Modeling infectious disease dynamics in the complex landscape of global health.

Despite some notable successes in the control of infectious diseases, transmissible pathogens still pose an enormous threat to human and animal health. The ecological and evolutionary dynamics of infections play out on a wide range of interconnected temporal, organizational, and spatial scales, which span hours to months, cells to ecosystems, and local to global spread. Moreover, some pathogens are directly transmitted between individuals of a single species, whereas others circulate among multiple hosts, need arthropod vectors, or can survive in environmental reservoirs. Many factors, including increasing antimicrobial resistance, increased human connectivity and changeable human behavior, elevate prevention and control from matters of national policy to international challenge. In the face of this complexity, mathematical models offer valuable tools for synthesizing information to understand epidemiological patterns, and for developing quantitative evidence for decision-making in global health

Dynamic protein methylation in chromatin biology

Post-translational modification of chromatin is emerging as an increasingly important regulator of chromosomal processes. In particular, histone lysine and arginine methylation play important roles in regulating transcription, maintaining genomic integrity, and contributing to epigenetic memory. Recently, the use of new approaches to analyse histone methylation, the generation of genetic model systems, and the ability to interrogate genome wide histone modification profiles has aided in defining how histone methylation contributes to these processes. Here we focus on the recent advances in our understanding of the histone methylation system and examine how dynamic histone methylation contributes to normal cellular function in mammals

Erratum: [Díaz, A.I., Pagel, B.E.J., Edmunds, M.G., Phillips, M.M. On the nature of the stellar population in the nucleus of the Sd galaxy NGC 7793. Monthly Notices of the Royal Astronomical Society 201 (1982) : 49-55]

This is an electronic version of an article published in Monthly Notices of the Royal Astronomical Society. Díaz, A.I., Pagel, B.E.J., Edmunds, M.G. and M.M. Phillips. Erratum - On the nature of the stellar population in the nucleus of the Sd galaxy NGC 7793. Monthly Notices of the Royal Astronomical Society 202 (1983): 83

Nuclear activity in two spiral galaxies with jets: NGC 1097 and 1598

This is an electronic version of an article published in Monthly Notices of the Royal Astronomical Society. Phillips, M.M., Pagel, B.E.J., Edmunds, M.G., Díaz, A. Nuclear activity in two spiral galaxies with jets: NGC 1097 and 1598. Monthly Notices of the Royal Astronomical Society 210 (1984): 701-7

The chemical composition gradient across M 33

This is an electronic version of an article published in Monthly Notices of the Royal Astronomical Society. Vilchez, J.M., Pagel, B.E.J., Díaz, A.I., Terlevich, E. and M.G. Edmunds. The chemical composition gradient across M 33. Monthly Notices of the Royal Astronomical Society 235 (1988): 633-65

Abundance analysis of giant H II regions in nearby spirals

This is an electronic version of an article published in Revista Mexicana de Astronomía y Astrofísica. Díaz, Angeles I. et al. Abundance analysis of giant H II regions in nearby spirals. Revista Mexicana de Astronomía y Astrofísica 21 (1990): 223-22