PENGARUH STRES KERJA DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN PT. INDOMOBIL FINANCE INDONESIA CABANG GATOT SUBROTO BANDUNG

ABSTRAK Kemajuan suatu perusahaan atau instansi sangat ditentukan oleh kualitas sumber daya manusia yang sesuai dengan sasaran kerja pegawai dan prilaku kerja, khususnya kinerja. Melalui kinerja karyawan yang meningkat, maka efektivitas dan produktivitas perusahaan pun akan meningkat pula. Menyadari pentingnya sumber daya manusia bagi kelangsungan dan kemajuan instansi, maka isntansi harus memberikan perhatian khusus dan memandang sumber daya manusia lebih dari sekedar asset organisasi, tetapi juga sebagai mitra dalam menjalankan roda organisasi. Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh Stres kerja dan disiplin kerja terhadap kinerja karyawan pada PT. Indomobil Finance Indonesia Cabang Gatot subroto Bandung baik secara parsial maupun simultan. Metode penelitian yang digunakan adalah deskriptif dan verifikatif. Jumlah populasi dalam penelitian ini adalah 65 orang dan menggunakan teknik sample jenuh dimana seluruh populasi dijadikan sebagai sample dengan tingkat kesalahan 5% responden Teknik pengumpulan data yang digunakan adalah observasi, wawancara dan menyebarkan kuesioner. Metode analisis yang digunakan adalah regresi linier ganda, korelasi ganda, koefesien determinasi dan uji F, uji T. Hasil penelitian menunjukan bahwa stres kerja, disiplin kerja dan kinerja karyawan dapat dikatakan sudah baik. Stres kerja dan disiplin Kerja memberikan pengaruh kuat terhadap peningkatan kinerja pegawai yaitu sebesar 57,2% Pengaruh variabel yang kuat adalah disiplin kerja dengan koefisien sebesar 0,439. Sedangkan stres kerja koefisiennya sebesar 0,133. Kata Kunci : Stres kerja, Disiplin Kerja dan Kinerja Karyawa

Isolation and selection of Bradyrhizobium from the root nodules of indigo plants (Indigofera tinctoria L.)

This research was conducted from 2004 to 2005 to isolate and select Bradyrhizobium from the root nodules of indigo plants (Indigofera tinctoria L.). For isolation of Bradyrhizobium, root nodules were collected from indigo plants. Fourteen Bradyrhizobium isolates were identified depending on colony, morphological and biochemical characteristics. Out of fourteen isolates, six (HSTU-IR2, HSTU-IR3, HSTU-IR4, HSTU-IR9, HSTU-IR10 and HSTU-IR14) were found promising with respect to nodulation, shoots and roots weights and N fixation by the indigo plants grown inside the Leonard Bottle Jar Assembly (LBJA).Key words: Bradyrhizobium, isolation, selection, root nodules, indigo plants

Effect of salt stress on germination and early seedling growth of rice (Oryza sativa L.)

The response of twelve rice varieties against six salinity levels (0, 4, 8, 12, 16 and 20 dS m-1) were studied at germination and early seedling stages. Data were analyzed using SAS and means were separated by LSD for final germination percentage (FGP), speed of germination (SG), germinationenergy percentage (GE%), plumule and radical length and plumule and radical dry weight. Based on dry matter yield reduction, rice varieties were classified as tolerant (T), moderately tolerant (MT), moderately susceptible (MS) or susceptible (S). Germination was completely arrested at 20 dS m-1 salt concentration. Salinity decreased FGP, SG, GE % and led to reduction in shoot and root length and dry weight in all varieties and the magnitude of reduction increased with increasing salinity stress. Ricevarieties MR211, IR20, BR40 and MR232 showed greater salt tolerance during germination (germinated at 12 dS m-1 salinity). However, MR211, MR232 and IR20 performed better based on dry matter yield reduction. The result suggested that MR211, MR232 and IR20 might be used for further study of salinity effect on growth processes and physiological consequences at advanced stage of growth, since salt tolerance of a crop at germination and early seedling stage may not correspond to that at advanced stage

Serum amino acid abnormalities in pediatric patients with chronic renal failure with and without history of thromboembolic manifestations

Background: Plasma amino acid concentrations have been reported to be abnormal in patients with chronic renal failure. L-Arginine has been used to improve endothelial function by increasing nitric oxide (NO) bioavailability. The present study aim at investigating the status of plasma amino acids in pediatric patients with chronic renal failure (CRF) on regular hemodialysis (HD) with and without history of thromboembolic manifestations.Methods: The study included 21 hemodialysis patients subdivided into two groups (those with no history of thromboembolic manifestations and those with positive history of thromboembolic manifestations) The control group included 13 age and sex matched apparently healthy subjects, After careful history taking, clinical examination, the following laboratory investigations were performed: serum calcium, phosphate, albumin, and creatinine (for controls only), complete blood count (CBC) and serum amino acid analysis.Results: HD patients had a significantly lower concentration of threonine, valine, methionine, leucine, tyrosine, phenylalanine and tryptophane than the control group (p= 0.032, 0.020, 0.046, 0.011, 0.000, 0.022, and 0.004 respectively). There was no significant difference between HD patients and the control group as regard aspartic acid, serine, asparagine, glutamic acid, proline, glycine, alanine, cystine, isoleucine, lysine, histidine, and arginine. The mean serum L-arginine level was lower in 61.9% of HD patients than the mean of the controls with no significant difference. L-Arginine concentration was not significantly different between HD patients with and without history of thromboembolic manifestations.Conclusion: Several abnormalities in amino acids were present in HD patients compared to controls. The mean serum L-arginine level was lower in 61.9% of HD patients than the mean of the controls with no significant difference. L-Arginine concentration was not significantly different between HD patients with and without history of thromboembolic manifestations. HD patients without history of thromboembolic manifestations had significantly lower glutamic acid concentrations and significantly higher phenylalanine concentrations than HD patients with history of thromboembolic manifestations.Keywords: Serum amino acid; Chronic renal failure; L-Arginin

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

LKB1 is a master kinase that regulates metabolism and growth through adenosine monophosphate-activated protein kinase (AMPK) and 12 other closely related kinases. Liver-specific ablation of LKB1 causes increased glucose production in hepatocytes in vitro and hyperglycaemia in fasting mice in vivo. Here we report that the salt-inducible kinases (SIK1, 2 and 3), members of the AMPK-related kinase family, play a key role as gluconeogenic suppressors downstream of LKB1 in the liver. The selective SIK inhibitor HG-9-91-01 promotes dephosphorylation of transcriptional co-activators CRTC2/3 resulting in enhanced gluconeogenic gene expression and glucose production in hepatocytes, an effect that is abolished when an HG-9-91-01-insensitive mutant SIK is introduced or LKB1 is ablated. Although SIK2 was proposed as a key regulator of insulin-mediated suppression of gluconeogenesis, we provide genetic evidence that liver-specific ablation of SIK2 alone has no effect on gluconeogenesis and insulin does not modulate SIK2 phosphorylation or activity. Collectively, we demonstrate that the LKB1-SIK pathway functions as a key gluconeogenic gatekeeper in the liver

Perceptions on Awareness, Knowledge and Confidence in Providing Information and Management of Snake-related Injuries by Medical Students in Sarawak, Malaysia

The World Health Organization (WHO) has categorised snake-related injuries as a neglected tropical disease which can cause permanent disability, or worse, can lead to death if not treated timely and appropriately. Medical students are exposed to snakebite patients predominantly in their clinical years and depending on the location of their medical postings. This study aimed to determine the perceived awareness, knowledge and confidence level of medical students in providing information and managing snake-related injuries. A quantitative cross-sectional study was designed and the data were collected using a Likert scale questionnaire. The perceived awareness, knowledge and confidence level between pre-clinical and clinical students were tested by an independent sample t-test. A p-value of ≤ .05 was interpreted as statistically significant. Analysis revealed a statistically significant difference of perceived knowledge (p= .009) and perception of confidence level (p= .025) between clinical and pre-clinical students. However, no difference was found in terms of perceived awareness (p> .05). Clinical medical students have a better perception of knowledge and confidence level in providing information and managing snake-related injuries than pre-clinical students. An indepth study on this topic should be conducted to include all medical students in Malaysia. Steps should be taken to improve the knowledge and confidence level of medical students in managing snake-related injuries in Malaysia

Evaluation of growth and yield potentialities of local boro rice varieties in south-west region of Bangladesh

A field experiment was conducted to evaluate the growth and yield performance of local boro rice varieties. Twelve local boro rice varieties were included in this study namely Nayon moni, Tere bale, Bere ratna, Ashan boro, Kajol lata, Koijore, Kali boro, Bapoy, Latai balam, Choite boro, GS one and Sylhety boro. Growth parameters viz. plant height and number of tillers hill-1(at different days after transplanting); yield contributing characters such as effective tillers hill-1, panicle length, number of grains panicle-1, filled grains panicle-1, thousand grain weight, grain yield, straw yield, biological yield and harvest index were recorded. The result revealed that the plant height and number of tillers hill-1 at different days after transplanting varied significantly among the varieties. The plant height for all the varieties and number of tillers hill-1 for most of the varieties increased up to harvest. At harvest, the tallest plant (123.80 cm) was recorded in Bapoy and the shortest (81.13 cm) was found in GS one. The maximum number of tillers hill-1 (46.00) was observed in Sylhety boro and the minimum (19.80) in Bere ratna. All of the parameters of yield and yield contributing characters differed significantly at 1% level except grain yield, biological yield and harvest index. The maximum number of effective tillers hill-1 (43.87) was recorded in the variety Sylhety boro and the minimum (17.73) was found in Bere ratna. The highest (110.57) and the lowest (42.13) number of filled grains panicle-1 was observed in the variety Koijore and Sylhety boro, respectively. Thousand grain weight was the highest (26.35g) in Kali boro and the lowest (17.83g) in GS one. Grain yield was not differed significantly among the varieties but numerically the highest grain yield (5.01 t ha-1) was found in the variety Koijore and the lowest in GS one(3.17 t ha-1). Considering all parameters the varieties Koijore (5.01tha-1), Choite boro, Sylhety boro, Ashan boro, Bere ratna performed better for the southwest region of Bangladesh

Hepatitis B virus infection among different sex and age groups in Pakistani Punjab

<p>Abstract</p> <p>Background</p> <p>Hepatitis B virus (HBV) infection is a serious health problem in the developing countries including Pakistan. Various risk factors are responsible for the spread of this infectious disease. Prevalence of HBV infection in apparently suspected individual of Punjab province of Pakistan was analyzed during January 2008 to December 2010. Current study was aimed to investigate the epidemiology and risk factors of HBV infection.</p> <p>Methodology</p> <p>Four thousand eight hundred and ninety patients suffering from chronic liver disease were screened for the presence of HBV DNA using qualitative Real Time PCR methodology to confirm their status of infection. A predesigned standard questionnaire was filled for all the patients that included information about the possible risk factors.</p> <p>Results</p> <p>A total of 4890 ELISA positive patients were screened for Hepatitis B virus infection. Of these 3143 were positive for HBV, includes 68.15% males and 31.85% females. Male were observed to be more frequently infected as compared to the female with a positivity ratio of 2.14: 1. The rate of infection increases with the passage of time in the course of three years. Highest frequency of infection was found in the age of 21-30 was 34.93% followed by 23.83% in 31-40. Only (13.39%) were belonging to the age group 11-20 year. The rate of infection declines with increasing age as shown by age groups 41-50 (16.13%) and 51-60 (7.09%). While children aged 0-10 and very old >60 age groups were very less frequently 1.49% and 1.65% infected respectively. Important risk factors contributing to HBV spread include barber risk (23.60%), blood transfusion (4.04%), History of injection 26.19%, Reuse of syringes 26.60%, dental risk (11.20%) and surgical procedure (4.26%). Among the entire respondents trend sharing personal items was very common. History of injection, barber risk, surgery and dental procedure and reuse of syringes appear as major risk factors for the transmission.</p> <p>Conclusion</p> <p>Male were more frequently exposed to the risk factors as compared to female. Similarly the younger age group had high rate of infection as compared to the children's and the older age groups. Reuse of syringes', barber risk and History of injection were main risk identified during the present study. To lower HBV transmission rate Government should take aggressive steps towards massive awareness and vaccination programs to decrease the burden of HBV from the Punjab province of Pakistan.</p

The association between balance and free-living physical activity in an older community-dwelling adult population: a systematic review and meta-analysis

Abstract Background Poor balance is associated with an increased risk of falling, disability and death in older populations. To better inform policies and help reduce the human and economic cost of falls, this novel review explores the effects of free-living physical activity on balance in older (50 years and over) healthy community-dwelling adults. Methods Search methods: CENTRAL, Bone, Joint and Muscle Trauma Group Specialised register and CDSR in the Cochrane Library, MEDLINE, EMBASE, CINAHL, PsychINFO, and AMED were searched from inception to 7th June 2016. Selection criteria: Intervention and observational studies investigating the effects of free-living PA on balance in healthy community-dwelling adults (50 years and older). Data extraction and analysis: Thirty studies were eligible for inclusion. Data extraction and risk of bias assessment were independently carried out by two review authors. Due to the variety of outcome measures used in studies, balance outcomes from observational studies were pooled as standardised mean differences or mean difference where appropriate and 95% confidence intervals, and outcomes from RCTs were synthesised using a best evidence approach. Results Limited evidence provided by a small number of RCTs, and evidence from observational studies of moderate methodological quality, suggest that free-living PA of between one and 21 years’ duration improves measures of balance in older healthy community-dwelling adults. Statistical analysis of observational studies found significant effects in favour of more active groups for neuromuscular measures such as gait speed; functionality using Timed Up and Go, Single Leg Stance, and Activities of Balance Confidence Scale; flexibility using the forward reach test; and strength using the isometric knee extension test and ultrasound. A significant effect was also observed for less active groups on a single sensory measure of balance, the knee joint repositioning test. Conclusion There is some evidence that free-living PA is effective in improving balance outcomes in older healthy adults, but future research should include higher quality studies that focus on a consensus of balance measures that are clinically relevant and explore the effects of free-living PA on balance over the longer-term