Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Bio-efficacy of newer insecticides and bio-pesticides against termite on chickpea in arid region of Rajasthan

The seed treatment, as well as soil application of imidacloprid 600 FS @ 5 ml/kg + Beauveria bassiana 1.15 WP @ 2 kg /ha, was found most effective against termite (9.34% plant damage) after 110 days of crop sowing, followed by fipronil 5 SC @ 5 ml/ kg + Metarrihizium anisopliae 1.15 WP @ 2 kg/ha (10%) and clothianidin 50 WDG @ 2 g/ kg + Beauveria bassiana 1.15 WP @ 2 kg /ha (10.62%). The treatments alone seed treatment of imidacloprid 600 FS @ 5 ml/ kg seed (11.56%) followed by fipronil 5 SC @ 5 ml/ kg seed (12.03%) and clothianidin 50 WDG @ 2 g/ kg seed (12.65%) were found moderately effective while, bio-pesticides viz., Metarrihizium anisopliae 1.15 WP @ 2 kg/ha and Beauveria bassiana 1.15 WP @ 2 kg /ha with 15.78 and 15.47 per cent plant damage were found least effective for controlling the termite population. The maximum yield was obtained in imidacloprid 600 FS + Beauveria bassiana 1.15 WP (18.70 q ha-1) followed by fipronil 5 SC + Metarrihizium anisopliae 1.15 WP (18.20 q ha-1) and clothianidin 50 WDG + Beauveria bassiana1.15 WP (18.00 q ha-1), respectively

Genomic and biotechnological interventions for crop improvement in cucurbitaceous crops: A review

The cucurbitaceous family has comprised with diverse economically important cucurbits. It primarily comprised of 118 genera and 825 species which being consumed as food worldwide since the domestication of the plants. In India, cucurbits are being grown throughout regions of the country including hot semi-arid and arid zones. With the advent of genomic breakthrough, a large number of genomic and biotechnological interventions have been developed in cucurbitaceous crops. The plenty of molecular markers are available in cucurbits and these markers were deployed to assess the genetic diversity and mapping of the QTLS/genes of interest. The success in development of genomic tools may happens by genome sequencing of mostly important cucurbitaceous crops such as watermelon, cucumber, muskmelon, bottle gourd, pumpkins. Transgenic and non-transgenic plants were developed in various cucurbitaceous crops by employing of Agrobacterium-mediated transformation and CRISPR/CAS9 approach, respectively. Thus cucurbitaceous crops have been considerably exploited at molecular level and biotechnological interventions were developed for crop improvement. However, a comprehensive report in cucurbitaceous crops regarding genomic and biotechnological developments is not available in public domain. Therefore, in the present review, we have collected the information related to genomics and biotechnology in cucurbits and emphasized on some successful interventions

Genomic and biotechnological interventions for crop improvement in cucurbitaceous crops: A review

The cucurbitaceous family has comprised with diverse economically important cucurbits. It primarily comprised of 118 genera and 825 species which being consumed as food worldwide since the domestication of the plants. In India, cucurbits are being grown throughout regions of the country including hot semi-arid and arid zones. With the advent of genomic breakthrough, a large number of genomic and biotechnological interventions have been developed in cucurbitaceous crops. The plenty of molecular markers are available in cucurbits and these markers were deployed to assess the genetic diversity and mapping of the QTLS/genes of interest. The success in development of genomic tools may happens by genome sequencing of mostly important cucurbitaceous crops such as watermelon, cucumber, muskmelon, bottle gourd, pumpkins. Transgenic and non-transgenic plants were developed in various cucurbitaceous crops by employing of Agrobacterium-mediated transformation and CRISPR/CAS9 approach, respectively. Thus cucurbitaceous crops have been considerably exploited at molecular level and biotechnological interventions were developed for crop improvement. However, a comprehensive report in cucurbitaceous crops regarding genomic and biotechnological developments is not available in public domain. Therefore, in the present review, we have collected the information related to genomics and biotechnology in cucurbits and emphasized on some successful interventions

Khejri (Prosopis cineraria) research for horticultural harnessing and environmental services: an appraisal

Dry-land agriculture has enormous potential in ensuring nutritious food to the inhabitants and eco-restoration. Khejri (Prosopis cineraria) is a life-line tree of the Thar Desert. It is the most important component of the traditional farming systems of arid and semi-arid region of the north-western part of India. It tolerates extreme edapho-climatic conditions with lush-green foliage and bears fruits that too during the driest period. Its nutritious leaf-fodder (loong) and tender pods (sangri) used extensively. Sangri is sold fresh and dehydrated at high price, and it is the main constituent of Panchkutta vegetable cooking. Prior to CIAH - Khejri Technology, the rural people used to collect tender pods from the natural seedling trees and there was no quality standard for it. For horticultural exploitation, a series of technological advancements have been made at ICAR-CIAH and first-time recommended are patch-budding for vegetative propagation for conservation of&nbsp; the elite genotypes and mass-multiplication of true-to-type plants in the nursery, in-situ orchard establishment by bud-grafting, induction of thornlessness in plants, variety-Thar Shobha, crop-regulation to harvest both sangri and loong annually, on-farm value-addition and diversified crop-combination models adopting HBCPSMA concept such as Organic Panchkuta, native, multi-purpose and intensive production. Based on crop-commodity potentialities, khejri planting models viz., KM–1, KM–3, KM–7, KM–9 and KM–11 exhibited tremendous scope for desert horticultural promotion and agro-ecological prosperity