Bayesian Inference Analysis of Unmodelled Gravitational-Wave Transients

We report the results of an in-depth analysis of the parameter estimation capabilities of BayesWave, an algorithm for the reconstruction of gravitational-wave signals without reference to a specific signal model. Using binary black hole signals, we compare BayesWave's performance to the theoretical best achievable performance in three key areas: sky localisation accuracy, signal/noise discrimination, and waveform reconstruction accuracy. BayesWave is most effective for signals that have very compact time-frequency representations. For binaries, where the signal time-frequency volume decreases with mass, we find that BayesWave's performance reaches or approaches theoretical optimal limits for system masses above approximately 50 M_sun. For such systems BayesWave is able to localise the source on the sky as well as templated Bayesian analyses that rely on a precise signal model, and it is better than timing-only triangulation in all cases. We also show that the discrimination of signals against glitches and noise closely follow analytical predictions, and that only a small fraction of signals are discarded as glitches at a false alarm rate of 1/100 y. Finally, the match between BayesWave- reconstructed signals and injected signals is broadly consistent with first-principles estimates of the maximum possible accuracy, peaking at about 0.95 for high mass systems and decreasing for lower-mass systems. These results demonstrate the potential of unmodelled signal reconstruction techniques for gravitational-wave astronomy.Comment: 10 pages, 7 figure

Proyecto de inversión para la elaboración y comercialización de un dulce a base de frutas no tradicionales

En nuestra vida, la experiencia juega un papel primordial como medio de aprendizaje: Aprendemos a comer, a caminar, a comunicarnos mediante ensayo y error, cuando realizamos un acto y vemos la consecuencia de ello. Nuestros antecedentes serian eso que llaman intuición, olfato o corazonada, jugando un papel importante esas ganas de realizarnos como emprendedores e innovadores, escogiendo este producto; ya que podríamos decir que lo conocemos y sabemos su desenvolvimiento en el mercado, escogido no solo por ser alimenticio, sino por llevar a cabo diversas campañas de salud y crear una cultura de alimentarnos sanamente, no teniendo la experiencia en este tipo de productos, pero con el objetivo de alcanzarlo mediante ensayo y éxito. Como algunos desconocen a diferencia de las hortalizas, las frutas obedecen en su clasificación tanto a criterios botánicos como culturales, para conformar un grupo de especies generalmente arbóreas o arbustivas cuyos frutos se consumen frescos, procesados o preparados en jugos o mezclas con otros productos. A semejanza de las hortalizas su cultivo es intensivo en mano de obra de tal forma que cada planta recibe cuidados individuales a lo largo de su ciclo productivo. El fruto como tal es el ovario fecundado o no, desarrollado y consumido en distintos grados de maduración y generalmente jugosos, dulces y acidulados. Las frutas tropicales han comenzado recientemente a proliferar con una gran variedad en los mercados occidentales siendo hasta ahora desconocidas para muchos. Estas frutas exóticas en algunos casos son completamente naturales y ecológicas así no estén certificadas debido a su método de cultivo. Frutas de Colombia, Puerto Rico, Malasia, Brasil, El Salvador o frutas del Ecuador entre otros muchos países están llevando hasta los puntos de venta de frutas nuevos sabores, colores, aromas y formas de disfrutar de estos tipos de frutas tropicales. Generalmente estas frutas exóticas llegan hasta los consumidores como fruta fresca, pulpa de frutas o frutas deshidratadas. Aun existe mucho desconocimiento en cuanto a la manera de consumir muchas de estas frutas tropicales lo cual puede llevar a su rechazo. Debido al gran consumo de frutas que existe en nuestro país nos vimos inspirados a darle un valor agregado por lo cual nace la idea de crear dulces de las más exquisitas y exóticas frutas. Nuestra empresa EXOTIC FRUITS COMPANY LTD., ha realizado investigaciones acerca de estas frutas denominadas exóticas y ha determinado que el suculento sabor de la pulpa hace que estas frutas agraden a la mayoría de personas que lo prueban. Sus propiedades nutritivas permiten que puedan ser consumidas por personas de todas las edades. Nuestra compañía se dedicara especialmente a la elaboración de dulce de frutas no tradicionales; las frutas con las cuales se realiza dicho dulce son: la grosella, el níspero, el taxo, uvilla y kiwi. Este dulce de fruta no tradicional es un producto nuevo en el mercado, pero estamos seguros que tendrá una gran aceptación en la ciudad de Guayaquil, a nivel nacional y posteriormente a nivel internacional

GLADE: A galaxy catalogue for multimessenger searches in the advanced gravitational-wave detector era

We introduce a value-added full-sky catalogue of galaxies, named as Galaxy List for the Advanced Detector Era, or GLADE. The purpose of this catalogue is to (i) help identifications of host candidates for gravitational-wave events, (ii) support target selections for electromagnetic follow-up observations of gravitational-wave candidates, (iii) provide input data on the matter distribution of the local Universe for astrophysical or cosmological simulations, and (iv) help identifications of host candidates for poorly localized electromagnetic transients, such as gamma-ray bursts observed with the InterPlanetary Network. Both being potential hosts of astrophysical sources of gravitational waves, GLADE includes inactive and active galaxies as well. GLADE was constructed by cross-matching and combining data from five separate (but not independent) astronomical catalogues: GWGC, 2MPZ, 2MASS XSC, HyperLEDA, and SDSS-DR12Q. GLADE is complete up to dL=37+3−4Mpc in terms of the cumulative B-band luminosity of galaxies within luminosity distance dL, and contains all of the brightest galaxies giving half of the total B-band luminosity up to dL=91Mpc. As B-band luminosity is expected to be a tracer of binary neutron star mergers (currently the prime targets of joint GW+EM detections), our completeness measures can be used as estimations of completeness for containing all binary neutron star merger hosts in the local Universe

Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids

© 2012 Matyášek et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Endocrinology: Nuclear maturity and oocyte morphology after stimulation with highly purified follicle stimulating hormone compared to human menopausal gonadotrophin

Several studies have shown that high concentrations of luteinizing hormone (LH) in the follicular phase of stimulation can have a negative effect on oocyte quality, pregnancy rate and incidence of miscarriage. The aim of the present study was to examine the effects of highly purified follicle stimulating hormone (FSH HP) on ovarian stimulation and particularly on nuclear maturity and morphological appearance of the oocyte in intracytoplasmic sperm injection (ICSI) therapy and to compare the results with human menopausal gonadotrophin (HMG) stimulation. For this purpose, 50 patients for ICSI (HMG: 30; FSH HP: 20) and 26 patients for in-vitro fertilization (TVF; HMG: 14, FSH HP: 12) were stimulated with either HMG of FSH HP using a short-term protocol. Patients were divided into the two groups according to the first letter of their family name. No differences were observed among the groups in relation to patient age, duration of stimulation, number of aspirated oocytes or maturity of the oocyte-cumulus complex. After removal of the cumulus-corona cells in the ICSI oocytes, a significantly higher proportion of oocytes in the FSH HP group were nuclear mature (metaphase II) than in the HMG group (FSH HP: 88.8%, HMG: 80.6%; P = 0.009). Furthermore, in the FSH HP group, significantly fewer oocytes with dark cytoplasm were observed (FSH HP: 14.4%, HMG: 22.4%; P = 0.02). Fertilization, cleavage and pregnancy rates (FSH HP 38%, HMG: 34% per retrieval) were comparable in both groups. Based on the results obtained, it can be concluded that the short-term FSH HP treatment protocol synchronizes oocyte maturation better than comparable stimulation with HM

Fertilization and early embryology: The chromosomal complements of multipronuclear human zygotes resulting from intracytoplasmic sperm injection

Implementation of intracytoplasmic sperm injection (ICSI) in human in-vitro fertilization (IVF) has highlighted the need for information about the risk of nuclear spindle damage caused by this procedure. For this purpose we studied the final products of oocyte meiosis at the first cleavage division of multipronuclear zygotes arising after ICSI, and compared the results with abnormally fertilized oocytes after conventional in-vitro insemination. Of 37 successfully analysed tripronuclear zygotes, 18 had three individual metaphases. Abnormal complements of 11 zygotes in this group indicated that non-disjunction occurred predominantly at the second meiotic division of the oocytes. Nine of the 37 tripronuclear zygotes exhibited two individual metaphases. Seven were abnormal and there were some indications that non-disjunction took place during oocyte meiosis. Of the 37 tripronuclear zygotes, 10 had a single metaphase and three showed an aneuploid number of chromosomes. The overall rate of aneuploidy among tripronuclear microinjected zygotes was 56.7%. In addition, seven zygotes with more than three pronuclei arising after ICSI displayed severely depleted chromosome complements. The incidence of non-disjunction in oocytes fertilized by conventional in-vitro insemination was significantly lower (20.0%, P < 0.01), since only four zygotes had an aneuploid number of chromosomes. Our findings suggest that ICSI might interfere with regular chromosome segregation at the second meiotic division of the oocyte

Reingeniería de los procesos de distribución de la mercadería entregada a los clientes de la empresa unigranca s. a.

El proyecto que se realiza se basa en el estudio de la situación administrativa y logística de la empresa UNIGRANCA S.A., que está domiciliada en Guayaquil, en Gómez Rendón 3900 y la 16, la cual maneja un modelo de negocio basado en la comercialización de artículos para el hogar a través de catálogos, ofreciendo facilidades de pagos semanales a sus clientes que son sus representantes de venta. El problema principal que presenta la empresa es la falta de control del inventario, dado por la carencia de un eficiente sistema logístico que permita llevar una organización de los pedidos y del stock de las mercancías para así abastecerse en el tiempo pactado, además de no facilitar el aprovechamiento del espacio. Algunas de las acciones que se tomarán para su ejecución son; organizar al personal quien será el responsable del buen estado de la mercancía, así como también del pedido a tiempo de los productos que se requieran, además del control y distribución eficaz a los diferentes puntos de entrega. También se ha realizado un estudio financiero para establecer la rentabilidad del proyecto

Andrology: Effects of nitric oxide on human spermatozoa: evidence that nitric oxide decreases sperm motility and induces sperm toxicity

Endogenous nitric oxide (NO) is an important functional mediator in several physiological systems, including the reproductive system. However, when generated in excessive amounts for long periods, mainly during immunological reactions, NO is cytotoxic and cytostatic for invading microbes, as well as for the cells generating it and the tissues present around it. Since infertility associated with urogenital tract infection in males and females is also accompanied by reduced sperm motility and viability, it is possible that reduced fertility in these patients is due to NO-induced sperm toxicity. We therefore evaluated the direct effects of NO, chemically derived from S-nitroso-N-acetylpenicillamine (SNAP, 0.012-0.6 mM) and sodium nitroprusside (SNP, 0.25-2.5 mM), on the motility and viability of human spermatozoa. Furthermore, we tested whether inhibition of NO synthesis prevents sperm motility and viability by incubating washed total cells present in the semen (spermatozoa, round cells) with N-nitro-L-arginine-methyl-ester (L-NAME), a NO synthesis inhibitor. Treatment of purified spermatozoa with SNAP or SNP decreased forward progressive sperm motility and straight line velocity, and also increased the percentage of immotile spermatozoa in a concentration-dependent manner. Furthermore, the percentage of immotile spermatozoa positively correlated with the percentage of dead spermatozoa. In contrast to freshly prepared SNAP, SNAP preincubated for 48 h had no effect on the motility and viability of the spermatozoa. Furthermore, as compared to untreated controls, a significantly higher percentage of forward progressive sperm motility as well as viability (P < 0.05) was maintained in washed semen incubated with L-NAME (0.15 mM). Seminal plasma concentrations of nitrite-nitrate (stabile metabolites of NO/106 spermatozoa correlated positively (P < 0.05) with the percentage of immotile spermatozoa. Our results suggest that NO can cause sperm toxicity as well as inhibit sperm motility. In conclusion, excessive NO synthesis in response to infection and inflammation could be an important factor contributing to functional change of the spermatozoa, leading to their dysfunction and to infertilit

Diagnóstico clínico periodontal en pacientes con diabetes mellitus tipo 1 y tipo 2 atendidos en las Fundaciones DONUM y la Casa de la Diabetes de la ciudad de Cuenca en el periodo: enero a julio de 2015

La diabetes constituye un grupo de desórdenes caracterizado por un estado de hiperglicemia que afecta el metabolismo de carbohidratos, grasas y proteínas, debido a la secreción y/o acción anormal de la insulina. La periodontitis es una enfermedad inflamatoria de los tejidos de soporte de los dientes; siendo las dos patologías de alta prevalencia a nivel mundial. Ha sido demostrado que la diabetes y la enfermedad periodontal presentan una relación bidireccional. Se realizó el diagnóstico periodontal y examen de hemoglobina glicosilada en 101 pacientes diabéticos Tipo 1 y tipo 2. OBJETIVOS: Determinar el diagnóstico clínico periodontal en pacientes con diabetes Tipo 1 y Tipo 2 y relacionarlo con el grado de control metabólico. RESULTADOS: Se encontró que 14,9% de los pacientes diabéticos presentaron gingivitis y 85.1% periodontitis, ningún paciente presento salud periodontal y se encontró que hay una diferencia estadísticamente significativa entre mal control metabólico y enfermedad periodontal p=0.016. CONCLUSIÓN: Ante un mal control metabólico, la severidad de la enfermedad periodontal es peor, por lo que se debe mejorar la interacción médico odontólogo, para brindar una mejor calidad de vida a los pacientes diabéticosDiabetes constitutes a group of disorders characterized by a state of hyperglycemia that affects the metabolism of carbohydrates, fats and proteins, due to the secretion and / or abnormal insulin action. Periodontitis is an inflammatory disease of the supportive tissues of the teeth; Being these two pathologies of high prevalence worldwide. It has been demonstrated that diabetes and periodontal disease have a bidirectional relation. Periodontal diagnosis and glycosylated hemoglobin test were realized in 101 patients with diabetes type 1 and type 2. OBJECTIVE: The objectives of this study were to determine the periodontal clinical diagnosis in patients with Diabetes Type 1 and Type 2 and relate it to the degree of metabolic control. RESULTS: It was found that 14.9% of diabetic patients presented gingivitis and 85.1% presented periodontitis, no patient had periodontal health and it was found a statistically significant difference between poor metabolic control and periodontal disease p = 0.016. CONCLUSION: A worse metabolic control, worse is the severity of periodontal disease, for which the interaction dentist-doctor should be strengthened to provide a better quality of life for diabetic patientsOdontólogoCuenc

Diseño e implementación de una metodología para un manual de procesos y procedimientos aplicado al área contable-financiera de la empresa Bluecard Ecuador S.A. en el distrito metropolitano de Quito

At present manual processes and financial accounting procedures is an important support tool in any company, through this guide can strengthen and improve internal control, manual assist internal users get detailed information ordered, systematic and comprehensive process, procedures, policies and responsibilities of the activities and functions that are developed within each department. An efficient and effective development of processes and procedures contablesfinancieros is a pillar and fundamental tool for good management of efficient human, technological and financial resources.En la actualidad un manual de procesos y procedimientos contables financieros es un instrumento de apoyo importante dentro de toda empresa, a través de esta guía se puede fortalecer y mejorar el control interno, los manuales ayudan a los usuarios internos a obtener información detallada, ordenada, sistemática e integral de los procesos, procedimientos, políticas y responsabilidades de las actividades y funciones que se desarrollan dentro de cada departamento. Un desarrollo eficiente y eficaz de los procesos y procedimientos contablesfinancieros es un pilar y herramienta fundamental para un buen manejo de recursos humanos, tecnológicos y financieros eficientes