C- mac videolaryngoscope: an aide to new findings in Goldenhar Syndrome

Goldenhar Syndrome (GS) is a congenital disorder with male predominance and sporadic occurrence. Various anomalies are seen in these patients involving almost all systems. The anesthesiologist usually finds difficulty in the airway of these patients as a spectrum of anomalies is seen. We report a new finding in the airway of Goldenhar syndrome with the help of a C-Mac videolaryngoscope, with the base of tongue and uvula being bifid and causing inability to intubate in an 11-year-old girl

Survey on Image intensification using Canny Edge Technique

Image Processing is generally done in form of Signal Processing. In this images, pictures, video frame etc are given in Input form and the Output appears with certain set of features or parameters in relation to the input given. Edge Detection using Canny Technique is an set of Mathematical Functions whose main goal is to detect points in the Digital input i.e. image and detect how brightness changes variably , and where are discontinuities. Edge detection is an essential stage in processing the image. Mostly image-processing techniques consider the image as a two-dimensional signal then put standard signal-processing techniques to it. Generally it means Digital Image being processed but analog and digital signals can also be processed

Opioid free anesthesia in a pre-term neonate: A case report

Opioids play a major role in the perioperative management of pain in adults and children. Though there is significant morbidity and mortality associated with overdosage of opioids, they remain the most common means of providing analgesia in the perioperative period. We report the case of a preterm neonate born with low birth weight who underwent high sigmoid loop colostomy for high anorectal malformation using opioid-free general anesthesia with supplementation with caudal block. Successful uncomplicated extubation of preterm baby was achieved with good spontaneous efforts. Opioid free general anesthesia can prevent respiratory depression and the need for postoperative mechanical ventilation even when given to preterm neonates

PULSAR DETECTION SYSTEM USING RADIO TELESCOPE

Radio astronomers and Researchers have detected numerous neutron stars in our galaxy, and they also predicted the Existence of many more neutron stars in space. Pulsars are very peculiar, yet almost inscrutable celestial objects. This is an object which is impelling radiation into space closest to the speed of light. Neutron stars are the most interesting galactic bodies to mankind. The things that hold us during the whole study are the fascinating properties of pulsar i.e. high density, a small diameter, strong gravity, and strong magnetic field. As the peculiar properties and the extreme nature of pulsar continue to disclose this catches the attention of Astronomers. Pulsars are distant objects. So, it is very tedious job to capture the radiations coming from it for this we have designed a system which consist of an Antenna, Filters, Amplifiers and Receiver. The signal we capture through the antenna will undergo signal processing to extract the Pulse which is buried in noise. The techniques used here are the fast-folding algorithm (FFA) and Fast Fourier transform (FFT) are explained along. By this whole study to building a system and performed signal processing and obtained the Pulse

Study of fetomaternal outcome in pre-eclampsia at tertiary care centres, South Gujarat

Background: Hypertensive disorders are among the most common medical disorder during pregnancy and continue to be a serious challenge in obstetric practice. It affects about 7-15% of all gestations. In India it accounts for the third most important cause of maternal mortality. Aim if this study was to study the prevalence of pre-eclampsia and feto-maternal outcome in cases of pre-eclampsia. Methods: This was a descriptive observational study conducted over a period from February 2019 to July 2021. This study enrolled 106 cases of pre-eclampsia, cases were selected by inclusion and exclusion criteria, data were entered and analysed by using SPSS version 20. Results: A total of 106 patients were analysed. It was observed that it was more common in age group of 26 to 30 years 51%, 56% were unbooked patients. Maximum number of patients were primigravida 60%, 96% patients were from lower socioeconomic class, 37% patients had normal vaginal delivery, 63% had caesarean delivery. The most common maternal complication was eclampsia (12%), HELLP Syndrome 12%, abruptio occurred in 8% of patients. Maternal mortality occurred in 4 cases. Out of 106 babies 37 (34.93%) babies had normal outcome while 29% (27.35%) had low birth weight, 16 (15.09%) babies were IUGR, 15 (14.5%) babies were IUFD, 7 (6.6%) babies had RDS and 2 (1.8%) babies were stillbirth 40 (44.94%) babies were admitted in NICU. Conclusions: This study concludes that foetal and maternal outcome were markedly affected by pre-eclampsia and also the grave complications were more common in pre-eclampsia. So proper antenatal care, early diagnosis of pre-eclampsia and timely intervention will decrease maternal perinatal morbidity and mortality

Prevalence and Antimicrobial Susceptibility Pattern of ESBL Producing Gram Negative Bacilli: An Institutional Based Study

Introduction: The production of extended-spectrum- β lactamases (ESBLs) is an important mechanism for resistance to the third generation cephalosporins. Awareness and the detection of these enzymes are necessary for optimal patient care.Methodology: The total of 96 isolates which were isolated from the different samples tested for ESBL production. This study was conducted in Department of Microbiology, Heritage institute of Medical Sciences.Result: This result of this study revealed those 69.7% organisms which were ESBL producers & 30.2% organisms which were non ESBL producers.Conclusion: It is essential to report ESBL production along with the routine sensitivity reporting, which will help the clinician in prescribing the proper antibiotics

Conformationally restricted peptides: solution conformation of tetra and hepta peptides containing α,β-dehydrophenylalanine residues in alternate positions

Two model peptides containing dehydrophenylalanine, a tetrapeptide 1 (Ac- &#916;<SUP>z</SUP>Phe-Pro-&#916;<SUP>z</SUP>Phe-Ala-OMe) and a heptapeptide 2 (Boc-Gly-&#916;<SUP>z</SUP>Phe-Val-&#916;<SUP>z</SUP>Phe-Ala-&#916;<SUP>z</SUP>Phe-Leu-OMe) have been synthesised and their solution conformations investigated by NMR and circular dichroism techniques. Assignment of amide protons and their involvement in intramolecular hydrogen bonding have been made by solvent and temperature dependence studies. These conformation studies indicate the presence of an incipient 3<SUB>10</SUB>-helix in tetrapeptide 1, with two consecutive &#946;-turns and a right handed 3<SUB>10</SUB>-helix in heptapeptide 2. The results establish the potential of &#916;<SUP>z</SUP>Phe residues to favour 3<SUB>10</SUB>-helical conformations with &#948;<SUP>z</SUP>Phe occupying alternate positions in the peptide. A comparison of solution conformation of analogous peptides containing Aib residue in place of &#916;<SUP>z</SUP>Phe is also presented. These residues appear to induce similar conformation constraints in small peptides

The assessment of factors influencing Big data adoption and firm performance: Evidences from emerging economy

The current study investigates and prioritizes 17 determinants of big data adoption (BDA) and establishes causality between these determinants’ and firms’ performance in the tourism and hospitality sector using technology, organisation & environment (TOE) framework. Semi-structured interviews and multi-criteria decision-making (MCDM) were utilized to gather data from 28 industry experts. “Big data quality” ranked as the most influential determinant, while “trading partner pressure” ranked as the least influential determinant. This study’s findings highlight the need for governments across the globe to propose and implement policies to reduce the digital divide and enhance standardization