446 research outputs found
Short communication: Short-term effect of 3-nitrooxypropanol on feed dry matter intake in lactating dairy cows
[vasopressin Intravenous Infusion Causes Dose Dependent Adverse Cardiovascular Effects In Anesthetized Dogs].
BACKGROUND: Arginine vasopressin (AVP) has been broadly used in the management of vasodilatory shock. However, there are many concerns regarding its clinical use, especially in high doses, as it can be associated with adverse cardiovascular events. OBJECTIVE: To investigate the cardiovascular effects of AVP in continuous IV infusion on hemodynamic parameters in dogs. METHODS: Sixteen healthy mongrel dogs, anesthetized with pentobarbital were intravascularly catheterized, and randomly assigned to: control (saline-placebo; n=8) and AVP (n=8) groups. The study group was infused with AVP for three consecutive 10-minute periods at logarithmically increasing doses (0.01; 0.1 and 1.0 U/kg/min), at them 20-min intervals. Heart rate (HR) and intravascular pressures were continuously recorded. Cardiac output was measured by the thermodilution method. RESULTS: No significant hemodynamic effects were observed during 0.01 U/kg/min of AVP infusion, but at higher doses (0.1 and 1.0 U/kg/min) a progressive increase in mean arterial pressure (MAP) and systemic vascular resistance index (SVRI) were observed, with a significant decrease in HR and the cardiac index (CI). A significant increase in the pulmonary vascular resistance index (PVRI) was also observed with the 1.0 U/kg/min dose, mainly due to the decrease in the CI. CONCLUSION: AVP, when administered at doses between 0.1 and 1.0 U/kg/min, induced significant increases in MAP and SVRI, with negative inotropic and chronotropic effects in healthy animals. Although these doses are ten to thousand times greater than those routinely used for the management of vasodilatory shock, our data confirm that AVP might be used carefully and under strict hemodynamic monitoring in clinical practice, especially if doses higher than 0.01 U/kg/min are needed.942213218, 229-234, 216-22
Dimensionless cosmology
Although it is well known that any consideration of the variations of
fundamental constants should be restricted to their dimensionless combinations,
the literature on variations of the gravitational constant is entirely
dimensionful. To illustrate applications of this to cosmology, we explicitly
give a dimensionless version of the parameters of the standard cosmological
model, and describe the physics of Big Bang Neucleosynthesis and recombination
in a dimensionless manner. The issue that appears to have been missed in many
studies is that in cosmology the strength of gravity is bound up in the
cosmological equations, and the epoch at which we live is a crucial part of the
model. We argue that it is useful to consider the hypothetical situation of
communicating with another civilization (with entirely different units),
comparing only dimensionless constants, in order to decide if we live in a
Universe governed by precisely the same physical laws. In this thought
experiment, we would also have to compare epochs, which can be defined by
giving the value of any {\it one} of the evolving cosmological parameters. By
setting things up carefully in this way one can avoid inconsistent results when
considering variable constants, caused by effectively fixing more than one
parameter today. We show examples of this effect by considering microwave
background anisotropies, being careful to maintain dimensionlessness
throughout. We present Fisher matrix calculations to estimate how well the fine
structure constants for electromagnetism and gravity can be determined with
future microwave background experiments. We highlight how one can be misled by
simply adding to the usual cosmological parameter set
f(R,L_m) gravity
We generalize the type gravity models by assuming that the
gravitational Lagrangian is given by an arbitrary function of the Ricci scalar
and of the matter Lagrangian . We obtain the gravitational field
equations in the metric formalism, as well as the equations of motion for test
particles, which follow from the covariant divergence of the energy-momentum
tensor. The equations of motion for test particles can also be derived from a
variational principle in the particular case in which the Lagrangian density of
the matter is an arbitrary function of the energy-density of the matter only.
Generally, the motion is non-geodesic, and takes place in the presence of an
extra force orthogonal to the four-velocity. The Newtonian limit of the
equation of motion is also considered, and a procedure for obtaining the
energy-momentum tensor of the matter is presented. The gravitational field
equations and the equations of motion for a particular model in which the
action of the gravitational field has an exponential dependence on the standard
general relativistic Hilbert--Einstein Lagrange density are also derived.Comment: 6 pages, no figures; minor modifications, references added; accepted
for publication in EPJ
Effects of chromium supplementation on the infrapopulations of Anacanthorus penilabiatus (Monogenoidea) and Piscinoodinium pillulare (Dinoflagellida) parasites of Piaractus mesopotamicus (Characidae)
Level Set Method for the Evolution of Defect and Brane Networks
A theory for studying the dynamic scaling properties of branes and
relativistic topological defect networks is presented. The theory, based on a
relativistic version of the level set method, well-known in other contexts,
possesses self-similar ``scaling'' solutions, for which one can calculate many
quantities of interest. Here, the length and area densities of cosmic strings
and domain walls are calculated in Minkowski space, and radiation, matter, and
curvature-dominated FRW cosmologies with 2 and 3 space dimensions. The scaling
exponents agree the naive ones based on dimensional analysis, except for cosmic
strings in 3-dimensional Minkowski space, which are predicted to have a
logarithmic correction to the naive scaling form. The scaling amplitudes of the
length and area densities are a factor of approximately 2 lower than results
from numerical simulations of classical field theories. An expression for the
length density of strings in the condensed matter literature is corrected.Comment: 46pp LaTeX, revtex4(preprint), 1 eps figure, revised for publication.
Note title chang
Microbiological profile of donor corneas stored for tectonic transplantation purposes in rabbits
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