3,746 research outputs found

    Combined analysis of KamLAND and Borexino neutrino signals from Th and U decays in the Earth's interior

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    The KamLAND and Borexino experiments have detected electron antineutrinos produced in the decay chains of natural thorium and uranium (Th and U geoneutrinos). We analyze the energy spectra of current geoneutrino data in combination with solar and long-baseline reactor neutrino data, with marginalized three-neutrino oscillation parameters. We consider the case with unconstrained Th and U event rates in KamLAND and Borexino, as well as cases with fewer degrees of freedom, as obtained by successively assuming for both experiments a common Th/U ratio, a common scaling of Th+U event rates, and a chondritic Th/U value. In combination, KamLAND and Borexino can reject the null hypothesis (no geoneutrino signal) at 5 sigma. Interesting bounds or indications emerge on the Th+U geoneutrino rates and on the Th/U ratio, in broad agreement with typical Earth model expectations. Conversely, the results disfavor the hypothesis of a georeactor in the Earth's core, if its power exceeds a few TW. The interplay of KamLAND and Borexino geoneutrino data is highlighted.Comment: 12 pages, including 6 figure

    Geoneutrinos and reactor antineutrinos at SNO+

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    In the heart of the Creighton Mine near Sudbury (Canada), the SNO+ detector is foreseen to observe almost in equal proportion electron antineutrinos produced by U and Th in the Earth and by nuclear reactors. SNO+ will be the first long baseline experiment to measure a reactor signal dominated by CANDU cores (∼\sim55\% of the total reactor signal), which generally burn natural uranium. Approximately 18\% of the total geoneutrino signal is generated by the U and Th present in the rocks of the Huronian Supergroup-Sudbury Basin: the 60\% uncertainty on the signal produced by this lithologic unit plays a crucial role on the discrimination power on the mantle signal as well as on the geoneutrino spectral shape reconstruction, which can in principle provide a direct measurement of the Th/U ratio in the Earth.Comment: 7 pages including 2 figures and 1 table, in XIV International Conference on Topics in Astroparticle and Underground Physics (TAUP 2015) IOP Publishing , published on Journal of Physics: Conference Series 718 (2016) 06200

    Euclid at Threescore Years and Ten: The Twilight of Environmental and Land-Use Regulation?

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    Life, Liberty, and Whose Property lecture given by Loren A. Smith, Chief Judge, United States Court of Federal Claims. Is this the Twilight of Land Use Controls? lecture given by Charles M. Haar, Professor of Law at Harvard University Law. Capture and Counteraction: Self-Help and Environmental Zealots lecture given by James E. Krier, Earl Warren Delano Professor of Law, University of Michigan. Ecology and Aesthetics: Our Future and the Making of Things lecture given by William A. McDonough, Dean and Elson Professor, University of Virginia School of Architecture

    Effects of prosodically modulated sub-phonetic variation on lexical competition

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    Eye movements were monitored as participants followed spoken instructions to manipulate one of four objects pictured on a computer screen. Target words occurred in utterance-medial (e.g., Put the cap next to the square) or utterance-final position (e.g., Now click on the cap). Displays consisted of the target picture (e.g., a cap), a monosyllabic competitor picture (e.g., a cat), a polysyllabic competitor picture (e.g., a captain) and a distractor (e.g., a beaker). The relative proportion of fixations to the two types of competitor pictures changed as a function of the position of the target word in the utterance, demonstrating that lexical competition is modulated by prosodically conditioned phonetic variation

    Teleology and Realism in Leibniz's Philosophy of Science

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    This paper argues for an interpretation of Leibniz’s claim that physics requires both mechanical and teleological principles as a view regarding the interpretation of physical theories. Granting that Leibniz’s fundamental ontology remains non-physical, or mentalistic, it argues that teleological principles nevertheless ground a realist commitment about mechanical descriptions of phenomena. The empirical results of the new sciences, according to Leibniz, have genuine truth conditions: there is a fact of the matter about the regularities observed in experience. Taking this stance, however, requires bringing non-empirical reasons to bear upon mechanical causal claims. This paper first evaluates extant interpretations of Leibniz’s thesis that there are two realms in physics as describing parallel, self-sufficient sets of laws. It then examines Leibniz’s use of teleological principles to interpret scientific results in the context of his interventions in debates in seventeenth-century kinematic theory, and in the teaching of Copernicanism. Leibniz’s use of the principle of continuity and the principle of simplicity, for instance, reveal an underlying commitment to the truth-aptness, or approximate truth-aptness, of the new natural sciences. The paper concludes with a brief remark on the relation between metaphysics, theology, and physics in Leibniz

    Studies of MCP-PMTs in the miniTimeCube neutrino detector

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    This report highlights two different types of cross-talk in the photodetectors of the miniTimeCube neutrino experiment. The miniTimeCube detector has 24 8×88 \times 8-anode Photonis MCP-PMTs Planacon XP85012, totalling 1536 individual pixels viewing the 2-liter cube of plastic scintillator

    Imaging the Earth's Interior: the Angular Distribution of Terrestrial Neutrinos

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    Decays of radionuclides throughout the Earth's interior produce geothermal heat, but also are a source of antineutrinos. The (angle-integrated) geoneutrino flux places an integral constraint on the terrestrial radionuclide distribution. In this paper, we calculate the angular distribution of geoneutrinos, which opens a window on the differential radionuclide distribution. We develop the general formalism for the neutrino angular distribution, and we present the inverse transformation which recovers the terrestrial radioisotope distribution given a measurement of the neutrino angular distribution. Thus, geoneutrinos not only allow a means to image the Earth's interior, but offering a direct measure of the radioactive Earth, both (1) revealing the Earth's inner structure as probed by radionuclides, and (2) allowing for a complete determination of the radioactive heat generation as a function of radius. We present the geoneutrino angular distribution for the favored Earth model which has been used to calculate geoneutrino flux. In this model the neutrino generation is dominated by decays in the Earth's mantle and crust; this leads to a very ``peripheral'' angular distribution, in which 2/3 of the neutrinos come from angles > 60 degrees away from the downward vertical. We note the possibility of that the Earth's core contains potassium; different geophysical predictions lead to strongly varying, and hence distinguishable, central intensities (< 30 degrees from the downward vertical). Other uncertainties in the models, and prospects for observation of the geoneutrino angular distribution, are briefly discussed. We conclude by urging the development and construction of antineutrino experiments with angular sensitivity. (Abstract abridged.)Comment: 25 pages, RevTeX, 7 figures. Comments welcom

    Bacterial Death Results from Mutations Made in Translocation Peptide of Leucyl-tRNA Synthetase

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    The family of aminoacyl-tRNA synthetases (aaRSs) ensures the fidelity of translation through providing a pool of correctly aminoacylated tRNA products that become incorporated by the ribosome. Leucyl-tRNA synthetase (LeuRS) has two functionally separate domains, one is the aminoacylation domain and the other is the CP1 editing domain. LeuRS can aminoacylate noncognate amino acids, therefore it relies on the CP1 editing domain to hydrolyze misaminoacylated tRNA products before they are released from the enzyme. The LeuRS enzyme must undergo a structural transition state in its reaction cycle in order to translocate the 3\u27 acceptor stem of tRNA 30 Ã… from the aminoacylation active site to the CP1 domain hydrolytic active site. The translocation event is difficult to study, but we believe that we have generated mutations within LeuRS that alter the translocation event of tRNA. The mutations that we have generated lead to bacterial death in Escherichia coli (E. coli). Circular dichorism experiments indicate that our mutations do not significantly alter the secondary structure of LeuRS. In vitro biochemical studies demonstrate that these mutations reduce the rates of aminoacylation and hydrolysis, while also displaying misaminoacylation activity. We attribute these biochemical findings to the resulting bacterial death that is caused by these mutation

    Bacterial Death Results from Mutations Made in Translocation Peptide of Leucyl-tRNA Synthetase

    Get PDF
    The family of aminoacyl-tRNA synthetases (aaRSs) ensures the fidelity of translation through providing a pool of correctly aminoacylated tRNA products that become incorporated by the ribosome. Leucyl-tRNA synthetase (LeuRS) has two functionally separate domains, one is the aminoacylation domain and the other is the CP1 editing domain. LeuRS can aminoacylate noncognate amino acids, therefore it relies on the CP1 editing domain to hydrolyze misaminoacylated tRNA products before they are released from the enzyme. The LeuRS enzyme must undergo a structural transition state in its reaction cycle in order to translocate the 3\u27 acceptor stem of tRNA 30 Ã… from the aminoacylation active site to the CP1 domain hydrolytic active site. The translocation event is difficult to study, but we believe that we have generated mutations within LeuRS that alter the translocation event of tRNA. The mutations that we have generated lead to bacterial death in Escherichia coli (E. coli). Circular dichorism experiments indicate that our mutations do not significantly alter the secondary structure of LeuRS. In vitro biochemical studies demonstrate that these mutations reduce the rates of aminoacylation and hydrolysis, while also displaying misaminoacylation activity. We attribute these biochemical findings to the resulting bacterial death that is caused by these mutation
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