Toxicity studies of combination of silver nanoparticles and cryogels

The combination "cryogel + nanoparticles" allows developing a new type of wound dressing, where antimicrobial properties of silver nanoparticles made have been utilized. Previous reports have shown that the production of shaped nanoparticles and the incorporation onto cryogels is feasible [1-2]. This study investigates the toxicity of these constructs to primary human dermal fibroblast cells in context of possible clinical application

Toxicity studies of combination of silver nanoparticles and cryogels

The combination "cryogel + nanoparticles" allows developing a new type of wound dressing, where antimicrobial properties of silver nanoparticles made have been utilized. Previous reports have shown that the production of shaped nanoparticles and the incorporation onto cryogels is feasible [1-2]. This study investigates the toxicity of these constructs to primary human dermal fibroblast cells in context of possible clinical application

One-step synthesis of γ-Fe₂ O₃/Fe₃ O₄ nanocomposite for sensitive electrochemical detection of hydrogen peroxide

Maghemite/magnetite nanocomposite ( γ-Fe₂ O₃/Fe₃ O₄ ) was prepared via an electrochemical method using pulse alternating current and applied for electrocatalytic reduction and sensing of hydrogen peroxide. The structural and compositional analysis of the γ-Fe₂ O₃/Fe₃ O₄ was characterized by XRD, SEM, TEM and XPS. Its thermal decomposition behavior was studied using TG/DSC. The mechanism for γ- Fe₂ O₃/Fe₃ O₄ nanocomposite formation was propose

Lower pole obstructive megaureter of duplex kidney: an exception to the Weigert-Meyer rule

Introduction. Anatomical features of the urinary tract in patients with duplicate kidneys are described using the Weigert-Meyer rule, since the orifice of the upper ureter has an ectopic location (inferomedial) and the orifice of the lower ureter has an orthotopic location (superolateral). However, there are rare cases of violation of this rule, complicated by obstructive megaureter, ectopic ureteral orifice, the presence of ureterocele.Objective. To report the rare clinical case of a lower pole obstructive megaureter as a violation of the Meyer-Weigert rule in the patient with complete ureteral duplication and to describe the use of ureteroureterostomy as an effective and safe method of surgical correction of the presented anomaly.Clinical case. We present a case of the infant (5 months old) with a lower pole obstructive megaureter. This pathology was identified through intravenous urography and voiding cystourethrography. Laparoscopic proximal end-to-side ureteroureteroanastomosis was chosen as a surgical treatment. Postoperative control intravenous urography showed the effectiveness (a reduction in the lower pole collecting system of the duplex kidney was revealed) and the safety of this method of correction.Conclusion.  There are only several clinical cases about exceptions to the Weigert-Meyer rule reported in literature, and most of them are about adult patients. The main surgical method of treatment in such cases is heminephrectomy. To our knowledge, this is the only reported case of using ureteroureterostomy in the patient with a lower pole obstructive megaureter. This technique has shown its effectiveness and safety for restoring the patency of the urinary tract, confirmed during the control postoperative examination