1,959 research outputs found
Wire GEM detector
A wire GEM (WGEM) detector with a gas gap between meshes was constructed. The
detector provides the amplification 5x10E5 for the gas mixture of Ar +20% CO2
at atmospheric pressure. As compared with well-known GEM detectors produced by
perforation the plastic plate metalized on both sides the WGEM does not suffer
from breakdowns between its electrodes and the effect of accumulation of
charges on holes walls is absent. As a result the WGEM has high reliability and
stability.Comment: Presented at the RD51 Collaboration Meeting, CERN, November 2009,
submitted to the Prib. Tech. Expe
RETGEM with polyvinylchloride (PVC) electrodes
This paper presents a new design of the RETGEM (Resistive Electrode Thick
GEM) based on electrodes made of a polyvinylchloride material (PVC). Our device
can operate with gains of 10E5 as a conventional TGEM at low counting rates and
as RPC in the case of high counting rates without of the transit to the violent
sparks. The distinct feature of present RETGEM is the absent of the metal
coating and lithographic technology for manufacturing of the protective
dielectric rms. The electrodes from PVC permit to do the holes by a simple
drilling machine. Detectors on a RETGEM basis could be useful in many fields of
an application requiring a more cheap manufacturing and safe operation, for
example, in a large neutrino experiments, in TPC, RICH systems.Comment: Presented at the RD51 Collaboration Meeting, CERN, November 200
"Better Safe than Sorry" - Individual Risk-free Pension Schemes in the European Union - Macroeconomic Benefits, the Mobile Working Citizen's Perspective and Why Nots
Variations between the diverse pension systems in the member states of the European Union hamper labour market mobility, across country borders but also within the countries of the European Union. From a macroeconomic perspective, and in the light of demographic pressure, this paper argues that allowing individual instead of collective pension building would greatly improve labour market flexibility and thus enhance the functioning of the monetary union. I argue that working citizens would benefit, for three reasons, from pension saving in a risk-free savings account. First, citizens would have a clear picture of the accumulation of their own pension savings throughout their working life. Second, they would pay hardly any extra costs and, third, once retired they would not be subject to the whims of government or other pension fund managers. This paper investigates the feasibility of individual pension building under various parameter settings by calculating the pension saved during a working life and the pension dis-saved after retirement. The findings show that there are no reasons why the European Union and individual member states should not allow individual risk-free pension savings accounts. This would have macroeconomic benefits and provide a solid pension provision that can enhance mobility, instead of engaging workers in different mandatory collective pension schemes that exist around in the European Union
Radio Spectral Evolution of an X-ray Poor Impulsive Solar Flare: Implications for Plasma Heating and Electron Acceleration
We present radio and X-ray observations of an impulsive solar flare that was
moderately intense in microwaves, yet showed very meager EUV and X-ray
emission. The flare occurred on 2001 Oct 24 and was well-observed at radio
wavelengths by the Nobeyama Radioheliograph (NoRH), the Nobeyama Radio
Polarimeters (NoRP), and by the Owens Valley Solar Array (OVSA). It was also
observed in EUV and X-ray wavelength bands by the TRACE, GOES, and Yohkoh
satellites. We find that the impulsive onset of the radio emission is
progressively delayed with increasing frequency relative to the onset of hard
X-ray emission. In contrast, the time of flux density maximum is progressively
delayed with decreasing frequency. The decay phase is independent of radio
frequency. The simple source morphology and the excellent spectral coverage at
radio wavelengths allowed us to employ a nonlinear chi-squared minimization
scheme to fit the time series of radio spectra to a source model that accounts
for the observed radio emission in terms of gyrosynchrotron radiation from
MeV-energy electrons in a relatively dense thermal plasma. We discuss plasma
heating and electron acceleration in view of the parametric trends implied by
the model fitting. We suggest that stochastic acceleration likely plays a role
in accelerating the radio-emitting electrons.Comment: 22 pages, 10 figure
Radio Emission and Particle Acceleration in SN 1993J
The radio light curves of SN 1993J are found to be well fit by a synchrotron
spectrum, suppressed by external free-free absorption and synchrotron
self-absorption. A standard r^-2 circumstellar medium is assumed, and found to
be adequate. The magnetic field and number density of relativistic electrons
behind the shock are determined. The strength of the magnetic field argues
strongly for turbulent amplification behind the shock. The ratio of the
magnetic and thermal energy density behind the shock is ~0.14. Synchrotron and
Coulomb cooling dominate the losses of the electrons. The injected electron
spectrum has a power law index -2.1, consistent with diffusive shock
acceleration, and the number density scales with the thermal electron energy
density. The total energy density of the relativistic electrons is, if
extrapolated to gamma ~ 1, ~ 5x10^-4 of the thermal energy density. The
free-free absorption required is consistent with previous calculations of the
circumstellar temperature of SN 1993J, T_e ~ (2-10)x10^5 K. The relative
importance of free-free absorption, Razin suppression, and the synchrotron
self-absorption effect for other supernovae are briefly discussed. Guidelines
for the modeling and interpretation of VLBI observations are given.Comment: accepted for Ap.
Host-cell dependent role of phosphorylated keratin 8 during influenza A/NWS/33 virus (H1N1) infection in mammalian cells
In this study, we investigated the involvement of keratin 8 during human influenza A/NWS/33 virus (H1N1) infection in semi-permissive rhesus monkey-kidney (LLC-MK2) and permissive human type II alveolar epithelial (A549) cells. In A549 cells, keratin 8 showed major expression and phosphorylation levels. Influenza A/NWS/33 virus was able to subvert keratin 8 structural organization at late stages of infection in both cell models, promoting keratin 8 phosphorylation in A549 cells at early phases of infection. Accordingly, partial colocalizations of the viral nucleoprotein with keratin 8 and its phosphorylated form were assessed by confocal microscopy at early stages of infection in A549 cells. The employment of chemical activators of phosphorylation resulted in structural changes as well as increased phosphorylation of keratin 8 in both cell models, favoring the influenza A/NWS/33 virus's replicative efficiency in A549 but not in LLC-MK2 cells. In A549 and human larynx epidermoid carcinoma (HEp-2) cells inoculated with respiratory secretions from pediatric patients positive for, respectively, influenza A virus or respiratory syncytial virus, the keratin 8 phosphorylation level had increased only in the case of influenza A virus infection. The results obtained suggest that in A549 cells the influenza virus is able to induce keratin 8 phosphorylation thereby enhancing its replicative efficiency
Changes in gene DNA methylation and expression networks accompany caste specialization and age-related physiological changes in a social insect
Social insects provide systems for studying epigenetic regulation of phenotypes, particularly with respect to differentiation of reproductive and worker castes, which typically arise from a common genetic background. The role of gene expression in caste specialization has been extensively studied, but the role of DNA methylation remains controversial. Here, we perform well replicated, integrated analyses of DNA methylation and gene expression in brains of an ant (Formica exsecta) with distinct female castes using traditional approaches (tests of differential methylation) combined with a novel approach (analysis of co-expression and co-methylation networks). We found differences in expression and methylation profiles between workers and queens at different life stages, as well as some overlap between DNA methylation and expression at the functional level. Large portions of the transcriptome and methylome are organized into "modules" of genes, some significantly associated with phenotypic traits of castes and developmental stages. Several gene co-expression modules are preserved in co-methylation networks, consistent with possible regulation of caste-specific gene expression by DNA methylation. Surprisingly, brain co-expression modules were highly preserved when compared with a previous study that examined whole-body co-expression patterns in 16 ant species, suggesting that these modules are evolutionarily conserved and for specific functions in various tissues. Altogether, these results suggest that DNA methylation participates in regulation of caste specialization and age-related physiological changes in social insects.Peer reviewe
Late-stage tectonic evolution of the Al-Hajar Mountains, Oman: New constraints from Palaeogene sedimentary units and low-temperature thermochronometry
Mountain building in the Al-Hajar Mountains (NE Oman) occurred during two major shortening stages, related to the convergence between Africa-Arabia and Eurasia, separated by nearly 30 Ma of tectonic quiescence. Most of the shortening was accommodated during the Late Cretaceous, when northward subduction of the Neo-Tethys Ocean was followed by the ophiolites obduction on top of the former Mesozoic margin. This shortening event lasted until the latest Santonian - early Campanian. Maastrichtian to Eocene carbonates unconformably overlie the eroded nappes and seal the Cretaceous foredeep. These neo-autochthonous post-nappe sedimentary rocks were deformed, along with the underlying Cretaceous tectonic pile, during the second shortening event, itself including two main exhumation stages. In this study we combine remotely sensed structural data, seismic interpretation, field-based structural investigations and apatite (U-Th)/He (AHe) cooling ages to obtain new insights into the Cenozoic deformation stage. Seismic interpretation indicates the occurrence of a late Eocene flexural basin, later deformed by an Oligocene thrusting event, during which the post-nappe succession and the underlying Cretaceous nappes of the internal foredeep were uplifted. This stage was followed by folding of the post-nappe succession during the Miocene. AHe data from detrital siliciclastic deposits in the frontal area of the mountain chain provide cooling ages spanning from 17.3 to 42 Ma, consistent with available data for the structural culminations of Oman. Our work points out how renewal of flexural subsidence in the foredeep and uplift of the mountain belt were coeval processes, followed by layer-parallel shortening preceding final fold amplification
Low-mass e+e- pair production in 158 A GeV Pb-Au collisions at the CERN SPS, its dependence on multiplicity and transverse momentum
We report a measurement of low-mass electron pairs observed in 158
GeV/nucleon Pb-Au collisions. The pair yield integrated over the range of
invariant masses 0.2 < m < 2.0 GeV is enhanced by a factor of 3.5 +/- 0.4
(stat) +/- 0.9 (syst) over the expectation from neutral meson decays. As
observed previously in S-Au collisions, the enhancement is most pronounced in
the invariant-mass region 300-700 MeV. For Pb-Au we find evidence for a strong
increase of the enhancement with centrality. In addition, we show that the
enhancement covers a wide range in transverse momentum, but is largest at the
lowest observed pt.Comment: 17 pages, 4 figures, submitted to Phys.Lett.
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