Limits from Weak Gravity Conjecture on Dark Energy Models

The weak gravity conjecture has been proposed as a criterion to distinguish the landscape from the swampland in string theory. As an application in cosmology of this conjecture, we use it to impose theoretical constraint on parameters of two types of dark energy models. Our analysis indicates that the Chaplygin-gas-type models realized in quintessence field are in the swampland, whereas the $a$ power-low decay model of the variable cosmological constant can be viable but the parameters are tightly constrained by the conjecture.Comment: Revtex4, 8 pages, 5 figures; References, minor corrections in content, and acknowledgement adde

Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data

Next-generation sequencing (NGS) technologies have matured considerably since their introduction and a focus has been placed on developing sophisticated analytical tools to deal with the amassing volumes of data. Chromatin immunoprecipitation sequencing (ChIP-seq), a major application of NGS, is a widely adopted technique for examining protein-DNA interactions and is commonly used to investigate epigenetic signatures of diffuse histone marks. These datasets have notoriously high variance and subtle levels of enrichment across large expanses, making them exceedingly difficult to define. Windows-based, heuristic models and finite-state hidden Markov models (HMMs) have been used with some success in analyzing ChIP-seq data but with lingering limitations. To improve the ability to detect broad regions of enrichment, we developed a stochastic Bayesian Change-Point (BCP) method, which addresses some of these unresolved issues. BCP makes use of recent advances in infinite-state HMMs by obtaining explicit formulas for posterior means of read densities. These posterior means can be used to categorize the genome into enriched and unenriched segments, as is customarily done, or examined for more detailed relationships since the underlying subpeaks are preserved rather than simplified into a binary classification. BCP performs a near exhaustive search of all possible change points between different posterior means at high-resolution to minimize the subjectivity of window sizes and is computationally efficient, due to a speed-up algorithm and the explicit formulas it employs. In the absence of a well-established "gold standard" for diffuse histone mark enrichment, we corroborated BCP's island detection accuracy and reproducibility using various forms of empirical evidence. We show that BCP is especially suited for analysis of diffuse histone ChIP-seq data but also effective in analyzing punctate transcription factor ChIP datasets, making it widely applicable for numerous experiment types

Can the Lepton Flavor Mixing Matrix Be Symmetric?

Current neutrino oscillation data indicate that the 3x3 lepton flavor mixing matrix V is likely to be symmetric about its V_{e3}-V_{\mu 2}-V_{\tau 1} axis. This off-diagonal symmetry corresponds to three pairs of {\it congruent} unitarity triangles in the complex plane. Terrestrial matter effects can substantially modify the genuine CP-violating parameter and off-diagonal asymmetries of V in realistic long-baseline experiments of neutrino oscillations.Comment: RexTex 14 pages (4 PS figures). More discussions adde

More Straightforward Extraction of the Fundamental Lepton Mixing Parameters from Long-Baseline Neutrino Oscillations

We point out the simple reversibility between the fundamental neutrino mixing parameters in vacuum and their effective counterparts in matter. The former can therefore be expressed in terms of the latter, allowing more straightforward extraction of the genuine lepton mixing quantities from a variety of long-baseline neutrino oscillation experiments. In addition to the parametrization-independent results, we present the formulas based on the standard parametrization of the lepton flavor mixing matrix and give a typical numerical illustration.Comment: RevTex 10 pages. Minor changes. Phys. Rev. D in printin

Approximate Analytical Equations for the Stirrer Angular Correlation in a Reverberation Chamber

IEEE In a reverberation chamber (RC), the angular correlation coefficient of a stirrer is an important parameter. It has been used to evaluate the performance of a stirrer or to estimate the number of independent samples in a measurement. In the previous work, the angular correlation coefficient (ACC) was evaluated numerically and no analytical equation was proposed. In this study, we propose an approximate analytical equation to fit the measured angular correlation that shows good agreements with measurement results. General properties of ACC are explored with physical insights; the equivalency of the mean value of the angular correlation and the $K$-factor is revealed. This study provides further understandings on the control of the stirrer angular correlation and the $K$-factor in an RC