2,566 research outputs found
Utilization of Media-Driven Technology for Health Promotion and Risk Reduction among American Indian and Alaska Native Young Adults: An Exploratory Study
Across the developmental spectrum, American Indian and Alaska Native (AI/AN) adolescents and young adults experience considerable behavioral and mental health disparities, including substance abuse, depression, and engagement in sexual behaviors which enhance risk of pregnancy and sexually transmitted infections. Health-focused interventions utilizing digital and media technology hold significant promise among tribal communities, as they have the capacity to eliminate geography-based barriers. Utilizing a sample of 210 self-identified AI/AN students attending tribal colleges, this study identified the most effective technologies and intervention strategies, as well as health seeking patterns and preferences, which may impact implementation and sustainable use in tribal settings. The use of technology was both diverse and pervasive among AI/AN young adults, mirroring or exceeding patterns of young adults from the broader population. These data suggest that technology-based interventions may effectively deliver information, resources, and behavior change tools to AI/AN young adults, particularly when reflecting their unique worldviews and social contexts
Deconstructing the Model Minority Myth: Exploring Health Risk Behaviors of American Asian and Pacific Islander Young Adults
The model minority stereotype describes Asian and Pacific Islanders (API) as the epitome of assimilation into U.S. culture using hard work, intelligence, high educational attainment, and economic success to overcome the challenges of discrimination and recent immigration. Adopted model minority pressures assume a life of their own, with origins in childhood that are amplified during adolescence and young adulthood. In response to evidence of increased vulnerability to HIV and other sexually transmitted infection exposure, the present study compared prevalence estimates of health risk behaviors of API and cross-ethnic college students (N = 1,880). Self-reported alcohol use and abuse tendencies, legal and illicit drug use, abuse and misuse, as well as HIV- and other STI-related sexual risk were compared. Results of independent samples t-tests revealed that API displayed greater risk for alcohol use, abuse, dependence, and negative outcomes related to use. After controlling for differences in the 90-day prevalence of sexual activity, Cochran-Mantel-Haenszel and chi-square analyses indicated significantly greater behavioral risks for infection among API. API males were nearly twice as likely as their cross-ethnic peers to engage in insertive oral and anal sex without a condom to the point of ejaculation. While reporting fewer risks compared to their male counterparts, API females were significantly more likely than their cross-ethnic peers to engage in behaviors which may enhance exposure to infection. Such findings suggest a shrinking cultural divide with regard to risk behaviors on college campuses, as well as a lack of perceived HIV and other sexually transmitted infection risk among API students. As universities continue to foster cultures of diversity, the unique experiences and prevention-based needs of API students must be addressed
Long-term efficacy of OROS® hydromorphone combined with pregabalin for chronic non-cancer neuropathic pain.
BACKGROUND AND OBJECTIVES:
Treatment for chronic non-cancer neuropathic pain can be complicated by side effects and drug interactions. Combining opioid analgesics and calcium channel modulators may overcome these and improve efficacy. The objective of the present study was to evaluate the efficacy and safety of OROS® hydromorphone combined with pregabalin in patients with chronic non-cancer neuropathic pain.
METHODS:
This retrospective observational study was conducted on clinical records from patients aged ≥18 years with chronic non-cancer neuropathic [>4 on the Douleur Neuropathique en 4 questions (DN4) scale] pain of ≥6 months duration, with severe intensity [>4 on the Numerical Rating Scale (NRS); range 0-10], who attended all visits and had ≥12 months of follow-up at the Tor Vergata University Polyclinic Hospital, from November 2008 to February 2011. Patients received an oral combination of OROS® hydromorphone and pregabalin. Pain was evaluated at each visit (months 1, 3, 6, 9, and 12) using the NRS and DN4 scale; Patients' Global Impression of Change (PGIC) was administered at months 1, 6, and 12. Dosage and side effects were recorded at each visit.
RESULTS:
Of 1,292 patients (32 % men, mean ± SD age 67.6 ± 11.9 years), 1,126 attended all visits. Seventeen percent (n = 224) had purely neuropathic pain. Initial mean dosage was 6.06 ± 2.00 mg/day for OROS® hydromorphone, 113.02 ± 21.94 mg/day for pregabalin. Dosages increased up to month 6, and returned to near initial dosages at month 12 (range 4-120 mg/day for OROS® hydromorphone; 75-600 mg/day for pregabalin). NRS pain scores (mean ± standard deviation) were 7.25 ± 1.34 at baseline and 1.85 ± 1.36 at 12 months (p < 0.0001); DN4 scores were 6.19 ± 1.65 at baseline, reduced to 1.84 ± 1.25 at 12 months (p < 0.0001), reductions of 74.4 and 70.2 %, respectively. More than 90 % of patients had a ≥50 % score reduction on both scales after 12 months. The PGIC scale showed that >75 % of patients felt improvement at 1 month, increasing to 91 % and 93 % at 6 and 12 months. The incidence of side effects was similar between elderly (aged >65 years) and younger subjects; there were no cases of addiction.
CONCLUSIONS:
The OROS® hydromorphone and pregabalin combination was efficacious for chronic non-cancer neuropathic pain and well tolerated, providing significant pain reduction without the risk of addiction and with a good tolerability profile, regardless of age
Exploring Sexual and Behavioral Health Inequities among College Students: A Need for LGB-Specific Risk Reduction
Many studies have examined differences in sexual behavior based upon self-identified sexual orientation, with results often indicating that those with same-sex partners engage in greater risk behaviors than those with opposite sex partners. However, few of those studies consisted of large, national sample studies. To address that gap, the present study examined the relationship between sexual orientation and both behavioral and sexual health outcomes in a national sample of U.S. college students. The Fall 2012 through Spring 2014 American College Health Association National College Health Assessment was used to examine behavioral and sexual health related responses from self-identified heterosexual, gay, lesbian, and bisexual students (N = 152,050). Items related to depression, abusive relationships, suicidal ideation, substance use, and engagement in consensual and nonconsensual sexual behaviors were examined. A series of cross tabulations indicated that sexual orientation was significantly associated with antecedents to sexual risk, including diagnoses of depression and engagement in abusive relationships. Self-identified sexual minorities reported significantly greater suicidal ideation and attempts, as well as engage in greater quantities of cigarette, alcohol, and marijuana use. Not only was sexual orientation significantly associated with the number of sexual partners in the previous 12 months, but similarly the occurrence of unprotected sex, sexual behaviors without providing consent, and sexual behaviors without receiving consent. Such findings were consistently found when disaggregating by sexual orientation and gender, and suggest that, as universities continue to foster a culture of diversity and acceptance, the unique experiences and prevention-based needs of sexual minority students must be addressed
Kinetics of growth of non-equilibrium fluctuations during thermodiffusion in a polymer solution
Abstract.: A thermal diffusion process occurring in a binary liquid mixture is accompanied by long ranged non-equilibrium concentration fluctuations. The amplitude of these fluctuations at large length scales can be orders of magnitude larger than that of equilibrium ones. So far non-equilibrium fluctuations have been mainly investigated under stationary or quasi-stationary conditions, a situation that allows to achieve a detailed statistical characterization of their static and dynamic properties. In this work we investigate the kinetics of growth of non-equilibrium concentration fluctuations during a transient thermodiffusion process, starting from a configuration where the concentration of the sample is uniform. The use of a large molecular weight polymer solution allows to attain a slow dynamics of growth of the macroscopic concentration profile. We focus on the development of fluctuations at small wave vectors, where their amplitude is strongly limited by the presence of gravity. We show that the growth rate of non-equilibrium fluctuations follows a power law Rf(q,t) 1d1t as a function of time, without any typical time scale and independently of the wave vector. We formulate a phenomenological model that allows to relate the rate of growth of non-equilibrium fluctuations to the growth of the macroscopic concentration profile in the absence of arbitrary parameters
Enfezamentos: doenças do milho disseminadas por inseto.
bitstream/item/35602/1/Enfezamentos-doencas.pd
Effect of electric load and dual atmosphere on the properties of an alkali containing diopside-based glass sealant for solid oxide cells
© 2019 Elsevier B.V. All rights reserved.A new alkali-containing diopside based glass-ceramic sealant for solid oxide cells was synthesized, characterized and tested. The composition was designed to match the coefficient of thermal expansion (CTE) of Crofer22APU interconnect. The sealant has a glass transition temperature of 600°C, a crystallization peak temperature of 850°C and a maximum shrinkage temperature of 700°C, thus suggesting effective densification prior to crystallization. The CTE of the glass-ceramic is 11.5 10-6 K-1, a value which is compatible with the CTE for Crofer22APU stainless steel. Crofer22APU/glass-ceramic/Crofer22APU joined samples were tested in simulated real-life operating conditions at 800°C in dual atmosphere under an applied voltage, monitoring the electrical resistivity. The effect of two different applied voltages (0.7V and 1.3V) was evaluated. A voltage of 1.3V led to a rapid decrease in the electrical resistivity during the test;such a drop was due to the formation of Cr2O3 “bridges” that connected the two Crofer22APU plates separated by the sealant. There was no decrease in the resistivity when a voltage of 0.7V was applied. Instead,resistivity value remained stable at around 105 Ω cm for the 100h test duration. The degradation mechanisms, due to both the alkali content and the applied voltage, are investigated and discussed.Peer reviewe
Effect of the corn stunt spiroplasma disease on maize production.
Suplemento. Edição dos Abstracts do 10º International Congress of Plant Pathology, Beijing, 2013
Plio-Pleistocene stratigraphic and tectonic evolution of the foreland-foredeep-chain system in Southern Italy
IncidĂŞncia do inseto-vetor de molicutes e de enfezamentos em milho.
xTrabalho apresentado no 31Âş Congresso Paulista de Fitopatologia, 2008, Campinas
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