are under investigation in this project. The efficiency of the different cleaning technologies is monitored by a wide range of exposure and effect analyses including chemical and microbiological techniques as well as effect studies ranging from molecules to communities

Diet-induced loss of adipose Hexokinase 2 triggers hyperglycemia

Chronically high blood glucose (hyperglycemia) leads to diabetes, fatty liver disease, and cardiovascular disease. Obesity is a major risk factor for hyperglycemia, but the underlying mechanism is unknown. Here we show that a high fat diet (HFD) in mice causes early loss of expression of the glycolytic enzyme Hexokinase 2 (HK2) specifically in adipose tissue. Adipose-specific knockout of Hk2 caused enhanced gluconeogenesis and lipogenesis in liver, a condition known as selective insulin resistance, leading to glucose intolerance. Furthermore, we observed reduced hexokinase activity in adipose tissue of obese and diabetic patients, and identified a loss-of-function mutation in the hk2 gene of naturally hyperglycemic Mexican cavefish. Mechanistically, HFD in mice led to loss of HK2 by inhibiting translation of Hk2 mRNA. Our findings identify adipose HK2 as a critical mediator of systemic glucose homeostasis, and suggest that obesity-induced loss of adipose HK2 is an evolutionarily conserved, non-cell-autonomous mechanism for the development of hyperglycemia