MELANOMA? OBSERVE MAIS PERTO

Pigmented skin lesions are sometimes misdiagnosed due to clinical similarities between melanocytic and non-melanocytic lesions. We report the case of a patient with a pigmented lesion that clinically resembles melanoma. With dermoscopy, observed features, namely leaf-like areas, allowed us to make the diagnosis of pigmented basal cell carcinoma. This case represents a clinical setting in which clinical examination alone could lead to a misdiagnosis, but with the use of dermoscopy an accurate diagnosis was possible.Lesões cutâneas pigmentadas por vezes são mal diagnosticadas devido às semelhanças entre as lesões melanocíticas e não-melanocíticas. Relatamos o caso de um doente com uma lesão pigmentada, clinicamente sugestiva de melanoma. Quando analisada com dermatoscopia, é possível observar características, nomeadamente áreas “leaf-like”, que nos permitem fazer o diagnóstico de carcinoma basocelular pigmentado. Este caso representa uma situação clínica em que o exame clinico isoladamente pode levar a um diagnóstico incorreto, mas que com o apoio da dermatoscopia foi feito corretamente

Gestió de projectes experimentals al laboratori

Els plans d’estudi d'Enginyeria Química tenen assignatures troncals exclusivament de laboratori. Tot i així, la visió tradicional de la docència al laboratori continua essent la d’unes pràctiques complementàries a les assignatures teòriques. Tanmateix, es pot dotar aquestes assignatures d'un discurs propi basat en l’experimentació com a mètode i aprofitar el fet que el laboratori, a diferència de l'aula, és un escenari idoni per a l’aprenentatge i desenvolupament de competències, actituds i aptituds més enllà de la repetició del procés de mesura i del coneixement dels fonaments fisicoquímics dels fenòmens i processos que s’estudien. Des de fa més de deu anys l’Experimentació en Enginyeria Química de l’EUETIB s’ha plantejat com un procés de millora continua vers aquest objectiu. La formulació d’un pla estratègic que en gestionava la transformació va ser premiada el 2007 i actualment incorpora de manera explícita una sèrie de jocs de rol al laboratori orientats a l’aprenentatge de competències en l’àmbit de l’aplicació del mètode científic, la resolució de problemes, la gestió de projectes, la gestió de la qualitat i la millora contínua, la gestió de la seguretat i el medi ambient, la coavaluació i l’avaluació per a l’aprenentatge i la comunicació i el llenguatge.Peer Reviewe

Rey–Osterrieth Complex Figure – copy and immediate recall (3 minutes): Normative data for Spanish-speaking pediatric populations

OBJECTIVE: To generate normative data for the Rey–Osterrieth Complex Figure (ROCF) in Spanish-speaking pediatric populations. METHOD: The sample consisted of 4,373 healthy children from nine countries in Latin America (Chile, Cuba, Ecuador, Guatemala, Honduras, Mexico, Paraguay, Peru, and Puerto Rico) and Spain. Each participant was administered the ROCF as part of a larger neuropsychological battery. The ROCF copy and immediate recall (3 minutes) scores were normed using multiple linear regressions and standard deviations of residual values. Age, age2, sex, and mean level of parental education (MLPE) were included as predictors in the analyses. RESULTS: The final multiple linear regression models showed main effect for age on copy and immediate recall scores, such that scores increased linearly as a function of age. Age2 affected ROCF copy score for all countries, except Puerto Rico; and ROCF immediate recall scores for all countries, except Chile, Guatemala, Honduras, Paraguay, and Puerto Rico. Models indicated that children whose parent(s) had a MLPE >12 years obtained higher scores compared to children whose parent(s) had a MLPE≤12 years for Chile, Puerto Rico, and Spain in the ROCF copy, and Paraguay and Spain for the ROCF immediate recall. Sex affected ROCF copy and immediate recall score for Chile and Puerto Rico with girls scoring higher than boys. CONCLUSIONS: This is the largest Spanish-speaking pediatric normative study in the world, and it will allow neuropsychologists from these countries to have a more accurate approach to interpret the ROCF Test in pediatric populations

Gestió de projectes experimentals al laboratori

Postprint (published version

New records of biting midges of the genus Culicoides Latreille (Diptera: Ceratopogonidae) in Argentina

Se brinda un nuevo registro en Argentina de una especie del género Culicoides Latreille, C. pifanoi Ortiz, y también se incluyen los siguientes nuevos registros en la provincia de Misiones de C. chacoensis Spinelli & Wirth, C. plaumanni Spinelli y C. willinki Spinelli & Veggiani Aybar. El número de especies registradas formalmente y reconocidas para Argentina asciende actualmente a 44

Bezzia brevicornis Kieffer

<i>Bezzia brevicornis</i> (Kieffer) <p> <i>Bezzia brevicornis</i> Kieffer, 1917: 328 (male, female; Paraguay); Wirth, 1974: 52 (in catalogue south of USA); Spinelli, 1983: 18; Spinelli & Wirth, 1993: 63 (in list, Argentina); Borkent & Wirth, 1997: 125 (in World catalogue); Spinelli, 1998: 326 (in list, Argentina); Borkent & Spinelli, 2000: 60 (in catalogue south to USA); Borkent & Spinelli, 2007: 93 (in Neotropical catalogue); Spinelli <i>et al.</i>, 2012: 64 (redescription of pupa); Borkent, 2015: 159 (in online World catalogue).</p> <p> <b>Distribution.</b> Paraguay, Argentina (Misiones, Corrientes, Entre Ríos, Buenos Aires, Río Negro), Uruguay. <b>New record.</b> Argentina, Misiones Prov., Posadas, Miguel Lanús, área de Recursos Ambientales El Zaimán, 27° 26' 11.6'' S, 55° 53' 48.7'' W, 28-III-2014, M. Ayala, 1 male (with pupal exuviae).</p>Published as part of <i>Ayala, Mahia M., Spinelli, Gustavo R., Funes, Amparo & Ronderos, María M., 2015, Additional notes on biting midges from the subtropical forest of northeastern Argentina (Diptera: Ceratopogonidae), pp. 79-90 in Zootaxa 3941 (1)</i> on page 89, DOI: 10.11646/zootaxa.3941.1.3, <a href="http://zenodo.org/record/288228">http://zenodo.org/record/288228</a&gt

Culicoides guarani Ronderos & Spinelli

<i>Culicoides guarani</i> Ronderos & Spinelli <p>(Figs. 1–21)</p> <p> <i>Culicoides guarani</i> Ronderos & Spinelli, 1994: 48 (female; Argentina); Borkent & Wirth, 1997: 69 (in World catalogue); Spinelli, 1998: 325 (in list, Argentina); Borkent & Spinelli, 2000: 39 (in catalogue south of USA); Spinelli <i>et al.</i>, 2005: 140, 145 (in key; wing photo); Borkent & Spinelli, 2007: 72 (in Neotropical catalogue); Borkent, 2015: 86 (in online World catalogue).</p> <p>Male adult (Figs. 1–4, 15–16). Head (Figs. 1–2) dark brown. Eyes bare, forming a V-shaped where they contact. Antennae with flagellomeres pale brown, 2–10 fused (Fig. 2); sensilla coeloconica in flagellomeres 1, 11–13. Third palpal segment stout, with deep, rounded subapical sensory pit (Figs. 1–2). Thorax dark brown, scutum without definite pattern, only slightly paler areas laterally. Legs dark brown, knees blackish, fore and midfemora with subapical, tibiae with subbasal narrow pale rings; hind tibial comb with 4 spines, second from spur longest. Wing length 1.00 (0.98–1.02, n = 2) mm, width 0.41 (0.40–0.42, n = 2) mm; pattern as in Fig. 3; CR 0.54 (n = 2); macrotrichia sparse on distal half of wing, none in mcu1 and anal cell; halter brown. Genitalia (Fig. 4): tergite 9 long, tapering, with short, pointed apicolateral processes, distal margin truncate, pair of evident, pilose, median cerci; sternite 9 with narrow, V-shaped, posteromedial excavation. Gonocoxite stout, twice longer than greatest breadth, ventral root foot-shaped, posterior heel evident, dorsal root slender; gonostylus as long as gonocoxite, slender, slightly curved to pointed tip. Parameres (Fig. 15) separate, subparallel, each stout, with strongly sclerotized basal knob; stem curved near base, midportion of stem slightly swollen, nearly straight, distal portion slender, bent ventromesad, taperering to fine point with lateral fringe of stout spines, the portion at the base of the fringe slightly expanded. Aedeagus (Fig. 16) Y-shaped; basal arch pointed caudad, extending to 0.75 of total length; basal arms slender, strongly sclerotized, nearly straight; posteromedial projection lightly sclerotized tapered to slender, broad tip, with pair of conspicuous lateral processes.</p> <p>Male pupa (Figs. 5–6, 8–13). Exuviae general coloration pale brown. Flagellum against lateral margin of face (Fig. 5). Total length 2.20–2.40 (2.31, n=3) mm. Length of cephalothorax 1.00–1.15 (1.07, n= 3) mm, width 0.62 –0.70 (0.65, n= 3) mm. Dorsal apotome (Fig. 6) without ventral line of weakness, dorsomedial tubercle and central dome; slightly wider than long, distal margin truncate, smooth, except for few small wrinkles; disc surface covered by stout rounded spinules; raised areas present; tubercles of dorsal apotome sensilla well-developed, bearing 2 dorsal apotome sensilla as follows: DA-1-H, long, stout seta, DA-2-H campaniform sensillum at tubercle base; DAL 0.13–17 (0.12, n=3) mm; DAW 0.12–0.17 (0.14, n=3) mm; DAW/DAL 0.86–1.26 (0.95, n=3). Cephalothorax rectangular (Fig. 5), surface covered with stout rounded spinules, antenna extending posteriorly to various points along anterior margin of wing; mouthparts (Figs. 11, 17) with mandible, lacinia well developed; palpus extending equal to posterolateral margin of labium; labium separated medially by labrum; apex of labrum rounded. Cephalothoracic sensilla (Figs. 8–11, 17, 19) as follows: one anteriomedial AM-1-T (Fig. 9) minute seta on small tubercle, 2 dorsolateral cephalic sclerite sensilla (Fig.10): DL-1-H long, thin seta, DL-2-H short, stout seta on rounded strong tubercle; 3 anterolaterals (Fig. 8): AL-1-T short, thin seta, Al-2-T long, thin seta, AL-3-T short, stout seta, all sensilla on prominent tubercle; clypeal labrals (Figs: 11, 17): CL-1-H campaniform sensillum, CL-2- H medium-sized, thin seta; oculars (Figs. 11,17): O-1-H, O-3-H long, thin setae, O-2-H campaniform sensillum Respiratory organ (Figs. 5, 8–9) elongated, slender, uniformly brown, medium-sized, circular in cross-section, wider at base, covered with scale-like spinules; 6–7 apical pores, 2–3 lateral; pedicel (Fig. 9) short, stout, P length 0.02–0.03 (0.025, n=3) mm, RO length 0.195–0.20 (0.197, n=3) mm, RO wide 0.025–0.03 (0.027, n=3) mm; P/RO 0.10–0.15 (0.126, n=3); 5 dorsal setae (Fig. 18): D-1-T, D-2-T, D-4-T long, stout setae, D-2-T longer than D-1-T and D-4-T; D-3-T campaniform sensillun, D-5-T minute seta, all setae on rounded tubercles, SA-2-T present. Metathoracics (Fig. 19): M-2-T long, thin seta, M-3-T campaniform sensillum, M-3-T near anterior margin. Abdominal segments with smooth integument, with scarse, scattered spicules on anterior and posterior portions; each segment without pigmentation pattern. First abdominal segment (Figs. 5, 20) with setae as follows: 3 anteromesal setae, D- 2-I short, stout seta, D- 3-I long, thin seta, D- 7-I campaniform sensillum; 3 posterior setae, D- 4-I medium-sized, thin seta, D- 8-I short, thin seta, D- 9-I minute seta; 3 lateral setae: L- 1-I long, thin seta, L- 2-I, L- 3-I campaniform sensilla. Fourth segment (Figs. 5, 21) with dorsal and ventral tubercles with small base: D- 1-IV minute seta, D- 2-IV, D- 3-IV medium-sized, thin setae, D- 3-IV longer and thinner than D- 2-IV; D- 4-IV, D- 7-IV without setae, D- 5-IV, D- 8-IV minute setae, D- 9-IV short, curved seta; V- 1-IV, V- 2-IV campaniform sensilla, V- 5- IV short seta, V- 6-IV long, thin seta, V- 7-IV minute seta, all on notorious pointed lateral tubercles with wide base: L- 1-IV short seta, tubercle smaller than others, L- 4-IV short, stout seta, L- 2-IV, L- 3-IV medium-sized, stout setae. Segment 9 (Figs. 5, 13) approximately 1.14 X longer than greatest width, length 0.20–0.205 (0.202, n= 3) mm, width 0.155–0.185 (0.177, n= 3) mm; posteriorly directed spicules restricted dorsally to mesal area, terminal processes triangular, these moderately elongated, subparallel, pointed; ventral surface of processes spiculate, D- 5- IX, D- 6-IX campaniform sensilla (Fig. 13), genital lobe moderately long, globose, extending under posterior margin.</p> <p>Female pupa (Figs. 7, 14). Similar to male with usual sexual differences. Total length 2.33–2.40 (2.37, n=3) mm. Dorsal apotome (Fig. 7) with DAL 0.14–0.16 (0.15, n=2) mm; DAW 0.125–0.135 (0.13, n=2) mm, DAW/ DAL 0.82–0.90 (0.85, n=2). Respiratory organ: RO length 0.19–0.21 (0.20, n=3) mm, RO width 0.03–0.04 (0.035, n=3) mm; pedicel length 0.025 (n=2) mm, P/RO 0.119–0.125 (0.122, n=2). Cephalothorax length 1.00–1.04 (1.02, n=3) mm, width 0.62– 0.65 (0.64, n=3) mm. Segment 9 (Fig. 14) length 0.20–0.215 (0.207, n=3) mm, width 0.145–0.150 (0.148, n=3) mm; terminal processes (Fig. 14) length 0.065–0.075 (0.072, n=3) mm, width 0.015–0.040 (0.025, n=3) mm.</p> <p> <b>Distribution.</b> Argentina (Misiones).</p> <p> <b>Taxonomic discussion.</b> <i>Culicoides guarani</i> is one of the 14 species included in the <i>Culicoides eublepharus</i> group. All these are known only through adults and seven of them, including <i>C</i>. <i>guarani</i>, just from females.</p> <p> The pupa of this new species is similar to <i>C. debilipalpis</i> Lutz, a species placed in the subgenus <i>Haematomyidium</i> that also breeds in tree holes. However, in the latter species the exuviae is pale yellowish brown, the respiratory organ is yellowish except the distal half brown with its pedicel longer, the posteriorly directed spicules of the caudal segment are restricted to a narrow anterior band and not connected to the mesal inverted Vshaped patch of spicules, and the terminal processes are subparallel with pointed and dark tips. Although the general chaetotaxy is similar, the setae are of cephalothorax and abdomen are thinner and shorter than in <i>C. debilipalpis</i>.</p> <p> The male genitalia of this species is similar to the one illustrated by Wirth & Lee (1967) for <i>C</i>. <i>tamboensis</i> Wirth & Lee, a species inhabiting high altitudes of Colombia except for the sternite 9 with V-shaped and deep caudomedian excavation (very shallow in <i>C</i>. <i>tamboensis</i>) and by the posteromedial projection of the aedeagus without lateral processes. Moreover, the latter species is larger (wing length 1.20 mm), the third palpal segment is shorter, the flagellomere 13 lacks sensilla coeloconica and the halter knob is pale at tip.</p> <p> <i>Culicoides propiipennis</i> Macfie from Mexico to Ecuador, Venezuela and northern Brazil also have very similar genitalia, but the sternite 9 exhibits a very shallow caudomedian excavation, the parameres are convergent and the posteromedial projection of the aedeagus is slender and lacks lateral processes.</p> <p> <b>Specimens examined.</b> Argentina, Misiones Prov., Garupá, Barrio Santa Inés, Estancia Santa Inés, 27° 31' 40.9'' S, 55° 51' 59.4'' W, 9-XI-2013, M. Ayala, 2 males, 3 females (with pupal exuviae).</p>Published as part of <i>Ayala, Mahia M., Spinelli, Gustavo R., Funes, Amparo & Ronderos, María M., 2015, Additional notes on biting midges from the subtropical forest of northeastern Argentina (Diptera: Ceratopogonidae), pp. 79-90 in Zootaxa 3941 (1)</i> on pages 80-81, DOI: 10.11646/zootaxa.3941.1.3, <a href="http://zenodo.org/record/288228">http://zenodo.org/record/288228</a&gt

Bezzia blantoni Spinelli & Wirth

<i>Bezzia blantoni</i> Spinelli & Wirth <p> <i>Bezzia blantoni</i> Spinelli & Wirth, 1989: 771 (male, female, pupa; distribution); Spinelli & Wirth, 1993: 63 (in list, Argentina); Borkent & Wirth, 1997: 125 (in World catalogue); Borkent & Spinelli, 2000: 60 (in catalogue south of USA); Borkent & Spinelli, 2007: 93 (in Neotropical catalogue); Borkent, 2015: 158 (in online World catalogue); Ronderos & Spinelli, 2009: 47 (redescription of pupa).</p> <p> <b>Distribution.</b> Belize to Costa Rica, Puerto Rico, Argentina (Misiones, Corrientes, Buenos Aires).</p> <p> <b>New record.</b> Argentina, Misiones Prov., Posadas, Miguel Lanús, área de Recursos Ambientales El Zaimán, 27° 26' 11.6'' S, 55° 53' 48.7'' W, 28-III-2014, M. Ayala, 4 males, 2 females (with pupal exuviae).</p>Published as part of <i>Ayala, Mahia M., Spinelli, Gustavo R., Funes, Amparo & Ronderos, María M., 2015, Additional notes on biting midges from the subtropical forest of northeastern Argentina (Diptera: Ceratopogonidae), pp. 79-90 in Zootaxa 3941 (1)</i> on page 89, DOI: 10.11646/zootaxa.3941.1.3, <a href="http://zenodo.org/record/288228">http://zenodo.org/record/288228</a&gt

Population fluctuation of Culicoides insignis Lutz (Diptera: Ceratopogonidae) in Posadas, Misiones, Argentina

En Argentina, la distribución de la enfermedad del Virus de la Lengua Azul se encuentra restringida al noreste del país. En la región Neotropical el principal vector sería Culicoides insignis Lutz. El objetivo de este trabajo fue determinar la fluctuación poblacional de C. insignis en la ciudad de Posadas y también la influencia de las variables climáticas como determinantes en la abundancia de esta especie. Los ejemplares fueron capturados mediante trampas de luz en el período comprendido entre enero y diciembre de 2013. La relación entre el número de C. insignis capturados y las variables ambientales fue analizada por regresión lineal multivariada. Se recolectaron 2.952 ejemplares de C. insignis representando el 93,4% del total de Culicoides capturados. Los análisis de regresión lineal multivariada muestran que la humedad relativa media mensual fue la variable que mejor explicó la dinámica de C. insignis en la zona de estudio. La transmisión de patógenos está probablemente influenciada por la abundancia del vector en el área. Los picos poblacionales observados indican los períodos donde debe haber mayor control para evitar la transmisión de la enfermedad. Este es el primer reporte sobre fluctuación poblacional de C. insignis en el noreste del país