Magnetic diffusivity tensor and dynamo effects in rotating and shearing turbulence

The turbulent magnetic diffusivity tensor is determined in the presence of rotation or shear. The question is addressed whether dynamo action from the shear-current effect can explain large-scale magnetic field generation found in simulations with shear. For this purpose a set of evolution equations for the response to imposed test fields is solved with turbulent and mean motions calculated from the momentum and continuity equations. The corresponding results for the electromotive force are used to calculate turbulent transport coefficients. The diagonal components of the turbulent magnetic diffusivity tensor are found to be very close together, but their values increase slightly with increasing shear and decrease with increasing rotation rate. In the presence of shear, the sign of the two off-diagonal components of the turbulent magnetic diffusion tensor is the same and opposite to the sign of the shear. This implies that dynamo action from the shear--current effect is impossible, except perhaps for high magnetic Reynolds numbers. However, even though there is no alpha effect on the average, the components of the alpha tensor display Gaussian fluctuations around zero. These fluctuations are strong enough to drive an incoherent alpha--shear dynamo. The incoherent shear--current effect, on the other hand, is found to be subdominant.Comment: 12 pages, 13 figures, improved version, accepted by Ap

Protective Factors of Low Bone Mineral Density: An Examination between Two Samples of Premenopausal Women

While minimal longitudinal data exists to support osteoporosis screening among premenopausal women, an increasingly modernized society may contribute to modifiable osteoporosis risk factors including poor nutrition and low physical activity. Evaluation of bone mineral density (BMD) and body composition differences in populations with varied levels of physical activity is of importance. PURPOSE: The purpose of the current research was to determine if there is a difference across body composition measurements including total lean mass, body mass index (BMI), and BMD among a subset of physically active premenopausal women (ACTIVE) at a small, southern Christian university compared to premenopausal women from the general U.S. population in the National Health and Nutrition Examination Survey (NHANES). METHODS: BMD z-scores were calculated for premenopausal females who underwent a Dual-Energy X-Ray Absorptiometry (DXA) scan in a university performance lab from 2009 to 2023, matched to age, sex, and race/ethnicity participants from NHANES. Participants were classified by low or normal BMD using the International Society for Clinical Densitometry recommended cutoff of -2.0 for total body and by BMI using standard weight status categories published by the Centers for Disease Control and Prevention. Descriptive statistics were used to analyze participant characteristics and percentage across BMI and BMD categories. Total lean mass was reported by mean and standard deviation for ACTIVE and NHANES participants across BMI and BMD categories. Independent t-tests were used to determine if any differences existed between the ACTIVE and NHANES participants across total lean mass, BMI, and BMD. RESULTS: Data analysis included 2037 from the ACTIVE sample and 4326 from the NHANES sample. The frequency of low BMD (\u3c-2.0) among ACTIVE participants is 0.39% (n = 8) compared to 3.7% (n = 78) among NHANES participants. ACTIVE participants had significantly higher BMD [t(3361.21) = 26.49, p \u3c 0.001] and a significantly greater total lean mass [t(4677.71) = 11.14, p \u3c 0.01) than NHANES participants. Intriguingly, ACTIVE participants had a higher mean total lean mass than NHANES participants across all BMI categories except those classified as obese, regardless of BMD. CONCLUSION: The ACTIVE sample demonstrated a decreased prevalence of low BMD, likely attributed to increased physical activity. These observed differences in BMD are supported by higher total lean mass and lower rates of obesity likely also attributed to their physical activity history. This data supports the importance of lifestyle habits and its beneficial effects on both BMD and indices of body composition among premenopausal women

Waves, Coriolis force and the dynamo effect

Dynamo activity caused by waves in a rotating magneto-plasma is investigated. In astrophysical environments such as accretion disks and at sufficiently small spatial scales, the Hall effect is likely to play an important role. It is shown that a combination of the Coriolis force and Hall effect can produce a finite $\alpha$-effect by generating net helicity in the small scales. The shear/ion-cyclotron normal mode of the Hall plasma is the dominant contributor to the dynamo action for short scale motions.Comment: 8 pages, 3 figures, ApJ (in press

Multiscale characterization of chemical-mechanical interactions between polymer fibers and cementitious matrix

Together with a series of mechanical tests, the interactions and potential bonding between polymeric fibers and cementitious materials were studied using scanning transmission X-ray microscopy (STXM) and microtomography (mu CT). Experimental results.showed that these techniques have great potential to characterize the polymer fiber-hydrated cement-paste matrix interface, as well as differentiating the chemistry of the two components of a bi-polymer (hybrid) fiber-the polypropylene core and the ethylene acrylic acid copolymer sheath. Similarly, chemical interactions between the hybrid fiber and the cement hydration products were observed, indicating the chemical bonding between the sheath and the hardened cement paste matrix. Microtomography allowed visualization of the performance of the samples, and the distribution and orientation of the two types of fiber in mortar. Beam flexure tests confirmed improved tensile strength of mixes containing hybrid fibers, and expansion bar tests showed similar reductions in expansion for the polypropylene and hybrid fiber mortar bars

Blockade of T-cell activation by dithiocarbamates involves novel mechanisms of inhibition of nuclear factor of activated T cells.

Dithiocarbamates (DTCs) have recently been reported as powerful inhibitors of NF-kappaB activation in a number of cell types. Given the role of this transcription factor in the regulation of gene expression in the inflammatory response, NF-kappaB inhibitors have been suggested as potential therapeutic drugs for inflammatory diseases. We show here that DTCs inhibited both interleukin 2 (IL-2) synthesis and membrane expression of antigens which are induced during T-cell activation. This inhibition, which occurred with a parallel activation of c-Jun transactivating functions and expression, was reflected by transfection experiments at the IL-2 promoter level, and involved not only the inhibition of NF-kappaB-driven reporter activation but also that of nuclear factor of activated T cells (NFAT). Accordingly, electrophoretic mobility shift assays (EMSAs) indicated that pyrrolidine DTC (PDTC) prevented NF-kappaB, and NFAT DNA-binding activity in T cells stimulated with either phorbol myristate acetate plus ionophore or antibodies against the CD3-T-cell receptor complex and simultaneously activated the binding of AP-1. Furthermore, PDTC differentially targeted both NFATp and NFATc family members, inhibiting the transactivation functions of NFATp and mRNA induction of NFATc. Strikingly, Western blotting and immunocytochemical experiments indicated that PDTC promoted a transient and rapid shuttling of NFATp and NFATc, leading to their accelerated export from the nucleus of activated T cells. We propose that the activation of an NFAT kinase by PDTC could be responsible for the rapid shuttling of the NFAT, therefore transiently converting the sustained transactivation of this transcription factor that occurs during lymphocyte activation, and show that c-Jun NH2-terminal kinase (JNK) can act by directly phosphorylating NFATp. In addition, the combined inhibitory effects on NFAT and NF-KB support a potential use of DTCs as immunosuppressants

Dynamical evolution of neutrino--cooled accretion disks: detailed microphysics, lepton-driven convection, and global energetics

We present a detailed, two dimensional numerical study of the microphysical conditions and dynamical evolution of accretion disks around black holes when neutrino emission is the main source of cooling. Such structures are likely to form after the gravitational collapse of massive rotating stellar cores, or the coalescence of two compact objects in a binary (e.g., the Hulse--Taylor system). The physical composition is determined self consistently by considering two regimes: neutrino--opaque and neutrino--transparent, with a detailed equation of state which takes into account neutronization, nuclear statistical equilibrium of a gas of free nucleons and alpha particles, blackbody radiation and a relativistic Fermi gas of arbitrary degeneracy. Various neutrino emission processes are considered, with electron/positron capture onto free nucleons providing the dominant contribution to the cooling rate. We find that important temporal and spatial scales, related to the optically thin/optically thick transition are present in the disk, and manifest themselves clearly in the energy output in neutrinos. This transition produces an inversion of the lepton gradient in the innermost regions of the flow which drives convective motions, and affects the density and disk scale height radial profiles. The electron fraction remains low in the region close to the black hole, and if preserved in an outflow, could give rise to heavy element nucleosynthesis. Our specific initial conditions arise from the binary merger context, and so we explore the implications of our results for the production of gamma ray bursts.Comment: 26 pages, 12 figures, to appear in Ap

On the rotational evolution of solar- and late-type stars, its magnetic origins, and the possibility of stellar gyrochronology

We propose a simple interpretation of the rotation period data for solar- and late-type stars. The open cluster and Mt. Wilson star observations suggest that rotating stars lie primarily on two sequences, initially called I and C. Some stars lie in the intervening gap. These sequences, and the fractional numbers of stars on each sequence evolve systematically with cluster age, enabling us to construct crude rotational isochrones allowing `stellar gyrochronology', a procedure, upon improvement, likely to yield ages for individual field stars. The age and color dependences of the sequences allow the identification of the underlying mechanism, which appears to be primarily magnetic. The majority of solar- and late-type stars possess a dominant Sun-like, or Interface magnetic field, which connects the convective envelope both to the radiative interior of the star and to the exterior where winds can drain off angular momentum. These stars spin down Skumanich-style. An age-decreasing fraction of young G, K, and M stars, which are rapid rotators, possess only a Convective field which is not only inefficient in depleting angular momentum, but also incapable of coupling the surface convection zone to the inner radiative zone, so that only the outer zone is spun down, and on an exponential timescale. These stars do not yet possess large-scale dynamos. The large-scale magnetic field associated with the dynamo, apparently created by the shear between the decoupled radiative and convective zones, (re)couples the convective and radiative zones and drives a star from the Convective to the Interface sequence through the gap on a timescale that increases as stellar mass decreases. (Abstract is truncated here.)Comment: 32 pages, 6 figures (4 in color), accepted by Ap

Interference of flavonoids with enzymatic assays for the determination of free fatty acid and triglyceride levels

Flavonoids are bioactive food compounds with potential lipid-lowering effects. Commercially available enzymatic assays are widely used to determine free fatty acid (FFA) and triglyceride (TG) levels both in vivo in plasma or serum and in vitro in cell culture medium or cell lysate. However, we have observed that various flavonoids interfere with peroxidases used in these enzymatic assays, resulting in incorrect lower FFA and TG levels than actually present. Furthermore, addition of isorhamnetin or the major metabolite of the flavonoid quercetin in human and rat plasma, quercetin-3-O-glucuronide, to murine serum also resulted in a significant reduction of the detected TG levels, while a trend was seen for FFA levels. It is concluded that when applying these assays, vigilance is needed and alternative analytical methods, directly assessing FFA or TG levels, should be used for studying the biological effects of flavonoids on FFA and TG levels