1,449 research outputs found

    El Empresario del Clúster del Software en Jalisco y su Capital Social

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    El objetivo de este trabajo es identificar el capital social que se construye en Jalisco en el sector estratégicos de desarrollo como es el caso del Software. Para lo cual nos apoyamos en las teorías de Coleman, Bourdieu y Putman. Ya que nos permiten identificar al empresario (Coleman), la estructura social del empresario (Bourdieu), y las redes institucionalizadas para el desarrollo del sector (Putman). &nbsp

    Detection of high-risk human papillomavirus RNA in urine for cervical cancer screening with HPV 16 & 18/45 genotyping

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    © 2020 The Authors Objective: To detect high-risk human papillomavirus (hrHPV) messenger-RNA (mRNA) in urine samples, compare their concordance with cervical samples including HPV 16 & 18/45 genotyping, and to determine the utility in detecting ≥ CIN 2 lesions. Methods: A cohort of 189 non-pregnant patients (age ≥ 25) was recruited in three groups: Group 1 with abnormal pap-smears and hrHPV positivity, Group 2 with normal pap-smears and hrHPV positivity, and Group 3 with normal pap-smears and hrHPV negativity. Urine samples were tested for hrHPV-mRNA and subsequent hrHPV-mRNA genotype if positive. High-risk HPV detection and genotyping were performed using Aptima assays which are validated for cervical HPV testing. Colposcopy results from groups 1 & 2 were analyzed. Results: The sensitivity of urine hrHPV-mRNA detection was 31.5% while the specificity and PPV were above 95% (96.9% & 95.1% respectively) (p \u3c 0.001). The kappa agreement with cervical samples was fair (0.22, p = 0.04). The sensitivity and specificity of urine hrHPV-mRNA genotyping were 20.0% & 100% respectively (p \u3c 0.001) with 100% genotype-specific concordance. The kappa agreement with cervical samples was fair (0.25, p = 0.16). For urine hrHPV-mRNA detection of ASC-H/HSIL when grouped by age ≥ 30, the sensitivity and specificity were 45.4% & 63.9% respectively (p = 0.009). For urine hrHPV-mRNA detection of ≥ CIN 2 for all ages, the sensitivity and specificity were 45.5% & 75.0% respectively (p = 0.03). Conclusion: Using the Aptima Assay, urine hrHPV-mRNA detection is suboptimal for cervical cancer screening but given the high specificity, it has the potential to identify high-grade lesions (≥ CIN 2). Urine hrHPV-mRNA genotyping via this modality is not beneficial in triage settings of normal or abnormal cytology to determine the need for colposcopy

    Efecto de la fertilización sobre la producción de un fruto forestal comestible: el piñón de pino piñonero (Pinus pinea L.) en Andalucía Occidental

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    The pine nut from the stone pine (Pinus pinea L.) is the most important edible fruit in mediterranean forests. Despite this fact, there is a lack of knowledge regarding the application of agronomy techniques in stands of this species to increase pine nut production. Our study focuses on the effect of mineral fertilization on cone production and size, which in turn, are closely related to nut yield and quality. Cone production and quality was analysed in a randomized experiment installed in south west Spain, comparing the effect of different doses of lime superphosphate, dolomite and potassium. A significant short term increase in cone production and quality exists as a consequence of fertilization, especially in those treatments involving the addition of larger quantity of dolomite. Nevertheless, effect of mineral fertilization on cone yield and quality was lower than expected, so further increments might be achieved through nitrogenous and organic fertilizations to improve soil structure in these sandy soils.El piñón de Pinus pinea L. es el fruto forestal comestible más importante en los bosques mediterráneos. Pese a esto, existe una falta de conocimiento científico acerca de la aplicación de prácticas agronómicas sobre las masas forestales de la especie al objeto de mejorar la producción de piñón. Nuestro trabajo se centra en el análisis del efecto de la fertilización mineral sobre la producción y el tamaño de las piñas, variables muy relacionadas con la cantidad y calidad de piñón. Entre 1993-1999 se realizó el seguimiento de la producción y la calidad de la piña en un experimente aleatorizado instalado en el SO de España, donde se comparaban diferentes dosis de superfosfato de cal, dolomita y cloruro potásico. Se ha detectado una respuesta positiva a la fertilización en la cantidad y calidad de las piñas producidas, especialmente en los tratamientos que planteaban la incorporación de una mayor cantidad de dolomita. El efecto de la fertilización mineral sobre la cantidad y calidad de piña ha sido menor que el esperado, por lo que futuros trabajos deben plantear la necesidad de incorporar fertilizantes nitrogenados y materia orgánica para mejorar la estructura en estos suelos arenosos

    Fast Incoherent OFDR Interrogation of FBG Arrays Using Sparse Radio Frequency Responses

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    [EN] We present two implementations of fast, discrete incoherent optical frequency-domain reflectometers (I-OFDR) for the interrogation of equally spaced fiber Bragg grating (FBG) arrays, based on the determination of the array's radio frequency (RF) response at a sparse number of frequencies. FBG reflectivities are determined by use of the inverse discrete Fourier transform (IDFT) of the sparse RF response, in a dynamic range limited by crosstalk induced by FBG positioning errors. The first implementation employs the complete, vector RF response at a number of frequencies equal to the number N of FBGs in the array. In the second, the introduction of a reference reflector allows for an interrogation using the power (phaseless) RF response in 4N - 1 frequencies. Demodulation based on IDFT leads to total interrogation times determined by the network analyzer scan time, which can be as low as 10 mu s per FBG. Depending on the interrogation technique, electrical bandwidth requirements are 12 GHz in our array with 10-cm separation. We implemented both techniques in a N = 10 array, inducing decays in reflectivity by 10 dB in one or several FBGs. Unambiguous detection of FBG decays was obtained in both interrogation methods. Additional tests performed on the measured reflectivities also show that measurement linearity is preserved in the 10-dB decay range. As discrete I-OFDR systems, the proposed techniques show the possibility to reach compromises between interrogation time and dynamic range or accuracy in reflectivity measurements, using the number of interrogation frequencies and the sensor topology.This work was supported in part by Infraestructura GVA-FEDER operative program 2007-2013 and in part by the Spanish MINECO through Project TEC2017-88029-R. The work of J. Clement Bellido was supported by the GVA VALi+d scholarship ACIF/2016/214. The work of J. Hervas was supported by the Spanish MEC scholarship FPU13/04675.Clement, J.; Hervás-Peralta, J.; Madrigal-Madrigal, J.; Maestre, H.; Torregrosa, G.; Fernandez-Pousa, CR.; Sales Maicas, S. (2018). Fast Incoherent OFDR Interrogation of FBG Arrays Using Sparse Radio Frequency Responses. Journal of Lightwave Technology. 36(19):4393-4400. https://doi.org/10.1109/JLT.2018.2821199S43934400361

    Investigating ground-motion duration effects on building portfolio loss estimates

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    Earthquake-induced ground-motion duration can be an important factor to consider when assessing ground-motion damage potential, as evidenced by recent earthquake events worldwide. In current practice, duration is commonly relegated to implicit, qualitative considerations. This study introduces a framework to explicitly quantify the influence of duration on building portfolio direct economic losses. To this end, a simulation-based probabilistic risk modelling framework is developed for different synthetic building portfolios impacted by a case-study seismic source. Two building typologies, representative of distinct vulnerability classes in southern Europe, are considered. A simulation-based probabilistic seismic hazard analysis is performed, explicitly simulating duration jointly with spectral-shape-related intensity measures. Sets of long and one-to-one spectrally-equivalent short duration ground-motion records are selected and then used jointly to perform nonlinear dynamic analysis and derive fragility models for each considered building typology. Fragility relationships are derived by using average spectral acceleration as the primary intensity measure and: 1) maximum inter-storey drift ratio as a demand parameter, indirectly accounting for ground-motion duration (through the adopted nonlinear modelling strategy); 2) maximum inter-storey drift ratio as demand parameter, explicitly considering duration as an intensity measure together with spectral shape, in a vector-valued format. For each case, vulnerability models are developed by combining the fragility relationships with a building-level damage-to-loss model. The portfolio expected annual losses estimated using the described vulnerability models are critically compared and discussed. Depending on the location/portfolio, the impact of ground-motion duration can be significant, and the proposed approaches allow an analyst to account for it in a practical way

    Evaluation of anaerobic digestibility of energy crops and agricultural by-products

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    Abundant wastes from the food and drink supply chain are valuable and infrequently used as anaerobic digestion (AD) substrates. This study quantifies their biomethane potential to contribute to solid waste reduction and energy production. 29 organic materials were evaluated: energy crops (6), pre-treated agricultural by-products (5), livestock slurries (3), agro-industrial wastes (7), fruit and vegetable wastes (4) and co-digestion mixtures of chicken litter (CL) and fruit wastes (4). Results showed highest biogas yields for rendered fat washings (1379 ± 125 mL/g VSfeedstock), fish waste (898 ± 107 mL/g VSfeedstock) and potato waste (768 ± 27 mL/g VSfeedstock). Synergistic benefits of co-digestion were evidenced. CL (20%) with avocado pulp (80%) led to 84% higher biogas than expected from contribution of single substrates

    Dynamic Companion Harmonic Circuit Models for Analysis of Power Systems with Embedded Power Electronics Devices

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    In this paper a methodology that extends the dynamic harmonic domain (DHD) analysis of large networks is presented. The method combines DHD analysis and discrete companion circuit modeling resulting in a powerful analytic technique called dynamic companion harmonic circuit modeling. It provides for a complete dynamic harmonic analysis of the system while preserving the advantages of discrete companion circuit models. The methodology is illustrated by its application to a three-node power system, where reactive power compensation is achieved using a fixed-capacitor, thyristor-controlled reactor (FC-TCR) and its control system

    Plan de negocios para un despacho de arquitectos en Guadalajara, Jalisco

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    Trabajo que presenta un plan de negocios enfocado principalmente a la implementación de soluciones innovadoras e integrales para un despacho de arquitectura especializado en diseño y remodelación de fachadas de residencias, negocios y oficinas. Las oportunidades identificadas para el despacho son: las tecnologías digitales, la construcción innovadora y sustentable, la mejora de la calidad del servicio al cliente y la reducción de costos
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