134 research outputs found

    Adaptive error control for finite element approximations of the lift and drag coefficients in viscous flow

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    We derive estimates for the error in a variational approximation of the lift and drag coefficients of a body immersed into a viscous flow governed by the Navier-Stokes equations. The variational approximation is based on computing a certain weighted average of a finite element approximation to the solution of the Navier-Stokes equations. Our main result is an a posteriori estimate that puts a bound on the error in the lift and drag coefficients in terms of the local mesh size, a local residual quantity, and a local weight describing the local stability properties of an associated dual problem. The weight may be approximated by solving the dual problem numerically. The error bound is thus computable and can be used for quantitative error estimation; we apply it to design an adaptive finite element algorithm specifically for the approximation of the lift and drag coefficients

    Stiff oscillatory systems, delta jumps and white noise

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    Two model problems for stiff oscillatory systems are introduced. Both comprise a linear superposition of N >> 1 harmonic oscillators used as a forcing term for a scalar ODE. In the first case the initial conditions are chosen so that the forcing term approximates a delta function as N tends to infinity, and in the second case so that it approximates white noise. In both cases the fastest natural frequency of the oscillators is O(N). The model problems are integrated numerically in the stiff regime where the time step is of size O(1/N). The convergence of the algorithms is studied in this case in the limit of N tending to infinity and the time step tending to zero. For the white noise problem both strong and weak convergence are considered

    Laboratory evaluation of hedmanite and lime modified asphalt concrete mixes

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    We prove the existence of large-data global-in-time weak solutions to an evolutionary PDE system describing flows of incompressible \emph{heat-conducting} viscoelastic rate-type fluids with stress-diffusion, subject to a stick-slip boundary condition for the velocity and a homogeneous Neumann boundary condition for the extra stress tensor. In the introductory section we develop the thermodynamic foundations of the proposed model, and we document the role of thermodynamics in obtaining critical structural relations between the quantities of interest. These structural relations are then exploited in the mathematical analysis of the governing equations. In particular, the definition of weak solution is motivated by the thermodynamic basis of the model. The extra stress tensor describing the elastic response of the fluid is in our case purely spherical, which is a simplification from the physical point of view. The model nevertheless exhibits features that require novel mathematical ideas in order to deal with the technically complex structure of the associated internal energy and the more complicated forms of the corresponding entropy and energy fluxes. The paper provides the first rigorous proof of the existence of large-data global-in-time weak solutions to the governing equations for \emph{coupled thermo-mechanical processes} in viscoelastic rate-type fluids

    Pengembangan TPA Sabilil Falaq melalui Penguatan SDM Pengajar di Gampong Janguet, Indra Jaya, Aceh Jaya

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    The quality of human resources is actually determined by the level of education. Quality and character education will certainly produce quality and character human beings. Al-Qur'an Education Park (TPA) is a place for non-formal education to study religious knowledge among children. The existence of the Qur'an education park is used as an effort to increase the knowledge of Islamic religious knowledge and character in children. Al-Quran education park has a major role to teach the ability to read and write the Koran. On this occasion, Serumpun Malay KKN students provided assistance and development at the Sabilil Falaq TPA related to strengthening the teaching staff of the Sabilil Falaq TPA. The method used is a qualitative method with data collection techniques, namely interview surveys, documentation, and field research. The results obtained are that there are several problems at TPA Sabilil Falaq, namely, the number of students is more than the number of teachers, the ability of teachers is still standard, and the lack of learning media in learning. The solution provided is to make efforts to add teaching teachers or to cadre students who are already capable, carry out training for Koran teachers, and provide fun and innovative learning media

    Strong and auxiliary forms of the semi-Lagrangian method for incompressible flows

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    We present a review of the semi-Lagrangian method for advection-diusion and incompressible Navier-Stokes equations discretized with high-order methods. In particular, we compare the strong form where the departure points are computed directly via backwards integration with the auxiliary form where an auxiliary advection equation is solved instead; the latter is also referred to as Operator Integration Factor Splitting (OIFS) scheme. For intermediate size of time steps the auxiliary form is preferrable but for large time steps only the strong form is stable

    Co-gasification of coal and empty fruit bunch in an entrained flow gasifier : A process simulation study

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    Co-gasification of coal and biomass is a proven method to improve gasification performance and a platform towards being independent of fossil fuel in power generation. Thus, this research was conducted to assess the feasibility of coal and EFB as fuels in co-gasification using Aspen HYSYS. A sequential model of an EFG was developed to predict the syngas composition and the optimum operating condition of the gasifier. The process was modelled with a set of five reactors to simulate various reaction zones of EFG in accordance with its hydrodynamics. The model considers devolatilization, char and volatile combustion, char gasification and water-gas shift reactions. The model prediction has exhibited excellent agreement with the experimental results. Three parameters of BR, Top and S/F were considered to account for their impacts on syngas composition in the process. The CE, CGE, PE and HHV were adopted as the indicators of process performance. The optimal values of BR, Top and S/F were 50%, 950°C and 0.75, respectively. While the value of CE reached above 90% and the maximum value of CGE, PE and HHV was obtained. This finding should be helpful in designing, operating, optimizing and controlling any co-gasification process especially in the entrained flow system

    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma

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    Despite the undisputable role of the small GTPase Rac1 in the regulation of actin cytoskeleton reorganization, the Rac guanine-nucleotide exchange factors (Rac-GEFs) involved in Rac1-mediated motility and invasion in human lung adenocarcinoma cells remain largely unknown. Here, we identify FARP1, ARHGEF39, and TIAM2 as essential Rac-GEFs responsible for Rac1-mediated lung cancer cell migration upon EGFR and c-Met activation. Noteworthily, these Rac-GEFs operate in a non-redundant manner by controlling distinctive aspects of ruffle dynamics formation. Mechanistic analysis reveals a leading role of the AXL-Gab1-PI3K axis in conferring pro-motility traits downstream of EGFR. Along with the positive association between the overexpression of Rac-GEFs and poor lung adenocarcinoma patient survival, we show that FARP1 and ARHGEF39 are upregulated in EpCam+ cells sorted from primary human lung adenocarcinomas. Overall, our study reveals fundamental insights into the complex intricacies underlying Rac-GEF-mediated cancer cell motility signaling, hence underscoring promising targets for metastatic lung cancer therapy.Fil: Cooke, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina. University of Pennsylvania; Estados UnidosFil: Kreider Letterman, Gabriel. University Of Toledo (utoledo); Estados UnidosFil: Baker, Martin James. University of Pennsylvania; Estados UnidosFil: Zhang, Suli. University of Pennsylvania; Estados UnidosFil: Sullivan, Neil T.. University of Pennsylvania; Estados UnidosFil: Eruslanov, Evgeniy. University of Pennsylvania; Estados UnidosFil: Abba, Martín Carlos. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Goicoechea, Silvia M.. University Of Toledo (utoledo); Estados UnidosFil: Garcia Mata, Rafael. University Of Toledo (utoledo); Estados UnidosFil: Kazanietz, Marcelo Gabriel. University of Pennsylvania; Estados Unido

    On the two-dimensional solution of both adhesive and non-adhesive contact problems involving functionally graded materials

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    This paper presents a semi-analytical algorithm for the determination of the contact half width and surface pressure which results from both adhesive and non-adhesive contact problems involving functionally graded materials (FGM). The inhomogeneously elastic solid comprises a graded elastic coating whose shear modulus depends exponentially on the vertical coordinate and a homogeneously elastic substrate. The solid is assumed to be in a state of plane strain and thus a two-dimensional analysis is performed within this work. Using the work of Chidlow et al. (2011a) as a starting point, we derive a pair of integral equations which may be used to determine approximations to the contact pressure when either the surface deflection or the deflection gradient is known over the contact region. As these integral equations are non-singular, we use Galerkin's method to approximate the contact pressure and it is found that relatively small trial spaces allow accurate computation of the pressure. Information about the prescribed load is then used to formulate an iterative algorithm to determine the contact half width. A selection of numerical results are presented using this method and it is found that the solutions computed here compare favourably with those of other authors. A further investigation is then conducted into the solution of adhesive contact problems using the assumptions of Maugis (1992) and Johnson and Greenwood (2008) to inform the nature of the adhesive stresses outside of the contact. It is found that both JKR-like and DMT-like behaviour can be observed in contact problems involving FGMs

    Sensitivity analysis of leaching process on rare earth elements by using metsim software

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    Leaching is part of the hydrometallurgical treatment in the separation of rare earth elements (REEs). The increase of demand for REEs in the world but its limited supply caused by the separation process that has negative environmental impact, as well as high costs of laboratory work, the alternative method to study on the extraction of these resources are urgently needed. This can be done through simulation study that eliminates the number of experiment that needs to be carried out. In this work, a sensitivity analysis of the leaching process for light rare earth elements (LREEs); Lanthanum (La) and Neodymium (Nd) from monazite concentrate was carried out by employing a software called METSIM which is able to model metallurgical processes. METSIM software is also able to calculate mass and heat balance of complicated hydrometallurgy processes and furthermore, its function has been expanded to involved chemical reactions, process control and equipment sizing. The simulation of the digestion and the leaching process was run and compared with experimental work from the literature, which aimed to optimize the leaching process. Leaching is an extraction process of a substance from a solid material that is dissolved in a liquid. In this study, the leaching process is modelled as a two-steps process, in which the first step is the digestion process, followed by the actual leaching process. The monazite concentrate is made strong bonds as REEs oxide, therefore, they are not soluble in water before leaching process. For the digestion process, the monazite concentrate was mixed with sulfuric acid (H2SO4) in the digestion reactor. The precipitates which contain leachate was then mixed with deionised water in the leaching reactor to increase the solubility of La and Nd. The reaction equations for the digestion reactor are as shown in Equations (1) and (2), while for the leaching reactor are shown by Equations (3) and (4) as follows

    Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo

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    Whether neurons can restore their original connectivity patterns during circuit repair is unclear. Taking advantage of the regenerative capacity of zebrafish retina, we show here the remarkable specificity by which surviving neurons reassemble their connectivity upon regeneration of their major input. H3 horizontal cells (HCs) normally avoid red and green cones, and prefer ultraviolet over blue cones. Upon ablation of the major (ultraviolet) input, H3 HCs do not immediately increase connectivity with other cone types. Instead, H3 dendrites retract and re-extend to contact new ultraviolet cones. But, if regeneration is delayed or absent, blue-cone synaptogenesis increases and ectopic synapses are made with red and green cones. Thus, cues directing synapse specificity can be maintained following input loss, but only within a limited time period. Further, we postulate that signals from the major input that shape the H3 HC's wiring pattern during development persist to restrict miswiring after damage
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