2D-3D registration of CT vertebra volume to fluoroscopy projection: A calibration model assessment (doi:10.1155/2010/806094)

This study extends a previous research concerning intervertebral motion registration by means of 2D dynamic fluoroscopy to obtain a more comprehensive 3D description of vertebral kinematics. The problem of estimating the 3D rigid pose of a CT volume of a vertebra from its 2D X-ray fluoroscopy projection is addressed. 2D-3D registration is obtained maximising a measure of similarity between Digitally Reconstructed Radiographs (obtained from the CT volume) and real fluoroscopic projection. X-ray energy correction was performed. To assess the method a calibration model was realised a sheep dry vertebra was rigidly fixed to a frame of reference including metallic markers. Accurate measurement of 3D orientation was obtained via single-camera calibration of the markers and held as true 3D vertebra position; then, vertebra 3D pose was estimated and results compared. Error analysis revealed accuracy of the order of 0.1 degree for the rotation angles of about 1?mm for displacements parallel to the fluoroscopic plane, and of order of 10?mm for the orthogonal displacement.<br/

Improving Visual Field Examination of the Macula Using Structural Information

Purpose: To investigate a novel approach for structure-function modeling in glaucoma to improve visual field testing in the macula. Methods: We acquired data from the macular region in 20 healthy eyes and 31 with central glaucomatous damage. Optical coherence tomography (OCT) scans were used to estimate the local macular ganglion cell density. Perimetry was performed with a fundus-tracking device using a 10-2 grid. OCT scans were matched to the retinal image from the fundus perimeter to accurately map the tested locations onto the structural damage. Binary responses from the subjects to all presented stimuli were used to calculate the structure-function model used to generate prior distributions for a ZEST (Zippy Estimation by Sequential Testing) Bayesian strategy. We used simulations based on structural and functional data acquired from an independent dataset of 20 glaucoma patients to compare the performance of this new strategy, structural macular ZEST (MacS-ZEST), with a standard ZEST. Results: Compared to the standard ZEST, MacS-ZEST reduced the number of presentations by 13% in reliable simulated subjects and 14% with higher rates (≥20%) of false positive or false negative errors. Reduction in mean absolute error was not present for reliable subjects but was gradually more important with unreliable responses (≥10% at 30% error rate). Conclusions: Binary responses can be modeled to incorporate detailed structural information from macular OCT into visual field testing, improving overall speed and accuracy in poor responders. Translational Relevance: Structural information can improve speed and reliability for macular testing in glaucoma practice

Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation

FUNDING Biotechnology and Biological Sciences Research Council (BBSRC) [BB/I020926/1 to I.S.]; BBSRC PhD studentship award [C103817D to I.S. and M.C.R.]; Scottish Universities Life Science Alliance PhD studentship award (to M.C.R. and I.S.]. Funding for open access charge: BBSRC. Conflict of interest statement. None declared.Peer reviewedPublisher PD

Satellite observations of reconnection between emerging and pre-existing small-scale magnetic fields

We report multi-wavelength ultraviolet observations taken with the IRIS satellite, concerning the emergence phase in the upper chromosphere and transition region of an emerging flux region (EFR) embedded in the unipolar plage of active region NOAA 12529. The photospheric configuration of the EFR is analyzed in detail benefitting from measurements taken with the spectropolarimeter aboard the Hinode satellite, when the EFR was fully developed. In addition, these data are complemented by full-disk, simultaneous observations of the SDO satellite, relevant to the photosphere and the corona. In the photosphere, magnetic flux emergence signatures are recognized in the fuzzy granulation, with dark alignments between the emerging polarities, cospatial with highly inclined fields. In the upper atmospheric layers, we identify recurrent brightenings that resemble UV bursts, with counterparts in all coronal passbands. These occur at the edges of the EFR and in the region of the arch filament system (AFS) cospatial to the EFR. Jet activity is also found at chromospheric and coronal levels, near the AFS and the observed brightness enhancement sites. The analysis of the IRIS line profiles reveals the heating of dense plasma in the low solar atmosphere and the driving of bi-directional high-velocity flows with speeds up to 100 km/s at the same locations. Furthermore, we detect a correlation between the Doppler velocity and line width of the Si IV 1394 and 1402 \AA{} line profiles in the UV burst pixels and their skewness. Comparing these findings with previous observations and numerical models, we suggest evidence of several long-lasting, small-scale magnetic reconnection episodes between the emerging bipole and the ambient field. This process leads to the cancellation of a pre-existing photospheric flux concentration of the plage with the opposite polarity flux patch of the EFR. [...]Comment: 4 pages, 2 figures, to be published in "Nuovo Cimento C" as proceeding of the Third Meeting of the Italian Solar and Heliospheric Communit

Chemical abundances in the nucleus of the Sagittarius dwarf spheroidal galaxy

We present Iron, Magnesium, Calcium, and Titanium abundances for 235 stars in the central region of the Sagittarius dwarf spheroidal galaxy (within 9.0 arcmin ~70 pc from the center) from medium-resolution Keck/DEIMOS spectra. All the considered stars belong to the massive globular cluster M54 or to the central nucleus of the galaxy (Sgr,N). In particular we provide abundances for 109 stars with [Fe/H] > -1.0, more than doubling the available sample of spectroscopic metallicity and alpha-elements abundance estimates for Sgr dSph stars in this metallicity regime. Also, we find the first confirmed member of the Sagittarius dwarf spheroidal with [Fe/H]< -2.0 based on analysis of iron lines. We find for the first time a metallicity gradient in the Sgr,N population, whose peak iron abundance goes from [Fe/H]=-0.38 for R < 2.5 arcmin to [Fe/H]=-0.57 for 5.0 < R < 9.0 arcmin. On the other hand the trends of [Mg/Fe], [Ca/Fe], and [Ti/Fe] with [Fe/H] are the same over the entire region explored by our study. We reproduce the observed chemical patterns of the Sagittarius dwarf spheroidal as a whole with a chemical evolution model implying a high mass progenitor ( M_(DM)=6 X 10^{10} Msun ) and a significant event of mass-stripping occurred a few Gyr ago, presumably starting at the first peri-Galactic passage after infall.Comment: Accepted for publication to A&A, 12 pages, 14 figures, 1 tabl

Spin-orbital coupling in a triplet superconductor-ferromagnet junction

We study a novel type of coupling between spin and orbital degrees of freedom which appears at triplet superconductor-ferromagnet interfaces. Using a self-consistent spatially-dependent mean-field theory, we show that increasing the angle between the ferromagnetic moment and the triplet vector order parameter enhances or suppresses the p-wave gap close to the interface, according as the gap antinodes are parallel or perpendicular to the boundary, respectively. The associated change in condensation energy establishes an orbitally-dependent preferred orientation for the magnetization. When both gap components are present, as in a chiral superconductor, we observe a first-order transition between different moment orientations as a function of the exchange field strength.Comment: 5 pages, 4 figures and Supplemental Material (3 pages

Orchestrating Forest Policy in Italy: Mission Impossible?

In the Italian political and economic agenda the forest sector occupies a marginal role. The forest sector in Italy is characterized by a high institutional fragmentation and centralized decision-making processes dominated by Public Forest Administrations. Public participation in forest policy processes has been implemented since the 1990s at national, regional and local levels in several cases. However, today no significant changes have been observed in the overall governance of the forest sector and stakeholders' involvement in Italian forest policy decision-making is still rather limited. The aims of this paper are to describe the state of forest-related participatory processes in Italy at various levels (national, regional and local) and identify which factors and actors hinder or support the establishment and implementation of participatory forest-related processes in the country. The forest-related participatory processes are analyzed adopting a qualitative-based approach and interpreting interactive, complex and non-linear participatory processes through the lens of panarchy theory

Development and experimentation of LQR/APF guidance and control for autonomous proximity maneuvers of multiple spacecraft

http://dx.doi.org/10.1016/j.actaastro.2010.08.012This work introduces a novel control algorithm for close proximity multiple spacecraft autonomous maneuvers, based on hybrid linear quadratic regulator/artificial potential function (LQR/APF), for applications including autonomous docking, on-orbit assembly and spacecraft servicing. Both theoretical developments and experimental validation of the proposed approach are presented. Fuel consumption is sub-optimized in real-time through re-computation of the LQR at each sample time, while performing collision avoidance through the APF and a high level decisional logic. The underlying LQR/APF controller is integrated with a customized wall-following technique and a decision logic, overcoming problems such as local minima. The algorithm is experimentally tested on a four spacecraft simulators test bed at the Spacecraft Robotics Laboratory of the NAval Postgraduate School. The metrics to evaluate the control algorithm are: autonomy of the system in making decisions, successful completion of the maneuver, required time, and propellant consumption