4,107 research outputs found

    Wikimedia and universities: contributing to the global commons in the Age of Disinformation

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    In its first 30 years the world wide web has revolutionized the information environment. However, its impact has been negative as well as positive, through corporate misuse of personal data and due to its potential for enabling the spread of disinformation. As a large-scale collaborative platform funded through charitable donations, with a mission to provide universal free access to knowledge as a public good, Wikipedia is one of the most popular websites in the world. This paper explores the role of Wikipedia in the information ecosystem where it occupies a unique role as a bridge between informal discussion and scholarly publication. We explore how it relates to the broader Wikimedia ecosystem, through structured data on Wikidata for instance, and openly licensed media on Wikimedia Commons. We consider the potential benefits for universities in the areas of information literacy and research impact, and investigate the extent to which universities in the UK and their libraries are engaging strategically with Wikimedia, if at all

    Are infestations of Cymomelanodactylus killing Acropora cytherea in the Chagos archipelago?

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    Associations between branching corals and infaunal crabs are well known, mostly due to the beneficial effects of Trapezia and Tetralia crabs in protecting host corals from crown-of-thorns starfish (e.g., Pratchett et al. 2000) and/or sedimentation (Stewart et al. 2006). These crabs are obligate associates of live corals and highly prevalent across suitable coral hosts, with 1–2 individuals per colony (Patton 1994). Cymo melanodactylus (Fig. 1) are also prevalent in branching corals, mostly Acropora, and are known to feed on live coral tissue, but are generally found in low abundance (<3 per colony) and do not significantly affect their host corals (e.g., Patton 1994). In the Chagos archipelago, however, infestations of Cymo melanodactylus were found on recently dead and dying colonies of Acropora cytherea

    Perfect Reflection of Light by an Oscillating Dipole

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    We show theoretically that a directional dipole wave can be perfectly reflected by a single point-like oscillating dipole. Furthermore, we find that in the case of a strongly focused plane wave up to 85 % of the incident light can be reflected by the dipole. Our results hold for the full spectrum of the electromagnetic interactions and have immediate implications for achieving strong coupling between a single propagating photon and a single quantum emitter.Comment: 3 figure

    The Anti-Coincidence Detector for the GLAST Large Area Telescope

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    This paper describes the design, fabrication and testing of the Anti-Coincidence Detector (ACD) for the Gamma-ray Large Area Space Telescope (GLAST) Large Area Telescope (LAT). The ACD is LAT first-level defense against the charged cosmic ray background that outnumbers the gamma rays by 3-5 orders of magnitude. The ACD covers the top and 4 sides of the LAT tracking detector, requiring a total active area of ~8.3 square meters. The ACD detector utilizes plastic scintillator tiles with wave-length shifting fiber readout. In order to suppress self-veto by shower particles at high gamma-ray energies, the ACD is segmented into 89 tiles of different sizes. The overall ACD efficiency for detection of singly charged relativistic particles entering the tracking detector from the top or sides of the LAT exceeds the required 0.9997.Comment: 33 pages, 19 figure

    Phase sensitive detection of dipole radiation in a fiber-based high numerical aperture optical system

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    We theoretically study the problem of detecting dipole radiation in an optical system of high numerical aperture in which the detector is sensitive to \textit{field amplitude}. In particular, we model the phase sensitive detector as a single-mode cylindrical optical fiber. We find that the maximum in collection efficiency of the dipole radiation does not coincide with the optimum resolution for the light gathering instrument. The calculated results are important for analyzing fiber-based confocal microscope performance in fluorescence and spectroscopic studies of single molecules and/or quantum dots.Comment: 12 pages, 2 figure

    Plasmid classification in an era of whole-genome sequencing: application in studies of antibiotic resistance epidemiology

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    Plasmids are extra-chromosomal genetic elements ubiquitous in bacteria, and commonly transmissible between host cells. Their genomes include variable repertoires of ‘accessory genes,’ such as antibiotic resistance genes, as well as ‘backbone’ loci which are largely conserved within plasmid families, and often involved in key plasmid-specific functions (e.g., replication, stable inheritance, mobility). Classifying plasmids into different types according to their phylogenetic relatedness provides insight into the epidemiology of plasmid-mediated antibiotic resistance. Current typing schemes exploit backbone loci associated with replication (replicon typing), or plasmid mobility (MOB typing). Conventional PCR-based methods for plasmid typing remain widely used. With the emergence of whole-genome sequencing (WGS), large datasets can be analyzed using in silico plasmid typing methods. However, short reads from popular high-throughput sequencers can be challenging to assemble, so complete plasmid sequences may not be accurately reconstructed. Therefore, localizing resistance genes to specific plasmids may be difficult, limiting epidemiological insight. Long-read sequencing will become increasingly popular as costs decline, especially when resolving accurate plasmid structures is the primary goal. This review discusses the application of plasmid classification in WGS-based studies of antibiotic resistance epidemiology; novel in silico plasmid analysis tools are highlighted. Due to the diverse and plastic nature of plasmid genomes, current typing schemes do not classify all plasmids, and identifying conserved, phylogenetically concordant genes for subtyping and phylogenetics is challenging. Analyzing plasmids as nodes in a network that represents gene-sharing relationships between plasmids provides a complementary way to assess plasmid diversity, and allows inferences about horizontal gene transfer to be made

    Azimuthally polarized spatial dark solitons: exact solutions of Maxwell's equations in a Kerr medium

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    Spatial Kerr solitons, typically associated with the standard paraxial nonlinear Schroedinger equation, are shown to exist to all nonparaxial orders, as exact solutions of Maxwell's equations in the presence of vectorial Kerr effect. More precisely, we prove the existence of azimuthally polarized, spatial, dark soliton solutions of Maxwell's equations, while exact linearly polarized (2+1)-D solitons do not exist. Our ab initio approach predicts the existence of dark solitons up to an upper value of the maximum field amplitude, corresponding to a minimum soliton width of about one fourth of the wavelength.Comment: 4 pages, 4 figure

    Pathwise Sensitivity Analysis in Transient Regimes

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    The instantaneous relative entropy (IRE) and the corresponding instanta- neous Fisher information matrix (IFIM) for transient stochastic processes are pre- sented in this paper. These novel tools for sensitivity analysis of stochastic models serve as an extension of the well known relative entropy rate (RER) and the corre- sponding Fisher information matrix (FIM) that apply to stationary processes. Three cases are studied here, discrete-time Markov chains, continuous-time Markov chains and stochastic differential equations. A biological reaction network is presented as a demonstration numerical example
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