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High-Performance, Wearable Thermoelectric Generator Based on a Highly Aligned Carbon Nanotube Sheet
A high-performance, wearable thermoelectric generator (TEG) was fabricated with a highly aligned carbon nanotube (CNT) sheet. The aligned CNT sheet exhibits extraordinary electrical conductivity compared to disordered CNT sheets and also can be directly fabricated as a continuous TEG without metal electrode interconnects. This provides a significant reduction in contact resistance between TE legs and electrodes compared to traditional TEGs, resulting in higher power output. In addition, the continuity of the module without any disconnected parts provides high degrees of mechanical stability and durability. This robust and scalable approach to flexible TEG fabrication paves the way for CNT applications in lightweight, flexible, and wearable electronics
Stress-Related Growth Scale-Short Form: A Portuguese validation for cancer patients
Abstract background/objective: Cancer can be extremely disruptive, triggering high levels of distress, and at the same time transformative, promoting perceptions of positive life changes and growth. This study aims to analyze the psychometric proprieties of the Stress-Related Growth Scale Short-Form (SRGS-SF) in cancer patients.
Method: 209 Cancer patients heterogeneous in disease stage and diagnosis completed: clinical and sociodemographic information, Distress Thermometer, Positive and Negative Affect Schedule, Visual-analogue Scale of Perceived Positive Life Changes, and Stress-Related Growth Scale-Short Form.
Results: The analysis of internal structure pointed to an one-dimensional scale, with high reliability (.92) measured through the McDonald`s omega coefficient. Validity was also evidenced through significant correlations with other variables.
Conclusions: The Portuguese version of the SRGS-SF seems to present the necessary psychometric proprieties to be considered a valid and reliable short tool, to assess perceptions of growth following cancer and contribute to targeted and integrative psycho-oncological interventions.info:eu-repo/semantics/publishedVersio
Challenges for the recovery of the ozone layer
The recovery of stratospheric ozone from past depletion is underway owing to the 1987 Montreal Protocol and its subsequent amendments, which have been effective in phasing out the production and consumption of the major ozone-depleting substances (ODSs). However, there is uncertainty about the future rate of recovery. This uncertainty relates partly to unexpected emissions of controlled anthropogenic ODSs such as CCl₃F and slower-than-expected declines in atmospheric CCl₄. A further uncertainty surrounds emissions of uncontrolled short-lived anthropogenic ODSs (such as CH₂Cl₂ and CHCl₃), which observations show have been increasing in the atmosphere through 2017, as well as potential emission increases in natural ODSs (such as CH₃Cl and CH₃Br) induced by climate change, changes in atmospheric concentrations of greenhouse gases N₂O and CH₄, and stratospheric geoengineering. These challenges could delay the return of stratospheric ozone levels to historical values, (for example, the abundance in 1980), by up to decades, depending on the future evolution of the emissions and other influencing factors. To mitigate the threats to future ozone recovery, it is crucial to ensure that the Montreal Protocol and its amendments continue to be implemented effectively in order to have firm control on future levels of ODSs. This action needs to be supported by an expansion of the geographic coverage of atmospheric observations of ODSs, by enhancing the ability of source attribution modelling, and by improving understanding of the interactions between climate change and ozone recovery
The future of patient safety: Surgical trainees accept virtual reality as a new training tool
BACKGROUND: The use of virtual reality (VR) has gained increasing interest to acquire laparoscopic skills outside the operating theatre and thus increasing patients' safety. The aim of this study was to evaluate trainees' acceptance of VR for assessment and training during a skills course and at their institution.
METHODS: All 735 surgical trainees of the International Gastrointestinal Surgery Workshop 2006-2008, held in Davos, Switzerland, were given a minimum of 45 minutes for VR training during the course. Participants' opinion on VR was analyzed with a standardized questionnaire.
RESULTS: Fivehundred-twenty-seven participants (72%) from 28 countries attended the VR sessions and answered the questionnaires. The possibility of using VR at the course was estimated as excellent or good in 68%, useful in 21%, reasonable in 9% and unsuitable or useless in 2%. If such VR simulators were available at their institution, most course participants would train at least one hour per week (46%), two or more hours (42%) and only 12% wouldn't use VR. Similarly, 63% of the participants would accept to operate on patients only after VR training and 55% to have VR as part of their assessment.
CONCLUSION: Residents accept and appreciate VR simulation for surgical assessment and training. The majority of the trainees are motivated to regularly spend time for VR training if accessible
The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice
Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target. The plant polyphenol Curcumin has been proposed for dietary prevention of cancer. We therefore examined its effects on the human breast cancer cell line MDA-MB-231 in vitro and in a mouse metastasis model. Curcumin strongly induces apoptosis in MDA- MB- 231 cells in correlation with reduced activation of the survival pathway NF kappa B, as a consequence of diminished I kappa B and p65 phosphorylation. Curcumin also reduces the expression of major matrix metalloproteinases (MMPs) due to reduced NF kappa B activity and transcriptional downregulation of AP-1. NF kappa B/p65 silencing is sufficient to downregulate c-jun and MMP expression. Reduced NF kappa B/AP-1 activity and MMP expression lead to diminished invasion through a reconstituted basement membrane and to a significantly lower number of lung metastases in immunodeficient mice after intercardiac injection of 231 cells (p=0.0035). 68% of Curcumin treated but only 17% of untreated animals showed no or very few lung metastases, most likely as a consequence of down-regulation of NF kappa B/AP-1 dependent MMP expression and direct apoptotic effects on circulating tumor cells but not on established metastases. Dietary chemoprevention of metastases appears therefore feasible. Copyright (c) 2007 S. Karger AG, Basel
De Sitter ground state of scalar-tensor gravity and its primordial perturbation
Scalar-tensor gravity is one of the most competitive gravity theory to
Einstein's relativity. We reconstruct the exact de Sitter solution in
scalar-tensor gravity, in which the non-minimal coupling scalar is rolling
along the potential. This solution may have some relation to the early
inflation and present acceleration of the universe. We investigated its
primordial quantum perturbation around the adiabatic vacuum. We put forward for
the first time that exact de Sitter generates non-exactly scale invariant
perturbations. In the conformal coupling case, this model predicts that the
tensor mode of the perturbation (gravity wave) is strongly depressed.Comment: 9 page
Quantum spin liquid states in the two dimensional kagome antiferromagnets, ZnxCu4-x(OD)6Cl2
A three-dimensional system of interacting spins typically develops static
long-range order when it is cooled. If the spins are quantum (S = 1/2),
however, novel quantum paramagnetic states may appear. The most highly sought
state among them is the resonating valence bond (RVB) state in which every pair
of neighboring quantum spins form entangled spin singlets (valence bonds) and
the singlets are quantum mechanically resonating amongst all the possible
highly degenerate pairing states. Here we provide experimental evidence for
such quantum paramagnetic states existing in frustrated antiferromagnets,
ZnxCu4-x(OD)6Cl2, where the S = 1/2 magnetic Cu2+ moments form layers of a
two-dimensional kagome lattice. We find that in Cu4(OD)6Cl2, where distorted
kagome planes are weakly coupled to each other, a dispersionless excitation
mode appears in the magnetic excitation spectrum below ~ 20 K, whose
characteristics resemble those of quantum spin singlets in a solid state, known
as a valence bond solid (VBS), that breaks translational symmetry. Doping
nonmagnetic Zn2+ ions reduces the distortion of the kagome lattice, and weakens
the interplane coupling but also dilutes the magnetic occupancy of the kagome
lattice. The VBS state is suppressed and for ZnCu3(OD)6Cl2 where the kagome
planes are undistorted and 90% occupied by the Cu2+ ions, the low energy spin
fluctuations in the spin liquid phase become featureless
Cracking in asphalt materials
This chapter provides a comprehensive review of both laboratory characterization and modelling of bulk material fracture in asphalt mixtures. For the purpose of organization, this chapter is divided into a section on laboratory tests and a section on models. The laboratory characterization section is further subdivided on the basis of predominant loading conditions (monotonic vs. cyclic). The section on constitutive models is subdivided into two sections, the first one containing fracture mechanics based models for crack initiation and propagation that do not include material degradation due to cyclic loading conditions. The second section discusses phenomenological models that have been developed for crack growth through the use of dissipated energy and damage accumulation concepts. These latter models have the capability to simulate degradation of material capacity upon exceeding a threshold number of loading cycles.Peer ReviewedPostprint (author's final draft
Equivalent forms of Dirac equations in curved spacetimes and generalized de Broglie relations
One may ask whether the relations between energy and frequency and between
momentum and wave vector, introduced for matter waves by de Broglie, are
rigorously valid in the presence of gravity. In this paper, we show this to be
true for Dirac equations in a background of gravitational and electromagnetic
fields. We first transform any Dirac equation into an equivalent canonical
form, sometimes used in particular cases to solve Dirac equations in a curved
spacetime. This canonical form is needed to apply the Whitham Lagrangian
method. The latter method, unlike the WKB method, places no restriction on the
magnitude of Planck's constant to obtain wave packets, and furthermore
preserves the symmetries of the Dirac Lagrangian. We show using canonical Dirac
fields in a curved spacetime, that the probability current has a Gordon
decomposition into a convection current and a spin current, and that the spin
current vanishes in the Whitham approximation, which explains the negligible
effect of spin on wave packet solutions, independent of the size of Planck's
constant. We further discuss the classical-quantum correspondence in a curved
spacetime based on both Lagrangian and Hamiltonian formulations of the Whitham
equations. We show that the generalized de Broglie relations in a curved
spacetime are a direct consequence of Whitham's Lagrangian method, and not just
a physical hypothesis as introduced by Einstein and de Broglie, and by many
quantum mechanics textbooks.Comment: PDF, 32 pages in referee format. Added significant material on
canonical forms of Dirac equations. Simplified Theorem 1 for normal Dirac
equations. Added section on Gordon decomposition of the probability current.
Encapsulated main results in the statement of Theorem
The mu problem and sneutrino inflation
We consider sneutrino inflation and post-inflation cosmology in the singlet
extension of the MSSM with approximate Peccei-Quinn(PQ) symmetry, assuming that
supersymmetry breaking is mediated by gauge interaction. The PQ symmetry is
broken by the intermediate-scale VEVs of two flaton fields, which are
determined by the interplay between radiative flaton soft masses and higher
order terms. Then, from the flaton VEVs, we obtain the correct mu term and the
right-handed(RH) neutrino masses for see-saw mechanism. We show that the RH
sneutrino with non-minimal gravity coupling drives inflation, thanks to the
same flaton coupling giving rise to the RH neutrino mass. After inflation,
extra vector-like states, that are responsible for the radiative breaking of
the PQ symmetry, results in thermal inflation with the flaton field, solving
the gravitino problem caused by high reheating temperature. Our model predicts
the spectral index to be n_s\simeq 0.96 due to the additional efoldings from
thermal inflation. We show that a right dark matter abundance comes from the
gravitino of 100 keV mass and a successful baryogenesis is possible via
Affleck-Dine leptogenesis.Comment: 27 pages, no figures, To appear in JHE
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