567 research outputs found

    Surface Integrity of SA508 Gr 3 Subjected to Abusive Milling Conditions

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    SA508 Gr 3, a bainitic forging steel employed in the fabrication of nuclear pressure vessels has been characterised after dry-milling to investigate extent of machining abuse on the surface. A detailed study of the evolution of residual stresses, microstructure, micro-hardness and roughness in relation to different milling parameters is presented. A central composite orthogonal (CCO) design of experiments (DoE) was used to generate a statistic model of the milling process. Deformation of the sub-surface layer was assessed via SEM BSE imaging. The developed statistical model is discussed aiming to illustrate availability of different cost-effective manufacturing techniques meeting the high standards required by the industry

    Expression and function of the bHLH genes ALCATRAZ and SPATULA in selected Solanaceae species

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    [EN] The genetic mechanisms underlying fruit development have been identified in Arabidopsis and have been comparatively studied in tomato as a representative of fleshy fruits. However, comparative expression and functional analyses on the bHLH genes downstream the genetic network, ALCATRAZ (ALC) and SPATULA (SPT), which are involved in the formation of the dehiscence zone in Arabidopsis, have not been functionally studied in the Solanaceae. Here, we perform detailed expression and functional studies of ALC/SPT homologs in Nicotiana obtusifolia with capsules, and in Capsicum annuum and Solanum lycopersicum with berries. In Solanaceae, ALC and SPT genes are expressed in leaves, and all floral organs, especially in petal margins, stamens and carpels; however, their expression changes during fruit maturation according to the fruit type. Functional analyses show that downregulation of ALC/SPT genes does not have an effect on gynoecium patterning; however, they have acquired opposite roles in petal expansion and have been co-opted in leaf pigmentation in Solanaceae. In addition, ALC/SPT genes repress lignification in time and space during fruit development in Solanaceae. Altogether, some roles of ALC and SPT genes are different between Brassicaceae and Solanaceae; while the paralogs have undergone some subfunctionalization in the former they are mostly redundant in the latter.This work was funded by COLCIENCIAS (111565842812), the iCOOP + 2016 COOPB20250 from the Centro Superior de Investigación Científica, CSIC, the ExpoSeed (H2020.MSCA-RISE-2015-691109) EU grant, the Convocatoria Programáticas 2017-16302, and the Estrategia de Sostenibilidad 2018-2019, from the Universidad de Antioquia. The authors would like to thank the group members of the Ferrándiz and Madueño Labs at IBMCP-UPV for training and help in the standardization of in situ hybridization. Finally, the authors thank Ricardo Callejas and Zulma Monsalve, from the Universidad de Antioquia, for their helpful suggestions during this research.Ortiz-Ramirez, CI.; Giraldo, MA.; Ferrandiz Maestre, C.; Pabon-Mora, N. (2019). Expression and function of the bHLH genes ALCATRAZ and SPATULA in selected Solanaceae species. The Plant Journal. 99(4):686-702. https://doi.org/10.1111/tpj.14352S686702994Golam Masu, A. S. M., Khandaker, L., Berthold, J., Gates, L., Peters, K., Delong, H., & Hossain, K. (2011). Anthocyanin, Total Polyphenols and Antioxidant Activity of Common Bean. American Journal of Food Technology, 6(5), 385-394. doi:10.3923/ajft.2011.385.394Atchley, W. R., Terhalle, W., & Dress, A. (1999). Positional Dependence, Cliques, and Predictive Motifs in the bHLH Protein Domain. 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    A Multi Agent Model for the Limit Order Book Dynamics

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    In the present work we introduce a novel multi-agent model with the aim to reproduce the dynamics of a double auction market at microscopic time scale through a faithful simulation of the matching mechanics in the limit order book. The agents follow a noise decision making process where their actions are related to a stochastic variable, "the market sentiment", which we define as a mixture of public and private information. The model, despite making just few basic assumptions over the trading strategies of the agents, is able to reproduce several empirical features of the high-frequency dynamics of the market microstructure not only related to the price movements but also to the deposition of the orders in the book.Comment: 20 pages, 11 figures, in press European Physical Journal B (EPJB

    Effect of Systemic Matrix Metalloproteinase Inhibition on Periodontal Wound Repair: A Proof of Concept Trial

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141196/1/jper0441.pd

    Emission spectra and intrinsic optical bistability in a two-level medium

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    Scattering of resonant radiation in a dense two-level medium is studied theoretically with account for local field effects and renormalization of the resonance frequency. Intrinsic optical bistability is viewed as switching between different spectral patterns of fluorescent light controlled by the incident field strength. Response spectra are calculated analytically for the entire hysteresis loop of atomic excitation. The equations to describe the non-linear interaction of an atomic ensemble with light are derived from the Bogolubov-Born-Green-Kirkwood-Yvon hierarchy for reduced single particle density matrices of atoms and quantized field modes and their correlation operators. The spectral power of scattered light with separated coherent and incoherent constituents is obtained straightforwardly within the hierarchy. The formula obtained for emission spectra can be used to distinguish between possible mechanisms suggested to produce intrinsic bistability.Comment: 18 pages, 5 figure

    A probabilistic model for gene content evolution with duplication, loss, and horizontal transfer

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    We introduce a Markov model for the evolution of a gene family along a phylogeny. The model includes parameters for the rates of horizontal gene transfer, gene duplication, and gene loss, in addition to branch lengths in the phylogeny. The likelihood for the changes in the size of a gene family across different organisms can be calculated in O(N+hM^2) time and O(N+M^2) space, where N is the number of organisms, hh is the height of the phylogeny, and M is the sum of family sizes. We apply the model to the evolution of gene content in Preoteobacteria using the gene families in the COG (Clusters of Orthologous Groups) database

    Measurements of the observed cross sections for e+ee^+e^-\to exclusive light hadrons containing π0π0\pi^0\pi^0 at s=3.773\sqrt s= 3.773, 3.650 and 3.6648 GeV

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    By analyzing the data sets of 17.3, 6.5 and 1.0 pb1^{-1} taken, respectively, at s=3.773\sqrt s= 3.773, 3.650 and 3.6648 GeV with the BES-II detector at the BEPC collider, we measure the observed cross sections for e+eπ+ππ0π0e^+e^-\to \pi^+\pi^-\pi^0\pi^0, K+Kπ0π0K^+K^-\pi^0\pi^0, 2(π+ππ0)2(\pi^+\pi^-\pi^0), K+Kπ+ππ0π0K^+K^-\pi^+\pi^-\pi^0\pi^0 and 3(π+π)π0π03(\pi^+\pi^-)\pi^0\pi^0 at the three energy points. Based on these cross sections we set the upper limits on the observed cross sections and the branching fractions for ψ(3770)\psi(3770) decay into these final states at 90% C.L..Comment: 7 pages, 2 figure

    Partial wave analysis of J/\psi \to \gamma \phi \phi

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    Using 5.8×107J/ψ5.8 \times 10^7 J/\psi events collected in the BESII detector, the radiative decay J/ψγϕϕγK+KKS0KL0J/\psi \to \gamma \phi \phi \to \gamma K^+ K^- K^0_S K^0_L is studied. The ϕϕ\phi\phi invariant mass distribution exhibits a near-threshold enhancement that peaks around 2.24 GeV/c2c^{2}. A partial wave analysis shows that the structure is dominated by a 0+0^{-+} state (η(2225)\eta(2225)) with a mass of 2.240.02+0.030.02+0.032.24^{+0.03}_{-0.02}{}^{+0.03}_{-0.02} GeV/c2c^{2} and a width of 0.19±0.030.04+0.060.19 \pm 0.03^{+0.06}_{-0.04} GeV/c2c^{2}. The product branching fraction is: Br(J/ψγη(2225))Br(η(2225)ϕϕ)=(4.4±0.4±0.8)×104Br(J/\psi \to \gamma \eta(2225))\cdot Br(\eta(2225)\to \phi\phi) = (4.4 \pm 0.4 \pm 0.8)\times 10^{-4}.Comment: 11 pages, 4 figures. corrected proof for journa

    Direct Measurements of Absolute Branching Fractions for D0 and D+ Inclusive Semimuonic Decays

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    By analyzing about 33 pb1\rm pb^{-1} data sample collected at and around 3.773 GeV with the BES-II detector at the BEPC collider, we directly measure the branching fractions for the neutral and charged DD inclusive semimuonic decays to be BF(D0μ+X)=(6.8±1.5±0.7)BF(D^0 \to \mu^+ X) =(6.8\pm 1.5\pm 0.7)% and BF(D+μ+X)=(17.6±2.7±1.8)BF(D^+ \to \mu^+ X) =(17.6 \pm 2.7 \pm 1.8)%, and determine the ratio of the two branching fractions to be BF(D+μ+X)BF(D0μ+X)=2.59±0.70±0.25\frac{BF(D^+ \to \mu^+ X)}{BF(D^0 \to \mu^+ X)}=2.59\pm 0.70 \pm 0.25

    Measurements of the observed cross sections for exclusive light hadron production in e^+e^- annihilation at \sqrt{s}= 3.773 and 3.650 GeV

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    By analyzing the data sets of 17.3 pb1^{-1} taken at s=3.773\sqrt{s}=3.773 GeV and 6.5 pb1^{-1} taken at s=3.650\sqrt{s}=3.650 GeV with the BESII detector at the BEPC collider, we have measured the observed cross sections for 12 exclusive light hadron final states produced in e+ee^+e^- annihilation at the two energy points. We have also set the upper limits on the observed cross sections and the branching fractions for ψ(3770)\psi(3770) decay to these final states at 90% C.L.Comment: 8 pages, 5 figur
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