Неинвазивная лазеротерапия хронических неспецифических воспалителъных заболеваний шейки матки

IMSP Institutul Mamei şi CopiluluiBackground: Traditional treatment of cervical inflammatory diseases usually has consequences like recurrences or evolution to malignancy. The application of an effective method of treatment of chronic inflammatory diseases of the cervix is still a challenge for practicing doctors. Material and methods: To enhance the efficiency of treatment for chronic nonspecific inflammatory diseases of the cervix (cervicitis) the author studied the possibilities of alternative, no medicaments therapy modalities in 252 women (whose mean age was 28,0±1,3 years), by monitoring a set of clinical and laboratory parameters, including the Babes Papanicolau test. Alternative individualized treatment for the above disease was performed by replacing conventional topical treatment using vaginal douches and various beads from the Betadine procedure using non-invasive laser therapy, the authors proposed. Results: It was proved that alternative treatment by laser therapy non-invasive of cervicitis was reasonably effective: recovery occurred in 88,1±3,1% of patients in the comparison group 57,1±5,8% (p<0,01), recurrences were observed in 11,9±8,3% and 42,9±2,0%, respectively (p<0,01). In the procedure using non-invasive laser therapy, we didn’t adverse reactions, intolerance, and allergy, which makes alternative treatment more expedient economically sound, and easy to use the main thing is that doesn’t let transformation of the inflammatory process in malignancy. Conclusion: Proposed method of non-invasive laser therapy is an effective and safe method in the treatment of chronic inflammatory diseases of the cervix. The application of non-invasive laser therapy is one of the prophylaxes measures to prevent cervix cancer.Актуальность: Традиционное лечение воспалительных заболеваний шейки матки, как правило, имеет последствия в виде рецидивов или эволюции в направлении малигнизации. Применение эффективного метода лечения хронических воспалительных заболеваний шейки матки до сих пор провокация для практикующих врачей. Материал и методы: С целъю повышения эффективности лечения хронических неспецифических воспалительных заболеваний шейки матки, в частности цервицита, изученa возможность использования альтернативной немедикаментозной методики у 252 гинекологических больных, средний возраст которых составлял 28,0±1,3 лет, под контролем комплекса клинико-лабораторных показателей, включающих проведение в 100% случаев, до и после лечения, цитологического теста Бабеш-Папаниколау. Альтернативное индивидуализированное лечение указанной патологии осуществляли путем местного введения во влагалище свечей с бетадином сеансами неинвазивной лазеротерапии по методике предложенной автором. Результаты: Доказано что альтернативный метод лечения цервицитов является достаточно эффективным: в 88,1±3,1% случаев наступает выздоровление в сравнении с 57,1±5,8% случаев, пролеченных бетадином (p<0,01). Рецидив в основной группе наступил у 11,9±8,3% пациенток по сравнению с 42,9±2,0% пациенток в группе с традиционным лечением (p<0,01). При проведении сеансов лазеротерапии не отмечалось побочных явлений непереносимости и аллергии, что делает данный метод лечения более целесообразным, экономически выгодным и доступным в применении, и главное, позволяет предотвратить переход воспалительного процесса в злокачественный. Заключение: Предложенный метод неинвазивной лазерной терапии является эффективным и безопасным методом в лечении хронических воспалительных заболеваний шейки матки. Применение неинвазивной лазерной терапии является одной из мер профилактики по предотвращению рака шейки матки

New Aerodynamic Studies of an Adaptive Winglet Application on the Regional Jet CRJ700

This study aims to evaluates how an adaptive winglet during flight can improve aircraft aerodynamic characteristics of the CRJ700. The aircraft geometry was slightly modified to integrate a one-rotation axis adaptive winglet. Aerodynamic characteristics of the new adaptive design were computed using a validated high-fidelity aerodynamic model developed with the open-source code OpenFoam. The aerodynamic model successively uses the two solvers simpleFoam and rhoSimpleFoam based on Reynold Averaged Navier Stokes equations. Characteristics of the adaptive winglet design were studied for 16 flight conditions, representative of climb and cruise usually considered by the CRJ700. The adaptive winglet can increase the lift-to-drag ratio by up to 6.10% and reduce the drag coefficient by up to 2.65%. This study also compared the aerodynamic polar and pitching moment coefficients variations of the Bombardier CRJ700 equipped with an adaptive versus a fixed winglet

Phase Synchronization and Polarization Ordering of Globally-Coupled Oscillators

We introduce a prototype model for globally-coupled oscillators in which each element is given an oscillation frequency and a preferential oscillation direction (polarization), both randomly distributed. We found two collective transitions: to phase synchronization and to polarization ordering. Introducing a global-phase and a polarization order parameters, we show that the transition to global-phase synchrony is found when the coupling overcomes a critical value and that polarization order enhancement can not take place before global-phase synchrony. We develop a self-consistent theory to determine both order parameters in good agreement with numerical results

Evidence of Low-Temperature Superparamagnetism in Mn3O_{3}O_{4}$ Nanoparticle Ensembles

Please refer to the abstract within the main body of the paper

Optimization and design of an aircraft’s morphing wing-tip demonstrator for drag reduction at low speed, Part I – Aerodynamic optimization using genetic, bee colony and gradient descent algorithms

In this paper, an ‘in-house’ genetic algorithm is described and applied to an optimization problem for improving the aerodynamic performances of an aircraft wing tip through upper surface morphing. The algorithm’s performances were studied from the convergence point of view, in accordance with design conditions. The algorithm was compared to two other optimization methods, namely the artificial bee colony and a gradient method, for two optimization objectives, and the results of the optimizations with each of the three methods were plotted on response surfaces obtained with the Monte Carlo method, to show that they were situated in the global optimum region. The optimization results for 16 wind tunnel test cases and 2 objective functions were presented. The 16 cases used for the optimizations were included in the experimental test plan for the morphing wing-tip demonstrator, and the results obtained using the displacements given by the optimizations were evaluated

Flutter analysis of a morphing wing technology demonstrator : numerical simulation and wind tunnel testing

As part of a morphing wing technology project, the flutter analysis of two finite element models and the experimental results of a morphing wing demonstrator equipped with aileron are presented. The finite element models are representing a wing section situated at the tip of the wing; the first model corresponds to a traditional aluminium upper surface skin of constant thickness and the second model corresponds to a composite optimized upper surface skin for morphing capabilities. The two models were analyzed for flutter occurrence and effects on the aeroelastic behaviour of the wing were studied by replacing the aluminium upper surface skin of the wing with a specially developed composite version. The morphing wing model with composite upper surface was manufactured and fitted with three accelerometers to record the amplitudes and frequencies during tests at the subsonic wind tunnel facility at the National Research Council. The results presented showed that no aeroelastic phenomenon occurred at the speeds, angles of attack and aileron deflections studied in the wind tunnel and confirmed the prediction of the flutter analysis on the frequencies and modal displacements

Sorption kinetic study of selenite and selenate onto a high and low pressure aged iron oxide nanomaterial

The sorption of selenite (SeO32−) and selenate (SeO42−) onto Fe3O4 nanomaterials produced by non microwave-assisted or microwave-assisted synthetic techniques was investigated through use of the batch technique. The phase of both synthetic nanomaterials was determined to be magnetite by X-ray diffraction. The average grain sizes of non microwave-assisted and microwave-assisted synthetic Fe3O4 were determined to be 27 and 25 nm, respectively through use of the Scherrer\u27s equation. Sorption of selenite was pH independent in the pH range of 2-6, while sorption of selenate decreased at pH 5 and 6. The addition of Cl− had no significant effect on selenite or selenate binding, while the addition of NO3− only affected selenate binding to the microwave assisted Fe3O4. A decrease of selenate binding to both synthetic particles was observed after the addition of SO42− while selenite binding was not affected. The addition of PO43− beginning at concentrations of 0.1 ppm had the most prominent effect on the binding of both selenite and selenate. The capacities of binding, determined through the use of Langmuir isotherm, were found to be 1923 and 1428 mg Se/kg of non microwave-assisted Fe3O4 and 2380 and 2369 mg Se/kg of microwave-assisted Fe3O4 for selenite and selenate, respectively

Numerical and experimental transition results evaluation for a morphing wing and aileron system

A new wing-tip concept with morphing upper surface and interchangeable conventional and morphing ailerons was designed, manufactured, bench and wind tunnel tested. The development of this wing tip model was performed in the frame of an international CRIAQ project, and the purpose was to demonstrate the wing upper surface and aileron morphing capabilities in improving the wing tip aerodynamic performances. During numerical optimization with ‘in-house’ genetic algorithm software, and during wind tunnel experimental tests, it was demonstrated that the air flow laminarity over the wing skin was promoted, and the laminar flow was extended with up to 9% of the chord. Drag coefficient reduction of up to 9% was obtained when the morphing aileron was introduced