Tracing the String: BMN correspondence at Finite J^2/N

Employing the string bit formalism of hep-th/0209215, we identify the basis transformation that relates BMN operators in N=4 gauge theory to string states in the dual string field theory at finite g_2=J^2/N. In this basis, the supercharge truncates at linear order in g_2, and the mixing amplitude between 1 and 2-string states precisely matches with the (corrected) answer of hep-th/0206073 for the 3-string amplitude in light-cone string field theory. Supersymmetry then predicts the order g_2^2 contact term in the string bit Hamiltonian. The resulting leading order mass renormalization of string states agrees with the recently computed shift in conformal dimension of BMN operators in the gauge theory.Comment: 11 pages, 1 figur

Butyrate Prevents Induction of CXCL10 and Non-Canonical IRF9 Expression by Activated Human Intestinal Epithelial Cells via HDAC Inhibition

Non-communicable diseases are increasing and have an underlying low-grade inflammation in common, which may affect gut health. To maintain intestinal homeostasis, unwanted epithelial activation needs to be avoided. This study compared the efficacy of butyrate, propionate and acetate to suppress IFN-γ+/−TNF-α induced intestinal epithelial activation in association with their HDAC inhibitory capacity, while studying the canonical and non-canonical STAT1 pathway. HT-29 were activated with IFN-γ+/−TNF-α and treated with short chain fatty acids (SCFAs) or histone deacetylase (HDAC) inhibitors. CXCL10 release and protein and mRNA expression of proteins involved in the STAT1 pathway were determined. All SCFAs dose-dependently inhibited CXCL10 release of the cells after activation with IFN-γ or IFN-γ+TNF-α. Butyrate was the most effective, completely preventing CXCL10 induction. Butyrate did not affect phosphorylated STAT1, nor phosphorylated NFκB p65, but inhibited IRF9 and phosphorylated JAK2 protein expression in activated cells. Additionally, butyrate inhibited CXCL10, SOCS1, JAK2 and IRF9 mRNA in activated cells. The effect of butyrate was mimicked by class I HDAC inhibitors and a general HDAC inhibitor Trichostatin A. Butyrate is the most potent inhibitor of CXCL10 release compared to other SCFAs and acts via HDAC inhibition. This causes downregulation of CXCL10, JAK2 and IRF9 genes, resulting in a decreased IRF9 protein expression which inhibits the non-canonical pathway and CXCL10 transcription

Fluorescent carbon dioxide indicators

Over the last decade, fluorescence has become the dominant tool in biotechnology and medical imaging. These exciting advances have been underpinned by the advances in time-resolved techniques and instrumentation, probe design, chemical / biochemical sensing, coupled with our furthered knowledge in biology. Complementary volumes 9 and 10, Advanced Concepts of Fluorescence Sensing: Small Molecule Sensing and Advanced Concepts of Fluorescence Sensing: Macromolecular Sensing, aim to summarize the current state of the art in fluorescent sensing. For this reason, Drs. Geddes and Lakowicz have invited chapters, encompassing a broad range of fluorescence sensing techniques. Some chapters deal with small molecule sensors, such as for anions, cations, and CO2, while others summarize recent advances in protein-based and macromolecular sensors. The Editors have, however, not included DNA or RNA based sensing in this volume, as this were reviewed in Volume 7 and is to be the subject of a more detailed volume in the near future

Abuse-related post-traumatic stress during the childbearing year

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75405/1/j.1365-2648.2004.03051.x.pd

Soluble CD52 is an indicator of disease activity in chronic lymphocytic leukemia

Biological, physical and clinical aspects of cancer treatment with ionising radiatio

Temporal progress and spatial patterns of quiescent diseases in guava influenced by sanitation practices

ABSTRACT: Postharvest diseases are a major problem in guava crops as the symptoms normally appear during fruit ripening. This study aimed to detect and characterize the temporal dynamics and spatial patterns of the most important guava diseases in orchards with and without removal of crop residues as a sanitation practice. The experiment was conducted in an orchard of ‘Pedro Sato’ guavas, over two consecutive seasons, and data were collected from the flowering to the fruit ripening stage. In immature guavas treated with paraquat and ethrel, Colletotrichum spp. was detected from the 5th day of incubation. Anthracnose was detected in flowers at incidences higher than 50 % and black spot in fruit larger than 5.5 cm in length. The monomolecular and the exponential models provided the best fit to anthracnose and black spot incidence progress curve data, respectively. Both diseases showed a predominantly random spatial pattern in the orchard. The removal of crop residues reduced the rate of disease progress in at least one season, and was effective in reducing the areas under the quiescent disease progress curves (AUDPC) of anthracnose. Anthracnose incidence increased from 57 to 96 % and black spot from 1 to 48 %, respectively, at fruit maturation levels 1 and 3. A negative correlation was found between disease incidence and the color of the fruit skin (°h). Fruit harvested during the later maturation stages showed higher incidence of the diseases. Due to the wide distribution and early infection of quiescent diseases, starting at flowering, preventive management should consider disease monitoring and removal of crop residues

(Anti-)deuteron production in pp collisions at 1as=13TeV

The study of (anti-)deuteron production in pp collisions has proven to be a powerful tool to investigate the formation mechanism of loosely bound states in high-energy hadronic collisions. In this paper the production of (anti-)deuterons is studied as a function of the charged particle multiplicity in inelastic pp collisions at s=13 TeV using the ALICE experiment. Thanks to the large number of accumulated minimum bias events, it has been possible to measure (anti-)deuteron production in pp collisions up to the same charged particle multiplicity (d Nch/ d \u3b7 3c 26) as measured in p\u2013Pb collisions at similar centre-of-mass energies. Within the uncertainties, the deuteron yield in pp collisions resembles the one in p\u2013Pb interactions, suggesting a common formation mechanism behind the production of light nuclei in hadronic interactions. In this context the measurements are compared with the expectations of coalescence and statistical hadronisation models (SHM)