193 research outputs found
Decreased integration and information capacity in stroke measured by whole brain models of resting state activity.
While several studies have shown that focal lesions affect the communication between structurally normal regions of the brain, and that these changes may correlate with behavioural deficits, their impact on brain's information processing capacity is currently unknown. Here we test the hypothesis that focal lesions decrease the brain's information processing capacity, of which changes in functional connectivity may be a measurable correlate. To measure processing capacity, we turned to whole brain computational modelling to estimate the integration and segregation of information in brain networks. First, we measured functional connectivity between different brain areas with resting state functional magnetic resonance imaging in healthy subjects (n = 26), and subjects who had suffered a cortical stroke (n = 36). We then used a whole-brain network model that coupled average excitatory activities of local regions via anatomical connectivity. Model parameters were optimized in each healthy or stroke participant to maximize correlation between model and empirical functional connectivity, so that the model's effective connectivity was a veridical representation of healthy or lesioned brain networks. Subsequently, we calculated two model-based measures: 'integration', a graph theoretical measure obtained from functional connectivity, which measures the connectedness of brain networks, and 'information capacity', an information theoretical measure that cannot be obtained empirically, representative of the segregative ability of brain networks to encode distinct stimuli. We found that both measures were decreased in stroke patients, as compared to healthy controls, particularly at the level of resting-state networks. Furthermore, we found that these measures, especially information capacity, correlate with measures of behavioural impairment and the segregation of resting-state networks empirically measured. This study shows that focal lesions affect the brain's ability to represent stimuli and task states, and that information capacity measured through whole brain models is a theory-driven measure of processing capacity that could be used as a biomarker of injury for outcome prediction or target for rehabilitation intervention
Mean-field description of collapsing and exploding Bose-Einstein condensates
We perform numerical simulation based on the time-dependent mean-field
Gross-Pitaevskii equation to understand some aspects of a recent experiment by
Donley et al. on the dynamics of collapsing and exploding Bose-Einstein
condensates of Rb atoms. They manipulated the atomic interaction by an
external magnetic field via a Feshbach resonance, thus changing the repulsive
condensate into an attractive one and vice versa. In the actual experiment they
changed suddenly the scattering length of atomic interaction from positive to a
large negative value on a pre-formed condensate in an axially symmetric trap.
Consequently, the condensate collapses and ejects atoms via explosion. We find
that the present mean-field analysis can explain some aspects of the dynamics
of the collapsing and exploding Bose-Einstein condensates.Comment: 9 Latex pages, 10 ps and eps files, version accepted in Physical
Review A, minor changes mad
Soil organic carbon predictions in Subarctic Greenland by visible–near infrared spectroscopy
Release of carbon from high-latitude soils to the atmosphere may have significant effects on Earth’s climate. In this contribution, we evaluate visible–near-infrared spectroscopy (vis-NIRS) as a time- and cost-efficient tool for assessing soil organic carbon (SOC) concentrations in South Greenland. Soil samples were collected at two sites and analyzed with vis-NIRS. We used partial least square regression (PLS-R) modeling to predict SOC from vis-NIRS spectra referenced against in situ dry combustion measurements. The ability of our approach was validated in three setups: (1) calibration and validation data sets from the same location, (2) calibration and validation data sets from different locations, and (3) the same setup as in (2) with the calibration model enlarged with few samples from the opposite target area. Vis-NIRS predictions were successful in setup 1 (R2 = 0.95, root mean square error of prediction [RMSEP] = 1.80 percent and R2 = 0.82, RMSEP = 0.64 percent). Predictions in setup 2 had higher errors (R2 = 0.90, RMSEP = 7.13 percent and R2 = 0.78, RMSEP = 2.82 percent). In setup 3, the results were again improved (R2 = 0.95, RMSEP = 2.03 percent and R2 = 0.77, RMSEP = 2.14 percent). We conclude that vis-NIRS can obtain good results predicting SOC concentrations across two subarctic ecosystems, when the calibration models are augmented with few samples from the target site. Future efforts should be made toward determination of SOC stocks to constrain soil–atmosphere carbon exchange
Scaling limit of virtual states of triatomic systems
For a system with three identical atoms, the dependence of the wave
virtual state energy on the weakly bound dimer and trimer binding energies is
calculated in a form of a universal scaling function. The scaling function is
obtained from a renormalizable three-body model with a pairwise Dirac-delta
interaction. It was also discussed the threshold condition for the appearance
of the trimer virtual state.Comment: 9 pages, 3 figure
Scaling predictions for radii of weakly bound triatomic molecules
The mean-square radii of the molecules He, HeLi,
HeLi and HeNa are calculated using a three-body model
with contact interactions. They are obtained from a universal scaling function
calculated within a renormalized scheme for three particles interacting through
pairwise Dirac-delta interaction. The root-mean-square distance between two
atoms of mass in a triatomic molecule are estimated to be of de order of
, where is the dimer and the
trimer binding energies, and is a constant (varying from
to ) that depends on the ratio between and . Considering
previous estimates for the trimer energies, we also predict the sizes of
Rubidium and Sodium trimers in atomic traps.Comment: 7 pages, 2 figure
Correlated N-boson systems for arbitrary scattering length
We investigate systems of identical bosons with the focus on two-body
correlations and attractive finite-range potentials. We use a hyperspherical
adiabatic method and apply a Faddeev type of decomposition of the wave
function. We discuss the structure of a condensate as function of particle
number and scattering length. We establish universal scaling relations for the
critical effective radial potentials for distances where the average distance
between particle pairs is larger than the interaction range. The correlations
in the wave function restore the large distance mean-field behaviour with the
correct two-body interaction. We discuss various processes limiting the
stability of condensates. With correlations we confirm that macroscopic
tunneling dominates when the trap length is about half of the particle number
times the scattering length.Comment: 15 pages (RevTeX4), 11 figures (LaTeX), submitted to Phys. Rev. A.
Second version includes an explicit comparison to N=3, a restructured
manuscript, and updated figure
Impacts of Climate Change on indirect human exposure to pathogens and chemicals from agriculture
Objective: Climate change is likely to affect the nature of pathogens and chemicals in the environment and their fate and transport. Future risks of pathogens and chemicals could therefore be very different from those of today. In this review, we assess the implications of climate change for changes in human exposures to pathogens and chemicals in agricultural systems in the United Kingdom and discuss the subsequent effects on health impacts.
Data sources: In this review, we used expert input and considered literature on climate change ; health effects resulting from exposure to pathogens and chemicals arising from agriculture ; inputs of chemicals and pathogens to agricultural systems ; and human exposure pathways for pathogens and chemicals in agricultural systems.
Data synthesis: We established the current evidence base for health effects of chemicals and pathogens in the agricultural environment ; determined the potential implications of climate change on chemical and pathogen inputs in agricultural systems ; and explored the effects of climate change on environmental transport and fate of different contaminant types. We combined these data to assess the implications of climate change in terms of indirect human exposure to pathogens and chemicals in agricultural systems. We then developed recommendations on future research and policy changes to manage any adverse increases in risks.
Conclusions: Overall, climate change is likely to increase human exposures to agricultural contaminants. The magnitude of the increases will be highly dependent on the contaminant type. Risks from many pathogens and particulate and particle-associated contaminants could increase significantly. These increases in exposure can, however, be managed for the most part through targeted research and policy changes
Spectral method for the time-dependent Gross-Pitaevskii equation with a harmonic trap
We study the numerical resolution of the time-dependent Gross-Pitaevskii
equation, a non-linear Schroedinger equation used to simulate the dynamics of
Bose-Einstein condensates. Considering condensates trapped in harmonic
potentials, we present an efficient algorithm by making use of a spectral
Galerkin method, using a basis set of harmonic oscillator functions, and the
Gauss-Hermite quadrature. We apply this algorithm to the simulation of
condensate breathing and scissors modes.Comment: 23 pages, 5 figure
Differential cross section and recoil polarization measurements for the gamma p to K+ Lambda reaction using CLAS at Jefferson Lab
We present measurements of the differential cross section and Lambda recoil
polarization for the gamma p to K+ Lambda reaction made using the CLAS detector
at Jefferson Lab. These measurements cover the center-of-mass energy range from
1.62 to 2.84 GeV and a wide range of center-of-mass K+ production angles.
Independent analyses were performed using the K+ p pi- and K+ p (missing pi -)
final-state topologies; results from these analyses were found to exhibit good
agreement. These differential cross section measurements show excellent
agreement with previous CLAS and LEPS results and offer increased precision and
a 300 MeV increase in energy coverage. The recoil polarization data agree well
with previous results and offer a large increase in precision and a 500 MeV
extension in energy range. The increased center-of-mass energy range that these
data represent will allow for independent study of non-resonant K+ Lambda
photoproduction mechanisms at all production angles.Comment: 22 pages, 16 figure
Tensor Correlations Measured in 3He(e,e'pp)n
We have measured the 3He(e,e'pp)n reaction at an incident energy of 4.7 GeV
over a wide kinematic range. We identified spectator correlated pp and pn
nucleon pairs using kinematic cuts and measured their relative and total
momentum distributions. This is the first measurement of the ratio of pp to pn
pairs as a function of pair total momentum, . For pair relative
momenta between 0.3 and 0.5 GeV/c, the ratio is very small at low and
rises to approximately 0.5 at large . This shows the dominance of
tensor over central correlations at this relative momentum.Comment: 4 pages, 4 figures, submitted to PR
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