1,353 research outputs found
Probing quantum and classical turbulence analogy through global bifurcations in a von K\'arm\'an liquid Helium experiment
We report measurements of the dissipation in the Superfluid Helium high
REynold number von Karman flow (SHREK) experiment for different forcing
conditions, through a regime of global hysteretic bifurcation. Our
macroscopical measurements indicate no noticeable difference between the
classical fluid and the superfluid regimes, thereby providing evidence of the
same dissipative anomaly and response to asymmetry in fluid and superfluid
regime. %In the latter case, A detailed study of the variations of the
hysteretic cycle with Reynolds number supports the idea that (i) the stability
of the bifurcated states of classical turbulence in this closed flow is partly
governed by the dissipative scales and (ii) the normal and the superfluid
component at these temperatures (1.6K) are locked down to the dissipative
length scale.Comment: 5 pages, 5 figure
Probability Density Function of Longitudinal Velocity Increment in Homogeneous Turbulence
Two conditional averages for the longitudinal velocity increment u_r of the
simulated turbulence are calculated: h(u_r) is the average of the increment of
the longitudinal Laplacian velocity field with u_r fixed, while g(u_r) is the
corresponding one of the square of the difference of the gradient of the
velocity field. Based on the physical argument, we suggest the formulae for h
and g, which are quite satisfactorily fitted to the 512^3 DNS data. The
predicted PDF is characterized as
(1) the Gaussian distribution for the small amplitudes,
(2) the exponential distribution for the large ones, and (3) a prefactor
before the exponential function for the intermediate ones.Comment: 4 pages, 4 figures, using RevTeX3.
Setting the stage: social-environmental and motivational predictors of optimal training engagement
In this paper, we will firstly explore the central tenets of SDT. Research that has examined the social-environmental and motivation-related correlates of optimal training, performance and health-related engagement through the theoretical lens of SDT will be reviewed. Drawing from SDT-driven work undertaken in educational, sport and dance settings, we will draw conclusions and suggest future directions from a research and applied perspective
Simulations of Spinodal Nucleation in Systems with Elastic Interactions
Systems with long-range interactions quenched into a metastable state near
the pseudospinodal exhibit nucleation that is qualitatively different than the
classical nucleation observed near the coexistence curve. We have observed
nucleation droplets in our Langevin simulations of a two-dimensional model of
martensitic transformations and have determined that the structure of the
nucleating droplet differs from the stable martensite structure. Our results,
together with experimental measurements of the phonon dispersion curve, allow
us to predict the nature of the droplet. These results have implications for
nucleation in many solid-solid transitions and the structure of the final
state
First HARPSpol discoveries of magnetic fields in massive stars
In the framework of the Magnetism in Massive Stars (MiMeS) project, a
HARPSpol Large Program at the 3.6m-ESO telescope has recently started to
collect high-resolution spectropolarimetric data of a large number of Southern
massive OB stars in the field of the Galaxy and in many young clusters and
associations. In this Letter, we report on the first discoveries of magnetic
fields in two massive stars with HARPSpol - HD 130807 and HD 122451, and
confirm the presence of a magnetic field at the surface of HD 105382 that was
previously observed with a low spectral resolution device. The longitudinal
magnetic field measurements are strongly varying for HD 130807 from -100
G to 700 G. Those of HD 122451 and HD 105382 are less variable with
values ranging from -40 to -80 G, and from -300 to -600 G,
respectively. The discovery and confirmation of three new magnetic massive
stars, including at least two He-weak stars, is an important contribution to
one of the MiMeS objectives: the understanding of origin of magnetic fields in
massive stars and their impacts on stellar structure and evolution.Comment: 4 pages, 2 figures, accepted for publication in A&A Lette
The Active Corona of HD 35850 (F8 V)
We present Extreme Ultraviolet Explorer spectroscopy and photometry of the
nearby F8 V star HD 35850 (HR 1817). The EUVE spectra reveal 28 emission lines
from Fe IX and Fe XV to Fe XXIV. The Fe XXI 102, 129 A ratio yields an upper
limit for the coronal electron density, log n < 11.6 per cc. The EUVE SW
spectrum shows a small but clearly detectable continuum. The line-to-continuum
ratio indicates approximately solar Fe abundances, 0.8 < Z < 1.6. The resulting
emission-measure distribution is characterized by two temperature components at
log T of 6.8 and 7.4. The EUVE spectra have been compared with non-simultaneous
ASCA SIS spectra of HD 35850. The SIS spectrum shows the same temperature
distribution as the EUVE DEM analysis. However, the SIS spectral firs suggest
sub-solar abundances, 0.34 < Z < 0.81. Although some of the discrepancy may be
the result of incomplete X-ray line lists, we cannot explain the disagreement
between the EUVE line-to-continuum ratio and the ASCA-derived Fe abundance.
Given its youth (t ~ 100 Myr), its rapid rotation (v sin i ~ 50 km/s), and its
high X-ray activity (Lx ~ 1.5E+30 ergs/s), HD 35850 may represent an activity
extremum for single, main-sequence F-type stars. The variability and EM
distribution can be reconstructed using the continuous flaring model of Guedel
provided that the flare distribution has a power-law index of 1.8. Similar
results obtained for other young solar analogs suggest that continuous flaring
is a viable coronal heating mechanism on rapidly rotating, late-type,
main-sequence stars.Comment: 32 pages incl. 14 figures and 3 tables. To appear in the 1999 April
10 issue of The Astrophysical Journa
Severe hypoglycemia in users of sulfonylurea antidiabetic agents and antihyperlipidemics
Drug-drug interactions causing severe hypoglycemia due to antidiabetic drugs is a major clinical and public health problem. We assessed whether sulfonylurea use with a statin or fibrate was associated with severe hypoglycemia. We conducted cohort studies of users of glyburide, glipizide, and glimepiride plus a statin or fibrate within a Medicaid population. The outcome was a validated, diagnosis-based algorithm for severe hypoglycemia. Among 592,872 persons newly exposed to a sulfonylurea+antihyperlipidemic, the incidence of severe hypoglycemia was 5.8/100 person-years. Adjusted hazard ratios (HRs) for sulfonylurea+statins were consistent with no association. Most overall HRs for sulfonylurea+fibrate were elevated, with sulfonylurea-specific adjusted HRs as large as 1.50 (95% confidence interval (CI): 1.24-1.81) for glyburide+gemfibrozil, 1.37 (95% CI: 1.11-1.69) for glipizide+gemfibrozil, and 1.63 (95% CI: 1.29-2.06) for glimepiride+fenofibrate. Concomitant therapy with a sulfonylurea and fibrate is associated with an often delayed increased rate of severe hypoglycemia
Comparative risk of severe hypoglycemia among concomitant users of thiazolidinedione antidiabetic agents and antihyperlipidemics
We conducted high-dimensional propensity score-adjusted cohort studies to examine whether thiazolidinedione use with a statin or fibrate was associated with an increased risk of severe hypoglycemia. We found that concomitant therapy with a thiazolidinedione+fibrate was associated with a generally delayed increased risk of severe hypoglycemia
In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta
BACKGROUND:
Fetal programming describes the theory linking environmental conditions during embryonic and fetal development with risk of diseases later in life. Environmental insults in utero may lead to changes in epigenetic mechanisms potentially affecting fetal development. OBJECTIVES:
We examined associations between in utero exposures, infant growth, and methylation of repetitive elements and gene-associated DNA in human term placenta tissue samples. METHODS:
Placental tissues and associated demographic and clinical data were obtained from subjects delivering at Women and Infants Hospital in Providence, Rhode Island (USA). Methylation levels of long interspersed nuclear element-1 (LINE-1) and the Alu element AluYb8 were determined in 380 placental samples from term deliveries using bisulfite pyrosequencing. Genomewide DNA methylation profiles were obtained in a subset of 184 samples using the Illumina Infinium HumanMethylation27 BeadArray. Multiple linear regression, model-based clustering methods, and gene set enrichment analysis examined the association between birth weight percentile, demographic variables, and repetitive element methylation and gene-associated CpG locus methylation. RESULTS:
LINE-1 and AluYb8 methylation levels were found to be significantly positively associated with birth weight percentile (p = 0.01 and p \u3c 0.0001, respectively) and were found to differ significantly among infants exposed to tobacco smoke and alcohol. Increased placental AluYb8 methylation was positively associated with average methylation among CpG loci found in polycomb group target genes; developmentally related transcription factor binding sites were overrepresented for differentially methylated loci associated with both elements. CONCLUSIONS:
Our results suggest that repetitive element methylation markers, most notably AluYb8 methylation, may be susceptible to epigenetic alterations resulting from the intrauterine environment and play a critical role in mediating placenta function, and may ultimately inform on the developmental basis of health and disease
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