Roles de género y sexismo en la publicidad de las revistas españolas: un análisis de las tres últimas décadas del siglo XX

En el presente trabajo se efectúa un análisis de contenido de la publicidad española en el medio revistas durante las últimas tres décadas del siglo XX. El objetivo último es el estudio de la evolución del contenido latente y manifiesto de la misma con relación a los estereotipos femenino y masculino. En este sentido, se procede en primer lugar a un análisis de la literatura concerniente a diversos estudios de naturaleza longitudinal realizados con relación al contenido de la publicidad impresa. A continuación se plantea un estudio empírico, mediante el uso del análisis de contenido, para abordar la evolución de la publicidad impresa española. Para ello se selecciona como período de análisis los años 1975, 1985, 1995 y 1999 y como fuente las revistas de periodicidad semanal y mensual dirigidas a hombres, a mujeres y de carácter general. Por último, se presentan los resultados y conclusiones del estudio, donde queda puesto de manifiesto los cambios producidos en la publicidad impresa española analizada

BCL3-rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases

The t(14;19)(q32;q13) often juxtaposes BCL3 with IGH resulting in overexpression of the gene. In contrast to other oncogenic translocations, BCL3-rearrangement (BCL3-R) has been associated with a broad spectrum of lymphoid neoplasms. Here we report an integrative whole-genome sequence, transcriptomic, and DNA methylation analysis of 13 lymphoid neoplasms with BCL3-R. The resolution of the breakpoints at single base-pair revealed that they occur in two clusters at 5' (n=9) and 3' (n=4) regions of BCL3 associated with two different biological and clinical entities. Both breakpoints were mediated by aberrant class switch recombination of the IGH locus. However, the 5' breakpoints (upstream) juxtaposed BCL3 next to an IGH enhancer leading to overexpression of the gene whereas the 3' breakpoints (downstream) positioned BCL3 outside the influence of the IGH and were not associated with its expression. Upstream BCL3-R tumors had unmutated IGHV, trisomy 12, and mutated genes frequently seen in CLL but had an atypical CLL morphology, immunophenotype, DNA methylome, and expression profile that differ from conventional CLL. In contrast, downstream BCL3-R neoplasms were atypical splenic or nodal marginal zone lymphomas (MZL) with mutated IGHV, complex karyotypes and mutated genes typical of MZL. Two of the latter 4 tumors transformed to a large B-cell lymphoma. We designed a novel FISH assay that recognizes the two different breakpoints and validated these findings in 17 independent tumors. Overall, upstream or downstream breakpoints of BCL3-R are mainly associated with two subtypes of lymphoid neoplasms with different (epi)genomic, expression, and clinicopathological features resembling atypical CLL and MZL, respectively

BCL3-rearrangements in B-cell lymphoid neoplasms occur in two breakpoint clusters associated with different diseases

The t(14;19)(q32;q13) often juxtaposes BCL3 with immunoglobulin heavy chain (IGH) resulting in overexpression of the gene. In contrast to other oncogenic translocations, BCL3 rearrangement (BCL3-R) has been associated with a broad spectrum of lymphoid neoplasms. Here we report an integrative whole-genome sequence, transcriptomic, and DNA methylation analysis of 13 lymphoid neoplasms with BCL3-R. The resolution of the breakpoints at single base-pair revealed that they occur in two clusters at 5' (n=9) and 3' (n=4) regions of BCL3 associated with two different biological and clinical entities. Both breakpoints were mediated by aberrant class switch recombination of the IGH locus. However, the 5' breakpoints (upstream) juxtaposed BCL3 next to an IGH enhancer leading to overexpression of the gene whereas the 3' breakpoints (downstream) positioned BCL3 outside the influence of the IGH and were not associated with its expression. Upstream BCL3-R tumors had unmutated IGHV, trisomy 12, and mutated genes frequently seen in chronic lymphocytic leukemia (CLL) but had an atypical CLL morphology, immunophenotype, DNA methylome, and expression profile that differ from conventional CLL. In contrast, downstream BCL3-R neoplasms were atypical splenic or nodal marginal zone lymphomas (MZL) with mutated IGHV, complex karyotypes and mutated genes typical of MZL. Two of the latter four tumors transformed to a large B-cell lymphoma. We designed a novel fluorescence in situ hybridization assay that recognizes the two different breakpoints and validated these findings in 17 independent tumors. Overall, upstream or downstream breakpoints of BCL3-R are mainly associated with two subtypes of lymphoid neoplasms with different (epi)genomic, expression, and clinicopathological features resembling atypical CLL and MZL, respectively

Cultural perspectives: Chinese perceptions of UK hotel service quality

Purpose – The purpose of this paper is to assess Chinese tourists' perceptions of the UK hotel service quality, and to analyze the role of Chinese culture in influencing their expectations and perceptions. Design/methodology/approach – An adapted SERVQUAL questionnaire for measuring hotel service quality attributes, and paired t-test and the Mann-Whitney test for data analysis were used in the study. Findings – The main findings fully support the hypotheses developed, and reveal a number of shortfalls, particularly on the empathy, reliability and tangible dimensions, in UK hotel services, which have led to negative consumers' experiences. Research limitations/implications – Future study requires a larger sample size with more sophisticated statistical analysis, and also additional emphasis on the price/value relationship for hotels themselves, and the hotel category. Practical implications – These are implications for the UK hotel marketers, managers, and employees, who may use the findings to adapt services to capitalize on the potential of Chinese outbound travel to the UK. Originality/value – This exploratory study provides fresh insights on the interrelationships of cultural influences and customers' evaluations of service quality

Location, market orientation, and firm performance: An analysis of the Colombian healthcare industry

In the Latin American healthcare industry, there seems to be an association between the implementation of the marketing strategies and the firms' location that suggests the need to study the organizational performance under these aspects. To this end, this paper contrasts the relationships between an organization's market orientation (MO), its location (for example, within a service cluster), and performance. The quantitative analysis was carried out among managers' perceptions from 134 service companies belonging to the healthcare service companies operating in the city of Cali, Colombia. The results showed a positive association between being located in a service cluster and business performance. It was also shown that the strategic approach based on OM positively affects performance. Moreover, we noted that competitors' orientation is the only component of the OM construct that significantly influences performance. The conclusions of our study allow for guiding the strategic decisionmaking of the managers of these companies regarding the decisions of location and content of marketing strategies

Crop rotations with Mi gene resistant and susceptible tomato cultivars for management of root-knot nematodes in plastic houses

Postprint (published version

Crop rotations with Mi gene resistant and susceptible tomato cultivars for management of root-knot nematodes in plastic houses

Postprint (published version