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The influence of large predators on the feeding ecology of two African mesocarnivores: the black-backed jackal and the brown hyaena
Interactions between apex and mesopredators and their impacts on prey populations have been well documented, while the influence of apex predators such as lions on carrion availability and the subsequent impacts at lower trophic levels are not fully understood. Here we assess dietary overlap between two sympatric carnivores (brown hyaena, Parahyaena brunnea, and black-backed jackal, Canis mesomelas) in neighbouring reserves with and without apex predators (lions, Panthera leo,and wild dog, Lycaon pictus). We investigate whether apex predators facilitate niche partitioning between mesocarnivores by creating additional scavenging opportunities through predatory activity. We found that brown hyaena density was higher in the area with apex predators, while black-backed jackal density was higher in the area without apex predators. Black-backed jackal scats contained broadly similar dietary items at both sites, while large mammal remains occurred significantly more frequently in brown hyaena scats collected inthe presence of apex predators. In the absence of apex predators there was a markedly higher degree of overlap between brown hyaena and jackal diets, suggesting increased levels of inter-specific competition. Our results suggest that apex predators potentially reduce levels of inter-specific competition for food between mesocarnivores by providing additional scavenging opportunities for specialist scavengers such as brown hyaena
Neutrino mass constraint from CMB and its degeneracy with other cosmological parameters
We show that the cosmic microwave background (CMB) data of WMAP can give
subelectronvolt limit on the neutrino mass: m_nu < 0.63 eV (95% CL). We also
investigate its degeneracy with other cosmological parameters. In particular,
we show the Hubble constant derived from the WMAP data decreases considerably
when the neutrino mass is a few times 0.1 eV.Comment: 3 pages, 2 figures, prepared for the TAUP2007 Proceeding
Conceptual model of sport-specific classification for para-athletes with intellectual impairment
The present paper describes the conceptual basis of evidence-based classification of para-athletes with intellectual impairment (II). An extensive description of the theoretical and conceptual foundation of the system as currently conceived is provided, as are examples of its applications in the three sports included in the Paralympic programme for II-athletes in 2020 (i.e., athletics, swimming and table tennis). Evidence based classification for II-athletes is driven by two central questions: i. How can intellectual impairment be substantiated in a valid and reliable way, and ii. Does intellectual impairment limit optimal sport proficiency? Evolution of the system and current best practice for addressing these questions are described, and suggestions for future research and development are provided. Challenges of understanding and assessing a complex (multifaceted and intersectional) impairment in the context of sport also are considered
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors
Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV. As attenuated tumour-selective oncolytic vaccinia viruses (VV) are already undergoing clinical evaluation, the goal of this study is to determine whether HDI can also enhance the potency of these poxviruses in infection-resistant cancer cell lines. Multiple HDIs were tested and Trichostatin A (TSA) was found to potently enhance the spread and replication of a tumour selective vaccinia virus in several infection-resistant cancer cell lines. TSA significantly decreased the number of lung metastases in a syngeneic B16F10LacZ lung metastasis model yet did not increase the replication of vaccinia in normal tissues. The combination of TSA and VV increased survival of mice harbouring human HCT116 colon tumour xenografts as compared to mice treated with either agent alone. We conclude that TSA can selectively and effectively enhance the replication and spread of oncolytic vaccinia virus in cancer cells. © 2010 MacTavish et al
Cosmic Microwave Background Polarization
Cosmic microwave background (CMB) anisotropy is our richest source of
cosmological information; the standard cosmological model was largely
established thanks to study of the temperature anisotropies. By the end of the
decade, the Planck satellite will close this important chapter and move us
deeper into the new frontier of polarization measurements. Numerous
ground--based and balloon--borne experiments are already forging into this new
territory. Besides providing new and independent information on the primordial
density perturbations and cosmological parameters, polarization measurements
offer the potential to detect primordial gravity waves, constrain dark energy
and measure the neutrino mass scale. A vigorous experimental program is
underway worldwide and heading towards a new satellite mission dedicated to CMB
polarization.Comment: Review given at TAUP 2005; References added; Additional reference
Carbon amendment stimulates benthic nitrogen cycling during the bioremediation of particulate aquaculture waste
The treatment of organic wastes remains one of the key sustainability challenges facing the growing global aquaculture industry. Bioremediation systems based on coupled bioturbation-microbial processing offer a promising route for waste management. We present, for the first time, a combined biogeochemical-molecular analysis of the short-term performance of one such system that is designed to receive nitrogen-rich particulate aquaculture wastes. Using sea cucumbers (Holothuria scabra) as a model bioturbator we provide evidence that adjusting the waste CgN from 5g1 to 20g1 promoted a shift in nitrogen cycling pathways towards the dissimilatory nitrate reduction to ammonium (DNRA), resulting in net NH4+ efflux from the sediment. The carbon amended treatment exhibited an overall net N2 uptake, whereas the control receiving only aquaculture waste exhibited net N2 production, suggesting that carbon supplementation enhanced nitrogen fixation. The higher NH4+ efflux and N2 uptake was further supported by meta-genome predictions that indicate that organic-carbon addition stimulated DNRA over denitrification. These findings indicate that carbon addition may potentially result in greater retention of nitrogen within the system; however, longer-term trials are necessary to determine whether this nitrogen retention is translated into improved sea cucumber biomass yields. Whether this truly constitutes a remediation process is open for debate as there remains the risk that any increased nitrogen retention may be temporary, with any subsequent release potentially raising the eutrophication risk. Longer and larger-scale trials are required before this approach may be validated with the complexities of the in-system nitrogen cycle being fully understood
Enhancing the tensor-to-scalar ratio in simple inflation
We show that in theories with a nontrivial kinetic term the contribution of
the gravitational waves to the CMB fluctuations can be substantially larger
than that is naively expected in simple inflationary models. This increase of
the tensor-to-scalar perturbation ratio leads to a larger B-component of the
CMB polarization, thus making the prospects for future detection much more
promising. The other important consequence of the considered model is a higher
energy scale of inflation and hence higher reheating temperature compared to a
simple inflation.Comment: 9 pages, 1 figure and references are added, discussion is slightly
extended, published versio
`Standard' Cosmological model & beyond with CMB
Observational Cosmology has indeed made very rapid progress in the past
decade. The ability to quantify the universe has largely improved due to
observational constraints coming from structure formation Measurements of CMB
anisotropy and, more recently, polarization have played a very important role.
Besides precise determination of various parameters of the `standard'
cosmological model, observations have also established some important basic
tenets that underlie models of cosmology and structure formation in the
universe -- `acausally' correlated initial perturbations in a flat,
statistically isotropic universe, adiabatic nature of primordial density
perturbations. These are consistent with the expectation of the paradigm of
inflation and the generic prediction of the simplest realization of
inflationary scenario in the early universe. Further, gravitational instability
is the established mechanism for structure formation from these initial
perturbations. The signature of primordial perturbations observed as the CMB
anisotropy and polarization is the most compelling evidence for new, possibly
fundamental, physics in the early universe. The community is now looking beyond
the estimation of parameters of a working `standard' model of cosmology for
subtle, characteristic signatures from early universe physics.Comment: 16 pages, 6 figures, Plenary talk, Proc. of GR-19, Mexico City,
Mexico (Jul 5-9, 2010). To appear in a special issue in Class. Q. Gra
Probing for cosmological parameters with LAMOST measurement
In this paper we study the sensitivity of the Large Sky Area Multi-Object
Fiber Spectroscopic Telescope (LAMOST) project to the determination of
cosmological parameters, employing the Monte Carlo Markov Chains (MCMC) method.
For comparison, we first analyze the constraints on cosmological parameters
from current observational data, including WMAP, SDSS and SN Ia. We then
simulate the 3D matter power spectrum data expected from LAMOST, together with
the simulated CMB data for PLANCK and the SN Ia from 5-year Supernovae Legacy
Survey (SNLS). With the simulated data, we investigate the future improvement
on cosmological parameter constraints, emphasizing the role of LAMOST. Our
results show the potential of LAMOST in probing for the cosmological
parameters, especially in constraining the equation-of-state (EoS) of the dark
energy and the neutrino mass.Comment: 7 pages and 3 figures. Replaced with version accepted for publication
in JCA
Fast and precise map-making for massively multi-detector CMB experiments
Future cosmic microwave background (CMB) polarisation experiments aim to
measure an unprecedentedly small signal - the primordial gravity wave component
of the polarisation field B-mode. To achieve this, they will analyse huge
datasets, involving years worth of time-ordered data (TOD) from massively
multi-detector focal planes. This creates the need for fast and precise methods
to complement the M-L approach in analysis pipelines. In this paper, we
investigate fast map-making methods as applied to long duration, massively
multi-detector, ground-based experiments, in the context of the search for
B-modes. We focus on two alternative map-making approaches: destriping and TOD
filtering, comparing their performance on simulated multi-detector polarisation
data. We have written an optimised, parallel destriping code, the DEStriping
CARTographer DESCART, that is generalised for massive focal planes, including
the potential effect of cross-correlated TOD 1/f noise. We also determine the
scaling of computing time for destriping as applied to a simulated full-season
data-set for a realistic experiment. We find that destriping can out-perform
filtering in estimating both the large-scale E and B-mode angular power
spectra. In particular, filtering can produce significant spurious B-mode power
via EB mixing. Whilst this can be removed, it contributes to the variance of
B-mode bandpower estimates at scales near the primordial B-mode peak. For the
experimental configuration we simulate, this has an effect on the possible
detection significance for primordial B-modes. Destriping is a viable
alternative fast method to the full M-L approach that does not cause the
problems associated with filtering, and is flexible enough to fit into both M-L
and Monte-Carlo pseudo-Cl pipelines.Comment: 16 pages, 14 figures. MNRAS accepted. Typos corrected and computing
time/memory requirement orders-of-magnitude numbers in section 4 replaced by
precise number
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