177 research outputs found

    Problems of attracting adult populationto implementation of the regulations of the all-russian sports complex "Ready for labor and defense"

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    The article deals with the problem of popularizing the GTO complex among the adult population. According to the plan for the implementation of the All-Russian sports complex “Ready for Labor and Defense”, from 2018 the standards of the Complex should be met en masse, by all categories of the population, but the question arises, why does the percentage of the adult population involved remain extremely low? The purpose of this study is to identify the main causes of insufficient participation of adults in the implementation of the standards of complex “Ready for Labor and Defense”. Based on the analysis of modern publications, statistical materials and regulatory documents, we have identified several reasons for the insufficient participation of adults in the implementation of standards.В статье рассмотрена проблема популяризации комплекса ГТО среди взрослого населения

    Drop motion during mass transfer accompanied by interphase convection

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    The article deals with the experimental study of the mass transfer of acetic acid from the dispersed phase (butyl acetate) to the continuous phase (water). The experiments were carried out on a laboratory column with single floating drops. The presence of the Marangoni effect during the movement of drops and its influence on the trajectories of movement of drops and the kinetics of mass transfer during extraction are shown. The influence of the Marangoni effect is most clearly observed when the driving force of the process is 0.1...0.2 mol/l

    Leshy’s “Wardrobe” (by Material of Perm Region Russian Mythological Texts)

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    The article deals with folk ideas about leshy’s clothes. The material included mythological texts from the archives of the Perm State National Research University and folklore and ethnographic collections of the Perm region. The authors proceed from the position that clothing within the traditional culture is perceived as a semiotic system that provides a variety of information about a person: indicates gender, age, family status. The paper shows that the interpretation of clothing as a cultural code is projected on the inhuman, demonic world. It is proved that leshy’s clothing is also semiotically significant: firstly, it helps to emphasize the sex of the character and some of “social” characteristics (for example, “married” female leshy wears a handkerchief), and secondly, it marks the character’s belonging to the demonic world (at the same time certain items of clothing (sheepskin coat, coats in summer, elements of a military wardrobe, high hat), the color of suit (red, black or white), as well as the lack of necessary items of clothing, for example shoes can be considered as a sign of the “inhuman” nature of leshy. Particular attention is paid to the nominative combinations that describe leshy, which include the names of garments. The analysis shows that the elements of such combinations are usually the designations of such items of clothing, which are “standard” for men’s and women’s clothing. It is established that on the territory of the Perm region there is a tendency to “modernization” of the “wardrobe” minimum of leshy

    An analysis of trends and determinants of health insurance and healthcare utilisation in the Russian population between 2000 and 2004: the 'inverse care law' in action

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    BACKGROUND: The break-up of the USSR brought considerable disruption to health services in Russia. The uptake of compulsory health insurance rose rapidly after its introduction in 1993. However, by 2000 coverage was still incomplete, especially amongst the disadvantaged. By this time, however, the state health service had become more stable, and the private sector was growing. This paper describes subsequent trends and determinants of healthcare insurance coverage in Russia, and its relationship with health service utilisation, as well as the role of the private sector. METHODS: Data were from the Russia Longitudinal Monitoring Survey, an annual household panel survey (2000-4) from 38 centres across the Russian Federation. Annual trends in insurance coverage were measured (2000-4). Cross-sectional multivariate analyses of the determinants of health insurance and its relationship with health care utilisation were performed in working-age people (18-59 years) using 2004 data. RESULTS: Between 2000 and 2004, coverage by the compulsory insurance scheme increased from 88% to 94% of adults; however 10% of working-age men remained uninsured. Compulsory health insurance coverage was lower amongst the poor, unemployed, unhealthy and people outside the main cities. The uninsured were less likely to seek medical help for new health problems. 3% of respondents had supplementary (private) insurance, and rising utilisation of private healthcare was greatest amongst the more educated and wealthy. CONCLUSION: Despite high population insurance coverage, a multiply disadvantaged uninsured minority remains, with low utilisation of health services. Universal insurance could therefore increase access, and potentially contribute to reducing avoidable healthcare-related mortality. Meanwhile, the socioeconomically advantaged are turning increasingly to a growing private sector

    Comparative Evaluation of Biomechanical Characteristics of Acellular Dermal Matrix for Hernioplasty

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    Background. With the introduction of synthetic mesh implants into clinical practice, the recurrence rate of postoperative ventral hernias was signifi cantly reduced. The extensive use of synthetic implants led to the development of specifi c complications. The development of biological implants, based on extensively purifi ed decellularized collagen matrix of xenogeneic origin is highly relevant due to the fact that, unlike synthetic analogues, they have a biological origin and biodegrade in a natural way, gradually being replaced with newly formed connective tissue. The use of bioprostheses reduces the risk of complications.Objectives. To conduct a comparative evaluation of the biomechanical characteristics of acellular dermal matrix, obtained by detergent-enzymatic decellularization, and commercially distributed Permacol™ matrix.Methods. Acellular dermal matrix (ADM) was created by using samples of native skin of pig of Landras breed aged 4 months. The dermis was processed by means of detergent-enzymatic method. In order to evaluate and compare the mechanical properties of acellular dermal matrix, the biological samples were divided into 2 groups of 15 samples each. The fi rst group included acellular dermal matrix samples, the second group — native samples of pigs unprocessed dermis. The control group consisted of samples of PermacolTM Surgical Implant, xenotransplant for hernioplasty approved for use in the Russian Federation (Covidien, France). All samples were tested wet using universal testing instrument Instron 1122. MedCalc Statistical Software (Belgium) was used for statistical processing of the study results.Results. In the present study, pig dermis was processed using a detergent-enzymatic method to produce ADM. Routine histological examination confi rmed the removal of all cellular elements, and at the same time it was proven that the native structure of the dermis remained intact during its processing. The mechanical characteristics of xenogenic ADM were further determined. Its tensile strength was 9.1 ± 0.6 MPa (910 N/cm2 ), elongation to break was 21.1 ± 2.3%, and elastic modulus was 50.0 ± 1.6 MPa. These characteristics largely corresponded to the strength characteristics of native pig dermis and far exceeded the necessary physiological parameters. PermacolTM control was tested in two directions (longitudinal and transverse). In the longitudinal direction, the sample had higher mechanical characteristics: strength — 12.0 ± 1.7 MPa, elongation to break — 29.7 ± 2.4%, stiffness modulus — 47.2 ± 6.5 MPa. In the transverse direction, all indicators were 1.5–2 times lower.Conclusion. The developed xenogeneic biological implant in the form of ADM demonstrates rather good characteristics of plasticity, tensile strength and elasticity, to be used as a biological endoprosthesis for plasty of hernia defects of the abdominal wall of any size and shape

    Comparative analysis of local stimulation methods of reparative osteogenesis

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    Objective To determine the ratio of the main growth factors when using various methods of local stimulation of reparative osteogenesis.Material and methods The study consisted of two parts: in the first part a comparative analysis of the content of growth factors by ELISA was carried out (PDGF – platelet derived growth factor, TGF – transforming growth factor, VEGF – vascular endothelial growth factor, IGF – insulin-like growth factor, BMP6 and BMP7 – morphogenetic proteins 6 and 7), capable of stimulating reparative osteogenesis in blood plasma, plateletrich plasma, red bone marrow and bone autoregenerate. The second part presented the results of approbation of the autoregenerate obtained according to the original method in the framework of an acute experiment on animals.Results The most important cytokines affecting the process of reparative osteogenesis are fibroblast growth factor – FGF1 and bone morphogenetic protein 7 – BMP7. Based on the results of a comparative enzymelinked immunosorbent assay, it has been established that the autoregenerate, obtained by the original method, and a bone marrow aspirate concentrate have the highest osteogenic potential.Conclusion Autoregenerate is an effective and promising means of local stimulation of reparative osteogenesis, and its transplantation is a simple and highly effective procedure

    Морфологический анализ местной тканевой реакции на подкожную имплантацию фрагментов ацеллюлярного дермального матрикса

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    Acellular dermal matrices (ADMs) are gaining popularity as surgical materials for operations on the pelvic organs, as well as in burn therapy and plastic surgery. Evaluation of the biocompatibility of surgical materials is an important and necessary step in the development of new ADMs.The aim of the study was to compare the results of subcutaneous implantation of ADM and native porcine skin in rats.Materials and methods. To obtain ADMs, detergent – enzymatic decellularization was used. On days 7, 14, 21, and 60 after the implantation of ADMs (the experimental group) and native porcine skin (the control group), the animals were removed from the experiment. The histologic sections were stained with hematoxylin – eosin and Masson’s trichrome stain, then an immunohistochemical reaction with antibodies to CD3 and CD68 was performed. Computer morphometry was carried out using the ImageJ software.Results. On day 7 after the implantation, moderate sterile inflammation in the experimental group and pronounced sterile inflammation with eosinophil infiltration in the control group were observed. On day 14 of the experiment, the samples from the experimental group were characterized by a relatively low content of macrophages and T-lymphocytes with insignificant edema and no signs of ADM biodegradation. The control group showed pronounced inflammation, a large number of infiltrating macrophages and T lymphocytes, as well as fragmentation of collagen fibers. On day 21 of the experiment, a thin capsule was formed around ADM, there was a small number of infiltrating T lymphocytes and macrophages, the collagen fibers of the implant were intact. In the samples of the control group, there was pronounced inflammation with the presence of a significant number of lymphocytes and macrophages, as well as fragmentation and vascularization of the implant. On day 60 of the experiment, no inflammatory response was observed around ADM, biodegradation was minimal, and a dense fibrous capsule was formed around the fragment of the native porcine skin.Conclusion. The experimental ADM has low immunogenicity and a low degree of biodegradation, which makes it possible to use it for further research to create efficient surgical material that is safe for use in clinical practice.Ацеллюлярные дермальные матриксы (АДМ) набирают большую популярность в качестве хирургических материалов при операциях на органах малого таза, в ожоговой терапии и пластической хирургии. Проверка биосовместимости материалов является важным и необходимым этапом при разработке новых АДМ.Цель исследования – провести сравнительный анализ результатов подкожной имплантации крысам АДМ и нативной дермы свиньи. Материалы и методы. Для получения АДМ использовали детергентно-энзиматический метод децеллюляризации. Через 7, 14, 21, 60 сут после имплантации АДМ (экспериментальная группа) и нативной дермы свиньи (контрольная группа) животных выводили из эксперимента. Гистологические срезы окрашивали гематоксилином и эозином, трихромом по Массону, выполняли иммуногистохимическую реакцию с антителами к CD3 и CD68. Компьютерную морфометрию проводили с помощью программы ImageJ.Результаты. На 7-е сут в экспериментальной группе отмечалось умеренное асептическое воспаление, в контрольной группе – выраженное асептическое воспаление с эозинофилами в инфильтрате. На 14-е сут в экспериментальной группе показано относительно низкое содержание макрофагов и Т-лимфоцитов с незначительным отеком, без биодеградации АДМ. В контрольной группе выявлено выраженное воспаление, инфильтрация большим количеством макрофагов и Т-лимфоцитов, а также фрагментация коллагеновых волокон. На 21-е сут вокруг АДМ сформировалась тонкая капсула, в инфильтрате малое количество Т-лимфоцитов и макрофагов, коллагеновые волокна имплантата были интактны. В образцах контрольной группы – выраженное воспаление с присутствием значительного количества лимфоцитов и макрофагов, фрагментация и васкуляризация имплантата. На 60-е сут вокруг АДМ воспалительной реакции не наблюдалось, биодеградация была минимальной, вокруг фрагмента нативной дермы свиньи сформировалась плотная фиброзная капсула.Заключение. Разработанный АДМ обладает низкой иммуногенностью и малой степенью биодеградации. Это позволяет использовать данную конструкцию для дальнейших исследований по созданию полноценного хирургического материала, безопасного для применения в клинической практике

    Impact of growing conditions on the gum properties of different genotypes of guar (Cyamopsis tetragonoloba (L.) Taub.)

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    Galactomannan (gum), a water-soluble polysaccharide, is widely used as a gelling agent in liquids, including in the oil and gas industry for hydraulic fracturing. The most effective source of this valuable plant material is seeds of guar (Cyamopsis tetragonoloba (L.) Taub.), a legume crop new for Russia. Although in recent years progress has been made in the selection of guar varieties adapted to the conditions of the Russian Federation, the question of the most appropriate region for the cultivation of this crop remains open. The purpose of the study was to investigate how a region and technology of guar cultivation can affect the main indicators of the final target product: the content and viscosity of guar gum extracted from the seeds of various guar genotypes. To understand this, ecogeographical tests of 13 guar accessions from the VIR collection were conducted at the experimental stations of the Vavilov Institute (VIR), where climatic conditions correspond to the temperature requirements of the crop. To compare the properties of gum extracted from the seeds of various genotypes, a fast-tracked laboratory method was suggested allowing gum extracts to be obtained for assessing their viscosity. The method allows fast screening of the breeding material and selecting guar genotypes with beneficial properties of guar gum which are in demand by the oil industry. Applying the fast laboratory method for assessing the properties of gum in seeds of 13 guar varieties showed that the content and viscosity of gum of the same variety vary greatly depending on growing conditions. The same set of 13 guar accessions was grown in 2018 at the Volgograd, Astrakhan, Dagestan and Kuban VIR experimental stations. As a result, the maximum viscosity values were obtained for the seeds reproduced at the Astrakhan region, where the guar was grown on irrigated lands. On the other hand, the maximum gum content in the seeds of all accessions was recorded when they were grown in the Volgograd region. The results showed that the guar gum extracted from seeds of guar plants grown in the Russian Federation can be used as a gelling agent in the processes of intensification of oil production by the method of hydraulic fracturing. This experience is new to the Russian Federation

    Outcome in patients perceived as receiving excessive care across different ethical climates : a prospective study in 68 intensive care units in Europe and the USA

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    Whether the quality of the ethical climate in the intensive care unit (ICU) improves the identification of patients receiving excessive care and affects patient outcomes is unknown. In this prospective observational study, perceptions of excessive care (PECs) by clinicians working in 68 ICUs in Europe and the USA were collected daily during a 28-day period. The quality of the ethical climate in the ICUs was assessed via a validated questionnaire. We compared the combined endpoint (death, not at home or poor quality of life at 1 year) of patients with PECs and the time from PECs until written treatment-limitation decisions (TLDs) and death across the four climates defined via cluster analysis. Of the 4747 eligible clinicians, 2992 (63%) evaluated the ethical climate in their ICU. Of the 321 and 623 patients not admitted for monitoring only in ICUs with a good (n = 12, 18%) and poor (n = 24, 35%) climate, 36 (11%) and 74 (12%), respectively were identified with PECs by at least two clinicians. Of the 35 and 71 identified patients with an available combined endpoint, 100% (95% CI 90.0-1.00) and 85.9% (75.4-92.0) (P = 0.02) attained that endpoint. The risk of death (HR 1.88, 95% CI 1.20-2.92) or receiving a written TLD (HR 2.32, CI 1.11-4.85) in patients with PECs by at least two clinicians was higher in ICUs with a good climate than in those with a poor one. The differences between ICUs with an average climate, with (n = 12, 18%) or without (n = 20, 29%) nursing involvement at the end of life, and ICUs with a poor climate were less obvious but still in favour of the former. Enhancing the quality of the ethical climate in the ICU may improve both the identification of patients receiving excessive care and the decision-making process at the end of life
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