194 research outputs found

    Chromaticity dependence of the transverse effective impedance in the CERN Proton Synchrotron

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    The current knowledge of the transverse beam coupling impedance of the CERN Proton Synchrotron (PS) has been established with beam-based measurements at different energies. The transverse coherent tune shift as a function of the beam intensity has been measured in order to evaluate the total effective imaginary part of the transverse impedance in the accelerator at the energies of 7, 13 and 25 GeV. Measurements have been performed changing the vertical chromaticity for each vertical tune scan with intensity. The data analysis revealed an increase of impedance with chromaticity for all the considered energies. The transverse impedance can be compared with the previously evaluated theoretical impedance budget taking into account the individual contribution of several machine devices

    Baseline LHC machine parameters and configuration of the 2015 proton run

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    This paper shows the baseline LHC machine parameters for the 2015 start-up. Many systems have been upgraded during LS1 and in 2015 the LHC will operate at a higher energy than before and with a tighter filling scheme. Therefore, the 2015 commissioning phase risks to be less smooth than in 2012. The proposed starting configuration puts the focus on feasibility rather than peak performance and includes margins for operational uncertainties. Instead, once beam experience and a better machine knowledge has been obtained, a push in β\beta^* and performance can be envisaged. In this paper, the focus is on collimation settings and reach in β\beta^*---other parameters are covered in greater depth by other papers in these proceedings.Comment: submitted for publication in a CERN yellow report (Proceedings of the LHC Performance Workshop - Chamonix 2014

    Status of LHC Crab Cavity simulations and beam studies

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    The LHC crab cavity program is advancing rapidly towards a first prototype which is anticipated to be tested during the early stages of the LHC phase I upgrade and commissioning. The general project status and some aspects related to crab optics, collimation, aperture constraints, impedances, noise effects, beam transparency and machine protection critical for a safe and robust operation of LHC beams with crab cavities are addressed here

    The UA9 experimental layout

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    The UA9 experimental equipment was installed in the CERN-SPS in March '09 with the aim of investigating crystal assisted collimation in coasting mode. Its basic layout comprises silicon bent crystals acting as primary collimators mounted inside two vacuum vessels. A movable 60 cm long block of tungsten located downstream at about 90 degrees phase advance intercepts the deflected beam. Scintillators, Gas Electron Multiplier chambers and other beam loss monitors measure nuclear loss rates induced by the interaction of the beam halo in the crystal. Roman pots are installed in the path of the deflected particles and are equipped with a Medipix detector to reconstruct the transverse distribution of the impinging beam. Finally UA9 takes advantage of an LHC-collimator prototype installed close to the Roman pot to help in setting the beam conditions and to analyze the efficiency to deflect the beam. This paper describes in details the hardware installed to study the crystal collimation during 2010.Comment: 15pages, 11 figure, submitted to JINS

    Rivastigmine decreases brain damage in HIV patients with mild cognitive deficits.

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    Rivastigmine has been shown to improve cognition in HIV+ patients with minor neurocognitive disorders; however, the mechanisms underlying such beneficial effect are currently unknown. To assess whether rivastigmine therapy is associated with decreased brain inflammation and damage, we performed T1/T2* relaxometry and magnetization transfer imaging in 17 aviremic HIV+ patients with minor neurocognitive disorders enrolled on a crossed over randomized rivastigmine trial. Rivastigmine therapy was associated with changes in MRI metrics indicating a decrease in brain water content (i.e., edema reabsorption) and/or reduced demyelination/axonal damage. Furthermore, MRI changes correlated with cognitive improvement on rivastigmine therapy
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