Surgically treated acute abdomen at Gondar University Hospital, Ethiopia.

Background: Acute abdomen is an acute onset of abdominal disease entities that require immediate surgical intervention in most of the cases. The numbers of researches done on acute abdomen in general are Very few in Ethiopia. The main objective of this study was to document the burden of acute abdomen in general and the outcome of emergency laparotomyMethods: This was a retrospective study on surgically treated acute abdomen performed at Gondar University Hospital (GUH) from September 1998 to August 2002Results: More than 1 in 10 operations done in GUH were for acute abdomen. Nearly a quarter of the operations performed in the study period were laparotomies, 43.3% of which were on emergency bases. Majority of surgically treated acute abdomen patients were from rural areas (58.2%). The sex composition was significantly different by place of residence (X2= 12.74, p=0.0017). Abdominal pain (100%), Vomiting (90.3%), abdominal distension (58.3%) and constipation (55.3%) were the commonest symptoms in patients with acute abdomen.Conclusion: This study has shown what the commonest symptoms of acute abdomen are and that the outcome of emergency laparotomy may be affected by different factors. Some of these factors were duration of illness, age, presence of peritonitis, Haematocrit level and complication detection time. Since the management is almost the same for almost all causes of surgical acute abdomens, the abovementioned factors should be given due attention in handling such patients. The reasons for low appearance of rural female dwellers to better health care centres need to be investigated

Determinants of calcified placenta and its association with fetal outcome among mothers who gave birth in Southern Ethiopia, 2018

Background: Placenta is a complex multifunctional organ that maintains pregnancy and promotes normal fetal development. Fetal outcome is adversely influenced by pathological changes in placenta because it is a mirror which reflects intrauterine status of fetus. Placental abnormalities are considered as leading cause of maternal and perinatal mortality. Objective of the study was to assess determinants of calcified placenta and its association with fetal outcomes.Methods: Institutional based unmatched case-control study was conducted on 213 placentas from mothers who gave birth at Dilla university referral hospital with an age range of 19-34 years. Calcifications were assessed radiologically and graded according to Grannum. Bivariate logistic regression analysis was identified and fitted to the multiple logistic regression analysis to identify the independent effects of each variable to the outcome variable. Chi-square test was used to find the potential association between grade two and above levels of calcification and fetal outcomes.Results: Total 213 singles parturient with their placenta above 37 weeks gestational age were included. The likelihood of developing grade two and above level of calcification associated with the following variables: educational status (OR=3.134; 95%CI: 1.208, 8.135),parity (OR 3.125; 95% CI: 1.354, 7.213) ,maternal anemia (OR 6.834;95%C: I2.626,17.803), smoking (OR 6.343;95% CI: 2.624,15.334),  abruption (OR 6.046;95% CI: 2.392,15.277), and pregnancy- induced hypertension (OR 4.868 ;95% CI: 2.095,11.354). In this study, neonatal outcomes in grade II and above level of calcification were poorer than grade I and bellow level of calcification in chi-square association test.Conclusions: Grade II and above level of placental calcification (case) was significantly associated with maternal pregnancy-induced pathologies, number of parity, maternal educational status, and results in different kind of anomalies, maternal and neonatal mortality. Therefore, the practice of placental examination before and after birth guarantees for feto-maternal wellbeing

Erratum: A large right ventricle and severe hypoxemia. Use of bedside transesophageal echocardiography to assess cardiopulmonary failure (Annals of the American Thoracic Society (2020) 17 (112-115) DOI: 10.1513/AnnalsATS.201904-316CC)

Copyright © 2020 by the American Thoracic Society. The authors would like to make a correction to the legends of Videos 1 and 3 in their article published in the January 2020 issue of AnnalsATS (1). The definition for the abbreviation TEE in these video legends should read transesophageal echocardiogram. For the convenience of our readers, AnnalsATS is replacing the online version of the article with a corrected version; we apologize for the error

Tyrosine phosphorylation controls brassinosteroid receptor activation by triggering membrane release of its kinase inhibitor

Receptor tyrosine kinases control many critical processes in metazoans, but these enzymes appear to be absent in plants. Recently, two Arabidopsis receptor kinases-BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1), the receptor and coreceptor for brassinosteroids-were shown to autophosphorylate on tyrosines. However, the cellular roles for tyrosine phosphorylation in plants remain poorly understood. Here, we report that the BRI1 KINASE INHIBITOR 1 (BKI1) is tyrosine phosphorylated in response to brassinosteroid perception. Phosphorylation occurs within a reiterated [KR][KR] membrane targeting motif, releasing BKI1 into the cytosol and enabling formation of an active signaling complex. Our work reveals that tyrosine phosphorylation is a conserved mechanism controlling protein localization in all higher organisms

Preparation and sorption property study of Fe3O4/Al2O3/ZrO2 composite for the removal of cadmium, lead and chromium ions from aqueous solutions

Fe-Al-Zr ternary mixed oxides composite was synthesized via co-precipitation method for the removal Pb(II), Cd(II) and Cr(VI) ions from aqueous solutions. The as-synthesized materials were characterized by X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), scanning electron microscope hyphenated with energy dispersive X-ray diffraction (SEM-EDX) and Fourier transform infrared (FTIR) techniques. The pH at the point of zero charge (pHpzc) of the sorbent and effect of ionic strength on sorption were also determined. The batch tests were conducted to optimize the various sorption parameters such as pH, adsorbent dose, contact time, speed of agitation and initial metal concentration. The experimental results showed that the adsorbed amounts of Pb(II), Cd(II) and Cr(VI) tend to decrease with increase in pH. Freundlich isotherm model fits better the equilibrium data for the adsorbent. Kinetic data correlated better with both pseudo first order and pseudo second order kinetic models. The spontaneous nature of the adsorption process was also confirmed from thermodynamic grounds. The nanosized adsorbent exhibited an adsorption efficiency of 96.65%, 96.55% and 97.2% for Cd(II), Cr(VI) and Pb(II), respectively, at optimum condition. Experimental results showed that the nanocomposite was effective for the removal of the title heavy metals from aqueous solution.   Bull. Chem. Soc. Ethiop. 2020, 34(1), 105-121. DOI: https://dx.doi.org/10.4314/bcse.v34i1.1

Precipitation Extremes in Dynamically Downscaled Climate Scenarios over the Greater Horn of Africa

This study first assesses the performance of regional climate models in the Coordinated Regional Climate Downscaling Experiment (CORDEX) in reproducing observed extreme precipitation indices over the Greater Horn of Africa (GHA) region during 1989–2005. The study then assesses projected changes in these extremes during 2069–2098 compared to 1976–2005. The Regional Climate Model (RCM) simulations are made using two RCMs, with large-scale forcing from four CMIP5 Global limate Models(GCMs) under two Representative Concentration Pathways (RCP4.5 and RCP8.5). We found that RCM simulations have reasonably captured observed patterns of moderate precipitation extreme indices (MPEI). Pattern correlation coefficients between simulated and observed MPEI exceed 0.5 for all except the Simple Daily Intensity Index (SDII). However, significant overestimations or underestimations exist over localized areas in the region. Projected changes in Total annual Precipitation (PRCPTOT) and the annual number of heavy (\u3e10 mm) and very heavy (\u3e20 mm) precipitation days by 2069–2098 show a general north-south pattern, with decreases over the southern half and increases over the northern half of the GHA. These changes are often greatest over parts of Somalia, Eritrea, the Ethiopian highlands and southern Tanzania. Maximum one- and five-day precipitation totals over a year and SDII (ratio of PRCPTOT to rainy days) are projected to increase over a majority of the GHA, including areas where PRCPTOT is projected to decrease, suggesting fewer, but heavier rainy days in the future. Changes in the annual sum of daily precipitation above the 95th and 99th percentiles are statistically significant over a few locations, with the largest projected decrease/increase over Eritrea and northwestern Sudan/Somalia. Projected changes in Consecutive Dry Days (CDD) suggest longer periods of dryness over the majority of the GHA, except the central portions covering northern Uganda, southern South Sudan, southeastern Ethiopia and Somalia. Substantial increases in CDD are located over southern Tanzania and the Ethiopian highlands. The magnitude and the spatial extent of statistically-significant changes in all MPEI increase from RCP4.5 to RCP8.5, and the separation between positive and negative changes becomes clearer under RCP8.5

Precipitation Extremes in Dynamically Downscaled Climate Scenarios over the Greater Horn of Africa

This study first assesses the performance of regional climate models in the Coordinated Regional Climate Downscaling Experiment (CORDEX) in reproducing observed extreme precipitation indices over the Greater Horn of Africa (GHA) region during 1989–2005. The study then assesses projected changes in these extremes during 2069–2098 compared to 1976–2005. The Regional Climate Model (RCM) simulations are made using two RCMs, with large-scale forcing from four CMIP5 Global limate Models(GCMs) under two Representative Concentration Pathways (RCP4.5 and RCP8.5). We found that RCM simulations have reasonably captured observed patterns of moderate precipitation extreme indices (MPEI). Pattern correlation coefficients between simulated and observed MPEI exceed 0.5 for all except the Simple Daily Intensity Index (SDII). However, significant overestimations or underestimations exist over localized areas in the region. Projected changes in Total annual Precipitation (PRCPTOT) and the annual number of heavy (\u3e10 mm) and very heavy (\u3e20 mm) precipitation days by 2069–2098 show a general north-south pattern, with decreases over the southern half and increases over the northern half of the GHA. These changes are often greatest over parts of Somalia, Eritrea, the Ethiopian highlands and southern Tanzania. Maximum one- and five-day precipitation totals over a year and SDII (ratio of PRCPTOT to rainy days) are projected to increase over a majority of the GHA, including areas where PRCPTOT is projected to decrease, suggesting fewer, but heavier rainy days in the future. Changes in the annual sum of daily precipitation above the 95th and 99th percentiles are statistically significant over a few locations, with the largest projected decrease/increase over Eritrea and northwestern Sudan/Somalia. Projected changes in Consecutive Dry Days (CDD) suggest longer periods of dryness over the majority of the GHA, except the central portions covering northern Uganda, southern South Sudan, southeastern Ethiopia and Somalia. Substantial increases in CDD are located over southern Tanzania and the Ethiopian highlands. The magnitude and the spatial extent of statistically-significant changes in all MPEI increase from RCP4.5 to RCP8.5, and the separation between positive and negative changes becomes clearer under RCP8.5

Small strain stiffness within logarithmic contractancy model for structured anisotropic clay.

ABSTRACT: Stiffness of soils in the small strain region is high and it decays nonlinearly with increasing shear strains or with mobilization of shear stresses. However, the commonly used critical state based constitutive models use a simple elastic formulation at small strains that falls short in the prediction of the small strain nonlinearity and anisotropy. This paper proposes a simple way for rendering the existing constitutive models with the capability to capture the small strain behaviour of soils. This is illustrated by proposing a new model for structured anisotropic clay extending an existing model that uses the framework of logarithmic contractancy called ESCLAY1S. The proposed model is implemented into a Finite Element program as a user-defined soil model. The model predictions are compared with experimental data for various clays. Furthermore, the effect of nonlinearity is investigated for an excavation in soft clay

Interaction-free measurement and forward scattering

Interaction-free measurement is shown to arise from the forward-scattered wave accompanying absorption: a "quantum silhouette" of the absorber. Accordingly, the process is not free of interaction. For a perfect absorber the forward-scattered wave is locked both in amplitude and in phase. For an imperfect one it has a nontrivial phase of dynamical origin (``colored silhouette"), measurable by interferometry. Other examples of quantum silhouettes, all controlled by unitarity, are briefly discussed.Comment: 4 pages in RevTex + 1 figure in eps; submitted to Phys. Rev. A since 09Jan98; now update