344 research outputs found
Development of wireless bruxism monitoring device based on pressure-sensitive polymer composite
A wireless pressure sensing bite guard has been developed for monitoring the progress of bruxism (teeth grinding during sleep); as well as protecting the teeth from damages. For sensing the pressure effectively in the restricted space and hostile environment, a pressure sensitive polymer composite has been fabricated and encapsulated into a conventional bite guard which is safe for in-situ applications. The device is anticipated to give real-time data through wireless data transmission and to have a long working life (weeks). A microcontroller-based electronic circuit has been built in-house for data collection and transmission. A low power approach is configured to increase the working life of the device. This device is a useful tool for understanding and treating bruxism
Reply to the comment on "Factor structure of the Rutter Teacher Questionnaire in Portuguese children"
Synthesis and Characterization of Niobium Carbide with Copper Addition Obtained Via Gas Solid Reaction
A meta-analysis of N-acetylcysteine in contrast-induced nephrotoxicity: unsupervised clustering to resolve heterogeneity
<p>Abstract</p> <p>Background</p> <p>Meta-analyses of N-acetylcysteine (NAC) for preventing contrast-induced nephrotoxicity (CIN) have led to disparate conclusions. Here we examine and attempt to resolve the heterogeneity evident among these trials.</p> <p>Methods</p> <p>Two reviewers independently extracted and graded the data. Limiting studies to randomized, controlled trials with adequate outcome data yielded 22 reports with 2746 patients.</p> <p>Results</p> <p>Significant heterogeneity was detected among these trials (<it>I</it><sup>2 </sup>= 37%; <it>p </it>= 0.04). Meta-regression analysis failed to identify significant sources of heterogeneity. A modified L'Abbé plot that substituted groupwise changes in serum creatinine for nephrotoxicity rates, followed by model-based, unsupervised clustering resolved trials into two distinct, significantly different (<it>p </it>< 0.0001) and homogeneous populations (<it>I</it><sup>2 </sup>= 0 and <it>p </it>> 0.5, for both). Cluster 1 studies (<it>n </it>= 18; 2445 patients) showed no benefit (relative risk (RR) = 0.87; 95% confidence interval (CI) 0.68–1.12, <it>p </it>= 0.28), while cluster 2 studies (<it>n </it>= 4; 301 patients) indicated that NAC was highly beneficial (RR = 0.15; 95% CI 0.07–0.33, <it>p </it>< 0.0001). Benefit in cluster 2 was unexpectedly associated with NAC-induced decreases in creatinine from baseline (<it>p </it>= 0.07). Cluster 2 studies were relatively early, small and of lower quality compared with cluster 1 studies (<it>p </it>= 0.01 for the three factors combined). Dialysis use across all studies (five control, eight treatment; <it>p </it>= 0.42) did not suggest that NAC is beneficial.</p> <p>Conclusion</p> <p>This meta-analysis does not support the efficacy of NAC to prevent CIN.</p
Estudo comparativo controlado com emprego de benznidazole, nifurtimox e placebo, na forma crônica da doença de Chagas, em uma área de campo com transmissão interrompida. I. Avaliação preliminar
Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study
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