143 research outputs found
Decentralised control for complex systems - An invited survey
© 2014 Inderscience Enterprises Ltd. With the advancement of science and technology, practical systems are becoming more complex. Decentralised control has been recognised as a practical, feasible and powerful tool for application to large scale interconnected systems. In this paper, past and recent results relating to decentralised control of complex large scale interconnected systems are reviewed. Decentralised control based on modern control approaches such as variable structure techniques, adaptive control and backstepping approaches are discussed. It is well known that system structure can be employed to reduce conservatism in the control design and decentralised control for interconnected systems with similar and symmetric structure is explored. Decentralised control of singular large scale systems is also reviewed in this paper
Edaphic factors and plants influence denitrification in soils from a long-term arable experiment
Factors influencing production of greenhouse gases nitrous oxide (N2O) and nitrogen (N2) in arable soils include high nitrate, moisture and plants; we investigate how differences in the soil microbiome due to antecedent soil treatment additionally influence denitrification. Microbial communities, denitrification gene abundance and gas production in soils from tilled arable plots with contrasting fertilizer inputs (no N, mineral N, FYM) and regenerated woodland in the long-term Broadbalk field experiment were investigated. Soil was transferred to pots, kept bare or planted with wheat and after 6 weeks, transferred to sealed chambers with or without K15NO3 fertilizer for 4 days; N2O and N2 were measured daily. Concentrations of N2O were higher when fertilizer was added, lower in the presence of plants, whilst N2 increased over time and with plants. Prior soil treatment but not exposure to N-fertiliser or plants during the experiment influenced denitrification gene (nirK, nirS, nosZI, nosZII) relative abundance. Under our experimental conditions, denitrification generated mostly N2; N2O was around 2% of total gaseous N2?+?N2O. Prior long-term soil management influenced the soil microbiome and abundance of denitrification genes. The production of N2O was driven by nitrate availability and N2 generation increased in the presence of plants
The Most Obscured AGNs in the XMM-SERVS Fields
We perform X-ray spectral analyses to derive the characteristics (e.g., column density, X-ray luminosity) of ≈10,200 active galactic nuclei (AGNs) in the XMM-Spitzer Extragalactic Representative Volume Survey, which was designed to investigate the growth of supermassive black holes across a wide dynamic range of cosmic environments. Using physical torus models (e.g., Borus02) and a Bayesian approach, we uncover 22 representative Compton-thick (CT; NH > 1.5 × 1024 cm−2) AGN candidates with good signal-to-noise ratios as well as a large sample of 136 heavily obscured AGNs. We also find an increasing CT fraction (fCT) from low (z 0.75) redshift. Our CT candidates tend to show hard X-ray spectral shapes and dust extinction in their spectral energy distribution fits, which may shed light on the connection between AGN obscuration and host-galaxy evolution
The Most Obscured AGNs in the XMM-SERVS Fields
We perform X-ray spectral analyses to derive characteristics (e.g., column
density, X-ray luminosity) of 10,200 active galactic nuclei (AGNs) in
the XMM-Spitzer Extragalactic Representative Volume Survey (XMM-SERVS), which
was designed to investigate the growth of supermassive black holes across a
wide dynamic range of cosmic environments. Using physical torus models (e.g.,
Borus02) and a Bayesian approach, we uncover 22 representative Compton-thick
(CT; ) AGN candidates with good
signal-to-noise ratios as well as a large sample of 136 heavily obscured AGNs.
We also find an increasing CT fraction (\fct ) from low () to high
() redshift. Our CT candidates tend to show hard X-ray spectral shapes
and dust extinction in their SED fits, which may shed light on the connection
between AGN obscuration and host-galaxy evolution.Comment: 12 pages, 9 figures, accepted for publication in Ap
Effects of urease and nitrification inhibitors on soil N, nitrifier abundance and activity in a sandy loam soil
Inhibitors of urease and ammonia monooxygenase can limit the rate of conversion of urea to ammonia and ammonia to nitrate, respectively, potentially improving N fertilizer use efficiency and reducing gaseous losses. Winter wheat grown on a sandy soil in the UK was treated with urea fertilizer with the urease inhibitor N-(n-butyl) thiophosphoric triamide (NBPT), the nitrification inhibitor dicyandiamide (DCD) or a combination of both. The effects on soil microbial community diversity, the abundance of genes involved in nitrification and crop yields and net N recovery were compared. The only significant effect on N-cycle genes was a transient reduction in bacterial ammonia monooxygenase abundance following DCD application. However, overall crop yields and net N recovery were significantly lower in the urea treatments compared with an equivalent application of ammonium nitrate fertilizer, and significantly less for urea with DCD than the other urea treatments
Identification and Characterization of a Large Sample of Distant Active Dwarf Galaxies in XMM-SERVS
Active dwarf galaxies are important because they contribute to the evolution
of dwarf galaxies and can reveal their hosted massive black holes. However, the
sample size of such sources beyond the local universe is still highly limited.
In this work, we search for active dwarf galaxies in the recently completed
XMM-Spitzer Extragalactic Representative Volume Survey (XMM-SERVS). XMM-SERVS
is currently the largest medium-depth X-ray survey covering 13
in three extragalactic fields, which all have well-characterized
multi-wavelength information. After considering several factors that may lead
to misidentifications, we identify 73 active dwarf galaxies at , which
constitutes the currently largest X-ray-selected sample beyond the local
universe. Our sources are generally less obscured than predictions based on the
massive-AGN (active galactic nucleus) X-ray luminosity function and have a low
radio-excess fraction. We find that our sources reside in similar environments
to inactive dwarf galaxies. We further quantify the accretion distribution of
the dwarf-galaxy population after considering various selection effects and
find that it decreases with X-ray luminosity, but redshift evolution cannot be
statistically confirmed. Depending upon how we define an AGN, the active
fraction may or may not show a strong dependence on stellar mass. Their
Eddington ratios and X-ray bolometric corrections significantly deviate from
the expected relation, which is likely caused by several large underlying
systematic biases when estimating the relevant parameters for dwarf galaxies.
Throughout this work, we also highlight problems in reliably measuring
photometric redshifts and overcoming strong selection effects for distant
active dwarf galaxies.Comment: 34 pages, 21 figures, 6 tables, accepted for publication in Ap
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RNA-Seq Transcriptome Profiling Identifies CRISPLD2 as a Glucocorticoid Responsive Gene that Modulates Cytokine Function in Airway Smooth Muscle Cells
Asthma is a chronic inflammatory respiratory disease that affects over 300 million people worldwide. Glucocorticoids are a mainstay therapy for asthma because they exert anti-inflammatory effects in multiple lung tissues, including the airway smooth muscle (ASM). However, the mechanism by which glucocorticoids suppress inflammation in ASM remains poorly understood. Using RNA-Seq, a high-throughput sequencing method, we characterized transcriptomic changes in four primary human ASM cell lines that were treated with dexamethasone—a potent synthetic glucocorticoid (1 µM for 18 hours). Based on a Benjamini-Hochberg corrected p-value <0.05, we identified 316 differentially expressed genes, including both well known (DUSP1, KLF15, PER1, TSC22D3) and less investigated (C7, CCDC69, CRISPLD2) glucocorticoid-responsive genes. CRISPLD2, which encodes a secreted protein previously implicated in lung development and endotoxin regulation, was found to have SNPs that were moderately associated with inhaled corticosteroid resistance and bronchodilator response among asthma patients in two previously conducted genome-wide association studies. Quantitative RT-PCR and Western blotting showed that dexamethasone treatment significantly increased CRISPLD2 mRNA and protein expression in ASM cells. CRISPLD2 expression was also induced by the inflammatory cytokine IL1β, and small interfering RNA-mediated knockdown of CRISPLD2 further increased IL1β-induced expression of IL6 and IL8. Our findings offer a comprehensive view of the effect of a glucocorticoid on the ASM transcriptome and identify CRISPLD2 as an asthma pharmacogenetics candidate gene that regulates anti-inflammatory effects of glucocorticoids in the ASM
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