42,554 research outputs found
Maximum Production Of Transmission Messages Rate For Service Discovery Protocols
Minimizing the number of dropped User Datagram Protocol (UDP) messages in a network is regarded as a challenge by researchers. This issue represents serious problems for many protocols particularly those that depend on sending messages as part of their strategy, such us service discovery protocols. This paper proposes and evaluates an algorithm to predict the minimum period of time required between two or more consecutive messages and suggests the minimum queue sizes for the routers, to manage the traffic and minimise the number of dropped messages that has been caused by either congestion or queue overflow or both together. The algorithm has been applied to the Universal Plug and Play (UPnP) protocol using ns2 simulator. It was tested when the routers were connected in two configurations; as a centralized and de centralized. The message length and bandwidth of the links among the routers were taken in the consideration. The result shows Better improvement in number of dropped messages `among the routers
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Design and Measurements of a Five Independent Band Patch Antenna for Different Wireless Applications
This paper presents the design of a compact microstrip patch antenna with the ability of controlling the number of bands and the operating frequencies independently. Numerical equations are derived using a curve fitting technique to obtain the centre frequency of each band. The antenna comprises a main patch and four sub-patches fed by a 50 microstrip line. It is designed to generate up to five separate modes to cover the frequency range from 900MHz to 3GHz for the operation of wireless devices supporting multiple standards including Global System for Mobile communication (GSM900, 880-960 MHz), Digital Communication System (DCS1800, 1710-1880 MHz), Universal Mobile Telecommunication System (UMTS, 1920-2170 MHz), Wireless Local Area Network (WLAN, 2400-2483.5 MHz) and low band Worldwide Interoperability for Microwave Access (WIMAX, 2.5 to 2.8 GHz).NPL SMART chamber were supported by the Measurements for Innovators (MFI) program and the National Measurement Office, an Executive Agency of the Department for Business, Innovation and Skill
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Evaluating theories of liberal hegemony and small states in U.S.-Jordanian relations since 2000
The present thesis takes as its main object of study the features and solidity of U.S.- Jordanian relations in the 2000s. While the power disparity between the U.S.A, as the sole superpower in the current international system, and Jordan, as a small state, is undeniably huge, it is claimed that the relations between the two countries are rather power relations, especially during the unprecedented era of U.S. power and unilateralism during President G.W. Bushâs two terms. This thesis, however, argues that these relations between the two countries are better explained by attributing a level of a mutually agreed relative autonomy to the weaker side, Jordan
The revised short-form of the Eating Beliefs Questionnaire: Measuring positive, negative, and permissive beliefs about binge eating.
BACKGROUND: The Eating Beliefs Questionnaire (EBQ) is a self-report assessment tool that measures positive and negative beliefs about food and eating that are believed to play a key role in maintaining binge eating behaviour that occurs in individuals with Bulimia Nervosa, Binge Eating Disorder and other atypical eating disorders. The present study aimed to further refine this measure with the addition of a third scale to assess permissive beliefs about eating, also thought to play a crucial role in the maintenance of binge eating. Permissive beliefs are defined as beliefs about eating that provide justification for the individual to engage in a binge eating episode. METHODS: After consultation with the literature and endorsement from 10 experts in eating disorders, 19 permissive belief items were generated. Eight hundred eighty-three participants were recruited to complete a test battery online that included the EBQ and the new permissive items. RESULTS: An exploratory factor analysis (nâ=â441) found a three-factor solution (positive, negative and permissive beliefs) explaining 63.4% of variance. A confirmatory factor analysis (nâ=â442) provided support for the three-factor model, with the data best supporting a shorter 18-item questionnaire. The revised scale demonstrated good internal consistency, as well as good convergent validity with measures of related eating disorder symptoms, emotional regulation, mood and anxiety. CONCLUSIONS: With the addition of a third scale to measure permissive beliefs, the revised short-form of the EBQ offers clinicians and researchers a brief comprehensive tool for the measurement of positive, negative and permissive beliefs about binge eating
Processes and pathways to binge eating: development of an integrated cognitive and behavioural model of binge eating.
Background:There are a number of factors commonly believed to be important to the development and maintenance of binge eating that have been identified across multiple models and theories in the psychological literature. In the present study, we sought to develop and test a psychological model for binge eating that incorporated the main variables identified in the literature to drive binge eating behaviour; specifically, core low self-esteem, negative affect, difficulty with emotional regulation, restricted eating and beliefs about eating. Methods:Questionnaire data was collected from 760 unselected participants. The proposed model of binge eating was developed, bivariate relationships between the included variables were assessed, and the goodness-of-fit of this new model was evaluated using structural equations modelling. Result:The results identified significant bivariate relationships between all the included variables. While the originally proposed model did not provide a good fit to the data, the revised version of the model provided a good fit to the data. Conclusions:Supporting, integrating and building upon the current existing psychological models of binge eating, this study presents a new integrated cognitive and behavioural model of binge eating. The dual-pathway to binge eating identified in the new model provides a different way to understand transdiagnostic binge eating
Case Report: Senior-Loken syndrome: A novel NPHP5 gene mutation in a family from Kuwait
Background: Rare autosomal recessive disorders of variable severity are segregating in many highly consanguineous families from the Arab population. One of these deleterious diseases is Senior-Loken syndrome, a hereditary heterogeneous multiorgan disorder, which combines nephronophthisis with retinal dystrophy, leading to blindness and eventually end stage renal failure. This disorder has been reported in many cases worldwide, including two unrelated families from Arabian Gulf countries, which share the gene pool with Kuwait.Case report: Here, we are reporting two children from an Arab family with a novel frameshift mutation found in IQCB1/NPHP5 gene; c.1241-1242delTC, predicted to cause protein termination p.Leu414HisfsStop4, and describing the associated clinical features.Conclusion: Identification of this pathogenic mutation helped in confirmation of the clinical diagnosis and in providing a proper pre-marital genetic counselling and testing for a couple embarking on marriage from this highly consanguineous high-risk family.Keywords: Arab; Ciliopathy; Consanguinity; Nephronophthisis; Senior-Loken syndrome; Premarital counsellin
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HP1 reshapes nucleosome core to promote phase separation of heterochromatin
Heterochromatin affects genome function at many levels. It enables heritable gene repression, maintains chromosome integrity and provides mechanical rigidity to the nucleus1,2. These diverse functions are proposed to arise in part from compaction of the underlying chromatin2. A major type of heterochromatin contains at its core the complex formed between HP1 proteins and chromatin that is methylated on histone H3, lysine 9 (H3K9me). HP1 is proposed to use oligomerization to compact chromatin into phase-separated condensates3-6. Yet, how HP1-mediated phase separation relates to chromatin compaction remains unclear. Here we show that chromatin compaction by the Schizosaccharomyces pombe HP1 protein Swi6 results in phase-separated liquid condensates. Unexpectedly, we find that Swi6 substantially increases the accessibility and dynamics of buried histone residues within a nucleosome. Restraining these dynamics impairs compaction of chromatin into liquid droplets by Swi6. Our results indicate that Swi6 couples its oligomerization to the phase separation of chromatin by a counterintuitive mechanism, namely the dynamic exposure of buried nucleosomal regions. We propose that such reshaping of the octamer core by Swi6 increases opportunities for multivalent interactions between nucleosomes, thereby promoting phase separation. This mechanism may more generally drive chromatin organization beyond heterochromatin
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