457 research outputs found

    LA EVOLUCIÓN DE LAS PERSPECTIVAS DE MEDICIÓN DE LA POBREZA

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    This essay refers to the measurement of poverty in the one-dimensional perspective, based on the income, and the conceptual developments that made possible the structuring of a look multidimensional interpretation of socioeconomic phenomena related to deprivation, mainly in the perspective proposed by Amartya Sen, the Approach of Capacities, split into the Human Development Index (HDI) and the Poverty Index Multidimensional (IPM).Este ensayo se refiere a medición de la pobreza en la perspectiva unidimensional, basada en el ingreso, y las evoluciones conceptuales que viabilizaron la estructuración de una mirada multidimensional de interpretación de los fenómenos socioeconómicos relacionados con la privación, principalmente en la perspectiva propuesta por Amartya Sen, el Enfoque de las Capacidades, desdoblado en el Índice de Desarrollo Humano (IDH) y en el Índice de Pobreza Multidimensional (IPM)

    Rizo tomia e discectomia endoscópica no tratamento da dor lombar crônica e radiculopatia aguda na síndrome da pessoa rígida- relato de caso

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    Introduction: Stiff Person Syndrome (SPS) is a rare neurological disorder, first described in 1956 by Moersch and Woltman. The clinical picture has an insidious onset of classic findings of episodic painful spasms, hyperreflexia, axial muscle stiffness, progressing slowly to the proximal limb muscles. Painful hyperlordosis due to lumbar spine stiffness is a diagnostic characteristic of SPS. CASE REPORT: Male, 69 years old, with SPS for 40 years, referred by the neurologist to the spine surgeon because of failure to conservative management of chronic low back pain, progressively acute leg and gait impairment.  Physical examination is difficult to perform in SPS because it triggers spasms. MRI presented zygoapophyseal joint, intervertebral discs and muscle degeneration, including a L4L5 cranial migrated herniated disc. Once there were no other effective ways to manage his axial and radicular pain, it was decided to perform percutaneous transforaminal endoscopic discectomy for L4L5 decompression, L3 to S1 dorsal ganglion root medial branch ablative radiofrequency rhizotomy to relieve facet pain and L2 dorsal sensory ganglion pulsed radiofrequency rhizotomy for modulation of chronic low back pain. One year postoperative follow up, the patient has showed improvement in the VAS and SF-36. CONCLUSION: Chronic pain reported by a patient must be addressed in the biological, psychological and social dimensions. Understanding the multidimensionality of the factors involved with pain allows planning less aggressive and highly efficient strategies in uncommon and off label patients, as in the case of SPS.Introdução: A síndrome da pessoa rígida (SPR) é um distúrbio neurológico raro, descrito pela primeira vez em 1956 por Moersch e Woltman. O quadro clínico apresenta início insidioso de achados clássicos de espasmos dolorosos episódicos, hiperreflexia, rigidez muscular axial, progredindo lentamente para os músculos proximais dos membros. A hiperlordose dolorosa devido à rigidez da coluna lombar é uma característica diagnóstica do SPS. RELATO DO CASO: Homem, 69 anos, com SPS há 40 anos, encaminhado pelo neurologista ao cirurgião de coluna por falha no manejo conservador da lombalgia crônica, dor radicular progressivo na perna e alteração da marcha. O exame físico é difícil de realizar na SPR porque desencadeia espasmos. A ressonância magnética apresentou degeneração nas articulações zigapofisárias, nos discos intervertebrais e muscular, incluindo hérnia discal L4L5 com migração cranial. Uma vez que não havia outras maneiras eficazes de gerenciar sua dor axial e radicular, foi decidido realizar discectomia endoscópica transforaminal percutânea para descompressão de L4L5, rizotomia de radiofrequência ablativa do ramo medial do gânglio dorsal de L3 a S1 para aliviar a dor facetaria e rizotomia de radiofrequência pulsada do gânglio sensitivo dorsal L2 para modulação da dor lombar crônica. Após um ano de pós-operatório, o paciente apresentou melhora na EVA e no SF-36. CONCLUSÃO: A dor crônica relatada pelo paciente deve ser tratada nas dimensões biológica, psicológica e social. Compreender a multidimensionalidade dos fatores envolvidos com a dor permite planejar estratégias menos agressivas e altamente eficientes em pacientes incomuns e off label, como no caso do SPS

    Sarcopenia and risk of malnutrition as risk factors for complications from COVID-19

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    Objetivo: Este estudo teve como objetivo associar o risco nutricional e de sarcopenia com desfechos clínicos em pacientes idosos com COVID-19. Métodos: Trata-se de um estudo de coorte retrospectivo longitudinal. Idosos hospitalizados com diagnóstico de COVID-19 foram incluídos no estudo. O risco nutricional foi avaliado usando o Malnutrition Universal Screening Tool (MUST) e o risco de sarcopenia foi avaliado usando o SARC-F. As associações foram avaliadas por modelos logísticos multivariados. Resultados: No total, 127 pacientes (média de idade: 71,25 ±8,06 anos) foram acompanhados até o desfecho clínico. Risco de sarcopenia foi diagnosticado em 63,8% da amostra, enquanto risco nutricional foi observado em 72% deles. Além disso, 48,8% da amostra necessitoude internação em unidade de terapia intensiva (UTI), 38,6% necessitaram ventilação mecânica e 32,3% foram a óbito. Idosos com risco de sarcopenia tiveram maior chance de internação em UTI (OR: 5,62; IC 95%: 2,2-14,3), necessidade de ventilação mecânica (OR: 4,0; IC 95%: 1,5-10,2) e óbito (OR: 5,06; IC 95%: 1,7-14,2). O risco de desnutrição avaliado pelo MUST foi um importante fator de risco para óbito (OR = 30,15; IC 95%: 3,6-245,8; p<0,01). Conclusão: O risco de sarcopenia foi fator de risco para óbito, internação em UTI e ventilação mecânica,enquanto o risco nutricional foi fator de risco para óbito.Purpose: This study aimed to associate nutritional and sarcopenia risk with clinical outcomes in elderly patients with COVID-19. Methods: This is a longitudinal retrospective cohort study. Hospitalized elderly individuals diagnosed with COVID-19 were included in the study. Nutritional risk was assessed using the Malnutrition Universal Screening Tool (MUST), and Sarcopenia risk was assessed using the SARC-F. Associations were assessed throughmultivariable logistic models. Results: In total, 127 patients (mean age: 71.25 ±8.06 years) were followed up until the clinical outcome. Sarcopenia risk was diagnosed in 63.8% of the sample, whereas nutritional risk was observed in 72%. Hospitalization in the intensive care unit (ICU) was required in 48.8% of the sample, 38.6% required mechanicalventilation, and 32.3% died. Elderly individuals with sarcopenia risk were more likely to be hospitalized inICUs (OR: 5.62; 95%CI: 2.2-14.3), require mechanical ventilation (OR: 4.0; 95% CI: 1.5-10.2), and die (OR: 5.06; 95% CI: 1.7-14.2). The risk of malnutrition assessed through MUST was an important risk factor for death (OR = 30.15; 95% CI: 3.6-245.8; p<0.01). Conclusion: Sarcopenia risk was a risk factor for death, hospitalization in ICU, and mechanical ventilation, while nutritional risk was a risk factor for death

    Comparative serology techniques for the diagnosis of Trypanosoma cruzi infection in a rural population from the state of Querétaro, Mexico

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    Immunological diagnostic methods for Trypanosoma cruzi depend specifically on the presence of antibodies and parasitological methods lack sensitivity during the chronic and “indeterminate” stages of the disease. This study performed a serological survey of 1,033 subjects from 52 rural communities in 12 of the 18 municipalities in the state of Querétaro, Mexico. We detected anti-T. cruzi antibodies using the following tests: indirect haemagglutination assay (IHA), indirect immunofluorescence assay (IFA), ELISA and recombinant ELISA (rELISA). We also performed Western blot (WB) analysis using iron superoxide dismutase (FeSOD), a detoxifying enzyme excreted by the parasite, as the antigen. Positive test results were distributed as follows: ELISA 8%, rELISA 6.2%, IFA and IHA 5.4% in both cases and FeSOD 8%. A comparative study of the five tests was undertaken. Sensitivity levels, specificity, positive and negative predictive values, concordance percentage and kappa index were considered. Living with animals, trips to other communities, gender, age, type of housing and symptomatology at the time of the survey were statistically analysed using SPSS software v.11.5. Detection of the FeSOD enzyme that was secreted by the parasite and used as an antigenic fraction in WBs showed a 100% correlation with traditional ELISA tests

    THE EVOLUTION OF TECHNOLOGY IN EDUCATION

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    A tecnologia na educação tem estado fortemente presente nessas últimas décadas. E já tem sido incorporada ao discurso de profissionais da educação, podendo chegar a diversos lugares. Há uma evolução da tecnologia nas instituições educacionais. Para uma evolução educacional, é preciso investimento. Atualmente temos uma carência nos instrumentos de estudo, porém existe uma ideia para quebrar esses paradigmas, de ambos os lados, ainda existe uma falta de amadurecimento dessa ideia. São incluí­das aulas presenciais, a distância e livros-textos em formato PDF. Existem vários tipos de aprendizagem, e podem alcançar todos os ní­veis de graduações distintas. Baseamos nossa pesquisa em cinco artigos anteriores e desenvolvemos um artigo de revisão.The technology in the attention of a scenario was serious in the last decades. And it has already been, founded to the discourse of professionals of education, being able to arrive at many places. There is technology in educational institutions. For an educational recovery it takes investment. "There is a lack in the instruments of study, because there is an idea to break paradigms, on both sides, there is still a lack of maturation of this idea. Can be useful at all levels of distinct rankings based on our research on previous articles, and we have developed a review article

    Instituciones de enseñanza superior de España y Brasil: temática sobre las personas con discapacidad

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    Las discusiones acerca de la población con discapacidades fueron insertadas en los cursos de Ciencias de la Actividad Física y Deporte y Educación Física como forma de atender a las disposiciones acordadas en diferentes documentos legales elaborados a lo largo de discusiones sobre el proceso de inclusión. Este proceso resultó en una mayor participación de ese grupo en otros ámbitos sociales entre ellos el deporte, el ocio y las competiciones. Eso nos llevó a preguntarnos cómo esta temática es abordada en los cursos citados. Para comprender este factor analizamos los planes docentes o programas de asignaturas de dos instituciones, una de Brasil y otra de España, que ofrecen estos cursos y que se destacan por la relevancia en el área en sus países. Observamos que la cantidad de horas de trabajo dedicado a la discusión sobre las personas con discapacidad es prácticamente la misma en los dos países, aunque la institución brasileña ofrezca mayor cantidad de asignaturas. Además notamos que la institución brasileña presenta repeticiones de temas que tratan específicamente de la etiología de la discapacidad. Las lecturas específicas indicadas en los programas pueden ser más diversificadas en algunas asignaturas. Por fin, notamos que apenas las asignaturas con temática específica sobre las personas con discapacidad las abordan. Creemos que los cursos pueden ofrecer más posibilidades de discusión sobre esta población en otras asignaturas, ya que las personas con discapacidad participan activamente de diversos espacios donde los profesionales de la Educación Física actúan

    Zika virus infection in pregnancy: a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia

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    Introduction: Zika virus (ZIKV) infection in pregnancy has been associated with microcephaly and severe neurological damage to the fetus. Our aim is to document the risks of adverse pregnancy and birth outcomes and the prevalence of laboratory markers of congenital infection in deliveries to women experiencing ZIKV infection during pregnancy, using data from European Commission-funded prospective cohort studies in 20 centres in 11 countries across Latin America and the Caribbean. / Methods and analysis: We will carry out a centre-by-centre analysis of the risks of adverse pregnancy and birth outcomes, comparing women with confirmed and suspected ZIKV infection in pregnancy to those with no evidence of infection in pregnancy. We will document the proportion of deliveries in which laboratory markers of congenital infection were present. Finally, we will investigate the associations of trimester of maternal infection in pregnancy, presence or absence of maternal symptoms of acute ZIKV infection and previous flavivirus infections with adverse outcomes and with markers of congenital infection. Centre-specific estimates will be pooled using a two-stage approach. / Ethics and dissemination: Ethical approval was obtained at each centre. Findings will be presented at international conferences and published in peer-reviewed open access journals and discussed with local public health officials and representatives of the national Ministries of Health, Pan American Health Organization and WHO involved with ZIKV prevention and control activities

    Health indicators associated with poor sleep quality among university students

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    Objective To associate the sleep quality of Brazilian undergraduate students with health indicators. Method A cross-sectional study was developed with a random sample of 662 undergraduate students from Fortaleza, Brazil. The demographic data, Pittsburgh Sleep Quality Index and health data indicators (smoking, alcoholism, sedentary lifestyle, nutritional condition and serum cholesterol) were collected through a self-administered questionnaire. Blood was collected at a clinical laboratory. In order to estimate the size of the associations, a Poisson Regression was used. Results For students who are daily smokers, the occurrence of poor sleep was higher than in non-smokers (p<0.001). Prevalence rate values were nevertheless close to 1. Conclusion The likelihood of poor sleep is almost the same in smokers and in alcoholics

    Budget impact analysis of medicines : updated systematic review and implications

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    This evaluation determines whether published studies to date meet the key characteristics identified for budget impact analyses (BIA) for medicines, accomplished through a systematic review and assessment against identified key characteristics. Studies from 2001 to 2015 on "budget impact analysis" with "drug" interventions were assessed, selected based on their titles/abstracts and full texts, with their characteristics checked according to key criteria. Out of 1984 studies, 92 were identified. Of these, 95% were published in Europe and the USA. 2012 saw the largest number of publications (16%) with a decline thereafter. 48% met up to 6 or 7 out of the 9 key characteristics. Only 22% stated no conflict of interest. The results indicate low adherence to the key characteristics that should be considered for BIAs and strong conflict of interest. This is an issue since BIAs can be of fundamental importance in managing the entry of new medicines including reimbursement decisions
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