Class II treatment by palatal miniscrew-system appliance: A case report

This case shows that using a rapid palatal expander (RPE) and then a pendulum appliance anchored to palatal miniscrews is an option for improving treatment management in a noncompliant patient requiring maxillary expansion and molar distalization in the late mixed dentition. First, an RPE was used to expand the maxillary arch. Then, a modified pendulum appliance was used to distalize the maxillary first permanent molars. Optimal positioning of two palatal miniscrews enabled both appliances to be supported by skeletal anchorage. Treatment was finished using multibracket fixed appliances, and after 2 years, skeletal Class I as well as dental Class I canine and molar relationships were achieved

Characterization of the Hamamatsu R11265-103-M64 multi-anode photomultiplier tube

The aim of this paper is to fully characterize the new multi-anode photomultiplier tube R11265-103-M64, produced by Hamamatsu. Its high effective active area (77%), its pixel size, the low dark signal rate and the capability to detect single photon signals make this tube suitable for an application in high energy physics, such as for RICH detectors. Four tubes and two different bias voltage dividers have been tested. The results of a standard characterization of the gain and the anode uniformity, the dark signal rate, the cross-talk and the device behaviour as a function of temperature have been studied. The behaviour of the tube is studied in a longitudinal magnetic field up to 100 Gauss. Shields made of a high permeability material are also investigated. The deterioration of the device performance due to long time operation at intense light exposure is studied. A quantitative analysis of the variation of the gain and the dark signals rate due to the aging is described.Comment: 22 page

Effect of Fourier filters in removing periodic systematic effects from CMB data

We consider the application of high-pass Fourier filters to remove periodic systematic fluctuations from full-sky survey CMB datasets. We compare the filter performance with destriping codes commonly used to remove the effect of residual 1/f noise from timelines. As a realistic working case, we use simulations of the typical Planck scanning strategy and Planck Low Frequency Instrument noise performance, with spurious periodic fluctuations that mimic a typical thermal disturbance. We show that the application of Fourier high-pass filters in chunks always requires subsequent normalisation of induced offsets by means of destriping. For a complex signal containing all the astrophysical and instrumental components, the result obtained by applying filter and destriping in series is comparable to the result obtained by destriping only, which makes the usefulness of Fourier filters questionable for removing this kind of effects.Comment: 10 pages, 8 figures, published in Astronomy & Astrophysic

A new approach to the front-end readout of cryogenic ionization detectors

We present a novel approach to the readout of ionization detectors. The solution allows to minimize the number of components and the space occupation close to the detector. This way a minimal impact is added on the radioactive background in those experiments where very low signal rates are expected, such as GERDA and MAJORANA. The circuit consists in a JFET transistor and a remote second stage. The DC feedback path is closed using a diode. Two signal cables are only necessary for biasing and readout.Comment: 14 pages, 15 figures and 15 equation

Large area Si low-temperature light detectors with Neganov-Luke effect

Next generation calorimetric experiments for the search of rare events rely on the detection of tiny amounts of light (of the order of 20 optical photons) to discriminate and reduce background sources and improve sensitivity. Calorimetric detectors are the simplest solution for photon detection at cryogenic (mK) temperatures. The development of silicon based light detectors with enhanced performance thanks to the use of the Neganov-Luke effect is described. The aim of this research line is the production of high performance detectors with industrial-grade reproducibility and reliability.Comment: 4 pages, 2 figure

A bioclinical pattern for the early diagnosis of cardioembolic stroke

Background and Scope. Early etiologic diagnosis of ischemic stroke subtype guides acute management and treatment. We aim to evaluate if plasma biomarkers can predict stroke subtypes in the early phase from stroke onset. Methods. Plasma N-terminal prohormone of brain natriuretic peptide (NT-proBNP), D-dimer, C-reactive protein, serum albumin, and globulin levels have been investigated in 114 consecutive patients presenting at the emergency room within 6 hours of the ischemic stroke onset. Plasma levels of biomarkers have been correlated with stroke aetiology (based on TOAST criteria) by multivariable logistic regression analysis, adjusted for several covariates. Results. Of the 114 patients, 34 (30%) had cardioembolic stroke, 27 (23%) atherothrombotic stroke, 19 (17%) lacunar stroke, and 34 (30%) stroke of undetermined origin. Patients with cardioembolic stroke had significantly higher levels of NT-proBNP and lower globulin/albumin (G/A) ratio compared with the other subgroups. At multiple logistic regression NT-proBN \u2009pg/mL, G/A rati and NIHSS score were independent predictors of cardioembolic stroke with high accuracy of the model, either including (AUC, 0.91) or excluding (AUC, 0.84) atrial fibrillation. Conclusions. A prediction model that includes NT-proBNP, G/A ratio, and NIHSS score can be useful for the early etiologic diagnosis of ischemic stroke

Map-making in small field modulated CMB polarisation experiments: approximating the maximum-likelihood method

Map-making presents a significant computational challenge to the next generation of kilopixel CMB polarisation experiments. Years worth of time ordered data (TOD) from thousands of detectors will need to be compressed into maps of the T, Q and U Stokes parameters. Fundamental to the science goal of these experiments, the observation of B-modes, is the ability to control noise and systematics. In this paper, we consider an alternative to the maximum-likelihood method, called destriping, where the noise is modelled as a set of discrete offset functions and then subtracted from the time-stream. We compare our destriping code (Descart: the DEStriping CARTographer) to a full maximum-likelihood map-maker, applying them to 200 Monte-Carlo simulations of time-ordered data from a ground based, partial-sky polarisation modulation experiment. In these simulations, the noise is dominated by either detector or atmospheric 1/f noise. Using prior information of the power spectrum of this noise, we produce destriped maps of T, Q and U which are negligibly different from optimal. The method does not filter the signal or bias the E or B-mode power spectra. Depending on the length of the destriping baseline, the method delivers between 5 and 22 times improvement in computation time over the maximum-likelihood algorithm. We find that, for the specific case of single detector maps, it is essential to destripe the atmospheric 1/f in order to detect B-modes, even though the Q and U signals are modulated by a half-wave plate spinning at 5-Hz.Comment: 18 pages, 17 figures, MNRAS accepted v2: content added (inc: table 2), typos correcte

Neural networks and separation of Cosmic Microwave Background and astrophysical signals in sky maps

The Independent Component Analysis (ICA) algorithm is implemented as a neural network for separating signals of different origin in astrophysical sky maps. Due to its self-organizing capability, it works without prior assumptions on the signals, neither on their frequency scaling, nor on the signal maps themselves; instead, it learns directly from the input data how to separate the physical components, making use of their statistical independence. To test the capabilities of this approach, we apply the ICA algorithm on sky patches, taken from simulations and observations, at the microwave frequencies, that are going to be deeply explored in a few years on the whole sky, by the Microwave Anisotropy Probe (MAP) and by the {\sc Planck} Surveyor Satellite. The maps are at the frequencies of the Low Frequency Instrument (LFI) aboard the {\sc Planck} satellite (30, 44, 70 and 100 GHz), and contain simulated astrophysical radio sources, Cosmic Microwave Background (CMB) radiation, and Galactic diffuse emissions from thermal dust and synchrotron. We show that the ICA algorithm is able to recover each signal, with precision going from 10% for the Galactic components to percent for CMB; radio sources are almost completely recovered down to a flux limit corresponding to $0.7\sigma_{CMB}$, where $\sigma_{CMB}$ is the rms level of CMB fluctuations. The signal recovering possesses equal quality on all the scales larger then the pixel size. In addition, we show that the frequency scalings of the input signals can be partially inferred from the ICA outputs, at the percent precision for the dominant components, radio sources and CMB.Comment: 15 pages; 6 jpg and 1 ps figures. Final version to be published in MNRA

Scientific optimization of a ground-based CMB polarization experiment

We investigate the science goals achievable with the upcoming generation of ground-based Cosmic Microwave Background polarization experiments and calculate the optimal sky coverage for such an experiment including the effects of foregrounds. We find that with current technology an E-mode measurement will be sample-limited, while a B-mode measurement will be detector-noise-limited. We conclude that a 300 sq deg survey is an optimal compromise for a two-year experiment to measure both E and B-modes, and that ground-based polarization experiments can make an important contribution to B-mode surveys. Focusing on one particular experiment, QUaD, a proposed bolometric polarimeter operating from the South Pole, we find that a ground-based experiment can make a high significance measurement of the acoustic peaks in the E-mode spectrum, and will be able to detect the gravitational lensing signal in the B-mode spectrum. Such an experiment could also directly detect the gravitational wave component of the B-mode spectrum if the amplitude of the signal is close to current upper limits. We also investigate how a ground-based experiment can improve constraints on the cosmological parameters. We estimate that by combining two years of QUaD data with the four-year WMAP data, an optimized ground-based polarization experiment can improve constraints on cosmological parameters by a factor of two. If the foreground contamination can be reduced, the measurement of the tensor-to-scalar ratio can be improved by up to a factor of six over that obtainable from WMAP alone.Comment: 17 pages, 11 figures replaced with version accepted by MNRA

SANEPIC: A Map-Making Method for Timestream Data From Large Arrays

We describe a map-making method which we have developed for the Balloon-borne Large Aperture Submillimeter Telescope (BLAST) experiment, but which should have general application to data from other submillimeter arrays. Our method uses a Maximum Likelihood based approach, with several approximations, which allows images to be constructed using large amounts of data with fairly modest computer memory and processing requirements. This new approach, Signal And Noise Estimation Procedure Including Correlations (SANEPIC), builds upon several previous methods, but focuses specifically on the regime where there is a large number of detectors sampling the same map of the sky, and explicitly allowing for the the possibility of strong correlations between the detector timestreams. We provide real and simulated examples of how well this method performs compared with more simplistic map-makers based on filtering. We discuss two separate implementations of SANEPIC: a brute-force approach, in which the inverse pixel-pixel covariance matrix is computed; and an iterative approach, which is much more efficient for large maps. SANEPIC has been successfully used to produce maps using data from the 2005 BLAST flight.Comment: 27 Pages, 15 figures; Submitted to the Astrophysical Journal; related results available at http://blastexperiment.info/ [the BLAST Webpage