637 research outputs found
Dual photochemical replenisher system reduces chemical losses
Dual replenisher system reduces chemical losses and maintains optimum solution concentration during long nonprocessing cycles of photo processing machines. Using a single 3-position switch and solenoid control valves, the system provides instantaneous flow control to each processing tank
A New Prescription for Pain Management in Humans: Does Exercise Dose Matter?
Please refer to the pdf version of the abstract located adjacent to the title
Sleep Disturbances Effect on the Development of Disability Following a Motor Vehicle Collision: A Cohort Study
Purpose: The purpose of this study was to evaluate sleep disturbance and calculate its effect on long-term outcomes for people with whiplash associated disorder (WAD) following a motor vehicle collision (MVC). Methods: A secondary analysis of data for 97 people (females = 72) diagnosed with WAD was collected at 10%. Logistic regression was used to calculate significance and odds ratios (OR) for the variables of age, body mass index (BMI), sex, and sleep disturbance. Results: With logistic regression age and BMI were non-significant factors, however, sex (ê•2 = 9.37, p = 0.025; OR = 4.3) and sleep disturbance (ê•2 = 17.56, p = 0.002; OR 5.4) were significant factors predicting persistent disability for people with WAD. Conclusion: Sleep disturbance has a moderate effect on the development of persistent WAD while no sleep disturbance is associated with recovery. Assessing and managing sleep disturbance in the health care setting may help to reduce some of the burden of chronic WAD
Upper Extremity Strength Characteristics in Female Recreational Tennis Players With and Without Lateral Epicondylalgia
STUDY DESIGN: Descriptive, cross-sectional. OBJECTIVES: To compare static strength characteristics of the upper extremity musculature in female recreational tennis players with lateral epicondylalgia to those of nonsymptomatic tennis players and a control group of women who did not play tennis. BACKGROUND: There is a paucity of research describing the relationship between lateral epicondylalgia and strength characteristics of the upper extremity musculature, despite the functional relationship between the shoulder, elbow, and wrist. METHODS: Sixty-three women were recruited into 3 groups (n = 21 per group): symptomatic tennis players (SIP) with lateral epicondylalgia, nonsymptomatic tennis players, and controls. Data collection was performed during a single session, during which the strength of selected muscle groups of the dominant upper extremity was measured using a combination of force transducers. Strength ratios of selected muscle groups were then calculated. RESULTS: The SIP group reported median pain level of 3/10 on a numeric pain rating scale and a symptom duration of 16 weeks. The SIP group had weaker lower trapezius strength (mean difference, -9.0 N; 95% confidence interval [CI]: -13.5, -4.4) and wrist extensor strength (-12.7 N; 95% CI: -24.4, -1.1), and a higher shoulder internal/external rotation strength ratio (0.19; 95% CI: 0.02, 0.35) and upper/lower trapezius strength ratio (1.32; 95% CI: 0.41, 2.23), compared to those of the nonsymptomatic group. Compared to the control group, the SIP group demonstrated a significantly higher shoulder internal/external rotation strength ratio (0.21; 95% CI: 0.04, 0.38) and wrist flexion/extension strength ratio (0.14; 95% CI: 0.01, 0.27). CONCLUSION: In this group of recreational female tennis players, significant differences in strength and strength ratio characteristics were identified. Although the design of the study precludes establishing a cause-and-effect relationship, the results suggest further study and treatment of the muscle groups of interest
Summer undergraduate research: A new pipeline for pain clinical practice and research
BACKGROUND: Most medical schools fail to provide adequate training of clinicians in the treatment of pain. Similarly, despite the fact that over 1/3 of Americans suffer from chronic pain, National Institutes of Health (NIH) funding for pain represents only ~1 % of the NIH budget. These issues may dissuade students from pursing pain in their clinical and research careers. To address these gaps in training and funding, we argue that exposing students to pain science early in their careers, at the undergraduate level, may be an effective method to develop a pipeline for future pain clinicians and scientists. To highlight our argument, we will describe our recent successful implementation of a cross-disciplinary and community-engaged biomedical summer research program. The Pain Undergraduate Research Experience (PURE) summer program involved both off-site and on-site experiences to expose undergraduate students to the range of careers in the pain field from basic science to clinical practice. The objective of the 10-week long PURE program was to evaluate whether a combination of basic science research, clinical practice visits, and patient interactions would increase student understanding of and exposure to the underlying science of pain. METHODS: A pre-post cohort study was used without a comparison group. Entry and exit surveys were used to evaluate students’ perceptions about pain clinical practice and research, student interest in pain, and student confidence about communicating about pain and doing basic science pain research. RESULTS: Students reported significant increases to a number of questions in the survey. Questions were scored on 5 point Likert scales and there was significant increases in student understanding of what life is like with chronic pain (2.6 vs 4.3 post survey), their confidence in explaining pain to a patient (2.8 vs 4.1) or researcher (2.8 vs 4), and their comfort with pain terminology(2.8 vs 3.9). CONCLUSIONS: With the PURE program, we wanted to entice top undergraduates to consider pain as a future area of study, practice, and/or research. We present a model that can be easily implemented at research universities throughout the United States
Alumni Voices of the African Immersion Experience
In this session, alumni shared their experiences of African immersion while they were students at UD and how that experience has carried with them in their careers and personal lives.https://ecommons.udayton.edu/global_voices_3/1009/thumbnail.jp
Marine cyanobacteria-derived serotonin receptor 2C active fraction induces psychoactive behavioral effects in mice
Context—Marine cyanobacteria offer a robust resource for natural products drug discovery due to the secondary metabolites they produce.
Objective—To identify novel cyanobacterial compounds that exhibit CNS psychoactive effects.
Materials and methods—Cyanobacteria were collected from Las Perlas Archipelago, Panama and subjected to dichloromethane/methanol extraction and fractionation by column chromatography before being screened for affinity against a panel of CNS targets. A 50:50 ethyl acetate:methanol fraction of one cyanobacterial extract (2064H) was subjected to HPLC and the major peak was isolated (2064H3). At a dose of 20 μg per animal, 2064H and 2064H3 were tested in mice using behavioral assays that included the forced swim, open field, and formalin tests.Context—Marine cyanobacteria offer a robust resource for natural products drug discovery due to the secondary metabolites they produce.
Objective—To identify novel cyanobacterial compounds that exhibit CNS psychoactive effects.
Materials and methods—Cyanobacteria were collected from Las Perlas Archipelago, Panama and subjected to dichloromethane/methanol extraction and fractionation by column chromatography before being screened for affinity against a panel of CNS targets. A 50:50 ethyl acetate:methanol fraction of one cyanobacterial extract (2064H) was subjected to HPLC and the major peak was isolated (2064H3). At a dose of 20 μg per animal, 2064H and 2064H3 were tested in mice using behavioral assays that included the forced swim, open field, and formalin tests
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