1,950 research outputs found
Imaging and controlling electron transport inside a quantum ring
Traditionally, the understanding of quantum transport, coherent and
ballistic1, relies on the measurement of macroscopic properties such as the
conductance. While powerful when coupled to statistical theories, this approach
cannot provide a detailed image of "how electrons behave down there". Ideally,
understanding transport at the nanoscale would require tracking each electron
inside the nano-device. Significant progress towards this goal was obtained by
combining Scanning Probe Microscopy (SPM) with transport measurements2-7. Some
studies even showed signatures of quantum transport in the surrounding of
nanostructures4-6. Here, SPM is used to probe electron propagation inside an
open quantum ring exhibiting the archetype of electron wave interference
phenomena: the Aharonov-Bohm effect8. Conductance maps recorded while scanning
the biased tip of a cryogenic atomic force microscope above the quantum ring
show that the propagation of electrons, both coherent and ballistic, can be
investigated in situ, and even be controlled by tuning the tip potential.Comment: 11 text pages + 3 figure
A unifying framework for seed sensitivity and its application to subset seeds
We propose a general approach to compute the seed sensitivity, that can be
applied to different definitions of seeds. It treats separately three
components of the seed sensitivity problem -- a set of target alignments, an
associated probability distribution, and a seed model -- that are specified by
distinct finite automata. The approach is then applied to a new concept of
subset seeds for which we propose an efficient automaton construction.
Experimental results confirm that sensitive subset seeds can be efficiently
designed using our approach, and can then be used in similarity search
producing better results than ordinary spaced seeds
The Presence of Weak Active Galactic Nuclei in High Redshift Star Forming Galaxies
We present [OIII 5007A] observations of the star forming galaxy HDF-BMZ1299
(z=1.598) using Keck Observatory's Adaptive Optics system with the
near-infrared integral field spectrograph OSIRIS. Using previous Halpha and
[NII] measurements of the same source, we are able for the first time to use
spatially resolved observations to place a high-redshift galaxy's substructure
on a traditional HII diagnostic diagram. We find that HDF-BMZ1299's spatially
concentrated nebular ratios in the central ~1.5 kiloparsec (0."2) are best
explained by the presence of an AGN: log([NII]/Halpha)=-0.22+/-0.05 and 2sigma
limit of log([OIII]/Hbeta)>0.26. The dominant energy source of this galaxy is
star formation, and integrating a single aperture across the galaxy yields
nebular ratios that are composite spectra from both AGN and HII regions. The
presence of an embedded AGN in HDF-BMZ1299 may suggest a potential
contamination in a fraction of other high-redshift star forming galaxies, and
we suggest that this may be a source of the "elevated" nebular ratios
previously seen in seeing-limited metallicity studies. HDF-BMZ1299's estimated
AGN luminosity is L_Halpha = 3.7e41 erg/s and L_[OIII] = 5.8e41 erg/s, making
it one of the lowest luminosity AGN discovered at this early epoch.Comment: 15 pages, 4 figures, ApJ Accepted, new version to be published
(updated text, figures, and table
The physics of Lyman α escape from high-redshift galaxies
Lyman α (Lyα) photons from ionizing sources and cooling radiation undergo a complex resonant scattering process that generates unique spectral signatures in high-redshift galaxies. We present a detailed Lyα radiative transfer study of a cosmological zoom-in simulation from the Feedback In Realistic Environments (FIRE) project. We focus on the time, spatial, and angular properties of the Lyα emission over a redshift range of z = 5–7, after escaping the galaxy and being transmitted through the intergalactic medium (IGM). Over this epoch, our target galaxy has an average stellar mass of M⋆ ≈ 5×10^8M⊙ .We find that many of the interesting features of the Lyα line can be understood in terms of the galaxy’s star formation history. The time variability, spatial morphology, and anisotropy of Lyα properties are consistent with current observations. For example, the rest-frame equivalent width has an EW_(Lyα,0) > 20˚A duty cycle of 62 per cent with a non-negligible number of sightlines with >100˚A, associated with outflowing regions of a starburst with greater coincident UV continuum absorption, as these conditions generate redder, narrower (or single-peaked) line profiles. The lowest equivalent widths correspond to cosmological filaments, which have little impact on UV continuum photons but efficiently trap Lyα and produce bluer, broader lines with less transmission through the IGM. We also show that in dense self-shielding, low-metallicity filaments and satellites, Lyα radiation pressure can be dynamically important. Finally, despite a significant reduction in surface brightness with increasing redshift, Lyα detections and spectroscopy of high-z galaxies with the upcoming James Webb Space Telescope is feasible
Quantum Phase Transition in a Resonant Level Coupled to Interacting Leads
An interacting one-dimensional electron system, the Luttinger liquid, is
distinct from the "conventional" Fermi liquids formed by interacting electrons
in two and three dimensions. Some of its most spectacular properties are
revealed in the process of electron tunneling: as a function of the applied
bias or temperature the tunneling current demonstrates a non-trivial power-law
suppression. Here, we create a system which emulates tunneling in a Luttinger
liquid, by controlling the interaction of the tunneling electron with its
environment. We further replace a single tunneling barrier with a
double-barrier resonant level structure and investigate resonant tunneling
between Luttinger liquids. For the first time, we observe perfect transparency
of the resonant level embedded in the interacting environment, while the width
of the resonance tends to zero. We argue that this unique behavior results from
many-body physics of interacting electrons and signals the presence of a
quantum phase transition (QPT). In our samples many parameters, including the
interaction strength, can be precisely controlled; thus, we have created an
attractive model system for studying quantum critical phenomena in general. Our
work therefore has broadly reaching implications for understanding QPTs in more
complex systems, such as cold atoms and strongly correlated bulk materials.Comment: 11 pages total (main text + supplementary
Average and extreme multi-atom Van der Waals interactions: Strong coupling of multi-atom Van der Waals interactions with covalent bonding
<p>Abstract</p> <p>Background</p> <p>The prediction of ligand binding or protein structure requires very accurate force field potentials – even small errors in force field potentials can make a 'wrong' structure (from the billions possible) more stable than the single, 'correct' one. However, despite huge efforts to optimize them, currently-used all-atom force fields are still not able, in a vast majority of cases, even to keep a protein molecule in its native conformation in the course of molecular dynamics simulations or to bring an approximate, homology-based model of protein structure closer to its native conformation.</p> <p>Results</p> <p>A strict analysis shows that a specific coupling of multi-atom Van der Waals interactions with covalent bonding can, in extreme cases, increase (or decrease) the interaction energy by about 20–40% at certain angles between the direction of interaction and the covalent bond. It is also shown that on average multi-body effects decrease the total Van der Waals energy in proportion to the square root of the electronic component of dielectric permittivity corresponding to dipole-dipole interactions at small distances, where Van der Waals interactions take place.</p> <p>Conclusion</p> <p>The study shows that currently-ignored multi-atom Van der Waals interactions can, in certain instances, lead to significant energy effects, comparable to those caused by the replacement of atoms (for instance, C by N) in conventional pairwise Van der Waals interactions.</p
A massive, quiescent galaxy at redshift of z=3.717
In the early Universe finding massive galaxies that have stopped forming
stars present an observational challenge as their rest-frame ultraviolet
emission is negligible and they can only be reliably identified by extremely
deep near-infrared surveys. These have revealed the presence of massive,
quiescent early-type galaxies appearing in the universe as early as z2,
an epoch 3 Gyr after the Big Bang. Their age and formation processes have now
been explained by an improved generation of galaxy formation models where they
form rapidly at z3-4, consistent with the typical masses and ages derived
from their observations. Deeper surveys have now reported evidence for
populations of massive, quiescent galaxies at even higher redshifts and earlier
times, however the evidence for their existence, and redshift, has relied
entirely on coarsely sampled photometry. These early massive, quiescent
galaxies are not predicted by the latest generation of theoretical models.
Here, we report the spectroscopic confirmation of one of these galaxies at
redshift z=3.717 with a stellar mass of 1.710 M whose
absorption line spectrum shows no current star-formation and which has a
derived age of nearly half the age of the Universe at this redshift. The
observations demonstrates that the galaxy must have quickly formed the majority
of its stars within the first billion years of cosmic history in an extreme and
short starburst. This ancestral event is similar to those starting to be found
by sub-mm wavelength surveys pointing to a possible connection between these
two populations. Early formation of such massive systems is likely to require
significant revisions to our picture of early galaxy assembly.Comment: 6 pages, 7 figures. This is the final preprint corresponding closely
to the published version. Uploaded 6 months after publication in accordance
with Nature polic
The impact of obesity on time spent with the provider and number of medications managed during office-based physician visits using a cross-sectional, national health survey
<p>Abstract</p> <p>Background</p> <p>Obesity is associated with morbidity, mortality, and increased health care costs. Few studies have examined the impact of obesity on outpatient office visits. The purpose of this study was to determine if outpatient visits by obese persons required more time with the provider and more prescription medication management compared to visits made by non-obese persons.</p> <p>Methods</p> <p>Obesity status was determined for 9,280 patient visits made by persons aged 18 years or older in the 2006 National Ambulatory Medical Care Survey. Multivariate analyses compared obese and non-obese visits, stratified by sex, for duration of the visit and the number of medications mentioned at the visit.</p> <p>Results</p> <p>Average duration of visit was higher among visits with patients determined to be obese. However, these differences were not considered significant after statistical testing. Visits made by obese female patients were significantly more likely to involve more than two prescription medications (OR 1.26, 95% CI 1.05 - 1.51) and visits made by obese male patients were significantly more likely to involve more than two prescription medications (OR 1.46, 95% CI 1.16 - 1.83) as compared to visits made by non-obese patients.</p> <p>Conclusion</p> <p>Time spent with the provider was found to be greater among visits with obese patients, but not significantly different from visits with non-obese patients. The number of medications for each visit was found to be significantly greater for visits where the patient was considered to be obese. Increased time for the visit and increased numbers of medication for each visit translate into increased costs. These findings document the impact of obesity on our health care system and have great implications on medical care cost and planning.</p
Gender-Related Differences in the Prevalence of Cardiovascular Disease Risk Factors and their Correlates in Urban Tanzania.
\ud
Urban areas in Africa suffer a serious problem with dual burden of infectious diseases and emerging chronic diseases such as cardiovascular diseases (CVD) and diabetes which pose a serious threat to population health and health care resources. However in East Africa, there is limited literature in this research area. The objective of this study was to examine the prevalence of cardiovascular disease risk factors and their correlates among adults in Temeke, Dar es Salaam, Tanzania. Results of this study will help inform future research and potential preventive and therapeutic interventions against such chronic diseases. The study design was a cross sectional epidemiological study. A total of 209 participants aged between 44 and 66 years were included in the study. A structured questionnaire was used to evaluate socioeconomic and lifestyle characteristics. Blood samples were collected and analyzed to measure lipid profile and fasting glucose levels. Cardiovascular risk factors were defined using World Health Organization criteria. The age-adjusted prevalence of obesity (BMI > or = 30) was 13% and 35%, among men and women (p = 0.0003), respectively. The prevalence of abdominal obesity was 11% and 58% (p < 0.0001), and high WHR (men: >0.9, women: >0.85) was 51% and 73% (p = 0.002) for men and women respectively. Women had 4.3 times greater odds of obesity (95% CI: 1.9-10.1), 14.2-fold increased odds for abdominal adiposity (95% CI: 5.8-34.6), and 2.8 times greater odds of high waist-hip-ratio (95% CI: 1.4-5.7), compared to men. Women had more than three-fold greater odds of having metabolic syndrome (p = 0.001) compared to male counterparts, including abdominal obesity, low HDL-cholesterol, and high fasting blood glucose components. In contrast, female participants had 50% lower odds of having hypertension, compared to men (95%CI: 0.3-1.0). Among men, BMI and waist circumference were significantly correlated with blood pressure, triglycerides, total, LDL-, and HDL-cholesterol (BMI only), and fasting glucose; in contrast, only blood pressure was positively associated with BMI and waist circumference in women. The prevalence of CVD risk factors was high in this population, particularly among women. Health promotion, primary prevention, and health screening strategies are needed to reduce the burden of cardiovascular disease in Tanzania.\u
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