Constraints on the hosts of UHECR accelerators

Interactions of ultrahigh energy cosmic rays in the surroundings of their accelerators can naturally explain the observed spectrum and composition of UHECRs, including the abundance of protons below the ankle. We show that astrophysical properties of the UHECR source environment such as the temperature, size, and magnetic field can be constrained by UHECR and neutrino data. Applying this to candidate sources with a simple structure shows that starburst galaxies are consistent with these constraints, but galaxy clusters may be in tension with them. For multi-component systems like AGNs and GRBs the results are indicative but customized analysis is needed for definitive conclusions

Constraining the origin of UHECRs and astrophysical neutrinos

We explore the possibility of a common origin of ultrahigh energy cosmic rays (UHECRs) and astrophysical neutrinos and further constrain sources which are consistent with this possibility. We show that the common origin hypothesis can be satisfied for the Sibyll2.3c hadronic interaction model but is difficult to accommodate for EPOS-LHC, showing that multimessenger analyses have the power to also constrain hadronic physics beyond LHC energies. We constrain properties of UHECR source environments (and potentially astrophysical neutrino sources), including their photon temperature, gas density, size, magnetic field strength and coherence length, using UHECR and neutrino spectra and composition. Our analysis represents a new type of information on UHECR sources, independent of the mechanism responsible for the UHECR acceleration

Inserting professionals and professional organizations in studies of wrongdoing : the nature, antecedents and consequences of professional misconduct

Professional misconduct has become seemingly ubiquitous in recent decades. However, to date there has been little sustained effort to theorize the phenomenon of professional misconduct, how this relates to professional organizations, and how this may contribute to broader patterns of corruption and wrongdoing. In response to this gap, in this contribution we discuss the theoretical and empirical implications of analyses that focus on the nature, antecedents and consequences of professional misconduct. In particular, we discuss how the nature of professional misconduct can be quite variegated and nuanced, how boundaries between and within professions can be either too weak or too strong and lead to professional misconduct, and how the consequences of professional misconduct can be less straightforward than normally assumed. We also illuminate how some important questions about professional misconduct are still pending, including: how we define its different organizational forms; how it is instigated by the changing nature of professional boundaries; and how its consequences are responded to in professional organizations and society more widely

Changes in anthropometric, biochemical, hematological, hormonal and cardiac markers in a group of late-adult amateur cyclist, afet continuous and prolonged exercise on an uncontrolled diet

Abstract: Purpose: to describe and compare the main biochemical and hematological parameters, markers of cardiac and stress suffering (cortisol), in an amateur group of 8 late-adult cyclists (average age 60.9 years s.d. 4.1 years) before and after a continuous bicycle course of 9 days with an actual duration of 7 days and a daily average of 103.5 Km (total of 725 km) on an uncontrolled diet. Results: body weight, BMI, systolic and diastolic pressure did not vary significantly in pre- and post-cycling performance (p> 0.05). There was no significant change in the pre- and post-red blood cell count in the hemochromocytometric hematological parameters (p = 0.57), while hemoglobin values decreased significantly after pedaling (p = 0.03), as did the average cellular hemoglobin values and the average cell concentration of hemoglobin (p = 0.002 and p = 0.0006, respectively). The number of platelets, white blood cells, the absolute number of neutrophils, lymphocytes, eosinophils, basophils and monocytes, and the percentage of neutrophils, eosinophilic lymphocytes, basophils and monocytes did not change significantly (p> 0.05). With regard to basic biochemistry, there was no significant variation in the values of glucose, urea, creatinine, alanine amino transferase, alkaline phosphatase, cholinesterase and creatinine kinase (p> 0.05). Aspartate amino transferase was found to be significantly greater after pedaling (p = 0.03). The values of albumin, total proteins, lactate dehydrogenase, total calcium, inorganic phosphorus, total magnesium, total iron, sodium and potassium were statistically non-significant between pre and post phases. The lipid profile, total cholesterol, triglycerides, lipases, HDL and LDL were also statistically non-significant even if HDL values increased on average after cycling performance (before 48.9 \ub1 9.5 and after 53.8 \ub1 12.4) while LDL values decreased on average (before 118.5 \ub1 28.8 and after 101.6 \ub1 10.3). In the hormone-labeling and vitamin group, ferritin was statistically non-significant. Pre and post changes in the stress hormone cortisol, PSA, vitamin B12 and natriuretic B-type NT-proBNP peptide were statistically non-significant. Instead, folate decreased significantly following the cycling performance (p = 0.017). In protein biochemistry, apolipoprotein A1 was statistically significant (p = 0.038) increasing after pedaling, while apolipoprotein B, C-reactive protein and transferrin were statistically non-significant. CK MB mass and troponin I in the cardiac markers did not undergo significant changes between pre and post phases. Conclusions: despite the small size of the chosen sample, parameters analyzed between pre and post continuous physical effort lead to the conclusion and confirmation of many data in the literature and, that is, that sporting activity conducted in an important way can improve the biochemical/functional state and, therefore, the health of practising subjects even in late adults and/or the elderly. This could postpone physical psychic decline caused by the natural progression of years

Global Law Firms: Globalization and Organizational Spaces of Cross-Border Legal Work

The aim of this paper is not, however, to generically chart the rise of the global law firm; others have already done this. Instead, our interest lies in better understanding how existing geographies of globalization of law and lawyers, alongside the new geographies of professional partnership and legal work, have created opportunities and challenges for global law firms. More specifically, we seek to unravel the complexities of: (a) the factors driving the presence and absence of global law firms in different cities; and (b) the way that law firms have been reconfigured to operate as spatially distributed organizations present in cities as far apart as New York and Tokyo and London and Hong Kong. As we show, the decision to be there and the intricacies of operating as a global organization are both issues that have unique peculiarities when examined in relation to law and law firms, something that prevents generalization from existing studies of other professional industries. To date, however, limited attention has been paid to these organizational peculiarities. This paper seeks to fill this research void, something that is significant because the peculiarities of how global law firms operate provide the foundations upon which allow the likes of Clifford Chance to become lubricators of global capitalism through transnational lawyering and lawmaking