Pain-related Somato Sensory Evoked Potentials: A potential new tool to improve the prognostic prediction of coma after cardiac arrest

INTRODUCTION: Early prediction of a good outcome in comatose patients after cardiac arrest still remains an unsolved problem. The main aim of the present study was to examine the accuracy of middle-latency SSEP triggered by a painful electrical stimulation on median nerves to predict a favorable outcome. METHODS: No- and low-flow times, pupillary reflex, Glasgow motor score and biochemical data were evaluated at ICU admission. The following were considered within 72 h of cardiac arrest: highest creatinine value, hyperthermia occurrence, EEG, SSEP at low- (10 mA) and high-intensity (50 mA) stimulation, and blood pressure reactivity to 50 mA. Intensive care treatments were also considered. Data were compared to survival, consciousness recovery and 6-month CPC (Cerebral Performance Category). RESULTS: Pupillary reflex and EEG were statistically significant in predicting survival; the absence of blood pressure reactivity seems to predict brain death within 7 days of cardiac arrest. Middle- and short-latency SSEP were statistically significant in predicting consciousness recovery, and middle-latency SSEP was statistically significant in predicting 6-month CPC outcome. The prognostic capability of 50 mA middle-latency-SSEP was demonstrated to occur earlier than that of EEG reactivity. CONCLUSIONS: Neurophysiological evaluation constitutes the key to early information about the neurological prognostication of postanoxic coma. In particular, the presence of 50 mA middle-latency SSEP seems to be an early and reliable predictor of good neurological outcome, and its absence constitutes a marker of poor prognosis. Moreover, the absence 50 mA blood pressure reactivity seems to identify patients evolving towards the brain death

Netflix and Chilling: Binge-Watching Behaviors and the Cultivation Effects of Horror Television Shows.

M.A. Thesis. University of Hawaiʻi at Mānoa 2018

Timing of the magmatism of the paleo-Pacific border of Gondwana: U-Pb geochronology of Late Paleozoic to Early Mesozoic igneous rocks of the north Chilean Andes between 20° and 31°S

Indexación: Web of Science; ScieloABSTRACT. U-Pb zircon geochronological data provide record of about 130 Ma of igneous activity in the Andes of northern Chile, which extended episodically from the latest Early Carboniferous to Early Jurassic (328-194 Ma). The overall U-Pb data show that volcanism and plutonism were essentially synchronous and major episodes of igneous activity developed during the Late Carboniferous to Mid-Permian (310 to 260 Ma) and from Late Permian to Late Triassic (255-205 Ma), with less prominent episodes in the mid-Carboniferous (330 to 320 Ma), and Early Jurassic (200-190 Ma). Thus, from the Carboniferous to the Early Triassic dominantly silicic magmatism developed along the Chilean segment of the southwestern border of Gondwana supercontinent. Further magmatism developed during the Mid-Late Triassic (250-194 Ma) was bimodal and synchronous with rift-related, continental and/or marine sedimentary strata related to the early stages of break-up of Gondwana. Most of the silicic volcanic rocks of the Precordillera and Domeyko Cordillera of northern Chile (21°30' to 25°30'S) are older than the silicic rocks assigned to the Choiyoi succession in Argentina, being instead equivalent in age to Carboniferous to Early Permian marine sedimentary sequences present in the eastern Argentinean foreland. On the other hand, silicic volcanic successions exposed in the easternmost part of northern Chile are equivalent in age to the Choiyoi succession of the San Rafael Block of Argentina. An eastward expansion or migration of the volcanism during the Mid-Permian to Early Triassic is inferred, interpretation that is consistent with expansion of the volcanism at that time in Argentina. The timing of the Late Paleozoic to Early Jurassic magmatism is coincident with that of the Andes of Perú and of western Argentina according to the available U-Pb data, revealing a rather consistent evolution in time of the magmatism along the southwestern, paleo-Pacific border of Gondwana. Keywords: Geochronology, U-Pb, Andes, Gondwana, Choiyoi, Paleozoic, Carboniferous, Triassic. RESUMEN. Los datos de U-Pb en circón registran aproximadamente 130 Ma de actividad ígnea en los Andes del norte de Chile, la que se extendió episódicamente desde el Carbonífero temprano hasta el Jurásico temprano (328-194 Ma). Los datos globales de U-Pb indican que el volcanismo y plutonismo fueron esencialmente sincrónicos con episodios mayores desde el Carbonífero tardío al Pérmico Medio (310-260 Ma) y durante el Pérmico Tardío a Triásico Tardío (255-205 Ma) y episodios menos prominentes durante el Carbonífero medio (330-320 Ma) y el Jurásico Temprano (200-190 Ma). Desde el Carbonífero hasta el Triásico Temprano se desarrolló magmatismo predominantemente félsico a lo largo del borde suroccidental del supercontinente de Gondwana, mientras que durante el Triásico medio a tardío (250-194 Ma) se desarrolló magmatismo bimodal sincrónico con estratos sedimentarios continentales y/o marinos relacionados con extensión (rift), durante las etapas tempranas de la desintegración de Gondwana. La mayor parte de las rocas volcánicas silíceas de la precordillera y la cordillera de Domeyko en el norte de Chile (21°30' a 25°30'S) son más antiguas que las rocas silíceas asignadas a la sucesión Choiyoi en Argentina, y son, en cambio, equivalentes en edad con las secuencias sedimentarias marinas del Carbonífero al Pérmico temprano presentes en el antepaís argentino al oriente. Por otra parte, las sucesiones volcánicas félsicas expuestas en la parte más oriental del norte de Chile, de la cordillera de Domeyko y de la cordillera Frontal al sur de 25°S son equivalentes en edad a la sucesión Choiyoi de Argentina. Se infiere una migración o expansión del volcanismo hacia el este durante el Pérmico Medio a Triásico Temprano, interpretación que es consistente con la expansión del volcanismo en Argentina durante ese período. La temporalidad del magmatismo del Paleozoico tardío a Mesozoico temprano es coincidente con la de los Andes de Perú y del oeste de Argentina, de acuerdo a los datos U-Pb disponibles, lo que revela una evolución temporal del magmatismo concordante a lo largo del borde suroeste del Gondwana. Palabras clave: Geocronología, U-Pb, Andes, Gondwana, Choiyoi, Paleozoico, Carbonífero, Triásico

Book Review: Vistas comerciales y culturales

Rview of Cahill, Danielle and Sandra de los Rios. Vistas Comerciales Y Culturales. Boston, MA: Heinle and Heinle, 2002. ISBN 0-03-031606-5. 347 pp

CAFTA y medio ambiente : análisis y lineamientos de reformas para enfrentar las nuevas reglas del juego establecidas por el tratado comercial en materia ambiental

Este libre se dirige a los lectores no especializados deseosos de entender el significado de los textos del Capítulo ambiental, Acuerdo de Cooperación ambiental y Solución de Controversias del Tratado de Libre Comercio entre Centroamérica, República Dominicana y Estados Unidos (CAFTA, por sus siglas en inglés), y las potenciales implicaciones que se derivan de los mismos. Las recomendaciones apuntan a mejorar las condiciones internas de El Salvador y región centroamericana, posibilitando una mejor administración del tratado en materia ambiental, partiendo de la premisa que el mismo contiene disposiciones que pueden causar impactos positivos o negativos en el marco jurídico e institucional ambiental

A Remark on Soliton Equation of Mean Curvature Flow

In this short note, we consider self-similar immersions $F: \mathbb{R}^n \to \mathbb{R}^{n+k}$ of the Graphic Mean Curvature Flow of higher co-dimension. We show that the following is true: Let $F(x) = (x,f(x)), x \in \mathbb{R}^{n}$ be a graph solution to the soliton equation $$\bar{H}(x) + F^{\bot}(x) = 0.$$ Assume $\sup_{\mathbb{R}^{n}}|Df(x)| \le C_{0} < + \infty$. Then there exists a unique smooth function $f_{\infty}: \mathbb{R}^{n}\to \mathbb{R}^k$ such that $$f_{\infty}(x) = \lim_{\lambda \to \infty}f_{\lambda}(x)$$ and $$f_{\infty}(r x)=r f_{\infty}(x)$$ for any real number $r\not= 0$, where $$f_{\lambda}(x) = \lambda^{-1}f(\lambda x).$$Comment: 6 page

FVF-Based Low-Dropout Voltage Regulator with Fast Charging/Discharging Paths for Fast Line and Load Regulation

A new internally compensated low drop-out voltage regulator based on the cascoded flipped voltage follower is presented in this paper. Adaptive biasing current and fast charging/discharging paths have been added to rapidly charge and discharge the parasitic capacitance of the pass transistor gate, thus improving the transient response. The proposed regulator was designed with standard 65-nm CMOS technology. Measurements show load and line regulations of 433.80 μV/mA and 5.61 mV/V, respectively. Furthermore, the output voltage spikes are kept under 76 mV for 0.1 mA to 100 mA load variations and 0.9 V to 1.2 V line variations with rise and fall times of 1 μs. The total current consumption is 17.88 μA (for a 0.9 V supply voltage).Ministerio de Economía y Competitividad TEC2015-71072-C3-3-RConsejería de Economía, Innovación y Ciencia. Junta de Andalucía P12-TIC-186