88 research outputs found

    Variabilite spatiale des rendements du riz en systeme de riziculture intensive (SRI) en zone office du Niger au Mali

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    Une étude exploratoire a été menée de 2009 à 2013 en vue d’évaluer la faisabilité technique du Système de Riziculture Intensive (SRI) dans cinq localités de l’Office du Niger. Le protocole expérimental comprenait 3 traitements : pratique paysanne avec la dose recommandée de fumure minérale (T1) ; méthode SRI avec 10 tonnes de fumier plus la dose d’engrais recommandée (T2) et méthode SRI avec 10 tonnes de fumier et la moitié de la dose vulgarisée de fumure minérale (T3). En plus, deux essais factoriels comprenant les combinaisons fumier X azote et phosphore X azote ont été conduits en station. Durant les 3 années d’étude, les rendements ont varié entre 4,5 et 10 t ha-1 et plus avec la méthode SRI et entre 3 et 8t ha-1 avec la méthode conventionnelle. En outre, une relation positive entre les pratiques de gestion des cultures et les rendements en milieu paysan a été observée. Il en a été de même pour les rendements et les facteurs sol notamment N et P. Dans près de 50 % des cas, la variabilité des rendements pouvait être expliquée par des pratiques culturales, et de gestion de la fertilité et de l’eau.Mots clés : Système de Riziculture Intensive, variabilité spatiale, facteur sol, fertilisation minérale, fumie

    Evaluating the impact of contour bunding technology on runoff, soil erosion and crop yield in southern Mali

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    United States Agency for International Developmen

    Responding to the changing WASH needs in Mali

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    The political unrest that started in Mali on the 21st of March 2012 has had a significant impact on access to safe water and sanitation for an estimated 1.9 million people. Like most development or non-humanitarian organisations, WaterAid Mali was forced to stop their water and sanitation interventions in northern target communities due to insecurity. In the south, water, sanitation and hygiene needs changed quickly, as a result of the large number of people migrating from the north. WaterAid Mali has adapted to these changes through reallocating resources, implementing new activities and internal capacity building. This paper will discuss the experiences of WaterAid Mali as well as the lessons learnt

    Prioritizing investments for climate-smart agriculture: Lessons learned from Mali

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    Agricultural productivity and growth in Mali are under threat from erratic rainfall, resulting in more frequent dry years. The national economy is vulnerable to climate change due to 50% of the gross domestic product coming from the agricultural sector and 75% of the population living in rural areas. The Climate-Smart Agriculture (CSA) concept arises from a need to provide innovative solutions towards the complex and integrated goals of increasing yields, improving resilience, and promoting a low emissions agricultural sector. A major challenge for policymakers to operationalize CSA is the identification, valuation (cost-benefit), and subsequent prioritization of climate-smart options and portfolios (groups of CSA options) for investment. This paper presents the process, results, and lessons learned from a yearlong pilot of the Climate-Smart Agriculture Prioritization Framework (CSA-PF) in Mali. Key national and international stakeholders participated in the co-development and prioritization of two CSA portfolios and related action plans for the Malian Sudanese zone. Initial steps towards outcomes of the process include inclusion of prioritized CSA practices in ongoing development projects and prompting discussion of modifications of future calls for agricultural development proposals by regional donors

    Understanding the evolution of immune genes in jawed vertebrates

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    Driven by co-evolution with pathogens, host immunity continuously adapts to optimize defence against pathogens within a given environment. Recent advances in genetics, genomics and transcriptomics have enabled a more detailed investigation into how immunogenetic variation shapes the diversity of immune responses seen across domestic and wild animal species. However, a deeper understanding of the diverse molecular mechanisms that shape immunity within and among species is still needed to gain insight into-and generate evolutionary hypotheses on-the ultimate drivers of immunological differences. Here, we discuss current advances in our understanding of molecular evolution underpinning jawed vertebrate immunity. First, we introduce the immunome concept, a framework for characterizing genes involved in immune defence from a comparative perspective, then we outline how immune genes of interest can be identified. Second, we focus on how different selection modes are observed acting across groups of immune genes and propose hypotheses to explain these differences. We then provide an overview of the approaches used so far to study the evolutionary heterogeneity of immune genes on macro and microevolutionary scales. Finally, we discuss some of the current evidence as to how specific pathogens affect the evolution of different groups of immune genes. This review results from the collective discussion on the current key challenges in evolutionary immunology conducted at the ESEB 2021 Online Satellite Symposium: Molecular evolution of the vertebrate immune system, from the lab to natural populations

    Discrepant Prevalence and Incidence of Leishmania Infection between Two Neighboring Villages in Central Mali Based on Leishmanin Skin Test Surveys

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    Leishmaniasis is a vector-borne disease transmitted to humans by the bite of an infected sand fly. Leishmaniasis is present in more than 88 countries and affects more than 12 million people. Depending on the species of Leishmania, the host can develop cutaneous leishmaniasis (CL), which is characterized by skin ulcers in uncovered parts of the body or a more severe form, visceral leishmaniasis, which affects the liver and spleen and is fatal if not treated. This study aims to establish the past and present infection with Leishmania parasites in two villages where recent cases have been diagnosed by the dermatology center (CNAM) in Bamako. This was achieved using a Leishmania-specific skin test that was administered annually to permanent residents of Kemena and Sougoula villages from 2006 to 2008. The results show that transmission of Leishmania is active and stable in these two villages. Moreover, despite sharing similar cultural and environmental features, the individuals from Kemena presented three times the risk of Leishmania infection compared with those from Sougoula. Our findings raise awareness of the continued presence of CL in Mali

    Seasonality and Prevalence of Leishmania major Infection in Phlebotomus duboscqi Neveu-Lemaire from Two Neighboring Villages in Central Mali

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    Phlebotomus duboscqi is the principle vector of Leishmania major, the causative agent of cutaneous leishmaniasis (CL), in West Africa and is the suspected vector in Mali. Although found throughout the country the seasonality and infection prevalence of P. duboscqi has not been established in Mali. We conducted a three year study in two neighboring villages, Kemena and Sougoula, in Central Mali, an area with a leishmanin skin test positivity of up to 45%. During the first year, we evaluated the overall diversity of sand flies. Of 18,595 flies collected, 12,952 (69%) belonged to 12 species of Sergentomyia and 5,643 (31%) to two species of the genus Phlebotomus, P. duboscqi and P. rodhaini. Of those, P. duboscqi was the most abundant, representing 99% of the collected Phlebotomus species. P. duboscqi was the primary sand fly collected inside dwellings, mostly by resting site collection. The seasonality and infection prevalence of P. duboscqi was monitored over two consecutive years. P. dubsocqi were collected throughout the year. Using a quasi-Poisson model we observed a significant annual (year 1 to year 2), seasonal (monthly) and village effect (Kemena versus Sougoula) on the number of collected P. duboscqi. The significant seasonal effect of the quasi-Poisson model reflects two seasonal collection peaks in May-July and October-November. The infection status of pooled P. duboscqi females was determined by PCR. The infection prevalence of pooled females, estimated using the maximum likelihood estimate of prevalence, was 2.7% in Kemena and Sougoula. Based on the PCR product size, L. major was identified as the only species found in flies from the two villages. This was confirmed by sequence alignment of a subset of PCR products from infected flies to known Leishmania species, incriminating P. duboscqi as the vector of CL in Mali

    Windborne long-distance migration of malaria mosquitoes in the Sahel

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    Over the past two decades efforts to control malaria have halved the number of cases globally, yet burdens remain high in much of Africa and the elimination of malaria has not been achieved even in areas where extreme reductions have been sustained, such as South Africa1,2. Studies seeking to understand the paradoxical persistence of malaria in areas in which surface water is absent for 3–8 months of the year have suggested that some species of Anopheles mosquito use long-distance migration3. Here we confirm this hypothesis through aerial sampling of mosquitoes at 40–290 m above ground level and provide—to our knowledge—the first evidence of windborne migration of African malaria vectors, and consequently of the pathogens that they transmit. Ten species, including the primary malaria vector Anopheles coluzzii, were identified among 235 anopheline mosquitoes that were captured during 617 nocturnal aerial collections in the Sahel of Mali. Notably, females accounted for more than 80% of all of the mosquitoes that we collected. Of these, 90% had taken a blood meal before their migration, which implies that pathogens are probably transported over long distances by migrating females. The likelihood of capturing Anopheles species increased with altitude (the height of the sampling panel above ground level) and during the wet seasons, but variation between years and localities was minimal. Simulated trajectories of mosquito flights indicated that there would be mean nightly displacements of up to 300 km for 9-h flight durations. Annually, the estimated numbers of mosquitoes at altitude that cross a 100-km line perpendicular to the prevailing wind direction included 81,000 Anopheles gambiae sensu stricto, 6 million A. coluzzii and 44 million Anopheles squamosus. These results provide compelling evidence that millions of malaria vectors that have previously fed on blood frequently migrate over hundreds of kilometres, and thus almost certainly spread malaria over these distances. The successful elimination of malaria may therefore depend on whether the sources of migrant vectors can be identified and controlled
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