3,614 research outputs found
Influence of heat treatment on mechanical properties of 300M steel
Tests show that 300M steel should be austenitized at temperatures above 1,800 deg. F to yield best combintion of strength and thickness. Tempering should be performed at temperatures between 400 and 600 deg.
Quantum versus Semiclassical Description of Selftrapping: Anharmonic Effects
Selftrapping has been traditionally studied on the assumption that
quasiparticles interact with harmonic phonons and that this interaction is
linear in the displacement of the phonon. To complement recent semiclassical
studies of anharmonicity and nonlinearity in this context, we present below a
fully quantum mechanical analysis of a two-site system, where the oscillator is
described by a tunably anharmonic potential, with a square well with infinite
walls and the harmonic potential as its extreme limits, and wherein the
interaction is nonlinear in the oscillator displacement. We find that even
highly anharmonic polarons behave similar to their harmonic counterparts in
that selftrapping is preserved for long times in the limit of strong coupling,
and that the polaronic tunneling time scale depends exponentially on the
polaron binding energy. Further, in agreement, with earlier results related to
harmonic polarons, the semiclassical approximation agrees with the full quantum
result in the massive oscillator limit of small oscillator frequency and strong
quasiparticle-oscillator coupling.Comment: 10 pages, 6 figures, to appear in Phys. Rev.
Characterization of the Interaction between the Herpes Simplex Virus Type I Fc Receptor and Immunoglobulin G
Herpes simplex virus type I (HSV-1) virions and HSV-1-infected cells bind to human immunoglobulin G (hIgG) via its Fc region. A complex of two surface glycoproteins encoded by HSV-1, gE and gI, is responsible for Fc binding. We have co-expressed soluble truncated forms of gE and gI in Chinese hamster ovary cells. Soluble gE-gI complexes can be purified from transfected cell supernatants using a purification scheme that is based upon the Fc receptor function of gE-gI. Using gel filtration and analytical ultracentrifugation, we determined that soluble gE-gI is a heterodimer composed of one molecule of gE and one molecule of gI and that gE-gI heterodimers bind hIgG with a 1:1 stoichiometry. Biosensor-based studies of the binding of wild type or mutant IgG proteins to soluble gE-gI indicate that histidine 435 at the CH2-CH3 domain interface of IgG is a critical residue for IgG binding to gE-gI. We observe many similarities between the characteristics of IgG binding by gE-gI and by rheumatoid factors and bacterial Fc receptors such as Staphylococcus aureus protein A. These observations support a model for the origin of some rheumatoid factors, in which they represent anti-idiotypic antibodies directed against antibodies to bacterial and viral Fc receptors
Microstructure and mechanical properties of quenched and tempered 300M steel
Type 300M steel, which is being used for the landing gear on the space shuttle orbiter, was subjected to a wide range of quenched and tempered heat treatments. The plane-strain fracture toughness and the tensile ultimate and yield strengths were evaluated. Cryogenic mechanical properties were obtained for conventionally heat-treated steel. The microstructure of all heat-treated test coupons was studied both optically and by transmission electron microscopy. Fracture surfaces were studied by means of scanning electron microscopy. Results indicate that substantial improvement in toughness with no loss in strength can be accomplished in quenched and tempered steel by austenitizing at 1255 K or higher. Low fracture toughness in conventionally austenitized 300M steel (1144 K) appears to be caused by undissolved precipitates, seen both in the submicrostructure and on the fracture surface, which promote failure by quasi-cleavage. The precipitates appeared to dissolve in the range 1200 to 1255 K
Spectral Properties of Coupled Bose-Einstein Condensates
We investigate the energy spectrum structure of a system of two (identical)
interacting bosonic wells occupied by N bosons within the Schwinger realization
of the angular momentum. This picture enables us to recognize the symmetry
properties of the system Hamiltonian H and to use them for characterizing the
energy eigenstates. Also, it allows for the derivation of the single-boson
picture which is shown to be the background picture naturally involved by the
secular equation for H. After deriving the corresponding eigenvalue equation,
we recast it in a recursive N-dependent form which suggests a way to generate
the level doublets (characterizing the H spectrum) via suitable inner
parameters. Finally, we show how the presence of doublets in the spectrum
allows to recover, in the classical limit, the symmetry breaking effect that
characterizes the system classically.Comment: 8 pages, 3 figures; submitted to Phys. Rev. A. The present extended
form replaces the first version in the letter forma
Phenomenology of Neutrino Oscillations
The phenomenology of solar, atmospheric, supernova and laboratory neutrino
oscillations is described. Analytical formulae for matter effects are reviewed.
The results from oscillations are confronted with neutrinoless double beta
decay.Comment: 11 pages, 2 figures, latex, Plenary talk given at Workshop in High
Energy Particle Physics-6, Chennai, Indi
Observation of beta decay of In-115 to the first excited level of Sn-115
In the context of the LENS R&D solar neutrino project, the gamma spectrum of
a sample of metallic indium was measured using a single experimental setup of 4
HP-Ge detectors located underground at the Gran Sasso National Laboratories
(LNGS), Italy. A gamma line at the energy (497.48 +/- 0.21) keV was found that
is not present in the background spectrum and that can be identified as a gamma
quantum following the beta decay of In-115 to the first excited state of Sn-115
(9/2+ --> 3/2+). This decay channel of In-115, which is reported here for the
first time, has an extremely low Q-value, Q = (2 +/- 4) keV, and has a much
lower probability than the well-known ground state-ground state transition,
being the branching ratio b = (1.18 +/- 0.31) 10^-6. This could be the beta
decay with the lowest known Q-value. The limit on charge non-conserving beta
decay of In-115 is set at 90% C.L. as tau > 4.1 10^20 y.Comment: 19 pages, 5 figures, 2 table
How essential are unstructured clinical narratives and information fusion to clinical trial recruitment?
Electronic health records capture patient information using structured
controlled vocabularies and unstructured narrative text. While structured data
typically encodes lab values, encounters and medication lists, unstructured
data captures the physician's interpretation of the patient's condition,
prognosis, and response to therapeutic intervention. In this paper, we
demonstrate that information extraction from unstructured clinical narratives
is essential to most clinical applications. We perform an empirical study to
validate the argument and show that structured data alone is insufficient in
resolving eligibility criteria for recruiting patients onto clinical trials for
chronic lymphocytic leukemia (CLL) and prostate cancer. Unstructured data is
essential to solving 59% of the CLL trial criteria and 77% of the prostate
cancer trial criteria. More specifically, for resolving eligibility criteria
with temporal constraints, we show the need for temporal reasoning and
information integration with medical events within and across unstructured
clinical narratives and structured data.Comment: AMIA TBI 2014, 6 page
Distributed Change Detection via Average Consensus over Networks
Distributed change-point detection has been a fundamental problem when
performing real-time monitoring using sensor-networks. We propose a distributed
detection algorithm, where each sensor only exchanges CUSUM statistic with
their neighbors based on the average consensus scheme, and an alarm is raised
when local consensus statistic exceeds a pre-specified global threshold. We
provide theoretical performance bounds showing that the performance of the
fully distributed scheme can match the centralized algorithms under some mild
conditions. Numerical experiments demonstrate the good performance of the
algorithm especially in detecting asynchronous changes.Comment: 15 pages, 8 figure
Interacting classical dimers on the square lattice
We study a model of close-packed dimers on the square lattice with a nearest
neighbor interaction between parallel dimers. This model corresponds to the
classical limit of quantum dimer models [D.S. Rokhsar and S.A. Kivelson, Phys.
Rev. Lett.{\bf 61}, 2376 (1988)]. By means of Monte Carlo and Transfer Matrix
calculations, we show that this system undergoes a Kosterlitz-Thouless
transition separating a low temperature ordered phase where dimers are aligned
in columns from a high temperature critical phase with continuously varying
exponents. This is understood by constructing the corresponding Coulomb gas,
whose coupling constant is computed numerically. We also discuss doped models
and implications on the finite-temperature phase diagram of quantum dimer
models.Comment: 4 pages, 4 figures; v2 : Added results on doped models; published
versio
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