Development of a Short Trauma Screening Tool (STST) to Measure Child Trauma Symptoms: Establishing Content Validity

Purpose: The purpose of the study was to identify major symptom domain variables common to child trauma and create a prototype short trauma symptom screening tool (STST) intended for use in pediatric medical settings. Methods: This manuscript describes the first two phases of an on-going prospective mixed-method instrument development study. Phase 1 exploratory factor analysis was conducted with an archived LONGSCAN CBCL dataset to: (1) identify behavioral symptoms endorsed by children with known trauma exposure; and (2) generate a preliminary STST item pool. During Phase 2, researchers convened an expert panel (N = 10) and conducted Content Validity Index (CVI) procedures with the 20-item preliminary STST item pool, to further inform item retention, elimination and modification for an updated prototype STST. Findings: Expert quantitative scores yielded a CVI of 0.90 for the overall preliminary STST. The first two phases of this study assisted researchers with identifying 12 items that represent nine child trauma symptom domain variables, which include: (1) aggression/anger; (2) anxiety/fear; (3) sexual concerns; (4) elimination concerns; (5) somatic concerns; (6) depression; (7) dissociation; (8) physical acting out; and (9) dysregulation. Conclusions: The first two phases of STST development resulted in development of a brief, empirically-derived prototype screening tool that features 12 items operationalizing nine domains of child trauma symptoms. Developers can now advance to the next phase of STST development; feasibility assessment and psychometric testing

Overview of the National Physical Activity Plan

Allison Topper-Kleinfelter is a national leader in health promotion planning and marketing. Her specific area of expertise lies in social marketing, culture change, obesity prevention, public health planning, and development of public-private partnerships. Allison has helped to mobilize policy and practice changes to improve nutrition and physical activity behaviors. Allison is a national planning team contributor for the National Activity Plan, Comprehensive School Physical Activity Plan, Cardiovascular Disease Prevention Plan, and Children and Nature Strategies for Recreation and Healthcare. She is also Founder and CEO of achievABILITY where she provides consultation to public and private organizations working to improve nutrition and physical activity policies and practices among varied target audiences including state policy makers, school districts, child care organizations, parents, teens, and youth. Allison currently works with the National Coalition for Promoting Physical Activity to lead implementation of the nation’s first Physical Activity Plan

Population dynamics, life history characteristics, and environmental drivers of Neomysis americana in the Damariscotta River estuary

Mysid shrimp (Neomysis americana) play a pivotal role in estuarine food webs by linking primary producers to higher trophic levels and serving as an important food source for commercially valuable fish. Despite their ecological significance, mysids are often under sampled, leading to gaps in our understanding of their population dynamics and life history traits. My study investigated N. americana over a full year (June 2023 to May 2024) in the temperate Damariscotta River Estuary in Maine. My research focused on how environmental factors such as temperature, turbidity, salinity, chlorophyll-a, and zooplankton biomass affect mysid density and reproduction. Temperature emerged as a key factor, with warmer temperatures leading to higher mysid density. My results also indicated distinct overwintering cohorts, highlighting that at least a portion of the population remains in the estuary year-round, with seasonal shifts in size distribution. These findings enhance our understanding of N. americana\u27s ecological role in temperate estuaries, building on previous research of this important species

Sensory Electrical Stimulation Improves Foot Placement during Targeted Stepping Post-Stroke

Proper foot placement is vital for maintaining balance during walking, requiring the integration of multiple sensory signals with motor commands. Disruption of brain structures post-stroke likely alters the processing of sensory information by motor centers, interfering with precision control of foot placement and walking function for stroke survivors. In this study, we examined whether somatosensory stimulation, which improves functional movements of the paretic hand, could be used to improve foot placement of the paretic limb. Foot placement was evaluated before, during, and after application of somatosensory electrical stimulation to the paretic foot during a targeted stepping task. Starting from standing, twelve chronic stroke participants initiated movement with the non-paretic limb and stepped to one of five target locations projected onto the floor with distances normalized to the paretic stride length. Targeting error and lower extremity kinematics were used to assess changes in foot placement and limb control due to somatosensory stimulation. Significant reductions in placement error in the medial–lateral direction (p = 0.008) were observed during the stimulation and post-stimulation blocks. Seven participants, presenting with a hip circumduction walking pattern, had reductions (p = 0.008) in the magnitude and duration of hip abduction during swing with somatosensory stimulation. Reductions in circumduction correlated with both functional and clinical measures, with larger improvements observed in participants with greater impairment. The results of this study suggest that somatosensory stimulation of the paretic foot applied during movement can improve the precision control of foot placement

Neutrino masses from new generations

We reconsider the possibility that Majorana masses for the three known neutrinos are generated radiatively by the presence of a fourth generation and one right-handed neutrino with Yukawa couplings and a Majorana mass term. We find that the observed light neutrino mass hierarchy is not compatible with low energy universality bounds in this minimal scenario, but all present data can be accommodated with five generations and two right-handed neutrinos. Within this framework, we explore the parameter space regions which are currently allowed and could lead to observable effects in neutrinoless double beta decay, $\mu - e$ conversion in nuclei and $\mu \rightarrow e \gamma$ experiments. We also discuss the detection prospects at LHC.Comment: 28 pages, 4 figures. Version to be published. Some typos corrected. Improved figures 3 and

Researching my role for myself: Reacting to the Past and information literacy

In Minds on Fire: How Role-Immersion Games Transform College (Harvard UP, 2014) Mark Carnes argues that curricula such as “Reacting to the Past” engages students in subversive play in order to succeed in instilling concepts that have proved difficult to teach by other methods: critical thinking, empathy, leadership, a realistic view of history, and ultimately a better understanding of themselves. Such experiences, we have found, also foster inquiry and strategic thinking, core concepts of ACRL’s framework for information literacy. Participants will experience an abbreviated “game day” session from the Reacting to the Past curriculum, to illustrate how the role playing game can inspire student’s interest and creativity, especially as information users. Dr. Allison Belzer and experienced student players from her “Reacting” courses will lead the game play. Dr. Belzer will present her experience using the “Reacting” curriculum in her History courses, specifically how it impacts her students\u27 information literacy skills. Caroline Hopkinson will share her experience creating LibGuides for the course and how “Reacting” contributes to students understanding of “Research as Inquiry” and “Searching as Strategic Exploration.” The workshop aims to provide a good introduction to the games and their usefulness for developing information literacy concepts in order to inspire teachers to adopt the curriculum and librarians to support the curriculum. Tentative workshop agenda, using the game Rousseau, Burke and the Revolution in France, 1791. 10 minutes - introduce Reacting concept & discuss different games 40 minutes - distribute short roles to participants and divide group into 5 factions (Jacobins, Right, moderates, Crowd + indeterminates). Factions formulate strategies to win the game. Students assist, and factions each give a short speech (in character), then the group will vote on the issue at hand. 10 minutes - big group discussion about game and information literacy, including LibGuide & student and faculty reflection on how playing the game develops information literacy concepts (articulating a question, answering it via sources and incorporating those sources into their own text/speech) students weigh in 15 minutes Wrap up Including & Q & A Learning outcomes Participants will better understand how RTTP and other role playing games “hook” students by experiencing some game play. Participants will learn how RTTP contributes to information literacy from several perspectives, and draw their own conclusions from the experience

The Impact of a 4th Generation on Mixing and CP Violation in the Charm System

We study D0-D0 mixing in the presence of a fourth generation of quarks. In particular, we calculate the size of the allowed CP violation which is found at the observable level well beyond anything possible with CKM dynamics. We calculate the semileptonic asymmetry a_SL and the mixing induced CP asymmetry eta_fS_f which are correlated with each other. We also investigate the correlation of eta_fS_f with a number of prominent observables in other mesonic systems like epsilon'/epsilon, Br(K_L -> pi0 nu nu), Br(K+ -> pi+ nu nu), Br(B_s ->mu+ mu-), Br(B_d -> mu+ mu-) and finally S_psi phi in the B_s system. We identify a clear pattern of flavour and CP violation predicted by the SM4 model: While simultaneous large 4G effects in the K and D systems are possible, accompanying large NP effects in the B_d system are disfavoured. However this behaviour is not as pronounced as found for the LHT and RSc models. In contrast to this, sizeable CP violating effects in the B_s system are possible unless extreme effects in eta_fS_f are found, and Br(B_s ->mu+ mu-) can be strongly enhanced regardless of the situation in the D system. We find that, on the other hand, S_psi phi > 0.2 combined with the measured epsilon'/epsilon significantly diminishes 4G effects within the D system.Comment: 22 pages, 23 figures, v2 (references added

Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of ascaris reveals a novel fold and two discrete lipid-binding sites

Parasitic nematode worms cause serious health problems in humans and other animals. They can induce allergic-type immune responses, which can be harmful but may at the same time protect against the infections. Allergens are proteins that trigger allergic reactions and these parasites produce a type that is confined to nematodes, the nematode polyprotein allergens (NPAs). These are synthesized as large precursor proteins comprising repeating units of similar amino acid sequence that are subsequently cleaved into multiple copies of the allergen protein. NPAs bind small lipids such as fatty acids and retinol (Vitamin A) and probably transport these sensitive and insoluble compounds between the tissues of the worms. Nematodes cannot synthesize these lipids, so NPAs may also be crucial for extracting nutrients from their hosts. They may also be involved in altering immune responses by controlling the lipids by which the immune and inflammatory cells communicate. We describe the molecular structure of one unit of an NPA, the well-known ABA-1 allergen of Ascaris and find its structure to be of a type not previously found for lipid-binding proteins, and we describe the unusual sites where lipids bind within this structur

Intrauterine environmental and genetic influences on the association between birthweight and cardiovascular risk factors: studies in twins as a means of testing the fetal origins hypothesis

Evidence has accumulated that low birthweight is associated with several risk factors for cardiovascular disease. However, it is not known whether or not these associations are due to a programmed response to intrauterine malnutrition or genetic factors influencing both birthweight and cardiovascular risk factors. Twin studies offer a unique opportunity to distinguish between intrauterine and genetic origins of the association between birthweight and cardiovascular risk. In our twin cohort, low birthweight was associated with insulin resistance, lower HDL and shorter height within both dizygotic and monozygotic twin pairs, suggesting that these associations are, at least in part, independent of genetic factors. In contrast, low birthweight was associated with blood pressure, total and LDL cholesterol, fibrinogen and sympathetic activation within dizygotic twin pairs, but not within monozygotic twin pairs. These differences between dizygotic and monozygotic twins suggest that these associations are, at least in part, due to genetic factors. Therefore, both intrauterine environmental and genetic factors appear to play a role in the association between birthweight and cardiovascular risk factors. In the future, strategies may be developed targeted at improving or preventing impaired intrauterine growth. However, the effects of interventions that comprise changes in environment within the normal range may be limited due to the possible important role of genetic factor

Measurement of triple gauge boson couplings from W⁺W⁻ production at LEP energies up to 189 GeV

A measurement of triple gauge boson couplings is presented, based on W-pair data recorded by the OPAL detector at LEP during 1998 at a centre-of-mass energy of 189 GeV with an integrated luminosity of 183 pb⁻¹. After combining with our previous measurements at centre-of-mass energies of 161–183 GeV we obtain κ = 0.97_{-0.16}^{+0.20}, g_{1}^{z} = 0.991_{-0.057}^{+0.060} and λ = -0.110_{-0.055}^{+0.058}, where the errors include both statistical and systematic uncertainties and each coupling is determined by setting the other two couplings to their Standard Model values. These results are consistent with the Standard Model expectations