The first study of 54 new eccentric eclipsing binaries in our Galaxy

We present an analysis of the apsidal motion and light curve parameters of 54 galactic Algol-type binaries never before studied. This is the first analysis of such a large sample of eccentric eclipsing binaries in our Galaxy, and has enabled us to identify several systems that are worthy of further study. Bringing together data from various databases and surveys, supplemented with new observations, we have been able to trace the long-term evolution of the eccentric orbit over durations extending back up to several decades. Our present study explores a rather different sample of stars to those presented in the previously published catalogue of eccentric eclipsing binaries by Bulut & Demircan (2007), sampling to fainter magnitudes, covering later spectral types, sensitive to different orbital periods with more than 50% of our systems having periods longer than 6 days. The typical apsidal motion in the sample is rather slow (mostly of order of centuries long), although in some cases this is less than 50 years. All of the systems, except one, have eccentricities less than 0.5, with an average value of 0.23. Several of the stars also show evidence for additional period variability. In particular we can identify three systems in the sample, HD 44093, V611 Pup, and HD 313631, which likely represent relativistic apsidal rotators

A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus.

A combined proteomics and metabolomics approach was utilised to advance the identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here, implementation of a shotgun proteomic strategy led to the identification of non-redundant mycelial proteins (n = 414) from A. fumigatus including proteins typically under-represented in 2-D proteome maps: proteins with multiple transmembrane regions, hydrophobic proteins and proteins with extremes of molecular mass and pI. Indirect identification of secondary metabolite cluster expression was also achieved, with proteins (n = 18) from LaeA-regulated clusters detected, including GliT encoded within the gliotoxin biosynthetic cluster. Biochemical analysis then revealed that gliotoxin significantly attenuates H2O2-induced oxidative stress in A. fumigatus (p>0.0001), confirming observations from proteomics data. A complementary 2-D/LC-MS/MS approach further elucidated significantly increased abundance (p<0.05) of proliferating cell nuclear antigen (PCNA), NADH-quinone oxidoreductase and the gliotoxin oxidoreductase GliT, along with significantly attenuated abundance (p<0.05) of a heat shock protein, an oxidative stress protein and an autolysis-associated chitinase, when gliotoxin and H2O2 were present, compared to H2O2 alone. Moreover, gliotoxin exposure significantly reduced the abundance of selected proteins (p<0.05) involved in de novo purine biosynthesis. Significantly elevated abundance (p<0.05) of a key enzyme, xanthine-guanine phosphoribosyl transferase Xpt1, utilised in purine salvage, was observed in the presence of H2O2 and gliotoxin. This work provides new insights into the A. fumigatus proteome and experimental strategies, plus mechanistic data pertaining to gliotoxin functionality in the organism

Global Matrix 4.0 Physical Activity Report Card Grades for Children and Adolescents: Results and Analyses From 57 Countries

Background: The Global Matrix 4.0 on physical activity (PA) for children and adolescents was developed to achieve a comprehensive understanding of the global variation in children’s and adolescents’ (5–17 y) PA, related measures, and key sources of influence. The objectives of this article were (1) to summarize the findings from the Global Matrix 4.0 Report Cards, (2) to compare indicators across countries, and (3) to explore trends related to the Human Development Index and geo-cultural regions. Methods: A total of 57 Report Card teams followed a harmonized process to grade the 10 common PA indicators. An online survey was conducted to collect Report Card Leaders’ top 3 priorities for each PA indicator and their opinions on how the COVID-19 pandemic impacted child and adolescent PA indicators in their country. Results: Overall Physical Activity was the indicator with the lowest global average grade (D), while School and Community and Environment were the indicators with the highest global average grade (C+). An overview of the global situation in terms of surveillance and prevalence is provided for all 10 common PA indicators, followed by priorities and examples to support the development of strategies and policies internationally. Conclusions: The Global Matrix 4.0 represents the largest compilation of children’s and adolescents’ PA indicators to date. While variation in data sources informing the grades across countries was observed, this initiative highlighted low PA levels in children and adolescents globally. Measures to contain the COVID-19 pandemic, local/international conflicts, climate change, and economic change threaten to worsen this situation

An Evaluation of Policies Promoting Physical Activity among Filipino Youth

Government is key to promoting physical activity at the population level through policy. The government was one of the physical activity indicators graded for the 2022 Philippine Physical Activity Report Card based on ten physical activity-related policies. This study aimed to evaluate the scope of the policies and to update these policies. Philippine government databases were searched for policies using physical activity-related key terms. Policies found were evaluated using the Wales Active Healthy Kids scoring rubric. The overall grade was converted to a letter grade based on the Global Matrix 4.0 grading system. The authors analyzed the policies’ scope and implications to practice and policy. Seven additional policies were found. Considering all 17 policies, the government indicator grade is now A- from the preliminary grade of B. The scope covers promoting physical activity mainly through sports participation and active transport among students, student-athletes, persons with disabilities, and the general population in school and community settings. The gap between government and overall physical activity (F) scores suggests the need for a comprehensive physical activity plan promoting various forms of physical activity and reducing sedentary behavior among all Filipino youth and across various settings. Crucial to achieving change is a well-coordinated, whole-of-systems approach to promoting active healthy lifestyles

A 10-moment fluid numerical solver of plasma with sheaths in a Hall Effect Thruster

International audienceElectric propulsion can reach higher exhaust velocities compared to chemical systems and thus result in lower propellant mass requirements. Among the different electric propulsion systems, Hall effect thrusters are used for spatial propulsion since the 1970s. However inside a Hall thruster, complex physical phenomena such as erosion or electron anomalous transport which may lower thruster efficiency and lifetime, are not yet fully understood. Thanks to high performance computing, numerical simulations are now considered for understanding the plasma behavior. With the renewed interest for such electric propulsion to supply small satellites, numerical solvers able to predict accurately the real thruster efficiency have become crucial for industry. This paper presents the approach used and first validation tests of such a solver. The AVIP code solves plasma equations in complex industrial geometries using an unstructured parallel-efficient 3D fluid methodology. AVIP also includes a Particle-In-Cell (PIC) solver used as a reference for validation. While full 3D PIC simulations of a Hall thruster still require unaffor-dable computational time, fluid models provide in a reasonable time 3D results on the plasma behavior inside the discharge channel. In this category, standard drift-diffusion models [1-3] are fast and robust but at the cost of strong hypotheses and simplifications. In particular such models do not describe explicitly the sheath formation in the vicinity of walls and often use analytical models instead. They are limited to simple configurations and only provide a first insight into plasma complex phenomena. The present approach includes a more detailed two-fluid plasma model without drift-diffusion approximation. After the description of the formulation and main features of the solver, the paper focuses on wall boundary conditions which are crucial for the formation of sheaths. It is demonstrated in particular that a vacuum boundary condition is not adapted to fit PIC results. A boundary condition based on wall thermal fluxes is more realistic. The mesh resolution is also found to be critical. The simulation methodology is finally applied to a 2D simulation of a typical Hall effect thruster in order to observe the plasma properties inside the discharge chamber