Copy-number variation of housekeeping gene rpl13a in the hippocampus and bone marrow of rat strains selected for nervous system excitability

Genomic structural differences among individuals, particularly copy number variation (CNV), are of great importance in the exploration of mammalian diversity and evolution. CNV is implicated in diverse human diseases including nervous system, neurological, and autoimmune disorders. Here, we aimed to detect and evaluate CNV for four genes: grin1 that is multifunctional in the regulation of normal and pathological brain functions; three housekeeping genes with stable expression, gapdh, rpl13a, and ywhaz. These were examined in rat strains differing in excitability of the nervous systems. The rpl13a copy number is significantly reduced in both the hippocampus and bone marrow in rats with a high excitability threshold (HT). In bone marrow of rats with a low excitability threshold (LT), there is a two fold increase in the rpl13a copy numbervs Wistar rats. Stress is also connected to a decrease rpl13a copy number in the bone marrow of HT ( emotional hypokinetic stress) and Wistar rats (emotional painful stress). The observed phenomenon may be associated with the role of rpl13 a in lipid metabolism; synaptic membranes of the HT cerebral cortex had significantly higher amounts of sphingomyelin and phosphatidylcholine.Peer reviewe

Interpopulation Heterogeneity of Deschampsia antarctica Desv According to the Variability of Nuclei Areas and Relative Level of DNA in Different Tissues of Leaves

The objective of the present work was to analyze diversity in several sub-Antarctic populations studying the morphological variability of the average nucleus area in the D. antarctica leaf epidermis and palisade parenchyma and to assess the ability for polysomaty in these tissues. The investigated material gathered on 5 islands of sub-Antarctica: Petermann, Berthelot, Galindez, Rasmussen and Yalour, thus the populations experienced quit different conditions.Целью этого исследования было изучение наличия полисоматии в тканях листа D. antarctica, а также анализ межпопуляционной изменчивости по величине средней площади ядра и относительного содержания ДНК в ядрах клеток эпидермальной и паренхимной тканей листка D. antarctica. В исследовании использовали материал, собранный в марте 2005 г. на пяти островах Субантарктики: Петерман, Бертелот, Галиндез, Расмуссен и Ялур.Метою цього дослідження було вивчити наявність полісоматії в тканинах листка D. antarctica, а також проаналізувати міжпопуляційну мінливість за величиною середньої площі ядра та відносного вмісту ДНК в ядрі клітин епідермальної та паренхімної тканин листка цієї рослини. В дослідженні використовували матеріал, зібраний в березні 2005 р. на п’ятьох островах Субантарктики: Петерман, Бертелот, Галіндез, Расмуссен та Ялу

Organization of surgical assistance to wounds with fire-fighting defects of soft tissues at the levels of medical security

Taking into account the implementation of NATO standards in the Armed Forces of Ukraine, medical support of troops in the main group during the environmental protection was carried out at four levels

Unified time analysis of photon and (nonrelativistic) particle Tunnelling, and the Superluminal group-velocity problem

A unified approach to the time analysis of tunnelling of nonrelativistic particles is presented, in which Time is regarded as a quantum-mechanical observable, canonically conjugated to Energy. The validity of the Hartman effect (independence of the Tunnelling Time of the opaque barrier width, with Superluminal group velocities as a consequence) is verified for ALL the known expressions of the mean tunnelling time. Moreover, the analogy between particle and photon tunnelling is suitably exploited. On the basis of such an analogy, an explanation of some recent microwave and optics experimental results on tunnelling times is proposed. Attention is devoted to some aspects of the causality problem for particle and photon tunnelling.Comment: plain (old) LaTeX; 42 pages; plus figures 1, 2, 3, 4a, 4b, and

Multipolar model of bremsstrahlung accompanying proton-decay of nuclei

Emission of bremsstrahlung photons accompanying proton decay of nuclei is studied. The new improved multipolar model describing such a process is presented. The angular formalism of calculations of the matrix elements is stated in details. The bremsstrahlung probabilities for the $^{157}{\rm Ta}$, $^{161}{\rm Re}$, $^{167}{\rm Ir}$ and $^{185}{\rm Bi}$ nuclei decaying from the $2s_{1/2}$ state, the $^{109}_{53}{\rm I}_{56}$ and $^{112}_{55}{\rm Cs}_{57}$ nuclei decaying from the $1d_{5/2}$ state, the $^{146}_{69}{\rm Tm}_{77}$ and $^{151}_{71}{\rm Lu}_{80}$ nuclei decaying from the $0h_{11/2}$ state are predicted. Such spectra have orders of values similar to the experimental data for the bremsstrahlung photons emitted during the $\alpha$-decay. This indicates on real possibility to study bremsstrahlung photons during proton decay experimentally and perform further measurements.Comment: 14 pages, 6 figure

Мультимодальний підхід при реконструкції вогнепальних дефектів м'яких тканин передпліччя та зап'ястку

According to the literature, gunshot extremities wounds are most frequent among combat trauma and affect up to 62.2% of the patients. The total rate of gunshot upper extremities wounds is high too – near of 25.7% [1], in particular during local military conflicts. Provision of effective medical tactics allow to return the serviceman to service and expand the reserve of experienced personnel in Armed Forces. The forearm–hand area has a high functional value. It contains a large number of mobile anatomical elements, the complex structure of connective tissue, vascular and nervous structures. In this regard, the treatment of damage to this area is a significant clinical problem that requires a long and hard work. At the same time, active surgical tactics to accelerate the restoration of anatomical – functional integrity of the upper extremity [1–9] is necessary, as the complexity and fragility of the anatomical structure cause significant limitation of hand function even due to minor, at first glance, scarring

Multiple internal reflections during particle and photon tunneling

We discuss the time analysis of multiple internal reflections during one-dimensional tunneling of non-relativistic particles and photons with sub-barrier energies through potential barriers. The approach exploited is a simple analytic continuation from real (over-barrier) wave numbers to imaginary (sub-barrier) wave numbers. It is shown in particular that not only the general effective tunneling velocity, but also every effective transmission (tunneling) velocity for at least the first intermediate stage between successive internal reflections is superluminal. An interpretation of this seemingly strange fact is given in terms of an effective deformation of spacetime inside the barrier. The results obtained are interpreted with the help of the Fourier expansion over the virtual momentum space. A comparison with the instanton approach is also made