The pick-up of cometary protons by the solar wind

The High Energy Range Spectrometer (HERS) of the Ion Mass Spectrometer on the Giotto spacecraft measured the 3-dimensional distribution of picked-up cometary protons over a distance of approximately 8 million km upstream of the bow shock of Comet Halley. The protons were observed to be elastically scattered out of their original cycloidal trajectories such that they were nonuniformly distributed over a spherical shell in velocity space. The shell radius (relative to its expected radius) and thickness increased as the bow shock was approached. Downstream of the shock, the cometary protons could not be distinguished from the heated solar wind protons

The development, implementation and evaluation of a school-based intervention to promote fruit and vegetable intake among 10-13 year-old European schoolchildren

This thesis describes the development, implementation and evaluation of a school-based intervention to promote fruit and vegetable intake among 10-13 year-old European schoolchildren. The first part of the thesis addresses two determinant studies, a qualitative and a quantitative study, aimed at gaining insight into important and changeable determinants of schoolchildren’s fruit and vegetable intake. Part two describes the systematic development of an evidence-based and theory-driven intervention addressing relevant determinants of schoolchildren’s fruit and vegetable intake, i.e. taste preferences, knowledge of recommended intake levels, availability of fruit and vegetables, and parental influences. The intervention consisted of three components: educational lessons implemented at school, parental involvement and distribution of fruit and vegetables at school and has been implemented during two school years in the Netherlands, Norway and Spain. Part three of this thesis describes both the effect and process evaluation. Effects have been evaluated in a group-randomised trail among 2106 children from 62 schools. In each country schools were randomly assigned to an intervention or control group. The effects of this intervention on schoolchildren’s intake of fruit and vegetables, as well as changes in determinants of intake were assessed by means of validated questionnaires. Both at the short and the longer-term effects positive effects on frequency of fruit and vegetable intake, and portions of fruit intake were found. Besides, more children from the intervention group knew the daily-recommended intake levels for both fruit and vegetables. The short-term effects are associated with the degree of implementation of the lessons at school and degree of schoolchildren’s appreciation of the intervention

Unexpected Scaling of the Performance of Carbon Nanotube Transistors

We show that carbon nanotube transistors exhibit scaling that is qualitatively different than conventional transistors. The performance depends in an unexpected way on both the thickness and the dielectric constant of the gate oxide. Experimental measurements and theoretical calculations provide a consistent understanding of the scaling, which reflects the very different device physics of a Schottky barrier transistor with a quasi-one-dimensional channel contacting a sharp edge. A simple analytic model gives explicit scaling expressions for key device parameters such as subthreshold slope, turn-on voltage, and transconductance.Comment: 4 pages, 4 figure

Multi-sensor Cloud Retrieval Simulator and Remote Sensing from Model Parameters

In this paper we describe a general procedure for calculating synthetic sensor radiances from variable output from a global atmospheric forecast model. In order to take proper account of the discrepancies between model resolution and sensor footprint, the algorithm takes explicit account of the model subgrid variability, in particular its description of the probability density function of total water (vapor and cloud condensate.) The simulated sensor radiances are then substituted into an operational remote sensing algorithm processing chain to produce a variety of remote sensing products that would normally be produced from actual sensor output. This output can then be used for a wide variety of purposes such as model parameter verification, remote sensing algorithm validation, testing of new retrieval methods and future sensor studies.We show a specific implementation using the GEOS-5 model, the MODIS instrument and the MODIS Adaptive Processing System (MODAPS) Data Collection 5.1 operational remote sensing cloud algorithm processing chain (including the cloud mask, cloud top properties and cloud optical and microphysical properties products). We focus on clouds because they are very important to model development and improvement

Single-Walled Carbon Nanotubes as Shadow Masks for Nanogap Fabrication

We describe a technique for fabricating nanometer-scale gaps in Pt wires on insulating substrates, using individual single-walled carbon nanotubes as shadow masks during metal deposition. More than 80% of the devices display current-voltage dependencies characteristic of direct electron tunneling. Fits to the current-voltage data yield gap widths in the 0.8-2.3 nm range for these devices, dimensions that are well suited for single-molecule transport measurements

Engineering of Cyclodextrin Product Specificity and pH Optima of the Thermostable Cyclodextrin Glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1

The product specificity and pH optimum of the thermostable cyclodextrin glycosyltransferase (CGTase) from Thermoanaerobacterium thermosulfurigenes EM1 was engineered using a combination of x-ray crystallography and site-directed mutagenesis. Previously, a crystal soaking experiment with the Bacillus circulans strain 251 β-CGTase had revealed a maltononaose inhibitor bound to the enzyme in an extended conformation. An identical experiment with the CGTase from T. thermosulfurigenes EM1 resulted in a 2.6-Å resolution x-ray structure of a complex with a maltohexaose inhibitor, bound in a different conformation. We hypothesize that the new maltohexaose conformation is related to the enhanced α-cyclodextrin production of the CGTase. The detailed structural information subsequently allowed engineering of the cyclodextrin product specificity of the CGTase from T. thermosulfurigenes EM1 by site-directed mutagenesis. Mutation D371R was aimed at hindering the maltohexaose conformation and resulted in enhanced production of larger size cyclodextrins (β- and γ-CD). Mutation D197H was aimed at stabilization of the new maltohexaose conformation and resulted in increased production of α-CD. Glu258 is involved in catalysis in CGTases as well as α-amylases, and is the proton donor in the first step of the cyclization reaction. Amino acids close to Glu258 in the CGTase from T. thermosulfurigenes EM1 were changed. Phe284 was replaced by Lys and Asn327 by Asp. The mutants showed changes in both the high and low pH slopes of the optimum curve for cyclization and hydrolysis when compared with the wild-type enzyme. This suggests that the pH optimum curve of CGTase is determined only by residue Glu258.

Ab-initio theory of NMR chemical shifts in solids and liquids

We present a theory for the ab-initio computation of NMR chemical shifts (sigma) in condensed matter systems, using periodic boundary conditions. Our approach can be applied to periodic systems such as crystals, surfaces, or polymers and, with a super-cell technique, to non-periodic systems such as amorphous materials, liquids, or solids with defects. We have computed the hydrogen sigma for a set of free molecules, for an ionic crystal, LiH, and for a H-bonded crystal, HF, using density functional theory in the local density approximation. The results are in excellent agreement with experimental data.Comment: to appear in Physical Review Letter

Spin dynamics of the S=1/2 antiferromagnetic zig-zag ladder with anisotropy

We use exact diagonalization and the modified Lanczos method to study the finite energy and finite momentum spectral weight of the longitudinal and transverse spin excitations of the anisotropic zig-zag ladder. We find that the spin excitations form continua of gapless or gapped spinons in the different regions of the phase diagram. The results obtained are consistent with a picture previously proposed that in the anisotropic case there is a transition from a gapped regime to a gapless regime, for small interchain coupling. In this regime we find a sharp low-energy peak in the structure function for the transverse spin excitations, consistent with a finite stiffness.Comment: 17 figure

Equivalent Sensor Radiance Generation and Remote Sensing from Model Parameters

In this paper we describe a general procedure for calculating equivalent sensor radiances from variables output from a global atmospheric forecast model. In order to take proper account of the discrepancies between model resolution and sensor footprint the algorithm takes explicit account of the model subgrid variability, in particular its description of the probably density function of total water (vapor and cloud condensate.) The equivalent sensor radiances are then substituted into an operational remote sensing algorithm processing chain to produce a variety of remote sensing products that would normally be produced from actual sensor output. This output can then be used for a wide variety of purposes such as model parameter verification, remote sensing algorithm validation, testing of new retrieval methods and future sensor studies. We show a specific implementation using the GEOS-5 model, the MODIS instrument and the MODIS Adaptive Processing System (MODAPS) Data Collection 5.1 operational remote sensing cloud algorithm processing chain (including the cloud mask, cloud top properties and cloud optical and microphysical properties products.) We focus on clouds and cloud/aerosol interactions, because they are very important to model development and improvement