1,731 research outputs found

    Non-abelian T-duality, Ramond Fields and Coset Geometries

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    We extend previous work on non-abelian T-duality in the presence of Ramond fluxes to cases in which the duality group acts with isotropy such as in backgrounds containing coset spaces. In the process we generate new supergravity solutions related to D-brane configurations and to standard supergravity compactifications.Comment: 35 pages, Late

    Three-Year Clinical Evaluation of in Ceram Zirconia Bridges.

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    INTRODUCTION: The demand for esthetic restorations has led to the development of materials that are metal free. These materials must have adequate strength to be an alternative for the fabrication of fixed partial dentures in posterior segments of the dental arches. PURPOSE: The aim of the present study was to investigate in a long-term perspective whether the strength of the In Ceram Zirconia material is sufficient for use in posterior bridges. MATERIAL AND METHODS: Sixteen patients, who were between 23 and 50 years of age, with indications for a fixed denture replacing premolar or molar, were examined for participation in the study. Eighteen bridges were constructed with one or two pontics and two abutments, one on each side of the pontic. The patients were informed about risks of, and alternatives to, the proposed therapy. The supporting teeth were prepared with chamfer finish line and lack ofsharp line angles. Impressions were made with a rigid standard tray with an A-silicone putty soft and light-body materials (Aquasil, Dentsply). The laboratory procedures were performed by a laboratory autho rised by the Vita supplier. Ten of the bridges were cemented permanently with zinc phosphate cement and eight with glass ionomer cement. Clinical evaluation of the bridges were performed according to the California Dental Association’s quality evaluation system. RESULT: After three year evaluation all eighteen bridges were without signs of or any change in colour, and marginal integrity. CONCLUSION: In Ceram Zirconia is a potential alternative for full ceramic bridges in the posterior segments

    Genetics and Epigenetics of Nasal Polyposis: A Systematic Review

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    [EN] Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and paranasal sinuses that is often associated with nasal polyposis (CRSwNP) in the most severe cases. As in other complex diseases, genetic factors are thought to play an important role in the risk and development of the disease. Environment may also modulate the epigenetic signature in affected patients. In the present systematic review, we aimed to compile all published data on genetic and epigenetic variations in CRSwNP since 2000. We found 104 articles, 24 of which were related to epigenetic studies. We identified more than 150 genetic variants in 99 genes involved in the pathogenesis of nasal polyposis. These were clustered into 8 main networks, linking genes involved in inflammation and immune response (eg, MHC), cytokine genes (eg, TNF), leukotriene metabolism, and the extracellular matrix. A total of 89 miRNAs were also identified; these are associated mainly with biological functions such as the cell cycle, inflammation, and the immune response. We propose a potential relationship between genes and the miRNAs identified that may open new lines of investigation. An in-depth knowledge of gene variants and epigenetic traits could help us to design more tailored treatment for patients with CRSwNP.Thematic Network of Cooperative Research in Health - RETICS (Red temática de investigación en salud Asma, Reacciones Adversas y Alérgicas, ARADYAL) of the Instituto de Salud Carlos II

    The Tensor Hierarchies of Pure N=2,d=4,5,6 Supergravities

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    We study the supersymmetric tensor hierarchy of pure (gauged) N=2,d=4,5,6 supergravity and compare them with those of the pure, ungauged, theories (worked out by Gomis and Roest for d=5) and the predictions of the Kac-Moody approach made by Kleinschmidt and Roest. We find complete agreement in the ungauged case but we also find that, after gauging, new Stueckelberg symmetries reduce the number of independent "physical" top-forms. The analysis has to be performed to all orders in fermion fields. We discuss the construction of the worldvolume effective actions for the p-branes which are charged with respect to the (p+1)-form potentials and the relations between the tensor hierarchies and p-branes upon dimensional reduction.Comment: LaTeX2e file, 20 pages, 1 figure Results refined by extension of the analysis to all orders in fermion

    ÍNDICE DE BARTHEL: ¿ADECUADO PARA PLANIFICAR NECESIDADES AL ALTA HOSPITALARIA?

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    Nursing professionals carry out important work evaluating the needs of patients and care-givers. They also provide the required care, as well as transmit the knowledge and skills of self-care. In the planning of care it is necessary to evaluate the Basic Activities of Daily Living (BADL), essential for self-care, such as cleaning and dressing oneself, using the bathroom among others. The objective of the present work is to evaluate the capacity of self-care in elderly people previous to hospital discharge or in the same way, measure the level of dependence/independence in the execution of BADL. For this, the Barthel index has been used as an evaluation tool. The hypothesis tested is the suitability of this instrument in the evaluation of planning nursing care. The above mentioned hypothesis has been contrasted with the application of BI in 32 patients above the age of 65 years admitted to the department of Internal Medicine at the Coria City Regional Hospital.Los profesionales de Enfermería desarrollamos una importante labor en la evaluación de las necesidades del enfermo y los cuidadores, y en proporcionar los cuidados requeridos, así como en transmitir conocimientos y habilidades para el autocuidado. En la planificación de cuidados, necesitamos valorar las Actividades Básicas de la Vida Diaria (ABVD), las cuales son esenciales para el autocuidado, es decir, asearse, vestirse, usar el baño etc. El objetivo del presente trabajo es valorar la capacidad de autocuidado en ancianos previa al alta hospitalaria, o lo que es lo mismo, medir el grado de dependencia/independencia para realizar A.B.V.D. Para ello hemos utilizado como herramienta de valoración el índice de Barthel y planteamos como hipótesis de partida, la idoneidad de este instrumento de evaluación para la planificación Cuidados de Enfermería. La hipótesis de partida la hemos contrastado con la aplicación del IB a 32 pacientes mayores de 65 años ingresados en la planta de Medicina Interna del Hospital Comarcal Ciudad de Coria

    Mesons from (non) Abelian T-dual backgrounds

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    In this work we study mesonic excitations in a Quantum Field Theory dual to the non Abelian T-dual of AdS5×S5AdS_5\times S^5, using a D6 brane probe on the Sfetsos-Thompson background. Before and after the duality, we observe interesting differences between the spectra and interpret them. The spectrum of masses and the interactions among mesonic excitations teach valuable lessons about the character of non-Abelian T-duality and its implications for Holography. The case of Abelian T-duality is also studied.Comment: 26 pages plus many long appendice

    Utility of a thematic network in primary health care: a controlled interventional study in a rural area

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    BACKGROUND: UniNet is an Internet-based thematic network for a virtual community of users (VCU). It supports a virtual multidisciplinary community for physicians, focused on the improvement of clinical practice. This is a study of the effects of a thematic network such as UniNet on primary care medicine in a rural area, specifically as a platform of communication between specialists at the hospital and doctors in the rural area. METHODS: In order to study the effects of a thematic network such as UniNet on primary care medicine in a rural area, we designed an interventional study that included a control group. The measurements included the number of patient displacements due to disease, number of patient hospital stays and the number of prescriptions of drugs of low therapeutic utility and generic drug prescriptions by doctors. These data were analysed and compared with those of the control center. RESULTS: Our study showed positive changes in medical practice, reflected in the improvement of the evaluated parameters in the rural health area where the interventional study was carried out, compared with the control area. We discuss the strengths and weaknesses of UniNet as a potential medium to improve the quality of medical care in rural areas. CONCLUSION: The rural doctors had an effective, useful, user-friendly and cheap source of medical information that may have contributed to the improvement observed in the medical quality indices

    Illness perceptions and explanatory models of viral hepatitis B & C among immigrants and refugees: a narrative systematic review.

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    © 2015 Owiti et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.BACKGROUND: Hepatitis B and C (HBV, HCV) infections are associated with high morbidity and mortality. Many countries with traditionally low prevalence (such as UK) are now planning interventions (screening, vaccination, and treatment) of high-risk immigrants from countries with high prevalence. This review aimed to synthesise the evidence on immigrants' knowledge of HBV and HCV that might influence the uptake of clinical interventions. The review was also used to inform the design and successful delivery of a randomised controlled trial of targeted screening and treatment. METHODS: Five databases (PubMed, CINHAL, SOCIOFILE, PsycINFO & Web of Science) were systematically searched, supplemented by reference tracking, searches of selected journals, and of relevant websites. We aimed to identify qualitative and quantitative studies that investigated knowledge of HBV and HCV among immigrants from high endemic areas to low endemic areas. Evidence, extracted according to a conceptual framework of Kleinman's explanatory model, was subjected to narrative synthesis. We adapted the PEN-3 model to categorise and analyse themes, and recommend strategies for interventions to influence help-seeking behaviour. RESULTS: We identified 51 publications including quantitative (n = 39), qualitative (n = 11), and mixed methods (n = 1) designs. Most of the quantitative studies included small samples and had heterogeneous methods and outcomes. The studies mainly concentrated on hepatitis B and ethnic groups of South East Asian immigrants residing in USA, Canada, and Australia. Many immigrants lacked adequate knowledge of aetiology, symptoms, transmission risk factors, prevention strategies, and treatment, of hepatitis HBV and HCV. Ethnicity, gender, better education, higher income, and English proficiency influenced variations in levels and forms of knowledge. CONCLUSION: Immigrants are vulnerable to HBV and HCV, and risk life-threatening complications from these infections because of poor knowledge and help-seeking behaviour. Primary studies in this area are extremely diverse and of variable quality precluding meta-analysis. Further research is needed outside North America and Australia

    Usefulness of multimodal MR imaging in the differential diagnosis of HaNDL and acute ischemic stroke

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    <p>Abstract</p> <p>Background</p> <p>Syndrome of transient Headache and Neurological Deficits with cerebrospinal fluid Lymphocitosis (HaNDL) is a rare disease which can present with focal neurological deficits and mimic stroke. A neurologist-on-duty faced with a HaNDL patient in the first hours might erroneously decide to use thrombolytic drugs, a non-innocuous treatment which has no therapeutic effect on this syndrome.</p> <p>Case Presentation</p> <p>We present a case where neuroimaging, together with the clinical picture, led to a presumed diagnosis of HaNDL avoiding intravenous thrombolysis.</p> <p>Conclusions</p> <p>This report shows the usefulness of multimodal MR imaging in achieving early diagnosis during an acute neurological attack of HaNDL. Our experience, along with that of others, demonstrates that neuroimaging tests reveal the presence of cerebral hypoperfusion in HaNDL syndrome</p
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