457 research outputs found
Revisiting "New Cambridge": The three financial balances in a general stock-flow consistent applied modeling strategy
This paper argues that modified versions of the so-called 'New Cambridge' approach to macroeconomic modeling are both quite useful for modeling real capitalist economies in historical time and perfectly compatible with the 'vision' underlying modern Post-Keynesian stock-flow consistent macroeconomic models. As such, New Cambridge-type models appear to us as an important contribution to the tool kit available to applied macroeconomists in general and to heterodox applied macroeconomists in particular
WALO: ferramenta para gerenciamento de mídias sociais / WALO: social media management tool
A mídia social é uma ferramenta muito importante para as empresas, especialmente aquelas que dependem de estratégias de marketing para maior reconhecimento da marca. Além disso, as mídias sociais ajudam a enriquecer a experiência do cliente e reduzir as despesas de marketing. O gerenciamento de mídia social permite que as empresas obtenham informações que representam o sentimento geral do consumidor sobre sua marca ou seus produtos, de maneira rápida e segura. No entanto, esse gerenciamento não é uma tarefa fácil, pois a grande quantidade de mídias sociais existentes exige muito esforço dos profissionais para lidar com todas as informações que influenciam essas mídias sociais. Portanto, é identificada uma necessidade razoável na criação de uma ferramenta específica para gerenciar as mídias sociais de uma só vez. Neste artigo, propomos o WALO, uma nova ferramenta de código aberto que permite aos profissionais usar diferentes mídias sociais simultaneamente, fornecendo uma nova maneira para esses profissionais interagirem com seus clientes por meio de um chatbot.
The construction of early school leaving as a political concept under the lenses of sociology of education
Además de formar parte de las estadísticas, el abandono escolar temprano (ESL según sus siglas en inglés) es un concepto político que requiere reflexión y discusión. Este artículo se basa en un proyecto de investigación sobre el abandono escolar temprano en 9 países de la Unión Europea para centrar el problema portugués, donde el tema de la deserción escolar y su contexto social, económico y político toma dimensiones particularmente graves. Haciendo un análisis diacrónico entre 2000 y 2014, este artículo define y explica las características de tres subperiodos, vinculados a los diferentes modos de gobierno de la educación. Centrándose en particular en el periodo actual, empezando en 2011, este trabajo recoge diferentes perspectivas sobre el problema y analiza las políticas y condiciones que lo rodean. El objetivo es contribuir con una
mirada de la sociología de la educación a la comprensión de la construcción del abandono escolar temprano como concepto político y el análisis de las prácticas políticas para
confrontarlo, teniendo en cuenta los impactos de los cambios educativos en la equidad educativa y los derechos pedagógicos. Sostenemos que dada la actual tendencia a la segregación de algunos grupos dentro del sistema educativo y la prevalencia de la lógica competitiva en detrimento de la búsqueda de la inclusión social, que amenazan el logro de los derechos pedagógicos en particular para los grupos con mayor vulnerabilidad social, se acentúa la necesidad de medidas educativas de gran alcance que tengan en cuenta y den valor a los puntos de vista e intereses de los intervinientes en los diferentes niveles de fabricación del espacio educativo europeo.Para além de uma construção estatística, o abandono escolar precoce (ESL) é um conceito político que exige reflexão e questionamento. Este artigo baseia-se num projeto de pesquisa sobre ‘abandono escolar precoce’, em 9 países da União Europeia, e centra-se no caso português, onde o abandono da escola assume dimensões particularmente graves. Este artigo define e explicita as características de três sub períodos, entre 2000 e 2015, ligados a diferentes modos da governação da educação, focando-se, em particular, no período que decorre de 2011 até ao presente, relacionando com perspetivas de atores envolvidos. Pretende contribuir com um olhar da sociologia da educação para a compreensão da construção do ‘abandono escolar precoce’ como conceito político e para a análise de políticas para o confrontar, tendo em conta os impactos das mudanças educativas na equidade educacional e nos direitos pedagógicos. Argumentamos que
face à tendência atual para a segregação de alguns grupos no interior do sistema educativo e à prevalência da lógica de competitividade em detrimento da busca de inclusão social, que põem em risco a realização dos direitos pedagógicos particularmente para as pessoas de grupos com maior vulnerabilidade social, se acentua a necessidade de medidas educativas poderosas que tenham em conta e que atribuam valor às visões e interesses de atores distintos, nos diferentes níveis da fabricação do espaço Europeu de educação.Beyond the statistical construction, early school leaving (ESL) is a political concept that requires reflection and questioning. This article is based on a research project on early school leaving in 9 countries of the European Union to center the Portuguese problem, where the issue of early school leaving and its social economic and political context assumes particularly serious dimensions. The article defines and explains the features of three sub-periods, between 2000 and 2015, linked to different modes of education governance. Focusing in particular on the current
period, running from 2011, this work captures different perspectives on the problem and analyzes the policies and conditions that surround it. The goal is to contribute with the lenses of sociology of education to understand the construction of early school leaving as a political concept and to the analysis of political practices to confront it, while taking into account the impacts of educational changes in educational equity and the democratic pedagogic rights. We argue that the current trend to segregate some groups within the education system and the prevalence of the
logics of competitiveness to the detriment of the search for social inclusion, which threaten the achievement of pedagogic rights particularly for those groups with greater social vulnerability, gives evidence to the need for powerful educational measures that take into account and assign value to the views and interests of diverse actors at different levels of the fabrication of the European education space.Universidad de Granada. Departamento de Didáctica y Organización EscolarGrupo FORCE (HUM-386)Este trabajo está financiado (parcialmente) por Fondos Nacionales a través de la FCT–Fundación para la Ciencia y la Tecnología dentro del ámbito del proyecto estratégico del CIIE, con la referencia “PEst-OE/CED/UI0167/2014”
Land use and land cover mapping in detailed scale: A case study in santa rosa de Lima-SC
It is challenging to reconcile large scale data with the dynamic characteristics present in land use. Such dynamism requires data with a high repetition of sampling. An alternative is the integration of data of high spatial resolution and low temporal resolution, with that of high temporal resolution and low spatial resolution. The aim addressed in this article is related to the integration of aerial photographs and temporal series for land use and land cover mapping in high detail scale. We conducted a case study in Santa Rosa de Lima-SC. The main data used was the aerial survey that overlaid the state of Santa Catarina, executed in 2010/2011. The interpretation key included typical elements of photointerpretation (color, texture, size, shape), aiming to classify the land use and land cover classes. The mapping evaluation resulted in 75.6% global accuracy, ranging from 54% (Grassland and Wetlands) to 96% (Water Bodies and Rocks). Such results are considered satisfactory. The integration of high-resolution images with high temporal resolution data has enabled the discrimination between classes that present great difficulties of separability. Such discrimination is essential in the territorial management processes of Encosta da Serra and the municipality of Santa Rosa de Lima
Reinforcement Learning para treino do Pac-Man em Speedrun / Reinforcement Learning for Pac-Man Speedrun Training
Os algoritmos de Reinforcement Learning têm o objetivo de melhorar o comportamento do agente em um ambiente específico. Esses algoritmos se mostraram excelentes na melhoria da inteligência artificial em games de diversos gêneros. Nesse trabalho é usado o algoritmo Q-Learning do Reinforcement Learning aplicado no jogo Pac-Man, um dos jogos mais tradicionais que fomentam o desenvolvimento de novos algoritmos para a área de inteligência artificial. O objetivo principal é treinar o Pac-Man para escolher os melhores caminhos e assim terminar o jogo o mais rápido possível, de acordo com o modo de jogo speedrun. Os resultados obtidos por esse trabalho mostraram que foi possível fazer o Pac-Man ter bons resultados no modo speedrun
HIGH DOSE CARBOPLATIN, ETOPOSIDE, MELPHALAN and AUTOLOGOUS HEMATOPOIETIC STEM CELL RESCUE WITH for the TREATMENT of RELAPSED PEDIATRIC GERM CELL TUMORS
Inst Oncol Pediat, São Paulo, BrazilWeb of Scienc
Description of Genetic Variants in BRCA Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine
Abstract
Gynecologic cancers are among the leading causes of death worldwide, ovarian cancer being the one with the highest mortality rate. Olaparib is a targeted therapy used in patients presenting mutations in BRCA1 and BRCA2 genes. The aim of this study was to describe BRCA1 and BRCA2 gene variants in Mexican patients with ovarian cancer. Sequencing of BRCA1 and BRCA2 genes from tumors of 50 Mexican patients with ovarian cancer was made in a retrospective, non-randomized, and exploratory study. We found genetic variants in 48 of 50 cases. A total of 76 polymorphic variants were found in BRCA1, of which 50 (66%) had not been previously reported. Furthermore, 104 polymorphic variants were found in BRCA2, of which 63 (60%) had not been reported previously. Of these polymorphisms, 5/76 (6.6%) and 4/104 (3.8%) were classified as pathogenic in BRCA1 and BRCA2, respectively. We have described the genetic variants in BRCA1 and BRCA2 of tumors from Northeast Mexican patients with sporadic ovarian cancers. Our results showed that the use of genetic testing helps recognize patients that carry pathogenic variants which could be beneficial for personalized medicine treatments.
Keywords: BRCA; ovarian cancer; personalized therapy; sequencin
Enhancing Network Slicing Architectures with Machine Learning, Security, Sustainability and Experimental Networks Integration
Network Slicing (NS) is an essential technique extensively used in 5G
networks computing strategies, mobile edge computing, mobile cloud computing,
and verticals like the Internet of Vehicles and industrial IoT, among others.
NS is foreseen as one of the leading enablers for 6G futuristic and highly
demanding applications since it allows the optimization and customization of
scarce and disputed resources among dynamic, demanding clients with highly
distinct application requirements. Various standardization organizations, like
3GPP's proposal for new generation networks and state-of-the-art 5G/6G research
projects, are proposing new NS architectures. However, new NS architectures
have to deal with an extensive range of requirements that inherently result in
having NS architecture proposals typically fulfilling the needs of specific
sets of domains with commonalities. The Slicing Future Internet Infrastructures
(SFI2) architecture proposal explores the gap resulting from the diversity of
NS architectures target domains by proposing a new NS reference architecture
with a defined focus on integrating experimental networks and enhancing the NS
architecture with Machine Learning (ML) native optimizations, energy-efficient
slicing, and slicing-tailored security functionalities. The SFI2 architectural
main contribution includes the utilization of the slice-as-a-service paradigm
for end-to-end orchestration of resources across multi-domains and
multi-technology experimental networks. In addition, the SFI2 reference
architecture instantiations will enhance the multi-domain and multi-technology
integrated experimental network deployment with native ML optimization,
energy-efficient aware slicing, and slicing-tailored security functionalities
for the practical domain.Comment: 10 pages, 11 figure
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