1/N_c- expansion of the quark condensate at finite temperature

Previously the quark and meson properties in a many quark system at finite temperature have been studied within effective QCD approaches in the Hartree approximation. In the present paper we consider the influence of the mesonic correlations on the quark self-energy and on the quark propagator within a systematic $1/N_c$- expansion. Using a general separable ansatz for the nonlocal interaction, we derive a selfconsistent equation for the $1/N_c$ correction to the quark propagator. For a separable model with cut-off formfactor, we obtain a decrease of the condensate of the order of 20\% at zero temperature. A lowering the critical temperature for the onset of the chiral restoration transition due to the inclusion of mesonic correlations is obtained what seems to be closer to the results from lattice calculations.Comment: 19 pages, REVTeX, 5 figure

Vacuum solutions of the gravitational field equations in the brane world model

We consider some classes of solutions of the static, spherically symmetric gravitational field equations in the vacuum in the brane world scenario, in which our Universe is a three-brane embedded in a higher dimensional space-time. The vacuum field equations on the brane are reduced to a system of two ordinary differential equations, which describe all the geometric properties of the vacuum as functions of the dark pressure and dark radiation terms (the projections of the Weyl curvature of the bulk, generating non-local brane stresses). Several classes of exact solutions of the vacuum gravitational field equations on the brane are derived. In the particular case of a vanishing dark pressure the integration of the field equations can be reduced to the integration of an Abel type equation. A perturbative procedure, based on the iterative solution of an integral equation, is also developed for this case. Brane vacuums with particular symmetries are investigated by using Lie group techniques. In the case of a static vacuum brane admitting a one-parameter group of conformal motions the exact solution of the field equations can be found, with the functional form of the dark radiation and pressure terms uniquely fixed by the symmetry. The requirement of the invariance of the field equations with respect to the quasi-homologous group of transformations also imposes a unique, linear proportionality relation between the dark energy and dark pressure. A homology theorem for the static, spherically symmetric gravitational field equations in the vacuum on the brane is also proven.Comment: 13 pages, no figures, to appear in PR

Solvable Models of Domain Walls in N=1 Supergravity

A class of exactly solvable models of domain walls are worked out in D=4 ${\cal N}=1$ supergravity. We develop a method to embed globally supersymmetric theories with exact BPS domain wall solutions into supergravity, by introducing a gravitationally deformed superpotential. The gravitational deformation is natural in the spirit of maintaining the K\"ahler invariance. The solutions of the warp factor and the Killing spinor are also obtained. We find that three distinct behaviors of warp factors arise depending on the value of a constant term in the superpotential : exponentially decreasing in both sides of the wall, flat in one side and decreasing in the other, and increasing in one side and decreasing in the other. Only the first possibility gives the localized massless graviton zero mode. Models with multi-walls and models with runaway vacua are also discussed.Comment: 10 pages, 3 figures; Misprints in three formulas are correcte

Meson Exchange Currents in (e,e'p) recoil polarization observables

A study of the effects of meson-exchange currents and isobar configurations in $A(\vec{e},e'\vec{p})B$ reactions is presented. We use a distorted wave impulse approximation (DWIA) model where final-state interactions are treated through a phenomenological optical potential. The model includes relativistic corrections in the kinematics and in the electromagnetic one- and two-body currents. The full set of polarized response functions is analyzed, as well as the transferred polarization asymmetry. Results are presented for proton knock-out from closed-shell nuclei, for moderate to high momentum transfer.Comment: 44 pages, 18 figures. Added physical arguments explaining the dominance of OB over MEC, and a summary of differences with previous MEC calculations. To be published in PR

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

Background:Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in FGFR1, FGFR3, FGFR4 and FGFRL1 in the Breast Cancer Association Consortium. Methods:Data were combined from 49 studies, including 53 835 cases and 50 156 controls, of which 89 050 (46 450 cases and 42 600 controls) were of European ancestry, 12 893 (6269 cases and 6624 controls) of Asian and 2048 (1116 cases and 932 controls) of African ancestry. Associations with risk of breast cancer, overall and by disease sub-type, were assessed using unconditional logistic regression. Results:Little evidence of association with breast cancer risk was observed for SNPs in the FGF receptor genes. The strongest evidence in European women was for rs743682 in FGFR3; the estimated per-allele odds ratio was 1.05 (95 confidence interval=1.02-1.09, P=0.0020), which is substantially lower than that observed for SNPs in FGFR2. Conclusion:Our results suggest that common variants in the other FGF receptors are not associated with risk of breast cancer to the degree observed for FGFR2. © 2014 Cancer Research UK

Evidence of Color Coherence Effects in W+jets Events from ppbar Collisions at sqrt(s) = 1.8 TeV

We report the results of a study of color coherence effects in ppbar collisions based on data collected by the D0 detector during the 1994-1995 run of the Fermilab Tevatron Collider, at a center of mass energy sqrt(s) = 1.8 TeV. Initial-to-final state color interference effects are studied by examining particle distribution patterns in events with a W boson and at least one jet. The data are compared to Monte Carlo simulations with different color coherence implementations and to an analytic modified-leading-logarithm perturbative calculation based on the local parton-hadron duality hypothesis.Comment: 13 pages, 6 figures. Submitted to Physics Letters

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

Introduction: Tumor lymphocyte infiltration is associated with clinical response to chemotherapy in estrogen receptor (ER) negative breast cancer. To identify variants in immunosuppressive pathway genes associated with prognosis after adjuvant chemotherapy for ER-negative patients, we studied stage I-III invasive breast cancer patients of European ancestry, including 9,334 ER-positive (3,151 treated with chemotherapy) and 2,334 ER-negative patients (1,499 treated with chemotherapy). Methods: We pooled data from sixteen studies from the Breast Cancer Association Consortium (BCAC), and employed two independent studies for replications. Overall 3,610 single nucleotide polymorphisms (SNPs) in 133 genes were genotyped as part of the Collaborative Oncological Gene-environment Study, in which phenotype and clinical data were collected and harmonized. Multivariable Cox proportional hazard regression was used to assess genetic associations with overall survival (OS) and breast

A connectome of the adult drosophila central brain

The neural circuits responsible for behavior remain largely unknown. Previous efforts have reconstructed the complete circuits of small animals, with hundreds of neurons, and selected circuits for larger animals. Here we (the FlyEM project at Janelia and collaborators at Google) summarize new methods and present the complete circuitry of a large fraction of the brain of a much more complex animal, the fruit fly Drosophila melanogaster. Improved methods include new procedures to prepare, image, align, segment, find synapses, and proofread such large data sets; new methods that define cell types based on connectivity in addition to morphology; and new methods to simplify access to a large and evolving data set. From the resulting data we derive a better definition of computational compartments and their connections; an exhaustive atlas of cell examples and types, many of them novel; detailed circuits for most of the central brain; and exploration of the statistics and structure of different brain compartments, and the brain as a whole. We make the data public, with a web site and resources specifically designed to make it easy to explore, for all levels of expertise from the expert to the merely curious. The public availability of these data, and the simplified means to access it, dramatically reduces the effort needed to answer typical circuit questions, such as the identity of upstream and downstream neural partners, the circuitry of brain regions, and to link the neurons defined by our analysis with genetic reagents that can be used to study their functions. Note: In the next few weeks, we will release a series of papers with more involved discussions. One paper will detail the hemibrain reconstruction with more extensive analysis and interpretation made possible by this dense connectome. Another paper will explore the central complex, a brain region involved in navigation, motor control, and sleep. A final paper will present insights from the mushroom body, a center of multimodal associative learning in the fly brain