288 research outputs found

    On the Widening Transfer Aspiration-Achievement Gap: Contextualizing the Transfer Intentions of Community College Students in New Mexico

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    This study examines the character and potential changes of transfer intention to attend four-year institutions among community college students in New Mexico. Since the early 1970s, national transfer achievement rates have declined in spite of high transfer aspirations resulting in a widening national transfer aspiration-achievement gap. Given that initial education expectations are often unmet, I study how the variability of students development and maintenance of transfer intentions may partly account for the gap. This project, designed as an inductive descriptive study, pursues one central research question: What does transferring mean to students? This question elicits more inquiry: How does a student\u27s intention to transfer vary due to underlying socio-cultural processes? Within the respective institutional and demographic contexts, what are the most salient processes at the student level? Do these processes differ in nature or outcome when accounting for different intersections of gender, race and ethnicity, or socio-economic status? Using concepts from Multicontext theory and Social and Cultural Capital theories, I evaluate the descriptive and exploratory findings of a local survey-interview study on community college students\u27 transfer intentions. Beginning with insights gained from two social capital indicators and three cultural capital indicators, I found diminishing (and heightening) of transfer intentions associated with these five socio-cultural processes, along with other unexpected processes that emerged during the course of my research. My primary finding is that student transfer intentions behave dynamically, are more fragile and recently-formed than expected, and exhibit outcome patterns linked to social and cultural experiences while at the community college. These experiences, as colored by the students\u27 accounts, feature interactions of identity and student culture, emotional and morale support, differing \u27comfort-levels,\u27 and the delicate interplay of financial, family and educational priorities. Finally, I aim to generate theoretical discussion on this relatively under-researched phenomenon—with wide-ranging social mobility implications—which this study shows to be an integral function to narrowing the transfer gap at the individual level

    A Rare Cause of Thrombotic Thrombocytopenia Purpura- (TTP-) Like Syndrome, Vitamin B12 Deficiency: Interpretation of Significant Pathological Findings

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    Thrombotic thrombocytopenia purpura (TTP) is a hematological emergency that requires rapid assessment followed by prompt initiation of therapy due to high mortality associated with delayed treatment. TTP has many causes including heritable syndromes, ADAMTS13 deficiency, and drugs-related etiologies. Profound vitamin B12 deficiency can, in rare cases, mimic TTP in presentation, and since plasmapheresis can be of limited benefit, prompt diagnosis is necessary for accurate treatment with B12. Therefore, careful analysis of all clinical signs, symptoms, and labs must be assessed. We report a patient who presented with a diagnosis of TTP, and repeat assessment confirmed a diagnosis of sever vitamin B12 (B12) deficiency with pancytopenia who was appropriately treated with B12.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

    The Effect of Retirement Incentives on Retirement Behavior: Evidence from the Self-Employed in the United States and England

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    In this paper, we examine how public and private pension and health insurance systems affect the retirement transitions. In many countries, public and private pension eligibility, as well as access to health insurance varies between self-employed and wage and salary workers, and these differences are likely to cause differential retirement patterns both within and across countries. We use the variation in these institutional features within and across the United States and England to analyze retirement patterns. Based on longitudinal data from the Health and Retirement Study (HRS) in the United States and the English Longitudinal Survey of Ageing (ELSA) we find that the higher labor force exit rate of wage and salary workers compared to self-employed workers is due to defined benefit pension incentives created by the public and private pension systems. Higher rates of labor force exit at ages 55 and older in England compared to the United States are due in part to the availability of publicly provided health insurance.Social Security Administrationhttp://deepblue.lib.umich.edu/bitstream/2027.42/57567/1/wp155.pd

    Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling

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    Protein domains are the basic units of protein structure and function. Comparative analysis of genomes and proteomes showed that domain recombination is a main driver of multidomain protein functional diversification and some of the constraining genomic mechanisms are known. Much less is known about biophysical mechanisms that determine whether protein domains can be combined into viable protein folds. Here, we use massively parallel insertional mutagenesis to determine compatibility of over 300,000 domain recombination variants of the Inward Rectifier K+ channel Kir2.1 with channel surface expression. Our data suggest that genomic and biophysical mechanisms acted in concert to favor gain of large, structured domain at protein termini during ion channel evolution. We use machine learning to build a quantitative biophysical model of domain compatibility in Kir2.1 that allows us to derive rudimentary rules for designing domain insertion variants that fold and traffic to the cell surface. Positional Kir2.1 responses to motif insertion clusters into distinct groups that correspond to contiguous structural regions of the channel with distinct biophysical properties tuned towards providing either folding stability or gating transitions. This suggests that insertional profiling is a high-throughput method to annotate function of ion channel structural regions

    Low-Tech Riparian and Wet Meadow Restoration Increases Vegetation Productivity and Resilience Across Semiarid Rangelands

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    Restoration of riparian and wet meadow ecosystems in semiarid rangelands of the western United States is a high priority given their ecological and hydrological importance in the region. However, traditional restoration approaches are often intensive and costly, limiting the extent over which they can be applied. Practitioners are increasingly trying new restoration techniques that are more cost‐effective, less intensive, and can more practically scale up to the scope of degradation. Unfortunately, practitioners typically lack resources to undertake outcome‐based evaluations necessary to judge the efficacy of these techniques. In this study, we use freely available, satellite remote sensing to explore changes in vegetation productivity (normalized difference vegetation index) of three distinct, low‐tech, riparian and wet meadow restoration projects. Case studies are presented that range in geographic location (Colorado, Oregon, and Nevada), restoration practice (Zeedyk structures, beaver dam analogs, and grazing management), and time since implementation. Restoration practices resulted in increased vegetation productivity of up to 25% and increased annual persistence of productive vegetation. Improvements in productivity with time since restoration suggest that elevated resilience may further enhance wildlife habitat and increase forage production. Long‐term, documented outcomes of conservation are rare; we hope our findings empower practitioners to further monitor and explore the use of low‐tech methods for restoration of ecohydrologic processes at meaningful spatial scales
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