8,358 research outputs found
Satellite stratospheric aerosol measurement validation
The validity of the stratospheric aerosol measurements made by the satellite sensors SAM II and SAGE was tested by comparing their results with each other and with results obtained by other techniques (lider, dustsonde, filter, and impactor). The latter type of comparison required the development of special techniques that convert the quantity measured by the correlative sensor (e.g. particle backscatter, number, or mass) to that measured by the satellite sensor (extinction) and quantitatively estimate the uncertainty in the conversion process. The results of both types of comparisons show agreement within the measurement and conversion uncertainties. Moreover, the satellite uncertainty is small compared to aerosol natural variability (caused by seasonal changes, volcanoes, sudden warmings, and vortex structure). It was concluded that the satellite measurements are valid
A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer. In this study we implanted stents coated with cicaprost, a prostacyclin analogue with a long plasma half-life and antiproliferative effects on vascular smooth muscle cells, into the iliac arteries of rabbits. At 28-day follow-up we compared neointima formation within the stented vessels and vascular function in adjacent vessels, to assess if cicaprost could reduce restenosis without impairing vessel function. Arteries implanted with cicaprost eluting stents had significantly more neointima compared to bare metal stents. In adjacent segments of artery, endothelium-dependent relaxation was impaired by the cicaprost-eluting stent but vasodilation to an endothelium-independent vasodilator was maintained. We conclude that the presence of the polymer and sub-optimal release of cicaprost from the stent may be responsible for the increased neointma and impaired functional recovery of the endothelium observed. Further experiments should be aimed at optimising release of cicaprost and exploring different stent polymer coatings
Evaluation of functions on microcomputers: rational approximation of kth roots
AbstractThis paper describes the implementation of rational approximation algorithms for evaluation of kth roots in short wordlength machines. The emphasis is on maintaining full machine precision in computers that use fixed point, truncated binary arithmetic with at most 16 bits of wordlength. Included is a table of coefficients for evaluation of kth roots on a 16 bit machine with 3 ≤ k ≤ 11
Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3
The enteric pathogen Salmonella enterica serovar Typhimurium causes food poisoning resulting in gastroenteritis. The S. Typhimurium effector Salmonella invasion protein A (SipA) promotes gastroenteritis by functional motifs that trigger either mechanisms of inflammation or bacterial entry. During infection of intestinal epithelial cells, SipA was found to be responsible for the early activation of caspase-3, an enzyme that is required for SipA cleavage at a specific recognition motif that divided the protein into its two functional domains and activated SipA in a manner necessary for pathogenicity. Other caspase-3 cleavage sites identified in S. Typhimurium appeared to be restricted to secreted effector proteins, which indicates that this may be a general strategy used by this pathogen for processing of its secreted effectors
Probing the subshell closure: factor of the Mg(2) state
The first-excited state ~factor of Mg has been measured relative to
the factor of the Mg() state using the high-velocity
transient-field technique, giving . This new measurement is in
strong disagreement with the currently adopted value, but in agreement with the
-shell model using the USDB interaction. The newly measured factor,
along with and systematics, signal the closure of the subshell at . The possibility that precise -factor
measurements may indicate the onset of neutron admixtures in first-excited
state even-even magnesium isotopes below Mg is discussed and the
importance of precise excited-state -factor measurements on ~shell
nuclei with to test shell-model wavefunctions is noted.Comment: 8 pages, 5 figure
Natural Cycles, Gases
The major gaseous components of the exhaust of stratospheric aircraft are expected to be the products of combustion (CO2 and H2O), odd nitrogen (NO, NO2 HNO3), and products indicating combustion inefficiencies (CO and total unburned hydrocarbons). The species distributions are produced by a balance of photochemical and transport processes. A necessary element in evaluating the impact of aircraft exhaust on the lower stratospheric composition is to place the aircraft emissions in perspective within the natural cycles of stratospheric species. Following are a description of mass transport in the lower stratosphere and a discussion of the natural behavior of the major gaseous components of the stratospheric aircraft exhaust
SAM-2 ground-truth plan: Correlative measurements for the Stratospheric Aerosol Measurement-2 (SAM 2) sensor on the Nimbus G satellite
The SAM-2 will fly aboard the Nimbus-G satellite for launch in the fall of 1978 and measure stratospheric vertical profiles of aerosol extinction in high latitude bands. The plan gives details of the location and times for the simultaneous satellite/correlative measurements for the nominal launch time, the rationale and choice of the correlative sensors, their characteristics and expected accuracies, and the conversion of their data to extinction profiles. The SAM-2 expected instrument performance and data inversion results are presented. Various atmospheric models representative of polar stratospheric aerosols are used in the SAM-2 and correlative sensor analyses
Tropospheric Transmissivity Measurements Using the Raman Nitrogen Lidar Technique
LIDAR measurements in Azusa, California, during October 1972, were made in which the backscattered Raman-shifted nitrogen return was ratioed at different altitudes in order to obtain transmissivity. Rawinsonde data from nearby El Monte were used to determine the temperature and nitrogen number density altitude profiles. These data and other meteorological data are compared to the vertical aerosol and transmissivity structure determined by LIDAR. Also data analysis techniques are shown for obtaining q2 (transmissivity) and beta (attenuation coefficient) as a function of altitude
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