Phytochemical screening and the antioxidant, antibacterial and antifungal activities of aqueous extracts from the leaves of Salvia officinalis planted in Morocco

The aqueous extract of the leaves of Salvia officinalis planted in Morocco is analyzed using different methods in order to study the different phytochemical components (phytochemical screening) and to test in parallel the antioxidant, antibacterial and antifungal activities. The main phytochemical components of salvia officinalis are: phenolics complex 13.87±1.96 mg E.AG/g, flavonoids 7.38±1.91mg E.Q/g and tannins 0.18±0.03 μg E.Cat/g, as well as different concentrations of saponins, alkaloids and mucilage.  The antioxidant activity is achieved by four different methods: the DPPH test (IC-50 = 8.2 μg/ml higher than BHT (1.2 μg/ml)); the ß-carotene decolorization test (the inhibition of oxidation of the aqueous extract (64.2%) was greater than the negative control (13. 87%)); the reducing power test (FRAP) (detection of a low reducing power of iron for the aqueous extract compared to quercetin) and the total antioxidant capacity (CAT), this test revealed an antioxidant capacity of 103.7±5.8 mg/g. The aqueous extract of salvia officinalis leaves showed antibacterial activity against four pathogenic bacteria: E. coli 57, K. pneumoniae, P. aeruginosa, S. aureus, noting MIC values of 0.25mg/ml; 0.125mg/ml; 0. The extract showed antifungal activity against two yeasts (S. sereveseae (0.25 mg/mlet C. albicans 0.25 mg/ml), using the agar diffusion method and the direct contact method

Kyste epidermoïde du quatrieme ventricule : a propos d’un cas

Les kystes épidermoïdes sont des tumeurs bénignes rares développées à partir d’inclusions ectodermiques. Ils siègent habituellement au niveau de l’angle ponto-cérébelleux, la région para-sellaire et la fosse temporale. Leur siège au niveau du quatrième ventricule est inhabituel. Nous rapportons le cas d’une jeune patiente de 44 ans admise pour un syndrome d’hypertension intracrânienne associé à des troubles de la marche. Le diagnostic de kyste épidermoïde du V4 fut évoqué sur les données de l’IRM puis confirmé en per opératoire et en histologie. L’exérèse chirurgicale a été subtotale en raison d’une adhérence de la capsule à la partie supérieure du plancher du V4. Après un recul de 18 mois, la patiente ne manifeste aucun signe de ré-évolution tumorale.Mots clés : chirurgie, IRM de diffusion, kyste épidermoïde, quatrième ventricl

Hydatidose du rachis cervical : A propos d’un cas

L’hydatidose intéresse l’os dans 0,5 à 2 % des cas, dont 44 % de localisations au niveau rachidien. L’étage cervical est la moins fréquente des localisations rachidiennes. Cette atteinte est grave par le risque de compression médullaire haute, et surtout par son caractère récidivant. Les auteurs présentent l’observation d’un jeune patient admis pour une tétraplégie progressive, due à une hydatidose vertébro-médullaire cervicale ; son diagnostic a été évoquée sur l’imagerie par résonance magnétique et confirmée par l’étude anatomopathologique

Clinical and histopathological findings of a rare sinonasal glomangiopericytoma

Glomangiopericytoma is a rare vascular neoplasm of the nasal cavity and paranasal sinuses that occurs during the sixth or seventh decade of life. It is categorized as a borderline tumor with low malignant potential and classified as a distinct entity of sinonasal tumors with perivascular myoid phenotype by the World Health Organization (WHO). We report the case of a 50-year-old woman with nasal obstruction and severe epistaxis. The nasal sinuses computed tomography (CT), and magnetic resonance imaging (MRI) demonstrated a 3.1 cm soft tissue mass occupying the upper part of the left nasal cavity invading the left paranasal sinuses and nasal septum, and the left eye medial rectus muscle. A total mass resection was performed by nasal endoscopy. The histological and immunohistochemical examination yielded the diagnosis of glomangiopericytoma. This case report aims to contribute to the knowledge of nasal neoplasms. The need for more data on this entity is the main obstacle to developing standardized treatment guidelines

Magnetic studies of amorphous Fe-Dy-B ribbons

We have studied the magnetization of melt spun amorphous Fe80−xDyxB20 alloys with 0 ≤ x ≤ 7.5 under magnetic fields up to 6T, and have analyzed the results at 4.2 K on the basis of the random magnetic anisotropy model. Exchange constant and local random anisotropy KL were evaluated. Using the Sarkis´s model, the local anisotropies per atom are found to be 1.75 107 and 4 107 erg/cm3 for Fe and Dy, respectively.We have studied the magnetization of melt spun amorphous Fe80−xDyxB20 alloys with 0 ≤ x ≤ 7.5 under magnetic fields up to 6T, and have analyzed the results at 4.2 K on the basis of the random magnetic anisotropy model. Exchange constant and local random anisotropy KL were evaluated. Using the Sarkis´s model, the local anisotropies per atom are found to be 1.75 107 and 4 107 erg/cm3 for Fe and Dy, respectively

Hydrogeochemical and Stable Isotope Data of the Groundwater of a Multi-Aquifer System in the Maknessy Basin (Mediterranean Area, Central Tunisia)

The Maknessy plain in central Tunisia is one of the most important agricultural basins in Tunisia. Given the semi-arid climate conditions, the irrigation of cultivated crops relies principally on the abstraction from groundwater resources. The assessment of the quality of the used water for agricultural purposes is crucial for safe production. Thus, the objective of this work is to assess the physicochemical quality of the irrigation water resources in this catchment area using a combined chemical, isotopic, and statistical approach. The waters analyzed are represented by two types of groundwater, mainly calcium hyper chloride and calcium sulfate. A multivariate statistical analysis (PCA and HCA) and a geochemical approach have been applied to study water quality as a function of chemical parameters, showing that the EC and TDS are the parameters influencing water quality. The stable isotopic compositions of the sampled waters range from -7.53 to -4.90% vs. VSMOW and from -53.6 to -32.2% vs. VSMOW for delta O-18 and delta H-2; they show the exchange between groundwater and rock and the evaporation effect. The isotopic data form three groups such as recent water, paleowater, and mixing water indicate the evaporation effect and interaction of the groundwater, and confirm that this aquifer has been recharged by current rainwater. So, these aquifers were recharged by precipitation derived from a mixture of cloud masses from the Atlantic Ocean and the Mediterranean Sea. The findings of this research are of important relevance for effective water resources management in this agro-based region. Indeed, the increased exploitation of these resources will induce a continuous reduction in the available resources and progressive degradation of the used water quality that may adversely impact the safe agricultural production and the economic resilience of the local population

Proteolysis in milk during experimental Escherichia coli mastitis

This work consisted of the intramammary infections (IMI) of 8 heifers by high doses of Escherichia coli to study both the proteolytic activity in milk and the resulting peptides. Therefore, a milking kinetic has been followed, and several parameters have been studied, such as proteose peptones ( PP) fraction ( quantitative and qualitative changes), plasmin activity (PA), milk somatic cell count (SCC), and bacterial count. A qualitative study of milk proteins and PP was performed by sodium dodecyl sulfate-PAGE, and the peptides recovered in PP during the acute phase of inflammation were amino-terminal micro-sequenced. A BSA increase in milk over time supported the hypothesis of an increase in the permeability of the epithelial barrier. A significant increase in PP content, considered to be an indicator of proteolysis, was observed from postinfusion hours (PIH) 12 to 48. Both the E. coli bacterial count and the SCC increased from PIH 3 to 216. Plasmin activity was increased noticeably from PIH 15 to 24. The respective increases in SCC, bacterial count, and PA suggest their involvement in a global mechanism responsible for the increase in proteolysis in milk after E. coli challenge. Somatic cell count and E. coli may be involved from PIH 3 to 216, and PA involvement might be highlighted during the maximum proteolysis, from PIH 15 to 24. A qualitative study of PP fraction by electrophoresis revealed the apparition of 5 peptide bands: P1 and P2 previously recovered during the lipopolysaccharide challenge, and E1 (27.0 kDa), E2 (15.5 kDa), and E3 (9.0 kDa) were specific to E. coli challenge; E1, E2, and E3 contained casein fragments. The roles played by leukocytes and E. coli are discussed

Magnetic properties in amorphous Co95­xDyxZr5 thin films

Amorphous Co95-xDyxZr5 thin films were prepared by RF sputtering and their magnetic properties were studied as a function of temperature and for the composition range 0<x<30. The mean field theory has been used to explain the temperature dependence of the magnetization. The exchange interactions between Co-Co and Dy-Co atom pairs have been evaluated. The magnetic phase diagrams are presented.Amorphous Co95-xDyxZr5 thin films were prepared by RF sputtering and their magnetic properties were studied as a function of temperature and for the composition range 0<x<30. The mean field theory has been used to explain the temperature dependence of the magnetization. The exchange interactions between Co-Co and Dy-Co atom pairs have been evaluated. The magnetic phase diagrams are presented

Cas rare de dysphagie révélant une Achalasie de l’œsophage

Le mégaoesophage ou achalasie reste une affection rare sous nos cieux. Ce travail rapporte un cas de dysphagie aigue admis aux urgences révélant un mégaoesophage idiopathique. Le but de cette observation est d’élaborer une démarche diagnostic devant toute dysphagie et de savoir mettre en oeuvre les examens complémentaires pour la confirmer ainsi que les différentes possibilités thérapeutiques qui s’offrent à nous pour traiter cette pathologie rare